Natural Product: NPC265710

Natural Product ID:  NPC265710
Common Name:   Methylaplysinopsin
IUPAC Name:  
Synonyms:   Methylaplysinopsin; N-3'-Methylaplysinopsin
Molecular Formula:   C15H16N4O
Standard InCHIKey:  GXBMTEAMDOVNLO-TVSYJCFYSA-N
Standard InCHI:  InChI=1S/C15H16N4O/c1-16-15-18(2)13(14(20)19(15)3)8-10-9-17-12-7-5-4-6-11(10)12/h4-9,17H,1-3H3/b13-8+,16-15-
Canonical SMILES:  C/N=C/1N(C)C(=O)/C(=Cc2c[nH]c3c2cccc3)/N1C
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO33297 aplysina sp. Species Aplysinidae Eukaryota Okinawan PMID[7964781]
NPO20958 Smenospongia aurea Species Thorectidae Eukaryota Jamaican PMID[11975483]

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT292 Individual Protein Serotonin 2c (5-HT2c) receptor Homo sapiens Ki = 10000 nM 10869203
NPT261 Individual Protein Monoamine oxidase A Homo sapiens IC50 = 98 nM 14592480
NPT2776 Individual Protein Serotonin 1e (5-HT1e) receptor Homo sapiens Ki > 10000 nM 19928832
NPT1778 Individual Protein Serotonin 2a (5-HT2a) receptor Rattus norvegicus Ki > 10000 nM 18341287
NPT425 Individual Protein Serotonin 3a (5-HT3a) receptor Homo sapiens Ki = 1511 nM 23145909
NPT2 Others Unspecified Ratio IC50 = 92.32 23675610
NPT582 Individual Protein Monoamine oxidase B Homo sapiens IC50 = 9017 nM 17517833
NPT294 Individual Protein Serotonin 6 (5-HT6) receptor Homo sapiens Ki = 1716 nM 20100877
NPT91 Cell Line KB Homo sapiens IC50 = 6.7 ug/ml PubChem BioAssay data set
NPT137 Cell Line L1210 Mus musculus IC50 = 3.5 ug/ml PubChem BioAssay data set
NPT291 Individual Protein Serotonin 2b (5-HT2b) receptor Homo sapiens Ki = 4554 nM 25646964

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC265710 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.9938 High Similarity NPC16659
0.9812 High Similarity NPC473380
0.9812 High Similarity NPC240088
0.9075 High Similarity NPC188821
0.9075 High Similarity NPC474180
0.8556 High Similarity NPC474389
0.8452 Intermediate Similarity NPC49217
0.8242 Intermediate Similarity NPC200214
0.8239 Intermediate Similarity NPC73767
0.8214 Intermediate Similarity NPC470204
0.821 Intermediate Similarity NPC314372
0.8199 Intermediate Similarity NPC190296
0.8166 Intermediate Similarity NPC470203
0.816 Intermediate Similarity NPC143872
0.8125 Intermediate Similarity NPC110126
0.8113 Intermediate Similarity NPC84911
0.8111 Intermediate Similarity NPC213629
0.8098 Intermediate Similarity NPC470440
0.8085 Intermediate Similarity NPC473376
0.8075 Intermediate Similarity NPC469784
0.8075 Intermediate Similarity NPC469779
0.8075 Intermediate Similarity NPC469783
0.8075 Intermediate Similarity NPC469780
0.8075 Intermediate Similarity NPC469767
0.8075 Intermediate Similarity NPC469761
0.8075 Intermediate Similarity NPC469768
0.8068 Intermediate Similarity NPC11126
0.805 Intermediate Similarity NPC261195
0.805 Intermediate Similarity NPC29886
0.805 Intermediate Similarity NPC96102
0.8025 Intermediate Similarity NPC469766
0.8012 Intermediate Similarity NPC53947
0.8012 Intermediate Similarity NPC24678
0.8012 Intermediate Similarity NPC105818
0.8011 Intermediate Similarity NPC284775
0.8 Intermediate Similarity NPC105127
0.8 Intermediate Similarity NPC94752
0.7989 Intermediate Similarity NPC477003
0.7988 Intermediate Similarity NPC204141
0.7988 Intermediate Similarity NPC159856
0.7958 Intermediate Similarity NPC116555
0.7956 Intermediate Similarity NPC17059
0.7944 Intermediate Similarity NPC308931
0.7944 Intermediate Similarity NPC99939
0.7941 Intermediate Similarity NPC135141
0.7941 Intermediate Similarity NPC92796
0.7939 Intermediate Similarity NPC288838
0.7927 Intermediate Similarity NPC54981
0.7923 Intermediate Similarity NPC476460
0.7917 Intermediate Similarity NPC469760
0.7917 Intermediate Similarity NPC469786
0.7917 Intermediate Similarity NPC469763
0.7917 Intermediate Similarity NPC259644
0.7917 Intermediate Similarity NPC469765
0.7917 Intermediate Similarity NPC73952
0.7917 Intermediate Similarity NPC25008
0.7895 Intermediate Similarity NPC122141
0.7892 Intermediate Similarity NPC471957
0.7889 Intermediate Similarity NPC228835
0.787 Intermediate Similarity NPC75540
0.787 Intermediate Similarity NPC212376
0.787 Intermediate Similarity NPC211572
0.787 Intermediate Similarity NPC80597
0.787 Intermediate Similarity NPC70922
0.7861 Intermediate Similarity NPC171317
0.7853 Intermediate Similarity NPC279081
0.7844 Intermediate Similarity NPC321911
0.7842 Intermediate Similarity NPC317701
0.7841 Intermediate Similarity NPC161861
0.7835 Intermediate Similarity NPC320968
0.7803 Intermediate Similarity NPC478182
0.7802 Intermediate Similarity NPC476527
0.7799 Intermediate Similarity NPC82295
0.7789 Intermediate Similarity NPC474195
0.7784 Intermediate Similarity NPC469811
0.7784 Intermediate Similarity NPC201380
0.7784 Intermediate Similarity NPC179787
0.7778 Intermediate Similarity NPC475736
0.7772 Intermediate Similarity NPC71238
0.7766 Intermediate Similarity NPC473640
0.7755 Intermediate Similarity NPC54744
0.7744 Intermediate Similarity NPC230002
0.7733 Intermediate Similarity NPC293487
0.7725 Intermediate Similarity NPC100321
0.7725 Intermediate Similarity NPC63545
0.7725 Intermediate Similarity NPC293917
0.7719 Intermediate Similarity NPC469785
0.7709 Intermediate Similarity NPC145885
0.7709 Intermediate Similarity NPC14113
0.7709 Intermediate Similarity NPC84827
0.7705 Intermediate Similarity NPC135601
0.7705 Intermediate Similarity NPC141612
0.7705 Intermediate Similarity NPC17273
0.7701 Intermediate Similarity NPC478184
0.768 Intermediate Similarity NPC191415
0.7677 Intermediate Similarity NPC470732
0.7677 Intermediate Similarity NPC470731
0.7674 Intermediate Similarity NPC469762
0.7674 Intermediate Similarity NPC216643
0.7669 Intermediate Similarity NPC125746
0.7665 Intermediate Similarity NPC282247
0.7657 Intermediate Similarity NPC42372
0.7654 Intermediate Similarity NPC198988
0.7647 Intermediate Similarity NPC326422
0.7647 Intermediate Similarity NPC216713
0.7644 Intermediate Similarity NPC475506
0.7638 Intermediate Similarity NPC267811
0.7637 Intermediate Similarity NPC470205
0.7635 Intermediate Similarity NPC474196
0.7614 Intermediate Similarity NPC471194
0.7614 Intermediate Similarity NPC471193
0.7614 Intermediate Similarity NPC6865
0.7614 Intermediate Similarity NPC160105
0.7614 Intermediate Similarity NPC153980
0.7607 Intermediate Similarity NPC218268
0.7607 Intermediate Similarity NPC325252
0.7604 Intermediate Similarity NPC155143
0.7602 Intermediate Similarity NPC325903
0.76 Intermediate Similarity NPC311276
0.76 Intermediate Similarity NPC317105
0.7598 Intermediate Similarity NPC293216
0.7596 Intermediate Similarity NPC21429
0.7582 Intermediate Similarity NPC307191
0.7572 Intermediate Similarity NPC236711
0.7563 Intermediate Similarity NPC72956
0.7558 Intermediate Similarity NPC34844
0.7557 Intermediate Similarity NPC280864
0.7557 Intermediate Similarity NPC17751
0.7556 Intermediate Similarity NPC280852
0.7554 Intermediate Similarity NPC133003
0.7554 Intermediate Similarity NPC280290
0.7553 Intermediate Similarity NPC304203
0.7544 Intermediate Similarity NPC470823
0.7543 Intermediate Similarity NPC478185
0.7543 Intermediate Similarity NPC225018
0.7543 Intermediate Similarity NPC282231
0.7541 Intermediate Similarity NPC102755
0.7529 Intermediate Similarity NPC318065
0.7529 Intermediate Similarity NPC206819
0.7529 Intermediate Similarity NPC56765
0.7528 Intermediate Similarity NPC194411
0.7527 Intermediate Similarity NPC91179
0.7525 Intermediate Similarity NPC473218
0.7525 Intermediate Similarity NPC470702
0.7514 Intermediate Similarity NPC474561
0.7514 Intermediate Similarity NPC478183
0.7514 Intermediate Similarity NPC59269
0.7514 Intermediate Similarity NPC470509
0.7514 Intermediate Similarity NPC49954
0.7513 Intermediate Similarity NPC294693
0.75 Intermediate Similarity NPC40779
0.75 Intermediate Similarity NPC281094
0.75 Intermediate Similarity NPC165495
0.75 Intermediate Similarity NPC141926
0.7488 Intermediate Similarity NPC69843
0.7487 Intermediate Similarity NPC470703
0.7486 Intermediate Similarity NPC279918
0.7486 Intermediate Similarity NPC131718
0.7486 Intermediate Similarity NPC54214
0.7473 Intermediate Similarity NPC233050
0.7473 Intermediate Similarity NPC126709
0.7473 Intermediate Similarity NPC276540
0.7473 Intermediate Similarity NPC248041
0.7471 Intermediate Similarity NPC286427
0.7471 Intermediate Similarity NPC299594
0.747 Intermediate Similarity NPC88097
0.7459 Intermediate Similarity NPC267885
0.7459 Intermediate Similarity NPC15102
0.7455 Intermediate Similarity NPC150259
0.7449 Intermediate Similarity NPC54420
0.7448 Intermediate Similarity NPC477004
0.7444 Intermediate Similarity NPC314603
0.7442 Intermediate Similarity NPC470233
0.7435 Intermediate Similarity NPC174281
0.7435 Intermediate Similarity NPC475286
0.7433 Intermediate Similarity NPC321708
0.743 Intermediate Similarity NPC91895
0.743 Intermediate Similarity NPC32534
0.7429 Intermediate Similarity NPC221786
0.7429 Intermediate Similarity NPC475990
0.7429 Intermediate Similarity NPC474880
0.7429 Intermediate Similarity NPC41257
0.7429 Intermediate Similarity NPC230869
0.7416 Intermediate Similarity NPC114637
0.7415 Intermediate Similarity NPC476817
0.7413 Intermediate Similarity NPC471192
0.7407 Intermediate Similarity NPC22079
0.7407 Intermediate Similarity NPC47190
0.7403 Intermediate Similarity NPC110500
0.7403 Intermediate Similarity NPC37423
0.7403 Intermediate Similarity NPC149155
0.7403 Intermediate Similarity NPC203468
0.7403 Intermediate Similarity NPC275305
0.7403 Intermediate Similarity NPC317054
0.7401 Intermediate Similarity NPC247987
0.7401 Intermediate Similarity NPC90723
0.7396 Intermediate Similarity NPC470499
0.7391 Intermediate Similarity NPC243381
0.7391 Intermediate Similarity NPC275292
0.7391 Intermediate Similarity NPC470677

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC265710 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
0.8125 Intermediate Similarity NPD786 Approved
0.8103 Intermediate Similarity NPD4128 Approved
0.8079 Intermediate Similarity NPD1707 Approved
0.8079 Intermediate Similarity NPD1708 Approved
0.805 Intermediate Similarity NPD198 Clinical (unspecified phase)
0.8042 Intermediate Similarity NPD2008 Discontinued
0.8012 Intermediate Similarity NPD2172 Phase 1
0.8011 Intermediate Similarity NPD4181 Approved
0.8 Intermediate Similarity NPD8493 Clinical (unspecified phase)
0.7958 Intermediate Similarity NPD2442 Approved
0.7958 Intermediate Similarity NPD2443 Approved
0.7933 Intermediate Similarity NPD1332 Clinical (unspecified phase)
0.7914 Intermediate Similarity NPD1722 Approved
0.7903 Intermediate Similarity NPD2880 Discontinued
0.7901 Intermediate Similarity NPD5820 Clinical (unspecified phase)
0.7877 Intermediate Similarity NPD1895 Discontinued
0.7857 Intermediate Similarity NPD3961 Discontinued
0.7853 Intermediate Similarity NPD4075 Phase 2
0.7844 Intermediate Similarity NPD3100 Discontinued
0.7826 Intermediate Similarity NPD6180 Clinical (unspecified phase)
0.7802 Intermediate Similarity NPD6217 Discontinued
0.7795 Intermediate Similarity NPD2411 Approved
0.776 Intermediate Similarity NPD3486 Clinical (unspecified phase)
0.7738 Intermediate Similarity NPD4374 Clinical (unspecified phase)
0.7732 Intermediate Similarity NPD2408 Discontinued
0.7725 Intermediate Similarity NPD7621 Clinical (unspecified phase)
0.7714 Intermediate Similarity NPD2639 Approved
0.7714 Intermediate Similarity NPD2642 Approved
0.7713 Intermediate Similarity NPD6664 Approved
0.7705 Intermediate Similarity NPD4426 Clinical (unspecified phase)
0.7705 Intermediate Similarity NPD7026 Phase 2
0.767 Intermediate Similarity NPD2390 Clinical (unspecified phase)
0.767 Intermediate Similarity NPD2185 Clinical (unspecified phase)
0.765 Intermediate Similarity NPD5199 Approved
0.765 Intermediate Similarity NPD5198 Approved
0.7626 Intermediate Similarity NPD7971 Clinical (unspecified phase)
0.7626 Intermediate Similarity NPD7970 Approved
0.7624 Intermediate Similarity NPD6595 Phase 3
0.7614 Intermediate Similarity NPD1248 Discontinued
0.7606 Intermediate Similarity NPD7619 Phase 3
0.7606 Intermediate Similarity NPD7618 Phase 3
0.7596 Intermediate Similarity NPD3607 Clinical (unspecified phase)
0.7586 Intermediate Similarity NPD1404 Approved
0.7586 Intermediate Similarity NPD1403 Approved
0.7584 Intermediate Similarity NPD3347 Clinical (unspecified phase)
0.7568 Intermediate Similarity NPD2009 Clinical (unspecified phase)
0.7566 Intermediate Similarity NPD2960 Clinical (unspecified phase)
0.7566 Intermediate Similarity NPD6278 Clinical (unspecified phase)
0.7552 Intermediate Similarity NPD7903 Clinical (unspecified phase)
0.7551 Intermediate Similarity NPD1600 Suspended
0.7545 Intermediate Similarity NPD2007 Clinical (unspecified phase)
0.7528 Intermediate Similarity NPD4184 Clinical (unspecified phase)
0.7527 Intermediate Similarity NPD6277 Clinical (unspecified phase)
0.7527 Intermediate Similarity NPD7175 Phase 1
0.7514 Intermediate Similarity NPD2793 Discontinued
0.7514 Intermediate Similarity NPD6203 Clinical (unspecified phase)
0.7513 Intermediate Similarity NPD7809 Clinical (unspecified phase)
0.75 Intermediate Similarity NPD2837 Discontinued
0.7487 Intermediate Similarity NPD1982 Phase 1
0.7486 Intermediate Similarity NPD4649 Clinical (unspecified phase)
0.7475 Intermediate Similarity NPD8013 Clinical (unspecified phase)
0.7472 Intermediate Similarity NPD5069 Clinical (unspecified phase)
0.7463 Intermediate Similarity NPD8257 Approved
0.7463 Intermediate Similarity NPD8258 Clinical (unspecified phase)
0.7463 Intermediate Similarity NPD8256 Approved
0.7459 Intermediate Similarity NPD749 Clinical (unspecified phase)
0.7459 Intermediate Similarity NPD6610 Clinical (unspecified phase)
0.7449 Intermediate Similarity NPD1506 Discontinued
0.7443 Intermediate Similarity NPD6771 Discontinued
0.7432 Intermediate Similarity NPD5508 Phase 1
0.7426 Intermediate Similarity NPD6470 Phase 3
0.7418 Intermediate Similarity NPD2144 Approved
0.7407 Intermediate Similarity NPD4615 Phase 2
0.7407 Intermediate Similarity NPD4922 Phase 2
0.7403 Intermediate Similarity NPD482 Approved
0.7401 Intermediate Similarity NPD3323 Discontinued
0.7398 Intermediate Similarity NPD4023 Clinical (unspecified phase)
0.7394 Intermediate Similarity NPD5685 Approved
0.7394 Intermediate Similarity NPD5686 Approved
0.7394 Intermediate Similarity NPD5145 Clinical (unspecified phase)
0.7389 Intermediate Similarity NPD6828 Phase 2
0.7389 Intermediate Similarity NPD6827 Clinical (unspecified phase)
0.7377 Intermediate Similarity NPD3341 Clinical (unspecified phase)
0.7374 Intermediate Similarity NPD2640 Approved
0.7374 Intermediate Similarity NPD2641 Approved
0.7368 Intermediate Similarity NPD460 Discontinued
0.736 Intermediate Similarity NPD7445 Phase 1
0.736 Intermediate Similarity NPD1313 Approved
0.7351 Intermediate Similarity NPD5728 Clinical (unspecified phase)
0.735 Intermediate Similarity NPD7594 Clinical (unspecified phase)
0.735 Intermediate Similarity NPD8458 Clinical (unspecified phase)
0.7337 Intermediate Similarity NPD4637 Clinical (unspecified phase)
0.7333 Intermediate Similarity NPD2881 Approved
0.7333 Intermediate Similarity NPD2879 Approved
0.7333 Intermediate Similarity NPD3015 Discontinued
0.7326 Intermediate Similarity NPD3378 Clinical (unspecified phase)
0.7322 Intermediate Similarity NPD7111 Discontinued
0.7322 Intermediate Similarity NPD3505 Approved
0.7322 Intermediate Similarity NPD3506 Approved
0.7321 Intermediate Similarity NPD3943 Clinical (unspecified phase)
0.7314 Intermediate Similarity NPD2580 Discontinued
0.7314 Intermediate Similarity NPD2150 Discontinued
0.7313 Intermediate Similarity NPD8488 Clinical (unspecified phase)
0.7312 Intermediate Similarity NPD7564 Discontinued
0.7308 Intermediate Similarity NPD6165 Phase 2
0.7308 Intermediate Similarity NPD5065 Approved
0.7308 Intermediate Similarity NPD6164 Phase 2
0.7302 Intermediate Similarity NPD3871 Clinical (unspecified phase)
0.7302 Intermediate Similarity NPD3870 Clinical (unspecified phase)
0.7299 Intermediate Similarity NPD8047 Clinical (unspecified phase)
0.7297 Intermediate Similarity NPD3038 Discontinued
0.7293 Intermediate Similarity NPD1567 Clinical (unspecified phase)
0.7291 Intermediate Similarity NPD8406 Clinical (unspecified phase)
0.7283 Intermediate Similarity NPD4079 Approved
0.7283 Intermediate Similarity NPD4463 Approved
0.7283 Intermediate Similarity NPD4462 Approved
0.7283 Intermediate Similarity NPD4076 Approved
0.7278 Intermediate Similarity NPD4779 Clinical (unspecified phase)
0.7278 Intermediate Similarity NPD2333 Discontinued
0.7268 Intermediate Similarity NPD2405 Phase 3
0.7268 Intermediate Similarity NPD6044 Discontinued
0.7263 Intermediate Similarity NPD1658 Discontinued
0.7259 Intermediate Similarity NPD6288 Clinical (unspecified phase)
0.7259 Intermediate Similarity NPD8272 Phase 2
0.7258 Intermediate Similarity NPD2094 Phase 2
0.7258 Intermediate Similarity NPD5105 Approved
0.7258 Intermediate Similarity NPD2092 Phase 2
0.7258 Intermediate Similarity NPD5106 Approved
0.7258 Intermediate Similarity NPD2095 Phase 2
0.7253 Intermediate Similarity NPD750 Phase 2
0.7245 Intermediate Similarity NPD6268 Phase 1
0.7245 Intermediate Similarity NPD6269 Clinical (unspecified phase)
0.7243 Intermediate Similarity NPD5962 Phase 2
0.7236 Intermediate Similarity NPD6459 Phase 2
0.7235 Intermediate Similarity NPD4047 Discontinued
0.7225 Intermediate Similarity NPD3430 Approved
0.7225 Intermediate Similarity NPD3431 Approved
0.7222 Intermediate Similarity NPD5611 Phase 2
0.7219 Intermediate Similarity NPD2096 Phase 2
0.7219 Intermediate Similarity NPD2091 Phase 2
0.7209 Intermediate Similarity NPD1683 Approved
0.7207 Intermediate Similarity NPD3583 Phase 2
0.7202 Intermediate Similarity NPD7023 Clinical (unspecified phase)
0.7198 Intermediate Similarity NPD3610 Approved
0.7198 Intermediate Similarity NPD3609 Approved
0.7193 Intermediate Similarity NPD5254 Discontinued
0.7189 Intermediate Similarity NPD2930 Clinical (unspecified phase)
0.7189 Intermediate Similarity NPD1327 Discontinued
0.7188 Intermediate Similarity NPD3485 Clinical (unspecified phase)
0.7186 Intermediate Similarity NPD3905 Phase 3
0.7184 Intermediate Similarity NPD1029 Clinical (unspecified phase)
0.7184 Intermediate Similarity NPD1030 Approved
0.7184 Intermediate Similarity NPD1027 Approved
0.7174 Intermediate Similarity NPD7402 Clinical (unspecified phase)
0.7172 Intermediate Similarity NPD7208 Approved
0.7172 Intermediate Similarity NPD7209 Approved
0.7172 Intermediate Similarity NPD7207 Approved
0.7167 Intermediate Similarity NPD509 Phase 3
0.7166 Intermediate Similarity NPD3320 Approved
0.7166 Intermediate Similarity NPD3318 Approved
0.7166 Intermediate Similarity NPD3319 Phase 1
0.7165 Intermediate Similarity NPD5446 Phase 2
0.7165 Intermediate Similarity NPD3830 Phase 1
0.7163 Intermediate Similarity NPD6849 Phase 2
0.7163 Intermediate Similarity NPD6850 Phase 2
0.7152 Intermediate Similarity NPD803 Phase 1
0.7143 Intermediate Similarity NPD2875 Clinical (unspecified phase)
0.7143 Intermediate Similarity NPD4902 Discontinued
0.7143 Intermediate Similarity NPD1262 Discovery
0.7143 Intermediate Similarity NPD4024 Phase 3
0.7135 Intermediate Similarity NPD1272 Clinical (unspecified phase)
0.7134 Intermediate Similarity NPD3654 Approved
0.7119 Intermediate Similarity NPD473 Clinical (unspecified phase)
0.7113 Intermediate Similarity NPD2316 Clinical (unspecified phase)
0.7107 Intermediate Similarity NPD5017 Discontinued
0.7105 Intermediate Similarity NPD6141 Clinical (unspecified phase)
0.7105 Intermediate Similarity NPD4988 Discontinued
0.7105 Intermediate Similarity NPD7394 Phase 2
0.7105 Intermediate Similarity NPD3002 Clinical (unspecified phase)
0.7102 Intermediate Similarity NPD1303 Phase 1
0.71 Intermediate Similarity NPD6838 Clinical (unspecified phase)
0.71 Intermediate Similarity NPD6328 Clinical (unspecified phase)
0.7097 Intermediate Similarity NPD2590 Clinical (unspecified phase)
0.7094 Intermediate Similarity NPD7656 Approved
0.7094 Intermediate Similarity NPD7657 Approved
0.7094 Intermediate Similarity NPD7164 Discontinued
0.7092 Intermediate Similarity NPD5854 Approved
0.7091 Intermediate Similarity NPD3476 Approved
0.7091 Intermediate Similarity NPD3475 Approved
0.7079 Intermediate Similarity NPD7998 Clinical (unspecified phase)
0.7077 Intermediate Similarity NPD1952 Discontinued
0.7072 Intermediate Similarity NPD2915 Discontinued
0.7072 Intermediate Similarity NPD5744 Clinical (unspecified phase)
0.7069 Intermediate Similarity NPD4547 Phase 3
0.7068 Intermediate Similarity NPD8110 Clinical (unspecified phase)
0.7065 Intermediate Similarity NPD2510 Approved
0.7065 Intermediate Similarity NPD966 Clinical (unspecified phase)
0.7065 Intermediate Similarity NPD2509 Approved
0.7062 Intermediate Similarity NPD5853 Phase 3
0.7062 Intermediate Similarity NPD5855 Phase 3

Structure

External Identifiers

PubChem CID  
ChEMBL   CHEMBL512332
ZINC  

Physicochemical Properties

Molecular Weight:  268.13
ALogP:  -1.0218
MLogP:  2.56
XLogP:  2.922
# Rotatable Bonds:  4
Polar Surface Area:  51.7
# H-Bond Aceptor:  5
# H-Bond Donor:  1
# Rings:  3
# Heavy Atoms:  20

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Biological Activities  
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