Natural Product: NPC156348

Natural Product ID:  NPC156348
Common Name:   Cytochalasin Z5
IUPAC Name:  
Synonyms:   Cytochalasin Z5
Molecular Formula:   C29H37NO6
Standard InCHIKey:  AJMKPZXRIKVSAQ-LFOGIAMQSA-N
Standard InCHI:  InChI=1S/C29H37NO6/c1-17-6-4-8-21(31)14-15-25(33)36-29-23(9-5-7-17)27(34)19(3)18(2)26(29)24(30-28(29)35)16-20-10-12-22(32)13-11-20/h5,9-15,17-18,21,23-24,26-27,31-32,34H,3-4,6-8,16H2,1-2H3,(H,30,35)/b9-5+,15-14+/t17-,18-,21-,23+,24+,26+,27-,29-/m1/s1
Canonical SMILES:  C[C@@H]1CCC[C@@H](O)/C=C/C(=O)O[C@@]23[C@@H](/C=C/C1)[C@H](O)C(=C)[C@H]([C@H]3[C@@H](N=C2O)Cc1ccc(cc1)O)C
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO5591 Fucus spiralis Species Fucaceae Eukaryota UNPD*
NPO1607 Croton rhamnifolius Species Euphorbiaceae Eukaryota UNPD*
NPO2518 Crinum kirkii Species Amaryllidaceae Eukaryota UNPD*
NPO15583 Tripodanthus acutifolius Species Loranthaceae Eukaryota UNPD*
NPO8472 Knightia deplanchei Species Proteaceae Eukaryota UNPD*
NPO6377 Cocculus diversifolius Species Menispermaceae Eukaryota UNPD*
NPO3664 Mesembryanthemum anatomicum Species Aizoaceae Eukaryota UNPD*
NPO2361 Aconitum brevicalcaratum Species Ranunculaceae Eukaryota UNPD*
NPO3146 Ammodendron conollyi Species Fabaceae Eukaryota UNPD*
NPO351 Cirsium dipsacolepis Species Asteraceae Eukaryota UNPD*
NPO8840 Ptilidium ciliare Species Ptilidiaceae Eukaryota UNPD*
NPO1071 Parerythropodium fulvum NA NA NA UNPD*
NPO8585 Verpa digitaliformis Species Morchellaceae Eukaryota UNPD*
NPO3936 Malva sylvestris Species Malvaceae Eukaryota UNPD*
NPO6520 Myrica multiflora Species Myricaceae Eukaryota UNPD*
NPO6776 Trifolium apertum Species Fabaceae Eukaryota UNPD*
NPO20132 Scutellaria seleriana Species Lamiaceae Eukaryota UNPD*
NPO2747 Hypericum triquetrifolium Species Hypericaceae Eukaryota UNPD*
NPO2342 Cytisus scoparius Species Fabaceae Eukaryota UNPD*
NPO4082 Ophiarthrum elegans Species Ophiocomidae Eukaryota UNPD*
NPO1308 Veronica pectinata Species Plantaginaceae Eukaryota UNPD*
NPO5980 Eria subsessilis Species Orchidaceae Eukaryota UNPD*
NPO10021 Nerium oleander Species Apocynaceae Eukaryota UNPD*
NPO13325 Plantago lanceolata Species Plantaginaceae Eukaryota UNPD*
NPO5197 Streptomyces eurythermus Species Streptomycetaceae Bacteria UNPD*
NPO26266 Isodon japonicus Species Lamiaceae Eukaryota UNPD*
NPO715 Teucrium pestalozzae Species Lamiaceae Eukaryota UNPD*
NPO4253 Viguiera annua Species Asteraceae Eukaryota UNPD*
NPO6974 Solanum racemigerum Species Solanaceae Eukaryota UNPD*
NPO7097 Rhynchosporium orthosporum Species NA Eukaryota UNPD*

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT140 Organism Artemia Artemia Activity = 21 % 14695792

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC156348 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.9412 High Similarity NPC15506
0.9184 High Similarity NPC31171
0.9184 High Similarity NPC237240
0.9 High Similarity NPC201692
0.8867 High Similarity NPC173934
0.8784 High Similarity NPC108852
0.8784 High Similarity NPC261709
0.8784 High Similarity NPC111586
0.865 High Similarity NPC477115
0.8255 Intermediate Similarity NPC90693
0.8255 Intermediate Similarity NPC64897
0.8163 Intermediate Similarity NPC295478
0.805 Intermediate Similarity NPC4108
0.8026 Intermediate Similarity NPC175870
0.8013 Intermediate Similarity NPC262216
0.7987 Intermediate Similarity NPC239770
0.7911 Intermediate Similarity NPC313414
0.7905 Intermediate Similarity NPC278097
0.7898 Intermediate Similarity NPC49565
0.7778 Intermediate Similarity NPC228511
0.7727 Intermediate Similarity NPC113325
0.7727 Intermediate Similarity NPC279045
0.7714 Intermediate Similarity NPC474607
0.767 Intermediate Similarity NPC474650
0.7651 Intermediate Similarity NPC476194
0.7625 Intermediate Similarity NPC204644
0.7593 Intermediate Similarity NPC320734
0.7557 Intermediate Similarity NPC475794
0.7547 Intermediate Similarity NPC470617
0.7547 Intermediate Similarity NPC470616
0.7546 Intermediate Similarity NPC476744
0.7532 Intermediate Similarity NPC42423
0.7514 Intermediate Similarity NPC477816
0.7485 Intermediate Similarity NPC476743
0.7484 Intermediate Similarity NPC469360
0.7484 Intermediate Similarity NPC116742
0.7484 Intermediate Similarity NPC139243
0.7483 Intermediate Similarity NPC10154
0.7483 Intermediate Similarity NPC474532
0.7483 Intermediate Similarity NPC265413
0.7468 Intermediate Similarity NPC322526
0.7452 Intermediate Similarity NPC6570
0.7452 Intermediate Similarity NPC64205
0.7421 Intermediate Similarity NPC197921
0.7414 Intermediate Similarity NPC474953
0.741 Intermediate Similarity NPC476741
0.7405 Intermediate Similarity NPC473055
0.7405 Intermediate Similarity NPC473052
0.7394 Intermediate Similarity NPC182119
0.7375 Intermediate Similarity NPC91953
0.7362 Intermediate Similarity NPC26045
0.736 Intermediate Similarity NPC32154
0.7358 Intermediate Similarity NPC471201
0.7349 Intermediate Similarity NPC476742
0.7348 Intermediate Similarity NPC474661
0.7348 Intermediate Similarity NPC475919
0.7345 Intermediate Similarity NPC241704
0.7337 Intermediate Similarity NPC471203
0.7337 Intermediate Similarity NPC235460
0.7321 Intermediate Similarity NPC207675
0.7321 Intermediate Similarity NPC212699
0.7321 Intermediate Similarity NPC217801
0.7317 Intermediate Similarity NPC163898
0.7316 Intermediate Similarity NPC475768
0.7301 Intermediate Similarity NPC235557
0.7299 Intermediate Similarity NPC304846
0.7283 Intermediate Similarity NPC54125
0.7283 Intermediate Similarity NPC89199
0.7273 Intermediate Similarity NPC88378
0.7273 Intermediate Similarity NPC211713
0.7273 Intermediate Similarity NPC61181
0.7262 Intermediate Similarity NPC275027
0.7261 Intermediate Similarity NPC478255
0.7261 Intermediate Similarity NPC328070
0.7256 Intermediate Similarity NPC25491
0.7256 Intermediate Similarity NPC96447
0.7255 Intermediate Similarity NPC472414
0.7251 Intermediate Similarity NPC329837
0.725 Intermediate Similarity NPC471283
0.7244 Intermediate Similarity NPC288290
0.7237 Intermediate Similarity NPC327070
0.7233 Intermediate Similarity NPC11266
0.7232 Intermediate Similarity NPC110374
0.7232 Intermediate Similarity NPC474051
0.7232 Intermediate Similarity NPC289743
0.7226 Intermediate Similarity NPC71271
0.7226 Intermediate Similarity NPC103533
0.7222 Intermediate Similarity NPC271494
0.7222 Intermediate Similarity NPC155192
0.7222 Intermediate Similarity NPC473591
0.7216 Intermediate Similarity NPC471165
0.7212 Intermediate Similarity NPC132771
0.7208 Intermediate Similarity NPC475933
0.7208 Intermediate Similarity NPC470158
0.7197 Intermediate Similarity NPC45191
0.7195 Intermediate Similarity NPC252133
0.7195 Intermediate Similarity NPC186296
0.7195 Intermediate Similarity NPC310621
0.7193 Intermediate Similarity NPC195766
0.7193 Intermediate Similarity NPC206736
0.7191 Intermediate Similarity NPC203005
0.7188 Intermediate Similarity NPC182217
0.7188 Intermediate Similarity NPC233350
0.7188 Intermediate Similarity NPC70680
0.7179 Intermediate Similarity NPC93632
0.7178 Intermediate Similarity NPC159387
0.7178 Intermediate Similarity NPC137501
0.7178 Intermediate Similarity NPC154262
0.7178 Intermediate Similarity NPC304110
0.7178 Intermediate Similarity NPC7518
0.7178 Intermediate Similarity NPC27518
0.7171 Intermediate Similarity NPC474862
0.717 Intermediate Similarity NPC185777
0.7161 Intermediate Similarity NPC476971
0.7161 Intermediate Similarity NPC476972
0.716 Intermediate Similarity NPC77310
0.716 Intermediate Similarity NPC182249
0.716 Intermediate Similarity NPC151946
0.716 Intermediate Similarity NPC171134
0.716 Intermediate Similarity NPC76032
0.716 Intermediate Similarity NPC132723
0.716 Intermediate Similarity NPC321638
0.716 Intermediate Similarity NPC472547
0.716 Intermediate Similarity NPC328273
0.716 Intermediate Similarity NPC321184
0.7159 Intermediate Similarity NPC182257
0.7158 Intermediate Similarity NPC327699
0.7152 Intermediate Similarity NPC251062
0.7152 Intermediate Similarity NPC184464
0.7152 Intermediate Similarity NPC235294
0.7152 Intermediate Similarity NPC471824
0.7152 Intermediate Similarity NPC46137
0.7151 Intermediate Similarity NPC1291
0.7151 Intermediate Similarity NPC115343
0.7151 Intermediate Similarity NPC69360
0.7143 Intermediate Similarity NPC39549
0.7143 Intermediate Similarity NPC329717
0.7143 Intermediate Similarity NPC471988
0.7143 Intermediate Similarity NPC470733
0.7143 Intermediate Similarity NPC38099
0.7143 Intermediate Similarity NPC476699
0.7143 Intermediate Similarity NPC275839
0.7143 Intermediate Similarity NPC90984
0.7143 Intermediate Similarity NPC198741
0.7143 Intermediate Similarity NPC26954
0.7143 Intermediate Similarity NPC471872
0.7143 Intermediate Similarity NPC154485
0.7134 Intermediate Similarity NPC30174
0.7134 Intermediate Similarity NPC86257
0.7134 Intermediate Similarity NPC67467
0.7134 Intermediate Similarity NPC35212
0.7126 Intermediate Similarity NPC472937
0.7126 Intermediate Similarity NPC470330
0.7126 Intermediate Similarity NPC269668
0.7126 Intermediate Similarity NPC472938
0.7126 Intermediate Similarity NPC472936
0.7125 Intermediate Similarity NPC135127
0.7125 Intermediate Similarity NPC67247
0.7125 Intermediate Similarity NPC208725
0.7125 Intermediate Similarity NPC68517
0.7124 Intermediate Similarity NPC325301
0.7115 Intermediate Similarity NPC173150
0.7115 Intermediate Similarity NPC58061
0.7115 Intermediate Similarity NPC288416
0.7115 Intermediate Similarity NPC106677
0.7115 Intermediate Similarity NPC471881
0.7115 Intermediate Similarity NPC35288
0.7115 Intermediate Similarity NPC471882
0.7115 Intermediate Similarity NPC66331
0.7115 Intermediate Similarity NPC156692
0.7115 Intermediate Similarity NPC45224
0.7111 Intermediate Similarity NPC475345
0.711 Intermediate Similarity NPC202839
0.711 Intermediate Similarity NPC66678
0.7108 Intermediate Similarity NPC469701
0.7101 Intermediate Similarity NPC470619
0.7101 Intermediate Similarity NPC145527
0.7101 Intermediate Similarity NPC267469
0.7101 Intermediate Similarity NPC116292
0.7101 Intermediate Similarity NPC87630
0.7101 Intermediate Similarity NPC179128
0.7101 Intermediate Similarity NPC470916
0.7101 Intermediate Similarity NPC208785
0.7101 Intermediate Similarity NPC470618
0.7099 Intermediate Similarity NPC216940
0.7099 Intermediate Similarity NPC155963
0.7099 Intermediate Similarity NPC475482
0.7099 Intermediate Similarity NPC22676
0.7099 Intermediate Similarity NPC198621
0.7099 Intermediate Similarity NPC281780
0.7097 Intermediate Similarity NPC94499
0.7097 Intermediate Similarity NPC45821
0.7097 Intermediate Similarity NPC476970
0.7095 Intermediate Similarity NPC329969
0.7095 Intermediate Similarity NPC187678
0.7083 Intermediate Similarity NPC477483
0.7083 Intermediate Similarity NPC81835
0.7083 Intermediate Similarity NPC102934
0.7083 Intermediate Similarity NPC236166
0.7083 Intermediate Similarity NPC252402

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC156348 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
0.9184 High Similarity NPD7274 Clinical (unspecified phase)
0.7412 Intermediate Similarity NPD7975 Clinical (unspecified phase)
0.7333 Intermediate Similarity NPD7314 Clinical (unspecified phase)
0.7325 Intermediate Similarity NPD2238 Phase 2
0.7256 Intermediate Similarity NPD6667 Approved
0.7256 Intermediate Similarity NPD6666 Approved
0.7241 Intermediate Similarity NPD7315 Approved
0.7239 Intermediate Similarity NPD3400 Discontinued
0.7225 Intermediate Similarity NPD4666 Phase 3
0.7219 Intermediate Similarity NPD6072 Discontinued
0.7168 Intermediate Similarity NPD5709 Phase 3
0.7135 Intermediate Similarity NPD5772 Approved
0.7135 Intermediate Similarity NPD5773 Approved
0.7126 Intermediate Similarity NPD7527 Clinical (unspecified phase)
0.7126 Intermediate Similarity NPD7526 Approved
0.7126 Intermediate Similarity NPD52 Approved
0.7101 Intermediate Similarity NPD3455 Phase 2
0.7101 Intermediate Similarity NPD4005 Discontinued
0.7099 Intermediate Similarity NPD2161 Phase 2
0.709 Intermediate Similarity NPD7565 Approved
0.7055 Intermediate Similarity NPD1375 Discontinued
0.7055 Intermediate Similarity NPD7266 Discontinued
0.7039 Intermediate Similarity NPD8470 Clinical (unspecified phase)
0.7033 Intermediate Similarity NPD7311 Approved
0.7033 Intermediate Similarity NPD7313 Approved
0.7033 Intermediate Similarity NPD7312 Approved
0.7033 Intermediate Similarity NPD7310 Approved
0.7031 Intermediate Similarity NPD7497 Discontinued
0.7029 Intermediate Similarity NPD6746 Phase 2
0.7025 Intermediate Similarity NPD3136 Phase 2
0.7011 Intermediate Similarity NPD4663 Approved
0.7006 Intermediate Similarity NPD2970 Approved
0.7006 Intermediate Similarity NPD2969 Approved
0.7 Intermediate Similarity NPD7237 Clinical (unspecified phase)
0.7 Intermediate Similarity NPD5557 Phase 1
0.6995 Remote Similarity NPD7309 Approved
0.6983 Remote Similarity NPD3909 Discontinued
0.6973 Remote Similarity NPD7906 Approved
0.6973 Remote Similarity NPD6841 Approved
0.6973 Remote Similarity NPD6843 Phase 3
0.6973 Remote Similarity NPD6842 Approved
0.6966 Remote Similarity NPD2489 Approved
0.6966 Remote Similarity NPD27 Approved
0.6966 Remote Similarity NPD4481 Phase 3
0.6964 Remote Similarity NPD3536 Discontinued
0.6961 Remote Similarity NPD7007 Discovery
0.6951 Remote Similarity NPD7978 Discontinued
0.6951 Remote Similarity NPD2029 Clinical (unspecified phase)
0.6949 Remote Similarity NPD3051 Approved
0.694 Remote Similarity NPD4578 Approved
0.694 Remote Similarity NPD4577 Approved
0.694 Remote Similarity NPD5035 Approved
0.6937 Remote Similarity NPD5729 Clinical (unspecified phase)
0.6935 Remote Similarity NPD8360 Approved
0.6935 Remote Similarity NPD8361 Approved
0.6928 Remote Similarity NPD6331 Phase 2
0.6919 Remote Similarity NPD5090 Approved
0.6919 Remote Similarity NPD7615 Clinical (unspecified phase)
0.6919 Remote Similarity NPD5089 Approved
0.6909 Remote Similarity NPD7596 Clinical (unspecified phase)
0.6905 Remote Similarity NPD4357 Discontinued
0.6902 Remote Similarity NPD8407 Phase 2
0.6895 Remote Similarity NPD8485 Approved
0.6885 Remote Similarity NPD7549 Discontinued
0.6879 Remote Similarity NPD4433 Discontinued
0.6879 Remote Similarity NPD4104 Clinical (unspecified phase)
0.6879 Remote Similarity NPD4103 Phase 2
0.6868 Remote Similarity NPD3823 Discontinued
0.6866 Remote Similarity NPD8404 Phase 2
0.6864 Remote Similarity NPD4160 Clinical (unspecified phase)
0.6848 Remote Similarity NPD5763 Approved
0.6848 Remote Similarity NPD5762 Approved
0.6845 Remote Similarity NPD8435 Approved
0.6839 Remote Similarity NPD7972 Discontinued
0.6832 Remote Similarity NPD6405 Approved
0.6832 Remote Similarity NPD6407 Approved
0.6831 Remote Similarity NPD8368 Discontinued
0.6829 Remote Similarity NPD1753 Discontinued
0.6828 Remote Similarity NPD8150 Discontinued
0.6828 Remote Similarity NPD5037 Approved
0.6828 Remote Similarity NPD8424 Clinical (unspecified phase)
0.6828 Remote Similarity NPD5038 Approved
0.6821 Remote Similarity NPD8319 Approved
0.6821 Remote Similarity NPD6385 Approved
0.6821 Remote Similarity NPD6386 Approved
0.6821 Remote Similarity NPD8320 Phase 1
0.6818 Remote Similarity NPD7875 Clinical (unspecified phase)
0.6818 Remote Similarity NPD7874 Approved
0.681 Remote Similarity NPD2568 Approved
0.6804 Remote Similarity NPD6823 Phase 2
0.68 Remote Similarity NPD2229 Approved
0.68 Remote Similarity NPD2234 Approved
0.68 Remote Similarity NPD2228 Approved
0.6795 Remote Similarity NPD2230 Approved
0.6795 Remote Similarity NPD2233 Approved
0.6795 Remote Similarity NPD2232 Approved
0.679 Remote Similarity NPD6346 Approved
0.679 Remote Similarity NPD4060 Phase 1
0.6788 Remote Similarity NPD8486 Clinical (unspecified phase)
0.6788 Remote Similarity NPD9570 Approved
0.6786 Remote Similarity NPD6190 Approved
0.6784 Remote Similarity NPD7801 Approved
0.6774 Remote Similarity NPD5036 Approved
0.6768 Remote Similarity NPD3553 Approved
0.6768 Remote Similarity NPD3554 Approved
0.6768 Remote Similarity NPD3555 Approved
0.6768 Remote Similarity NPD3552 Approved
0.6766 Remote Similarity NPD4236 Phase 3
0.6766 Remote Similarity NPD4237 Approved
0.6765 Remote Similarity NPD7446 Clinical (unspecified phase)
0.6752 Remote Similarity NPD9622 Approved
0.6752 Remote Similarity NPD3676 Clinical (unspecified phase)
0.6752 Remote Similarity NPD4659 Approved
0.6744 Remote Similarity NPD3687 Approved
0.6744 Remote Similarity NPD3686 Approved
0.6743 Remote Similarity NPD2977 Approved
0.6743 Remote Similarity NPD2978 Approved
0.6743 Remote Similarity NPD5929 Approved
0.6728 Remote Similarity NPD2674 Phase 3
0.6727 Remote Similarity NPD4108 Discontinued
0.6726 Remote Similarity NPD6658 Clinical (unspecified phase)
0.6726 Remote Similarity NPD8166 Discontinued
0.6726 Remote Similarity NPD4628 Phase 3
0.6725 Remote Similarity NPD5261 Clinical (unspecified phase)
0.6723 Remote Similarity NPD4055 Discovery
0.672 Remote Similarity NPD7090 Clinical (unspecified phase)
0.671 Remote Similarity NPD5238 Clinical (unspecified phase)
0.671 Remote Similarity NPD2668 Approved
0.671 Remote Similarity NPD2667 Approved
0.6707 Remote Similarity NPD2157 Approved
0.6703 Remote Similarity NPD5026 Approved
0.6703 Remote Similarity NPD5028 Approved
0.6703 Remote Similarity NPD4955 Approved
0.6703 Remote Similarity NPD4954 Approved
0.6703 Remote Similarity NPD5034 Approved
0.6703 Remote Similarity NPD5032 Approved
0.6703 Remote Similarity NPD4419 Clinical (unspecified phase)
0.6703 Remote Similarity NPD36 Approved
0.6687 Remote Similarity NPD5736 Approved
0.6686 Remote Similarity NPD3692 Discontinued
0.6686 Remote Similarity NPD2677 Approved
0.6685 Remote Similarity NPD7959 Clinical (unspecified phase)
0.6683 Remote Similarity NPD8151 Discontinued
0.6667 Remote Similarity NPD6502 Phase 2
0.6667 Remote Similarity NPD3094 Phase 2
0.6667 Remote Similarity NPD3144 Approved
0.6667 Remote Similarity NPD42 Phase 2
0.6667 Remote Similarity NPD681 Clinical (unspecified phase)
0.6667 Remote Similarity NPD6042 Phase 2
0.6667 Remote Similarity NPD4678 Approved
0.6667 Remote Similarity NPD7827 Phase 1
0.6667 Remote Similarity NPD3145 Approved
0.6667 Remote Similarity NPD4675 Approved
0.6667 Remote Similarity NPD4123 Phase 3
0.6667 Remote Similarity NPD2494 Approved
0.6667 Remote Similarity NPD2493 Approved
0.6667 Remote Similarity NPD5617 Suspended
0.665 Remote Similarity NPD7047 Phase 3
0.665 Remote Similarity NPD4582 Approved
0.665 Remote Similarity NPD4583 Approved
0.6649 Remote Similarity NPD7038 Approved
0.6649 Remote Similarity NPD7039 Approved
0.6649 Remote Similarity NPD5039 Approved
0.6649 Remote Similarity NPD8014 Clinical (unspecified phase)
0.6649 Remote Similarity NPD5030 Phase 2
0.6648 Remote Similarity NPD7089 Clinical (unspecified phase)
0.6647 Remote Similarity NPD3656 Approved
0.6646 Remote Similarity NPD555 Phase 2
0.6646 Remote Similarity NPD1669 Approved
0.663 Remote Similarity NPD4956 Approved
0.6629 Remote Similarity NPD3453 Discontinued
0.6628 Remote Similarity NPD2675 Approved
0.6628 Remote Similarity NPD2676 Approved
0.6626 Remote Similarity NPD839 Approved
0.6626 Remote Similarity NPD1132 Approved
0.6626 Remote Similarity NPD1136 Approved
0.6626 Remote Similarity NPD1130 Approved
0.6626 Remote Similarity NPD7477 Discontinued
0.6626 Remote Similarity NPD840 Approved
0.6625 Remote Similarity NPD2194 Approved
0.6625 Remote Similarity NPD2195 Approved
0.6624 Remote Similarity NPD5350 Clinical (unspecified phase)
0.6624 Remote Similarity NPD5351 Clinical (unspecified phase)
0.6616 Remote Similarity NPD7999 Approved
0.6615 Remote Similarity NPD6535 Approved
0.6615 Remote Similarity NPD6534 Approved
0.6614 Remote Similarity NPD7243 Clinical (unspecified phase)
0.6612 Remote Similarity NPD7493 Clinical (unspecified phase)
0.6611 Remote Similarity NPD8127 Discontinued
0.661 Remote Similarity NPD2563 Approved
0.661 Remote Similarity NPD2560 Approved
0.6607 Remote Similarity NPD2424 Discontinued
0.6606 Remote Similarity NPD1772 Clinical (unspecified phase)
0.6606 Remote Similarity NPD4579 Clinical (unspecified phase)
0.6606 Remote Similarity NPD817 Approved
0.6606 Remote Similarity NPD823 Approved
0.6606 Remote Similarity NPD5314 Approved
0.6605 Remote Similarity NPD3027 Phase 3
0.6601 Remote Similarity NPD7930 Approved
0.6599 Remote Similarity NPD4002 Approved

Structure

External Identifiers

PubChem CID   21574192
ChEMBL   CHEMBL512971
ZINC  

Physicochemical Properties

Molecular Weight:  495.26
ALogP:  -1.302
MLogP:  3.88
XLogP:  4.431
# Rotatable Bonds:  8
Polar Surface Area:  119.58
# H-Bond Aceptor:  6
# H-Bond Donor:  4
# Rings:  4
# Heavy Atoms:  36

Download Data

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General Info & Identifiers & Properties  
Structure MOL file  
Source Organisms  
Biological Activities  
Similar NPs/Drugs