Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT139 | Cell Line | HT-29 | Homo sapiens | IC50 | = | 1.5 | nM | 18973388 |
NPT91 | Cell Line | KB | Homo sapiens | IC50 | = | 0.0003 | ug/ml | 19715342 |
NPT2657 | Cell Line | A10 | Rattus norvegicus | Activity | = | 80 | % | 19715342 |
NPT91 | Cell Line | KB | Homo sapiens | IC50 | = | 0.15 | nM | 25763602 |
NPT114 | Cell Line | LoVo | Homo sapiens | IC50 | = | 0.34 | nM | 25763602 |
NPT2657 | Cell Line | A10 | Rattus norvegicus | EC50 | = | 0.6 | nM | 25763602 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC106235 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
1.0 | High Similarity | NPC239660 |
0.8977 | High Similarity | NPC161143 |
0.8144 | Intermediate Similarity | NPC75498 |
0.7906 | Intermediate Similarity | NPC165538 |
0.7828 | Intermediate Similarity | NPC257511 |
0.7801 | Intermediate Similarity | NPC329961 |
0.7801 | Intermediate Similarity | NPC122427 |
0.7592 | Intermediate Similarity | NPC96016 |
0.7554 | Intermediate Similarity | NPC475920 |
0.7415 | Intermediate Similarity | NPC475350 |
0.7415 | Intermediate Similarity | NPC145178 |
0.7415 | Intermediate Similarity | NPC14877 |
0.7308 | Intermediate Similarity | NPC251036 |
0.7277 | Intermediate Similarity | NPC161242 |
0.7263 | Intermediate Similarity | NPC283783 |
0.7202 | Intermediate Similarity | NPC25316 |
0.7202 | Intermediate Similarity | NPC263485 |
0.7202 | Intermediate Similarity | NPC229160 |
0.7196 | Intermediate Similarity | NPC476103 |
0.7188 | Intermediate Similarity | NPC475534 |
0.7188 | Intermediate Similarity | NPC476080 |
0.715 | Intermediate Similarity | NPC475330 |
0.7143 | Intermediate Similarity | NPC24990 |
0.7136 | Intermediate Similarity | NPC475196 |
0.7113 | Intermediate Similarity | NPC174652 |
0.6983 | Remote Similarity | NPC476978 |
0.6949 | Remote Similarity | NPC89489 |
0.6914 | Remote Similarity | NPC287401 |
0.6908 | Remote Similarity | NPC475506 |
0.6875 | Remote Similarity | NPC155143 |
0.6852 | Remote Similarity | NPC79386 |
0.684 | Remote Similarity | NPC478158 |
0.6839 | Remote Similarity | NPC300315 |
0.6831 | Remote Similarity | NPC105717 |
0.6811 | Remote Similarity | NPC162104 |
0.6798 | Remote Similarity | NPC473763 |
0.6798 | Remote Similarity | NPC117244 |
0.6763 | Remote Similarity | NPC473640 |
0.6761 | Remote Similarity | NPC107077 |
0.6761 | Remote Similarity | NPC223791 |
0.6761 | Remote Similarity | NPC162860 |
0.6758 | Remote Similarity | NPC322878 |
0.6735 | Remote Similarity | NPC318930 |
0.6735 | Remote Similarity | NPC317362 |
0.6713 | Remote Similarity | NPC54744 |
0.6711 | Remote Similarity | NPC469858 |
0.6705 | Remote Similarity | NPC130309 |
0.6703 | Remote Similarity | NPC478251 |
0.6703 | Remote Similarity | NPC478252 |
0.6685 | Remote Similarity | NPC248283 |
0.6684 | Remote Similarity | NPC286551 |
0.6682 | Remote Similarity | NPC478157 |
0.6667 | Remote Similarity | NPC209509 |
0.6667 | Remote Similarity | NPC110602 |
0.6667 | Remote Similarity | NPC316008 |
0.6667 | Remote Similarity | NPC5620 |
0.6667 | Remote Similarity | NPC31385 |
0.6667 | Remote Similarity | NPC75726 |
0.6667 | Remote Similarity | NPC54420 |
0.6667 | Remote Similarity | NPC313867 |
0.6652 | Remote Similarity | NPC63279 |
0.665 | Remote Similarity | NPC326407 |
0.665 | Remote Similarity | NPC317725 |
0.6648 | Remote Similarity | NPC161069 |
0.663 | Remote Similarity | NPC314358 |
0.663 | Remote Similarity | NPC262077 |
0.6623 | Remote Similarity | NPC297642 |
0.6622 | Remote Similarity | NPC253987 |
0.6621 | Remote Similarity | NPC238945 |
0.662 | Remote Similarity | NPC320968 |
0.6618 | Remote Similarity | NPC213629 |
0.6613 | Remote Similarity | NPC2501 |
0.6612 | Remote Similarity | NPC314388 |
0.6612 | Remote Similarity | NPC315283 |
0.6611 | Remote Similarity | NPC471265 |
0.6611 | Remote Similarity | NPC471264 |
0.6609 | Remote Similarity | NPC478029 |
0.6596 | Remote Similarity | NPC122590 |
0.6593 | Remote Similarity | NPC269398 |
0.6593 | Remote Similarity | NPC263493 |
0.659 | Remote Similarity | NPC6975 |
0.659 | Remote Similarity | NPC46427 |
0.6575 | Remote Similarity | NPC98424 |
0.6575 | Remote Similarity | NPC476133 |
0.6575 | Remote Similarity | NPC470884 |
0.6575 | Remote Similarity | NPC92784 |
0.6575 | Remote Similarity | NPC178662 |
0.6571 | Remote Similarity | NPC100321 |
0.6571 | Remote Similarity | NPC293917 |
0.6566 | Remote Similarity | NPC477462 |
0.6559 | Remote Similarity | NPC240848 |
0.6554 | Remote Similarity | NPC200589 |
0.6532 | Remote Similarity | NPC252878 |
0.6524 | Remote Similarity | NPC171317 |
0.6524 | Remote Similarity | NPC129666 |
0.6522 | Remote Similarity | NPC478028 |
0.6516 | Remote Similarity | NPC281049 |
0.6514 | Remote Similarity | NPC75634 |
0.6512 | Remote Similarity | NPC200964 |
0.6505 | Remote Similarity | NPC138775 |
0.6488 | Remote Similarity | NPC4910 |
0.6486 | Remote Similarity | NPC471680 |
0.6474 | Remote Similarity | NPC202521 |
0.6459 | Remote Similarity | NPC294693 |
0.6458 | Remote Similarity | NPC297145 |
0.6458 | Remote Similarity | NPC197743 |
0.6452 | Remote Similarity | NPC475390 |
0.6441 | Remote Similarity | NPC319766 |
0.6441 | Remote Similarity | NPC275393 |
0.6432 | Remote Similarity | NPC52748 |
0.6425 | Remote Similarity | NPC255447 |
0.6419 | Remote Similarity | NPC473376 |
0.6418 | Remote Similarity | NPC64436 |
0.6416 | Remote Similarity | NPC476990 |
0.6416 | Remote Similarity | NPC19170 |
0.6398 | Remote Similarity | NPC315266 |
0.6391 | Remote Similarity | NPC165743 |
0.6359 | Remote Similarity | NPC163392 |
0.6359 | Remote Similarity | NPC239762 |
0.6348 | Remote Similarity | NPC475969 |
0.6348 | Remote Similarity | NPC474877 |
0.6348 | Remote Similarity | NPC475859 |
0.634 | Remote Similarity | NPC469898 |
0.6339 | Remote Similarity | NPC315804 |
0.6339 | Remote Similarity | NPC313804 |
0.6332 | Remote Similarity | NPC297862 |
0.633 | Remote Similarity | NPC225648 |
0.633 | Remote Similarity | NPC145113 |
0.633 | Remote Similarity | NPC329761 |
0.6329 | Remote Similarity | NPC329731 |
0.6329 | Remote Similarity | NPC17059 |
0.6326 | Remote Similarity | NPC476874 |
0.6318 | Remote Similarity | NPC469938 |
0.6316 | Remote Similarity | NPC475168 |
0.6316 | Remote Similarity | NPC7817 |
0.6313 | Remote Similarity | NPC473322 |
0.6311 | Remote Similarity | NPC49051 |
0.6308 | Remote Similarity | NPC469901 |
0.6304 | Remote Similarity | NPC470730 |
0.6304 | Remote Similarity | NPC477175 |
0.6304 | Remote Similarity | NPC470729 |
0.6304 | Remote Similarity | NPC477176 |
0.63 | Remote Similarity | NPC64216 |
0.6296 | Remote Similarity | NPC143325 |
0.6296 | Remote Similarity | NPC471821 |
0.6296 | Remote Similarity | NPC471820 |
0.6293 | Remote Similarity | NPC220852 |
0.629 | Remote Similarity | NPC139326 |
0.6281 | Remote Similarity | NPC473000 |
0.628 | Remote Similarity | NPC94752 |
0.6277 | Remote Similarity | NPC477177 |
0.627 | Remote Similarity | NPC268841 |
0.627 | Remote Similarity | NPC46098 |
0.627 | Remote Similarity | NPC307357 |
0.6269 | Remote Similarity | NPC469903 |
0.625 | Remote Similarity | NPC89987 |
0.6244 | Remote Similarity | NPC471052 |
0.6244 | Remote Similarity | NPC471051 |
0.6244 | Remote Similarity | NPC471053 |
0.623 | Remote Similarity | NPC478253 |
0.623 | Remote Similarity | NPC141050 |
0.623 | Remote Similarity | NPC478254 |
0.6226 | Remote Similarity | NPC184933 |
0.6226 | Remote Similarity | NPC59827 |
0.6222 | Remote Similarity | NPC477714 |
0.6222 | Remote Similarity | NPC111428 |
0.6218 | Remote Similarity | NPC470902 |
0.6215 | Remote Similarity | NPC175726 |
0.6215 | Remote Similarity | NPC474082 |
0.6213 | Remote Similarity | NPC285343 |
0.6207 | Remote Similarity | NPC470546 |
0.6207 | Remote Similarity | NPC469900 |
0.6203 | Remote Similarity | NPC176226 |
0.6193 | Remote Similarity | NPC73655 |
0.6185 | Remote Similarity | NPC263117 |
0.6185 | Remote Similarity | NPC242872 |
0.6185 | Remote Similarity | NPC125181 |
0.6184 | Remote Similarity | NPC228835 |
0.6183 | Remote Similarity | NPC476259 |
0.6181 | Remote Similarity | NPC254700 |
0.6174 | Remote Similarity | NPC24370 |
0.6174 | Remote Similarity | NPC319232 |
0.6166 | Remote Similarity | NPC202198 |
0.6166 | Remote Similarity | NPC262166 |
0.6158 | Remote Similarity | NPC136797 |
0.615 | Remote Similarity | NPC469427 |
0.615 | Remote Similarity | NPC49195 |
0.615 | Remote Similarity | NPC469426 |
0.6149 | Remote Similarity | NPC470545 |
0.6145 | Remote Similarity | NPC101719 |
0.6142 | Remote Similarity | NPC473003 |
0.6142 | Remote Similarity | NPC469902 |
0.614 | Remote Similarity | NPC477527 |
0.614 | Remote Similarity | NPC149708 |
0.6139 | Remote Similarity | NPC328494 |
0.6134 | Remote Similarity | NPC473002 |
0.6129 | Remote Similarity | NPC54537 |
0.612 | Remote Similarity | NPC314056 |
0.6117 | Remote Similarity | NPC197682 |
0.6117 | Remote Similarity | NPC77905 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC106235 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
1.0 | High Similarity | NPD8339 | Clinical (unspecified phase) |
0.7989 | Intermediate Similarity | NPD6348 | Clinical (unspecified phase) |
0.7937 | Intermediate Similarity | NPD6349 | Phase 1 |
0.7402 | Intermediate Similarity | NPD8071 | Approved |
0.7396 | Intermediate Similarity | NPD7977 | Clinical (unspecified phase) |
0.7384 | Intermediate Similarity | NPD8172 | Phase 2 |
0.7384 | Intermediate Similarity | NPD8173 | Phase 2 |
0.7333 | Intermediate Similarity | NPD6632 | Clinical (unspecified phase) |
0.7198 | Intermediate Similarity | NPD8260 | Approved |
0.7143 | Intermediate Similarity | NPD6092 | Discontinued |
0.7136 | Intermediate Similarity | NPD4949 | Discontinued |
0.7064 | Intermediate Similarity | NPD7711 | Discontinued |
0.7039 | Intermediate Similarity | NPD7321 | Clinical (unspecified phase) |
0.6971 | Remote Similarity | NPD8272 | Phase 2 |
0.6798 | Remote Similarity | NPD2893 | Phase 3 |
0.678 | Remote Similarity | NPD7944 | Discontinued |
0.6743 | Remote Similarity | NPD4125 | Approved |
0.6653 | Remote Similarity | NPD6627 | Discontinued |
0.6648 | Remote Similarity | NPD7113 | Clinical (unspecified phase) |
0.6639 | Remote Similarity | NPD5461 | Discontinued |
0.6607 | Remote Similarity | NPD8075 | Discontinued |
0.659 | Remote Similarity | NPD7195 | Clinical (unspecified phase) |
0.6579 | Remote Similarity | NPD6915 | Approved |
0.6571 | Remote Similarity | NPD7621 | Clinical (unspecified phase) |
0.6522 | Remote Similarity | NPD2437 | Approved |
0.6522 | Remote Similarity | NPD2436 | Approved |
0.6517 | Remote Similarity | NPD7104 | Clinical (unspecified phase) |
0.6495 | Remote Similarity | NPD8169 | Discontinued |
0.6479 | Remote Similarity | NPD4134 | Clinical (unspecified phase) |
0.6455 | Remote Similarity | NPD7971 | Clinical (unspecified phase) |
0.6455 | Remote Similarity | NPD5638 | Approved |
0.6455 | Remote Similarity | NPD7970 | Approved |
0.6444 | Remote Similarity | NPD6173 | Approved |
0.6443 | Remote Similarity | NPD2511 | Approved |
0.6419 | Remote Similarity | NPD7712 | Clinical (unspecified phase) |
0.6402 | Remote Similarity | NPD1004 | Phase 2 |
0.6402 | Remote Similarity | NPD1005 | Phase 2 |
0.6398 | Remote Similarity | NPD5265 | Approved |
0.6398 | Remote Similarity | NPD5264 | Approved |
0.6396 | Remote Similarity | NPD4174 | Clinical (unspecified phase) |
0.6396 | Remote Similarity | NPD8000 | Clinical (unspecified phase) |
0.6396 | Remote Similarity | NPD8271 | Discontinued |
0.6392 | Remote Similarity | NPD4557 | Approved |
0.6389 | Remote Similarity | NPD7001 | Phase 3 |
0.6382 | Remote Similarity | NPD8284 | Discontinued |
0.635 | Remote Similarity | NPD7965 | Phase 2 |
0.635 | Remote Similarity | NPD8124 | Phase 3 |
0.635 | Remote Similarity | NPD7964 | Clinical (unspecified phase) |
0.635 | Remote Similarity | NPD8126 | Clinical (unspecified phase) |
0.6349 | Remote Similarity | NPD7892 | Clinical (unspecified phase) |
0.6296 | Remote Similarity | NPD8072 | Approved |
0.6292 | Remote Similarity | NPD2585 | Clinical (unspecified phase) |
0.6291 | Remote Similarity | NPD3469 | Phase 3 |
0.6289 | Remote Similarity | NPD7749 | Clinical (unspecified phase) |
0.6287 | Remote Similarity | NPD6044 | Discontinued |
0.6286 | Remote Similarity | NPD6665 | Discontinued |
0.6284 | Remote Similarity | NPD8493 | Clinical (unspecified phase) |
0.6273 | Remote Similarity | NPD7809 | Clinical (unspecified phase) |
0.6269 | Remote Similarity | NPD5189 | Clinical (unspecified phase) |
0.6244 | Remote Similarity | NPD7470 | Discontinued |
0.6243 | Remote Similarity | NPD8323 | Discontinued |
0.6238 | Remote Similarity | NPD6659 | Phase 2 |
0.6238 | Remote Similarity | NPD1977 | Clinical (unspecified phase) |
0.623 | Remote Similarity | NPD5323 | Approved |
0.622 | Remote Similarity | NPD8110 | Clinical (unspecified phase) |
0.6216 | Remote Similarity | NPD4126 | Approved |
0.6215 | Remote Similarity | NPD2584 | Suspended |
0.6214 | Remote Similarity | NPD8069 | Phase 3 |
0.621 | Remote Similarity | NPD7834 | Approved |
0.6209 | Remote Similarity | NPD3288 | Approved |
0.6205 | Remote Similarity | NPD5634 | Approved |
0.6204 | Remote Similarity | NPD7903 | Clinical (unspecified phase) |
0.6203 | Remote Similarity | NPD2022 | Approved |
0.6203 | Remote Similarity | NPD7816 | Clinical (unspecified phase) |
0.6199 | Remote Similarity | NPD8261 | Discontinued |
0.6183 | Remote Similarity | NPD3480 | Approved |
0.6182 | Remote Similarity | NPD7981 | Discontinued |
0.6175 | Remote Similarity | NPD8073 | Approved |
0.6172 | Remote Similarity | NPD6891 | Phase 2 |
0.6161 | Remote Similarity | NPD5077 | Approved |
0.6161 | Remote Similarity | NPD5076 | Approved |
0.6158 | Remote Similarity | NPD2055 | Phase 3 |
0.6158 | Remote Similarity | NPD2054 | Approved |
0.6154 | Remote Similarity | NPD2044 | Approved |
0.6154 | Remote Similarity | NPD2049 | Clinical (unspecified phase) |
0.6154 | Remote Similarity | NPD2050 | Clinical (unspecified phase) |
0.6154 | Remote Similarity | NPD2048 | Approved |
0.6154 | Remote Similarity | NPD2045 | Approved |
0.6154 | Remote Similarity | NPD2051 | Approved |
0.6154 | Remote Similarity | NPD2047 | Approved |
0.6154 | Remote Similarity | NPD2043 | Approved |
0.6154 | Remote Similarity | NPD21 | Approved |
0.6154 | Remote Similarity | NPD2046 | Approved |
0.615 | Remote Similarity | NPD4508 | Discontinued |
0.6146 | Remote Similarity | NPD6368 | Clinical (unspecified phase) |
0.6146 | Remote Similarity | NPD2957 | Phase 2 |
0.6143 | Remote Similarity | NPD2015 | Discontinued |
0.6141 | Remote Similarity | NPD8416 | Discontinued |
0.6138 | Remote Similarity | NPD6860 | Clinical (unspecified phase) |
0.6134 | Remote Similarity | NPD4648 | Approved |
0.6134 | Remote Similarity | NPD4647 | Approved |
0.6134 | Remote Similarity | NPD4646 | Approved |
0.6133 | Remote Similarity | NPD7496 | Phase 2 |
0.6128 | Remote Similarity | NPD7807 | Clinical (unspecified phase) |
0.6122 | Remote Similarity | NPD7118 | Clinical (unspecified phase) |
0.6121 | Remote Similarity | NPD6347 | Phase 2 |
0.6121 | Remote Similarity | NPD7818 | Clinical (unspecified phase) |
0.612 | Remote Similarity | NPD5299 | Approved |
0.6117 | Remote Similarity | NPD2088 | Approved |
0.6117 | Remote Similarity | NPD2087 | Approved |
0.6114 | Remote Similarity | NPD5230 | Approved |
0.6114 | Remote Similarity | NPD8356 | Approved |
0.6114 | Remote Similarity | NPD5229 | Approved |
0.6111 | Remote Similarity | NPD5665 | Clinical (unspecified phase) |
0.6111 | Remote Similarity | NPD8119 | Discontinued |
0.6111 | Remote Similarity | NPD6137 | Clinical (unspecified phase) |
0.6111 | Remote Similarity | NPD6857 | Phase 3 |
0.6108 | Remote Similarity | NPD8643 | Discontinued |
0.6106 | Remote Similarity | NPD7482 | Phase 2 |
0.6106 | Remote Similarity | NPD2787 | Clinical (unspecified phase) |
0.6106 | Remote Similarity | NPD7483 | Phase 2 |
0.6103 | Remote Similarity | NPD2717 | Phase 2 |
0.6099 | Remote Similarity | NPD8013 | Clinical (unspecified phase) |
0.6094 | Remote Similarity | NPD3988 | Approved |
0.6094 | Remote Similarity | NPD3987 | Approved |
0.6091 | Remote Similarity | NPD6732 | Clinical (unspecified phase) |
0.6087 | Remote Similarity | NPD3561 | Clinical (unspecified phase) |
0.6085 | Remote Similarity | NPD7791 | Approved |
0.6085 | Remote Similarity | NPD7950 | Approved |
0.6085 | Remote Similarity | NPD7790 | Approved |
0.6085 | Remote Similarity | NPD7953 | Approved |
0.6085 | Remote Similarity | NPD7951 | Approved |
0.6085 | Remote Similarity | NPD7789 | Approved |
0.6085 | Remote Similarity | NPD7952 | Approved |
0.6078 | Remote Similarity | NPD7730 | Approved |
0.6078 | Remote Similarity | NPD7731 | Approved |
0.6077 | Remote Similarity | NPD5339 | Clinical (unspecified phase) |
0.6077 | Remote Similarity | NPD3608 | Clinical (unspecified phase) |
0.6073 | Remote Similarity | NPD6552 | Clinical (unspecified phase) |
0.6058 | Remote Similarity | NPD1745 | Approved |
0.6052 | Remote Similarity | NPD7781 | Approved |
0.6052 | Remote Similarity | NPD7780 | Approved |
0.6045 | Remote Similarity | NPD4903 | Approved |
0.6045 | Remote Similarity | NPD4906 | Approved |
0.6045 | Remote Similarity | NPD4905 | Approved |
0.6043 | Remote Similarity | NPD2321 | Approved |
0.604 | Remote Similarity | NPD6303 | Approved |
0.604 | Remote Similarity | NPD6304 | Approved |
0.6037 | Remote Similarity | NPD7049 | Clinical (unspecified phase) |
0.6035 | Remote Similarity | NPD8406 | Clinical (unspecified phase) |
0.6035 | Remote Similarity | NPD5523 | Approved |
0.6035 | Remote Similarity | NPD5524 | Approved |
0.6026 | Remote Similarity | NPD7824 | Approved |
0.6021 | Remote Similarity | NPD5298 | Clinical (unspecified phase) |
0.6019 | Remote Similarity | NPD3449 | Discontinued |
0.6019 | Remote Similarity | NPD8021 | Approved |
0.6019 | Remote Similarity | NPD8103 | Clinical (unspecified phase) |
0.6019 | Remote Similarity | NPD7490 | Discontinued |
0.6019 | Remote Similarity | NPD8020 | Approved |
0.6018 | Remote Similarity | NPD4904 | Approved |
0.6018 | Remote Similarity | NPD7289 | Clinical (unspecified phase) |
0.6011 | Remote Similarity | NPD7728 | Clinical (unspecified phase) |
0.601 | Remote Similarity | NPD5613 | Approved |
0.601 | Remote Similarity | NPD5614 | Approved |
0.601 | Remote Similarity | NPD963 | Discontinued |
0.6009 | Remote Similarity | NPD8430 | Approved |
0.6009 | Remote Similarity | NPD8405 | Clinical (unspecified phase) |
0.6008 | Remote Similarity | NPD6205 | Discontinued |
0.6 | Remote Similarity | NPD6888 | Discontinued |
0.6 | Remote Similarity | NPD5322 | Clinical (unspecified phase) |
0.6 | Remote Similarity | NPD5341 | Clinical (unspecified phase) |
0.6 | Remote Similarity | NPD7594 | Clinical (unspecified phase) |
0.5992 | Remote Similarity | NPD8247 | Approved |
0.5992 | Remote Similarity | NPD8246 | Approved |
0.5991 | Remote Similarity | NPD7271 | Approved |
0.599 | Remote Similarity | NPD5636 | Discontinued |
0.5989 | Remote Similarity | NPD1646 | Approved |
0.5989 | Remote Similarity | NPD5004 | Approved |
0.5985 | Remote Similarity | NPD8107 | Approved |
0.598 | Remote Similarity | NPD4567 | Approved |
0.598 | Remote Similarity | NPD4566 | Approved |
0.5974 | Remote Similarity | NPD6718 | Discontinued |
0.5968 | Remote Similarity | NPD8265 | Approved |
0.5965 | Remote Similarity | NPD5818 | Discontinued |
0.5964 | Remote Similarity | NPD7665 | Phase 2 |
0.5964 | Remote Similarity | NPD7666 | Phase 3 |
0.5963 | Remote Similarity | NPD7000 | Clinical (unspecified phase) |
0.5963 | Remote Similarity | NPD6999 | Discontinued |
0.5961 | Remote Similarity | NPD6916 | Clinical (unspecified phase) |
0.596 | Remote Similarity | NPD5867 | Clinical (unspecified phase) |
0.5957 | Remote Similarity | NPD8374 | Phase 3 |
0.5952 | Remote Similarity | NPD2091 | Phase 2 |
0.5952 | Remote Similarity | NPD2096 | Phase 2 |
0.5951 | Remote Similarity | NPD750 | Phase 2 |
0.5949 | Remote Similarity | NPD7613 | Discontinued |
0.5949 | Remote Similarity | NPD3575 | Approved |
0.5949 | Remote Similarity | NPD3576 | Approved |
0.5946 | Remote Similarity | NPD2849 | Clinical (unspecified phase) |
0.5942 | Remote Similarity | NPD5755 | Clinical (unspecified phase) |
0.594 | Remote Similarity | NPD7826 | Clinical (unspecified phase) |
PubChem CID   | 10887298 |
ChEMBL   | CHEMBL501233 |
ZINC   |
Molecular Weight:   | 798.51 |
ALogP:   | -1.1101 |
MLogP:   | 4.76 |
XLogP:   | 7.472 |
# Rotatable Bonds:   | 38 |
Polar Surface Area:   | 168.63 |
# H-Bond Aceptor:   | 12 |
# H-Bond Donor:   | 2 |
# Rings:   | 3 |
# Heavy Atoms:   | 56 |