Plant ID: NPO9469
Plant Latin Name: Digitalis obscura
Taxonomy Genus: Digitalis
Taxonomy Family: Plantaginaceae
NCBI TaxonomyDB:
202408
Plant-of-the-World-Online:
n.a.
NR1H4; |
Cytochrome P450 Enzymes: |
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Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|
Nuclear hormone receptor subfamily 1 group H | NR1H4 | Bile acid receptor FXR | Q96RI1 | CHEMBL2047 |
GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|
MF | GO:0060089; molecular transducer activity | GO:0038181; bile acid receptor activity | 1.553E-04 | 1.537E-01 | NR1H4 |
MF | GO:0060089; molecular transducer activity | GO:0004887; thyroid hormone receptor activity | 3.624E-04 | 2.546E-01 | NR1H4 |
MF | GO:0005488; binding | GO:0046965; retinoid X receptor binding | 7.766E-04 | 3.676E-01 | NR1H4 |
MF | GO:0005488; binding | GO:0016922; ligand-dependent nuclear receptor binding | 1.087E-03 | 4.227E-01 | NR1H4 |
Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|---|
09150 Organismal Systems | 09154 Digestive system | hsa04976 | Bile secretion | 3.550E-03 | 3.550E-03 | NR1H4 |
ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
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