Plant Name: Symplocos chinensis
Taxonomic Information:
Plant ID: NPO8121
Plant Latin Name: Symplocos chinensis
Taxonomy Genus: Symplocos
Taxonomy Family: Symplocaceae
Plant External Links:
NCBI TaxonomyDB:
167894
Plant-of-the-World-Online:
n.a.
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Collective Molecular Activities of the Plant
List of Human Proteins Collectively Targeted by the Plant
Click Gene ID to Access Activity Profile of Individual Target
| MAPT; |
List of Human Cytochrome P450 Enzymes Affected by the Plant
Click Gene ID to Access Activity Profile of Individual Enzyme
| Cytochrome P450 Enzymes: |
|---|
Detailed Information of Target Proteins
| Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|
| Unclassified | MAPT | Microtubule-associated protein tau | P10636 | CHEMBL1293224 |
Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)
Detailed Information of Enriched Gene Ontolgy
| GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|
| BP | GO:0009987; cellular process | GO:1990000; amyloid fibril formation | 4.142E-04 | 5.340E-01 | MAPT |
| BP | GO:0009987; cellular process | GO:0019896; axonal transport of mitochondrion | 4.659E-04 | 5.340E-01 | MAPT |
| MF | GO:0005488; binding | GO:0034452; dynactin binding | 5.695E-04 | 5.905E-01 | MAPT |
| CC | GO:0044464; cell part | GO:0030673; axolemma | 8.283E-04 | 6.997E-01 | MAPT |
| MF | GO:0005488; binding | GO:0034185; apolipoprotein binding | 8.283E-04 | 6.997E-01 | MAPT |
| MF | GO:0005488; binding | GO:0051721; protein phosphatase 2A binding | 1.450E-03 | 8.306E-01 | MAPT |
| MF | GO:0005488; binding | GO:0051879; Hsp90 protein binding | 1.657E-03 | 9.018E-01 | MAPT |
| CC | GO:0044464; cell part | GO:0032838; plasma membrane bounded cell projection cytoplasm | 3.469E-03 | 1.000E+00 | MAPT |
| MF | GO:0005488; binding | GO:0042803; protein homodimerization activity | 4.116E-02 | 1.000E+00 | MAPT |
Enriched KEGG Pathways of Target Proteins (Activity≤10μM)
Top 10 KEGG Pathways (ordered by adjusted p-value)
Detailed Information of Enriched KEGG Pathways
| Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|---|
| 09160 Human Diseases | 09163 Neurodegenerative diseases | hsa05010 | Alzheimer's disease | 8.400E-03 | 1.275E-02 | MAPT |
| 09130 Environmental Information Processing | 09132 Signal transduction | hsa04010 | MAPK signaling pathway | 1.275E-02 | 1.275E-02 | MAPT |
Human Diseases Associated with the Target Proteins of the Plant
Detailed Information of Human Diseases
| ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
|---|
>> Profiles of ingredients and activity landscape
>> Targets derived from weak experimental activities
