Plant ID: NPO7081
Plant Latin Name: Sidastrum tehuacanum
Taxonomy Genus: Sidastrum
Taxonomy Family: Malvaceae
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
235982-2
Unknown.
Mexico
NOX4; HSD17B10; POLB; APEX1; | |
PLG; | |
HTT; |
Cytochrome P450 Enzymes: |
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Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|
Enzyme_unclassified | NOX4 | NADPH oxidase 4 | Q9NPH5 | CHEMBL1250375 |
Enzyme_unclassified | HSD17B10 | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Q99714 | CHEMBL4159 |
Enzyme_unclassified | POLB | DNA polymerase beta | P06746 | CHEMBL2392 |
Enzyme_unclassified | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | P27695 | CHEMBL5619 |
Serine protease | PLG | Plasminogen | P00747 | CHEMBL1801 |
Unclassified | HTT | Huntingtin | P42858 | CHEMBL5514 |
GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|
BP | GO:0009987; cellular process | GO:0006286; base-excision repair, base-free sugar-phosphate removal | 8.041E-08 | 1.751E-03 | APEX1, POLB |
MF | Unclassified; | GO:0003906; DNA-(apurinic or apyrimidinic site) lyase activity | 6.262E-06 | 3.409E-02 | APEX1, POLB |
BP | GO:0032502; developmental process | GO:0007568; aging | 3.288E-05 | 1.265E-01 | APEX1, NOX4, POLB |
BP | GO:0050896; response to stimulus | GO:0071320; cellular response to cAMP | 9.785E-05 | 3.044E-01 | APEX1, NOX4 |
BP | GO:0050896; response to stimulus | GO:0010332; response to gamma radiation | 1.142E-04 | 3.110E-01 | NOX4, POLB |
BP | GO:0040011; locomotion | GO:0014910; regulation of smooth muscle cell migration | 1.762E-04 | 3.382E-01 | APEX1, NOX4 |
MF | GO:0005488; binding | GO:0003684; damaged DNA binding | 1.762E-04 | 3.382E-01 | APEX1, POLB |
CC | GO:0044464; cell part | GO:0048471; perinuclear region of cytoplasm | 6.936E-04 | 5.034E-01 | APEX1, HTT, NOX4 |
CC | GO:0044464; cell part | GO:0005739; mitochondrion | 5.122E-03 | 9.533E-01 | APEX1, HSD17B10, NOX4 |
Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|---|
09120 Genetic Information Processing | 09124 Replication and repair | hsa03410 | Base excision repair | 3.944E-05 | 4.338E-04 | POLB, APEX1 |
09100 Metabolism | 09105 Amino acid metabolism | hsa00280 | Valine, leucine and isoleucine degradation | 1.432E-02 | 6.118E-02 | HSD17B10 |
09160 Human Diseases | 09167 Infectious diseases | hsa05150 | Staphylococcus aureus infection | 1.668E-02 | 6.118E-02 | PLG |
09150 Organismal Systems | 09151 Immune system | hsa04610 | Complement and coagulation cascades | 2.347E-02 | 6.454E-02 | PLG |
09160 Human Diseases | 09167 Infectious diseases | hsa05164 | Influenza A | 5.137E-02 | 8.244E-02 | PLG |
09160 Human Diseases | 09163 Neurodegenerative diseases | hsa05010 | Alzheimer's disease | 4.936E-02 | 8.244E-02 | HSD17B10 |
09160 Human Diseases | 09161 Cancers | hsa05203 | Viral carcinogenesis | 5.995E-02 | 8.244E-02 | POLB |
09160 Human Diseases | 09163 Neurodegenerative diseases | hsa05016 | Huntington's disease | 5.653E-02 | 8.244E-02 | HTT |
09160 Human Diseases | 09167 Infectious diseases | hsa05166 | HTLV-I infection | 7.496E-02 | 8.831E-02 | POLB |
09130 Environmental Information Processing | 09133 Signaling molecules and interaction | hsa04080 | Neuroactive ligand-receptor interaction | 8.028E-02 | 8.831E-02 | PLG |
ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
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