Plant ID: NPO6284
Plant Latin Name: Frasera caroliniensis
Taxonomy Genus: Frasera
Taxonomy Family: Gentianaceae
NCBI TaxonomyDB:
485363
Plant-of-the-World-Online:
367672-1
Unknown.
Canada; United States; Georgia
GPBAR1; | |
NR1H4; | |
AKR1B10; |
Cytochrome P450 Enzymes: |
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Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|
Enzyme_unclassified | AKR1B10 | Aldo-keto reductase family 1 member B10 | O60218 | CHEMBL5983 |
Nuclear hormone receptor subfamily 1 group H | NR1H4 | Bile acid receptor FXR | Q96RI1 | CHEMBL2047 |
Small molecule receptor (family A GPCR) | GPBAR1 | G-protein coupled bile acid receptor 1 | Q8TDU6 | CHEMBL5409 |
GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|
MF | GO:0003824; catalytic activity | GO:0001758; retinal dehydrogenase activity | 1.087E-03 | 5.504E-01 | AKR1B10 |
MF | GO:0060089; molecular transducer activity | GO:0004887; thyroid hormone receptor activity | 1.087E-03 | 5.504E-01 | NR1H4 |
MF | GO:0005488; binding | GO:0046965; retinoid X receptor binding | 2.328E-03 | 7.681E-01 | NR1H4 |
MF | GO:0005488; binding | GO:0016922; ligand-dependent nuclear receptor binding | 3.258E-03 | 9.096E-01 | NR1H4 |
CC | GO:0044464; cell part | GO:0005764; lysosome | 4.196E-02 | 1.000E+00 | AKR1B10 |
Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
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ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
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