CMAUP Plant Collective Molecular Activities

Plant Name: Baliospermum axillare

Taxonomic Information:

Plant ID: NPO5464
Plant Latin Name: Baliospermum axillare
Taxonomy Genus: Baliospermum
Taxonomy Family: Euphorbiaceae

Plant External Links:

NCBI TaxonomyDB: n.a.
Plant-of-the-World-Online: n.a.

Used in Medicines:

Country/Region:

India

Traditional Medicine System:

Sowa-Rigpa; Indian Folk; Unani; Ayurveda; Siddha

Geographical Distribution:

India

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Collective Molecular Activities of the Plant

List of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Target

Target Class	Target Proteins
Enzyme_unclassified	PTGES;

List of Human Cytochrome P450 Enzymes Affected by the Plant

Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Enzyme

Cytochrome P450 Enzymes:

Detailed Information of Target Proteins

Protein Class	Gene ID	Protein Name	Uniprot ID	Target ChEMBL ID
Enzyme_unclassified	PTGES	Prostaglandin E synthase	O14684	CHEMBL5658

Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)

Detailed Information of Enriched Gene Ontolgy

GO Type	GO Category	Enriched GO Terms	p-Value	Adjusted p-Value	Enriched Genes
BP	GO:0008152; metabolic process	GO:0019371; cyclooxygenase pathway	5.695E-04	1.000E+00	PTGES
BP	GO:0050896; response to stimulus	GO:0032496; response to lipopolysaccharide	1.434E-02	1.000E+00	PTGES
BP	GO:0050896; response to stimulus	GO:0034097; response to cytokine	2.475E-02	1.000E+00	PTGES
BP	GO:0008283; cell proliferation	GO:0008285; negative regulation of cell proliferation	3.645E-02	1.000E+00	PTGES
BP	GO:0050896; response to stimulus	GO:0014070; response to organic cyclic compound	3.764E-02	1.000E+00	PTGES
CC	GO:0044464; cell part	GO:0005641; nuclear envelope lumen	4.142E-04	1.000E+00	PTGES
CC	GO:0044464; cell part	GO:0048471; perinuclear region of cytoplasm	3.350E-02	1.000E+00	PTGES
CC	GO:0016020; membrane	GO:0005789; endoplasmic reticulum membrane	4.768E-02	1.000E+00	PTGES

Enriched KEGG Pathways of Target Proteins (Activity≤10μM)

Top 10 KEGG Pathways (ordered by adjusted p-value)

Detailed Information of Enriched KEGG Pathways

Pathway Category Top Level	Pathway Category Second Level	Pathway ID	Pathway Name	p-Value	Adjusted p-Value	Enriched Genes
09100 Metabolism	09103 Lipid metabolism	hsa00590	Arachidonic acid metabolism	3.100E-03	6.200E-03	PTGES
Unclassified	Unclassified	hsa01100	Metabolic pathways	6.195E-02	6.195E-02	PTGES

Human Diseases Associated with the Target Proteins of the Plant

Detailed Information of Human Diseases

ICD10 Disease Category	Disease Name	ICD10 Code	Associated Disease Targets (Association Ref: TTD database)

Data Section	Select to Download
1. General Info & Plant Usage & Geographical Distribution
2. Human Target Proteins
3. Target Gene Ontology
4. Target KEGG Pathway
5. Related Human Diseases