Plant Name: aglaonema treubii
Taxonomic Information:
Plant ID: NPO33446
Plant Latin Name: aglaonema treubii
Taxonomy Genus: Aglaonema
Taxonomy Family: Araceae
Plant External Links:
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
n.a.
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Collective Molecular Activities of the Plant
List of Human Proteins Collectively Targeted by the Plant
Click Gene ID to Access Activity Profile of Individual Target
List of Human Cytochrome P450 Enzymes Affected by the Plant
Click Gene ID to Access Activity Profile of Individual Enzyme
| Cytochrome P450 Enzymes: |
|---|
Detailed Information of Target Proteins
| Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|
| Enzyme_unclassified | GANC | Neutral alpha-glucosidase C | Q8TET4 | CHEMBL2520 |
| Enzyme_unclassified | SI | Sucrase-isomaltase | P14410 | CHEMBL2748 |
| Enzyme_unclassified | AGL | Glycogen debranching enzyme | P35573 | CHEMBL5272 |
| Hydrolase | GAA | Lysosomal alpha-glucosidase | P10253 | CHEMBL2608 |
| Hydrolase | MGAM | Maltase-glucoamylase | O43451 | CHEMBL2074 |
Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)
Detailed Information of Enriched Gene Ontolgy
| GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|
| BP | GO:0008152; metabolic process | GO:0000023; maltose metabolic process | 8.327E-12 | 3.022E-08 | GAA, GANC, MGAM |
| MF | GO:0003824; catalytic activity | GO:0032450; maltose alpha-glucosidase activity | 8.327E-12 | 3.022E-08 | GAA, GANC, MGAM |
| MF | GO:0003824; catalytic activity | GO:0004574; oligo-1,6-glucosidase activity | 5.361E-08 | 7.296E-05 | GAA, SI |
| BP | GO:0032501; multicellular organismal process | GO:0044245; polysaccharide digestion | 8.038E-07 | 7.955E-04 | MGAM, SI |
| MF | GO:0003824; catalytic activity | GO:0004558; alpha-1,4-glucosidase activity | 8.623E-16 | 6.259E-12 | GAA, GANC, MGAM, SI |
Enriched KEGG Pathways of Target Proteins (Activity≤10μM)
Top 10 KEGG Pathways (ordered by adjusted p-value)
Detailed Information of Enriched KEGG Pathways
| Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|---|
| 09100 Metabolism | 09101 Carbohydrate metabolism | hsa00500 | Starch and sucrose metabolism | 1.433E-13 | 7.166E-13 | MGAM, AGL, GAA, SI, GANC |
| 09100 Metabolism | 09101 Carbohydrate metabolism | hsa00052 | Galactose metabolism | 2.054E-11 | 5.135E-11 | MGAM, GAA, SI, GANC |
| Unclassified | Unclassified | hsa01100 | Metabolic pathways | 9.056E-07 | 1.509E-06 | MGAM, SI, GAA, AGL, GANC |
| 09150 Organismal Systems | 09154 Digestive system | hsa04973 | Carbohydrate digestion and absorption | 4.929E-05 | 6.161E-05 | MGAM, SI |
| 09140 Cellular Processes | 09141 Transport and catabolism | hsa04142 | Lysosome | 3.038E-02 | 3.038E-02 | GAA |
Human Diseases Associated with the Target Proteins of the Plant
Detailed Information of Human Diseases
| ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
|---|---|---|---|
| E00-E89: Endocrine, nutritional and metabolic diseases | Type 2 diabetes | E11 | MGAM; |
| A00-B99: Certain infectious and parasitic diseases | Dengue fever | A90 | MGAM; |
| E00-E89: Endocrine, nutritional and metabolic diseases | Diabetes | E23.2, N25.1 | MGAM; |
| I00-I99: Diseases of the circulatory system | Cardiovascular disorder | I00-I99 | MGAM; |
| M00-M99: Diseases of the musculoskeletal system and connective tissue | Muscle disease | M60-M63 | MGAM; |
| A00-B99: Certain infectious and parasitic diseases | Acquired immune deficiency syndrome | B20 | MGAM; |
| E00-E89: Endocrine, nutritional and metabolic diseases | Pompe's disease | E74.02 | MGAM; GAA; |
| R00-R99: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified | Hyperglycemia | R73.9 | MGAM; |
>> Profiles of ingredients and activity landscape
>> Targets derived from weak experimental activities
