Plant Name: arundina gramnifolia
Taxonomic Information:
Plant ID: NPO33109
Plant Latin Name: arundina gramnifolia
Taxonomy Genus: Arundina
Taxonomy Family: Orchidaceae
Plant External Links:
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
n.a.
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Collective Molecular Activities of the Plant
List of Human Proteins Collectively Targeted by the Plant
Click Gene ID to Access Activity Profile of Individual Target
List of Human Cytochrome P450 Enzymes Affected by the Plant
Click Gene ID to Access Activity Profile of Individual Enzyme
| Cytochrome P450 Enzymes: |
|---|
Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)
Detailed Information of Enriched Gene Ontolgy
| GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|
| BP | GO:0032501; multicellular organismal process | GO:1901898; negative regulation of relaxation of cardiac muscle | 1.608E-08 | 3.502E-04 | PDE4B, PDE4D |
| BP | GO:0050896; response to stimulus | GO:0071872; cellular response to epinephrine stimulus | 1.254E-06 | 5.250E-03 | PDE4B, PDE4D |
| BP | GO:0008152; metabolic process | GO:0006198; cAMP catabolic process | 1.463E-06 | 5.250E-03 | PDE4B, PDE4D |
| MF | GO:0003824; catalytic activity | GO:0004115; 3',5'-cyclic-AMP phosphodiesterase activity | 1.688E-06 | 5.250E-03 | PDE4B, PDE4D |
| MF | GO:0005488; binding | GO:0030552; cAMP binding | 4.066E-06 | 8.748E-03 | PDE4B, PDE4D |
| MF | GO:0003824; catalytic activity | GO:0004666; prostaglandin-endoperoxide synthase activity | 3.106E-04 | 1.208E-01 | PTGS1 |
Enriched KEGG Pathways of Target Proteins (Activity≤10μM)
Top 10 KEGG Pathways (ordered by adjusted p-value)
Detailed Information of Enriched KEGG Pathways
| Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|---|
| 09160 Human Diseases | 09164 Substance dependence | hsa05032 | Morphine addiction | 6.125E-05 | 4.900E-04 | PDE4D, PDE4B |
| 09130 Environmental Information Processing | 09132 Signal transduction | hsa04024 | cAMP signaling pathway | 2.936E-04 | 7.829E-04 | PDE4D, PDE4B |
| 09100 Metabolism | 09104 Nucleotide metabolism | hsa00230 | Purine metabolism | 2.297E-04 | 7.829E-04 | PDE4D, PDE4B |
| 09150 Organismal Systems | 09152 Endocrine system | hsa04923 | Regulation of lipolysis in adipocytes | 8.377E-03 | 1.483E-02 | PTGS1 |
| 09100 Metabolism | 09103 Lipid metabolism | hsa00590 | Arachidonic acid metabolism | 9.272E-03 | 1.483E-02 | PTGS1 |
| 09150 Organismal Systems | 09156 Nervous system | hsa04726 | Serotonergic synapse | 1.671E-02 | 2.079E-02 | PTGS1 |
| 09150 Organismal Systems | 09151 Immune system | hsa04611 | Platelet activation | 1.819E-02 | 2.079E-02 | PTGS1 |
| Unclassified | Unclassified | hsa01100 | Metabolic pathways | 1.746E-01 | 1.746E-01 | PTGS1 |
Human Diseases Associated with the Target Proteins of the Plant
Detailed Information of Human Diseases
| ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
|---|---|---|---|
| K00-K95: Diseases of the digestive system | Ulcerative colitis | K51 | PTGS1; |
| NA: NA | Rheumatold arthritis | NA | PTGS1; |
| NA: NA | Miosis during ocular surgery | NA | PTGS1; |
| S00-T88: Injury, poisoning and certain other consequences of external causes | Postoperative inflammation | T81 | PTGS1; |
| C00-D49: Neoplasms | Colorectal cancer | C18-C21 | PTGS1; |
| L00-L99: Diseases of the skin and subcutaneous tissue | Acne vulgaris | L70.0 | PTGS1; |
| G00-G99: Diseases of the nervous system G00-G99 | Neuropathic pain | G64, G90.0 | PTGS1; |
| C00-D49: Neoplasms | Inflammatory disease | C11, C44, K75.9, M00-M25 | PTGS1; |
| K00-K95: Diseases of the digestive system | Inflammatory bowel disease | K50, K51 | PTGS1; |
| N00-N99: Diseases of the genitourinary system | Dysmenorrhea | N94.4-N94.6 | PTGS1; |
| E00-E89: Endocrine, nutritional and metabolic diseases | Dietary shortage | E40-E46 | PTGS1; |
| G00-G99: Diseases of the nervous system G00-G99 | Pain | G64, G90.0, R52, G89 | PTGS1; |
| E00-E89: Endocrine, nutritional and metabolic diseases | Diabetic neuropathy | E11.40 | PTGS1; |
| L00-L99: Diseases of the skin and subcutaneous tissue | Dermatitis | L20-L30 | PTGS1; |
| M00-M99: Diseases of the musculoskeletal system and connective tissue | Osteoarthritis | M15-M19, M47 | PTGS1; |
>> Profiles of ingredients and activity landscape
>> Targets derived from weak experimental activities
