Plant Name: Karwinskia parvifolia
Taxonomic Information:
Plant ID: NPO3206
Plant Latin Name: Karwinskia parvifolia
Taxonomy Genus: Karwinskia
Taxonomy Family: Rhamnaceae
Plant External Links:
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
n.a.
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Collective Molecular Activities of the Plant
List of Human Proteins Collectively Targeted by the Plant
Click Gene ID to Access Activity Profile of Individual Target
| BLM; |
List of Human Cytochrome P450 Enzymes Affected by the Plant
Click Gene ID to Access Activity Profile of Individual Enzyme
| Cytochrome P450 Enzymes: |
|---|
Detailed Information of Target Proteins
| Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|
| Enzyme_unclassified | BLM | Bloom syndrome protein | P54132 | CHEMBL1293237 |
Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)
Detailed Information of Enriched Gene Ontolgy
| GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|
| BP | GO:0009987; cellular process | GO:0000733; DNA strand renaturation | 4.659E-04 | 5.073E-01 | BLM |
| MF | GO:0003824; catalytic activity | GO:0009378; four-way junction helicase activity | 2.589E-04 | 5.073E-01 | BLM |
| MF | GO:0003824; catalytic activity | GO:0043140; ATP-dependent 3'-5' DNA helicase activity | 3.624E-04 | 5.073E-01 | BLM |
| MF | GO:0005488; binding | GO:0036310; annealing helicase activity | 4.142E-04 | 5.073E-01 | BLM |
| CC | GO:0043226; organelle | GO:0000800; lateral element | 8.283E-04 | 6.220E-01 | BLM |
| CC | GO:0044422; organelle part | GO:0000781; chromosome, telomeric region | 8.542E-03 | 1.000E+00 | BLM |
Enriched KEGG Pathways of Target Proteins (Activity≤10μM)
Top 10 KEGG Pathways (ordered by adjusted p-value)
Detailed Information of Enriched KEGG Pathways
| Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|---|
| 09120 Genetic Information Processing | 09124 Replication and repair | hsa03440 | Homologous recombination | 1.450E-03 | 2.650E-03 | BLM |
| 09120 Genetic Information Processing | 09124 Replication and repair | hsa03460 | Fanconi anemia pathway | 2.650E-03 | 2.650E-03 | BLM |
Human Diseases Associated with the Target Proteins of the Plant
Detailed Information of Human Diseases
| ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
|---|
>> Profiles of ingredients and activity landscape
>> Targets derived from weak experimental activities
