Plant Name: Morinda officinalis
Taxonomic Information:
Plant ID: NPO30972
Plant Latin Name: Morinda officinalis
Taxonomy Genus: Morinda
Taxonomy Family: Rubiaceae
Plant External Links:
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
n.a.
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Collective Molecular Activities of the Plant
List of Human Proteins Collectively Targeted by the Plant
Click Gene ID to Access Activity Profile of Individual Target
List of Human Cytochrome P450 Enzymes Affected by the Plant
Click Gene ID to Access Activity Profile of Individual Enzyme
| Cytochrome P450 Enzymes: |
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Detailed Information of Target Proteins
Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)
Detailed Information of Enriched Gene Ontolgy
| GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|
| MF | GO:0005488; binding | GO:0051721; protein phosphatase 2A binding | 6.074E-06 | 1.323E-01 | MAPT, PTPN1 |
| CC | GO:0044464; cell part | GO:0097443; sorting endosome | 9.316E-04 | 4.226E-01 | PTPN1 |
| MF | GO:0005488; binding | GO:0034452; dynactin binding | 1.708E-03 | 4.590E-01 | MAPT |
| CC | GO:0044464; cell part | GO:0030673; axolemma | 2.483E-03 | 5.335E-01 | MAPT |
| MF | GO:0005488; binding | GO:0034185; apolipoprotein binding | 2.483E-03 | 5.335E-01 | MAPT |
Enriched KEGG Pathways of Target Proteins (Activity≤10μM)
Top 10 KEGG Pathways (ordered by adjusted p-value)
Detailed Information of Enriched KEGG Pathways
| Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|---|
| 09140 Cellular Processes | 09144 Cellular community - eukaryotes | hsa04520 | Adherens junction | 1.106E-02 | 3.122E-02 | PTPN1 |
| 09160 Human Diseases | 09166 Endocrine and metabolic diseases | hsa04931 | Insulin resistance | 1.626E-02 | 3.122E-02 | PTPN1 |
| 09160 Human Diseases | 09162 Immune diseases | hsa05322 | Systemic lupus erythematosus | 2.011E-02 | 3.122E-02 | ELANE |
| 09150 Organismal Systems | 09152 Endocrine system | hsa04910 | Insulin signaling pathway | 2.071E-02 | 3.122E-02 | PTPN1 |
| 09160 Human Diseases | 09163 Neurodegenerative diseases | hsa05010 | Alzheimer's disease | 2.499E-02 | 3.122E-02 | MAPT |
| 09130 Environmental Information Processing | 09132 Signal transduction | hsa04010 | MAPK signaling pathway | 3.777E-02 | 3.777E-02 | MAPT |
| 09160 Human Diseases | 09161 Cancers | hsa05202 | Transcriptional misregulation in cancer | 2.676E-02 | 3.122E-02 | ELANE |
Human Diseases Associated with the Target Proteins of the Plant
Detailed Information of Human Diseases
| ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
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>> Profiles of ingredients and activity landscape
>> Targets derived from weak experimental activities
