Plant Name: Clausena dunniana
Taxonomic Information:
Plant ID: NPO28622
Plant Latin Name: Clausena dunniana
Taxonomy Genus: Clausena
Taxonomy Family: Rutaceae
Plant External Links:
NCBI TaxonomyDB:
1224754
Plant-of-the-World-Online:
n.a.
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Collective Molecular Activities of the Plant
List of Human Proteins Collectively Targeted by the Plant
Click Gene ID to Access Activity Profile of Individual Target
List of Human Cytochrome P450 Enzymes Affected by the Plant
Click Gene ID to Access Activity Profile of Individual Enzyme
| Cytochrome P450 Enzymes: |
|---|
Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)
Detailed Information of Enriched Gene Ontolgy
| GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|
| MF | GO:0003824; catalytic activity | GO:0004064; arylesterase activity | 8.041E-08 | 1.751E-03 | CA1, CA2 |
| MF | GO:0003824; catalytic activity | GO:0004089; carbonate dehydratase activity | 5.629E-07 | 6.128E-03 | CA1, CA2 |
| BP | GO:0008152; metabolic process | GO:0006730; one-carbon metabolic process | 3.377E-06 | 2.451E-02 | CA1, CA2 |
| BP | GO:0051179; localization | GO:0015701; bicarbonate transport | 5.071E-06 | 2.761E-02 | CA1, CA2 |
| BP | GO:0009987; cellular process | GO:0032849; positive regulation of cellular pH reduction | 3.106E-04 | 4.509E-01 | CA2 |
| CC | GO:0044464; cell part | GO:0043209; myelin sheath | 1.516E-02 | 1.000E+00 | CA2 |
| CC | GO:0016020; membrane | GO:0016323; basolateral plasma membrane | 1.917E-02 | 1.000E+00 | CA2 |
| CC | GO:0044421; extracellular region part | GO:0070062; extracellular exosome | 2.116E-02 | 1.000E+00 | CA1, CA2 |
| CC | GO:0044464; cell part | GO:0030424; axon | 2.643E-02 | 1.000E+00 | CA2 |
| MF | GO:0005488; binding | GO:0046914; transition metal ion binding | 3.072E-03 | 1.000E+00 | CA1, CA2 |
| MF | GO:0003824; catalytic activity | GO:0016787; hydrolase activity | 1.835E-02 | 1.000E+00 | CA1, CA2 |
Enriched KEGG Pathways of Target Proteins (Activity≤10μM)
Top 10 KEGG Pathways (ordered by adjusted p-value)
Detailed Information of Enriched KEGG Pathways
| Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|---|
| 09100 Metabolism | 09102 Energy metabolism | hsa00910 | Nitrogen metabolism | 6.800E-07 | 4.080E-06 | CA1, CA2 |
| 09150 Organismal Systems | 09155 Excretory system | hsa04966 | Collecting duct acid secretion | 2.698E-03 | 5.396E-03 | CA2 |
| 09150 Organismal Systems | 09155 Excretory system | hsa04964 | Proximal tubule bicarbonate reclamation | 2.299E-03 | 5.396E-03 | CA2 |
| 09150 Organismal Systems | 09154 Digestive system | hsa04971 | Gastric acid secretion | 7.386E-03 | 8.864E-03 | CA2 |
| 09150 Organismal Systems | 09154 Digestive system | hsa04976 | Bile secretion | 7.088E-03 | 8.864E-03 | CA2 |
| 09150 Organismal Systems | 09154 Digestive system | hsa04972 | Pancreatic secretion | 9.577E-03 | 9.577E-03 | CA2 |
Human Diseases Associated with the Target Proteins of the Plant
Detailed Information of Human Diseases
| ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
|---|
>> Profiles of ingredients and activity landscape
>> Targets derived from weak experimental activities
