Plant ID: NPO26335
Plant Latin Name: Carpesium abrotanoides
Taxonomy Genus: Carpesium
Taxonomy Family: Asteraceae
NCBI TaxonomyDB:
119172
Plant-of-the-World-Online:
189330-1
Unknown.
Turkey; Afghanistan; Italy; Nepal; Georgia; Laos; Australia; Iran; China; Belgium; Germany; Iraq; Kazakhstan; Netherlands; Poland; Vietnam; Japan; Switzerland; Russia; Bulgaria; Myanmar; South Africa; India; Austria; Greece; Hungary; Taiwan
Cytochrome P450 Enzymes: | CYP3A4; |
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Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|
Cytochrome P450 family 3 | CYP3A4 | Cytochrome P450 3A4 | P08684 | CHEMBL340 |
Enzyme_unclassified | ALOX15 | Arachidonate 15-lipoxygenase | P16050 | CHEMBL2903 |
Enzyme_unclassified | ALDH1A1 | Aldehyde dehydrogenase 1A1 | P00352 | CHEMBL3577 |
GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|
BP | GO:0008152; metabolic process | GO:0055114; oxidation-reduction process | 1.002E-04 | 2.601E-01 | ALDH1A1, ALOX15, CYP3A4 |
BP | GO:0008152; metabolic process | GO:2001303; lipoxin A4 biosynthetic process | 3.106E-04 | 2.601E-01 | ALOX15 |
MF | GO:0003824; catalytic activity | GO:0016491; oxidoreductase activity | 5.376E-05 | 2.601E-01 | ALDH1A1, ALOX15, CYP3A4 |
MF | GO:0003824; catalytic activity | GO:0047977; hepoxilin-epoxide hydrolase activity | 3.106E-04 | 2.601E-01 | ALOX15 |
CC | GO:0044464; cell part | GO:0031234; extrinsic component of cytoplasmic side of plasma membrane | 1.114E-02 | 1.000E+00 | ALOX15 |
Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|---|
09100 Metabolism | 09103 Lipid metabolism | hsa00591 | Linoleic acid metabolism | 6.085E-06 | 6.693E-05 | ALOX15, CYP3A4 |
09100 Metabolism | 09108 Metabolism of cofactors and vitamins | hsa00830 | Retinol metabolism | 3.114E-05 | 1.712E-04 | ALDH1A1, CYP3A4 |
Unclassified | Unclassified | hsa01100 | Metabolic pathways | 2.372E-04 | 8.698E-04 | ALOX15, ALDH1A1, CYP3A4 |
09100 Metabolism | 09111 Xenobiotics biodegradation and metabolism | hsa00983 | Drug metabolism - other enzymes | 6.884E-03 | 1.334E-02 | CYP3A4 |
09100 Metabolism | 09103 Lipid metabolism | hsa00590 | Arachidonic acid metabolism | 9.272E-03 | 1.334E-02 | ALOX15 |
09100 Metabolism | 09103 Lipid metabolism | hsa00140 | Steroid hormone biosynthesis | 8.675E-03 | 1.334E-02 | CYP3A4 |
09100 Metabolism | 09111 Xenobiotics biodegradation and metabolism | hsa00982 | Drug metabolism - cytochrome P450 | 1.031E-02 | 1.334E-02 | CYP3A4 |
09100 Metabolism | 09111 Xenobiotics biodegradation and metabolism | hsa00980 | Metabolism of xenobiotics by cytochrome P450 | 1.091E-02 | 1.334E-02 | CYP3A4 |
09150 Organismal Systems | 09154 Digestive system | hsa04976 | Bile secretion | 1.061E-02 | 1.334E-02 | CYP3A4 |
09160 Human Diseases | 09161 Cancers | hsa05204 | Chemical carcinogenesis | 1.225E-02 | 1.348E-02 | CYP3A4 |
ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
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