Plant Name: Buxus natalensis
Taxonomic Information:
Plant ID: NPO26132
Plant Latin Name: Buxus natalensis
Taxonomy Genus: Buxus
Taxonomy Family: Buxaceae
Plant External Links:
NCBI TaxonomyDB:
1237406
Plant-of-the-World-Online:
128681-1
Used in Medicines:
Unknown.
Geographical Distribution:
South Africa
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Collective Molecular Activities of the Plant
List of Human Proteins Collectively Targeted by the Plant
Click Gene ID to Access Activity Profile of Individual Target
| ACHE; |
List of Human Cytochrome P450 Enzymes Affected by the Plant
Click Gene ID to Access Activity Profile of Individual Enzyme
| Cytochrome P450 Enzymes: |
|---|
Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)
Detailed Information of Enriched Gene Ontolgy
| GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|
| MF | GO:0003824; catalytic activity | GO:0003990; acetylcholinesterase activity | 1.035E-04 | 4.509E-01 | ACHE |
| CC | GO:0044464; cell part | GO:0009986; cell surface | 2.806E-02 | 1.000E+00 | ACHE |
| CC | GO:0044464; cell part | GO:0048471; perinuclear region of cytoplasm | 3.350E-02 | 1.000E+00 | ACHE |
| MF | GO:0005488; binding | GO:0042562; hormone binding | 4.400E-03 | 1.000E+00 | ACHE |
| MF | GO:0005488; binding | GO:0042277; peptide binding | 1.387E-02 | 1.000E+00 | ACHE |
| MF | GO:0003824; catalytic activity | GO:0017171; serine hydrolase activity | 1.465E-02 | 1.000E+00 | ACHE |
| MF | Unclassified; | GO:0032403; protein complex binding | 4.116E-02 | 1.000E+00 | ACHE |
Enriched KEGG Pathways of Target Proteins (Activity≤10μM)
Top 10 KEGG Pathways (ordered by adjusted p-value)
Detailed Information of Enriched KEGG Pathways
| Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|---|
| 09150 Organismal Systems | 09156 Nervous system | hsa04725 | Cholinergic synapse | 5.550E-03 | 5.550E-03 | ACHE |
| 09100 Metabolism | 09103 Lipid metabolism | hsa00564 | Glycerophospholipid metabolism | 4.750E-03 | 5.550E-03 | ACHE |
Human Diseases Associated with the Target Proteins of the Plant
Detailed Information of Human Diseases
| ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
|---|
>> Profiles of ingredients and activity landscape
>> Targets derived from weak experimental activities
