Plant Name: Crinum yemense
Taxonomic Information:
Plant ID: NPO23263
Plant Latin Name: Crinum yemense
Taxonomy Genus: Crinum
Taxonomy Family: Amaryllidaceae
Plant External Links:
NCBI TaxonomyDB:
112538
Plant-of-the-World-Online:
n.a.
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Collective Molecular Activities of the Plant
List of Human Proteins Collectively Targeted by the Plant
Click Gene ID to Access Activity Profile of Individual Target
| ABCG2; | |
| SMN1;SMN2; |
List of Human Cytochrome P450 Enzymes Affected by the Plant
Click Gene ID to Access Activity Profile of Individual Enzyme
| Cytochrome P450 Enzymes: |
|---|
Detailed Information of Target Proteins
| Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|
| ATP-binding cassette | ABCG2 | ATP-binding cassette sub-family G member 2 | Q9UNQ0 | CHEMBL5393 |
| Methyl-lysine/arginine binding protein | SMN1;SMN2 | Survival motor neuron protein | Q16637 | CHEMBL1293232 |
Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)
Detailed Information of Enriched Gene Ontolgy
| GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|
| BP | GO:0051179; localization | GO:0042908; xenobiotic transport | 1.035E-03 | 1.000E+00 | ABCG2 |
| BP | GO:0008152; metabolic process | GO:0046415; urate metabolic process | 1.346E-03 | 1.000E+00 | ABCG2 |
| BP | GO:0051179; localization | GO:0033344; cholesterol efflux | 2.484E-03 | 1.000E+00 | ABCG2 |
| BP | GO:0051179; localization | GO:0006855; drug transmembrane transport | 6.616E-03 | 1.000E+00 | ABCG2 |
| CC | GO:0032991; macromolecular complex | GO:0043235; receptor complex | 3.306E-02 | 1.000E+00 | ABCG2 |
| MF | GO:0005215; transporter activity | GO:0008559; xenobiotic transmembrane transporting ATPase activity | 7.247E-04 | 1.000E+00 | ABCG2 |
Enriched KEGG Pathways of Target Proteins (Activity≤10μM)
Top 10 KEGG Pathways (ordered by adjusted p-value)
Detailed Information of Enriched KEGG Pathways
| Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|---|
| 09130 Environmental Information Processing | 09131 Membrane transport | hsa02010 | ABC transporters | 4.395E-03 | 7.088E-03 | ABCG2 |
| 09150 Organismal Systems | 09154 Digestive system | hsa04976 | Bile secretion | 7.088E-03 | 7.088E-03 | ABCG2 |
Human Diseases Associated with the Target Proteins of the Plant
Detailed Information of Human Diseases
| ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
|---|
>> Profiles of ingredients and activity landscape
>> Targets derived from weak experimental activities
