Plant Name: Flacourtia indica
Taxonomic Information:
Plant ID: NPO22355
Plant Latin Name: Flacourtia indica
Taxonomy Genus: Flacourtia
Taxonomy Family: Salicaceae
Plant External Links:
NCBI TaxonomyDB:
210376
Plant-of-the-World-Online:
n.a.
Used in Medicines:
Country/Region:
Madagascar; Angola; South Africa; Tanzania; India; Zimbabwe; Rwanda; Swaziland; Laos; Kenya; ThailandTraditional Medicine System:
Geographical Distribution:
Madagascar; Angola; South Africa; Tanzania; India; Zimbabwe; Rwanda; Swaziland; Laos; Kenya; Thailand
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Collective Molecular Activities of the Plant
List of Human Proteins Collectively Targeted by the Plant
Click Gene ID to Access Activity Profile of Individual Target
| AKR1B1; |
List of Human Cytochrome P450 Enzymes Affected by the Plant
Click Gene ID to Access Activity Profile of Individual Enzyme
| Cytochrome P450 Enzymes: |
|---|
Detailed Information of Target Proteins
| Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|
| Enzyme_unclassified | AKR1B1 | Aldose reductase | P15121 | CHEMBL1900 |
Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)
Detailed Information of Enriched Gene Ontolgy
| GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|
| CC | GO:0044464; cell part | GO:0048471; perinuclear region of cytoplasm | 3.350E-02 | 1.000E+00 | AKR1B1 |
| MF | GO:0003824; catalytic activity | GO:0009055; electron transfer activity | 5.591E-03 | 1.000E+00 | AKR1B1 |
Enriched KEGG Pathways of Target Proteins (Activity≤10μM)
Top 10 KEGG Pathways (ordered by adjusted p-value)
Detailed Information of Enriched KEGG Pathways
| Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
|---|---|---|---|---|---|---|
| 09100 Metabolism | 09101 Carbohydrate metabolism | hsa00040 | Pentose and glucuronate interconversions | 1.800E-03 | 3.000E-03 | AKR1B1 |
| 09100 Metabolism | 09101 Carbohydrate metabolism | hsa00052 | Galactose metabolism | 1.500E-03 | 3.000E-03 | AKR1B1 |
| 09100 Metabolism | 09103 Lipid metabolism | hsa00561 | Glycerolipid metabolism | 2.950E-03 | 3.688E-03 | AKR1B1 |
| 09100 Metabolism | 09101 Carbohydrate metabolism | hsa00051 | Fructose and mannose metabolism | 1.600E-03 | 3.000E-03 | AKR1B1 |
| Unclassified | Unclassified | hsa01100 | Metabolic pathways | 6.195E-02 | 6.195E-02 | AKR1B1 |
Human Diseases Associated with the Target Proteins of the Plant
Detailed Information of Human Diseases
| ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
|---|
>> Profiles of ingredients and activity landscape
>> Targets derived from weak experimental activities
