CMAUP Plant Collective Molecular Activities

Plant Name: Aframomum alboviolaceum

Taxonomic Information:

Plant ID: NPO22090
Plant Latin Name: Aframomum alboviolaceum
Taxonomy Genus: Aframomum
Taxonomy Family: Zingiberaceae

Plant External Links:

NCBI TaxonomyDB: 637922
Plant-of-the-World-Online: 871826-1

Used in Medicines:

Unknown.

Geographical Distribution:

Sudan; Guinea; Nigeria; Cameroon; Cote d'Ivoire; Benin; Ghana; Zambia; Malawi; Togo; Sierra Leone; Liberia; Tanzania; Gabon; Guinea-Bissau; Angola; Equatorial Guinea; Burkina Faso; Senegal; Congo; Mozambique; Uganda; Burundi; Kenya

Geographical Distribution

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See the Plant Occurrence Worldwide with Latitude and Longitude Available

Collective Molecular Activities of the Plant

List of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Target

Target Class	Target Proteins
Nuclear hormone receptor subfamily 1 group H	NR1H4;

List of Human Cytochrome P450 Enzymes Affected by the Plant

Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Enzyme

Cytochrome P450 Enzymes:

Detailed Information of Target Proteins

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Search:

Protein Class	Gene ID	Protein Name	Uniprot ID	Target ChEMBL ID
Nuclear hormone receptor subfamily 1 group H	NR1H4	Bile acid receptor FXR	Q96RI1	CHEMBL2047

Showing 1 to 1 of 1 entries

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GO Type	GO Category	Enriched GO Terms	p-Value	Adjusted p-Value	Enriched Genes
MF	GO:0060089; molecular transducer activity	GO:0038181; bile acid receptor activity	1.553E-04	1.537E-01	NR1H4
MF	GO:0060089; molecular transducer activity	GO:0004887; thyroid hormone receptor activity	3.624E-04	2.546E-01	NR1H4
MF	GO:0005488; binding	GO:0046965; retinoid X receptor binding	7.766E-04	3.676E-01	NR1H4
MF	GO:0005488; binding	GO:0016922; ligand-dependent nuclear receptor binding	1.087E-03	4.227E-01	NR1H4

Data Section	Select to Download
1. General Info & Plant Usage & Geographical Distribution
2. Human Target Proteins
3. Target Gene Ontology
4. Target KEGG Pathway
5. Related Human Diseases

Plant Name: Aframomum alboviolaceum

Taxonomic Information:

Plant External Links:

Used in Medicines:

Geographical Distribution:

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Collective Molecular Activities of the Plant

List of Human Proteins Collectively Targeted by the Plant

List of Human Cytochrome P450 Enzymes Affected by the Plant

Detailed Information of Target Proteins

Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)

Detailed Information of Enriched Gene Ontolgy

Enriched KEGG Pathways of Target Proteins (Activity≤10μM)

Top 10 KEGG Pathways (ordered by adjusted p-value)

Detailed Information of Enriched KEGG Pathways

Human Diseases Associated with the Target Proteins of the Plant

Detailed Information of Human Diseases

>> Profiles of ingredients and activity landscape

>> Collective molecular activities profile at 10μM cutoff

>> Targets derived from weak experimental activities