CMAUP Plant Collective Molecular Activities

Plant Name: Prunus mahaleb

Taxonomic Information:

Plant ID: NPO21639
Plant Latin Name: Prunus mahaleb
Taxonomy Genus: Prunus
Taxonomy Family: Rosaceae

Plant External Links:

NCBI TaxonomyDB: 129217
Plant-of-the-World-Online: 729931-1

Used in Medicines:

Country/Region:

Jordan; Iraq; India

Traditional Medicine System:

Medicinal Functions:

Tonic

Geographical Distribution:

Canada; Turkey; Italy; Turkmenistan; France; Argentina; Norway; Uzbekistan; Australia; Iran; Jordan; Belgium; Germany; Iraq; Kazakhstan; Spain; Ukraine; Netherlands; Denmark; United States; Morocco; Sweden; Switzerland; Russia; Bulgaria; Pakistan; Romania; Albania; Portugal; India; United Kingdom; Austria; Greece; Hungary; Tajikistan

Example Image

Geographical Distribution

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See the Plant Occurrence Worldwide with Latitude and Longitude Available

Collective Molecular Activities of the Plant

List of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Target

Target Class	Target Proteins
Protein Phosphatase	PTPN2;

List of Human Cytochrome P450 Enzymes Affected by the Plant

Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Enzyme

Cytochrome P450 Enzymes:

Detailed Information of Target Proteins

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Search:

Protein Class	Gene ID	Protein Name	Uniprot ID	Target ChEMBL ID
Protein Phosphatase	PTPN2	T-cell protein-tyrosine phosphatase	P17706	CHEMBL3807

Showing 1 to 1 of 1 entries

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GO Type	GO Category	Enriched GO Terms	p-Value	Adjusted p-Value	Enriched Genes
CC	GO:0044464; cell part	GO:0005783; endoplasmic reticulum	4.887E-02	1.000E+00	PTPN2
MF	GO:0005488; binding	GO:0097677; STAT family protein binding	3.106E-04	3.560E-01	PTPN2
MF	GO:0003824; catalytic activity	GO:0004726; non-membrane spanning protein tyrosine phosphatase activity	4.142E-04	3.921E-01	PTPN2
MF	GO:0005488; binding	GO:0030971; receptor tyrosine kinase binding	2.899E-03	9.018E-01	PTPN2
MF	GO:0003824; catalytic activity	GO:0016791; phosphatase activity	1.408E-02	1.000E+00	PTPN2
MF	GO:0005488; binding	GO:0019901; protein kinase binding	2.992E-02	1.000E+00	PTPN2
MF	Unclassified;	GO:0032403; protein complex binding	4.116E-02	1.000E+00	PTPN2

Data Section	Select to Download
1. General Info & Plant Usage & Geographical Distribution
2. Human Target Proteins
3. Target Gene Ontology
4. Target KEGG Pathway
5. Related Human Diseases

Plant Name: Prunus mahaleb

Taxonomic Information:

Plant External Links:

Used in Medicines:

Country/Region:

Traditional Medicine System:

Medicinal Functions:

Geographical Distribution:

Example Image

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Collective Molecular Activities of the Plant

List of Human Proteins Collectively Targeted by the Plant

List of Human Cytochrome P450 Enzymes Affected by the Plant

Detailed Information of Target Proteins

Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)

Detailed Information of Enriched Gene Ontolgy

Enriched KEGG Pathways of Target Proteins (Activity≤10μM)

Top 10 KEGG Pathways (ordered by adjusted p-value)

Detailed Information of Enriched KEGG Pathways

Human Diseases Associated with the Target Proteins of the Plant

Detailed Information of Human Diseases

>> Profiles of ingredients and activity landscape

>> Collective molecular activities profile at 10μM cutoff

>> Targets derived from weak experimental activities