ICD10 Disease Category |
Disease Name |
ICD10 Code |
Associated Disease Targets (Association Ref: TTD database) |
NA: NA |
Menopausal disorder |
NA |
ESR1; |
C00-D49: Neoplasms |
Thyroid cancer |
C73 |
TSHR; |
N00-N99: Diseases of the genitourinary system |
Menorrhagia |
N92.0 |
ESR1; |
N00-N99: Diseases of the genitourinary system |
Menopause symptoms |
N95.0 |
ESR1; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Metabolic disorders |
E70-E89 |
HSD11B1; |
NA: NA |
Postmenopausal disorder |
NA |
ESR1; |
N00-N99: Diseases of the genitourinary system |
Post-menopausal vaginal atrophy |
N95.2 |
ESR1; |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Rheumatoid arthritis |
M05-M06 |
MMP1; |
K00-K95: Diseases of the digestive system |
Duodenal ulcers |
K25-K27 |
CA2; |
F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Female sexual dysfunction |
F52 |
ESR1; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Non-insulin dependent diabetes |
E11.9 |
HSD11B1; |
C00-D49: Neoplasms |
Prostate cancer |
C61 |
ESR1; FLT3; |
Z00-Z99: Factors influencing health status and contact with health services |
Contraception |
Z30 |
ESR1; |
G00-G99: Diseases of the nervous system G00-G99 |
Multiple scierosis |
G35 |
ESR1; |
I00-I99: Diseases of the circulatory system |
Aortic aneurysm |
I71 |
MMP12; |
C00-D49: Neoplasms |
Colorectal cancer |
C18-C21 |
FLT3; MMP9; |
C00-D49: Neoplasms |
Colon cancer |
C50 |
FLT3; |
K00-K95: Diseases of the digestive system |
Ulcerative colitis |
K51 |
MMP9; |
I00-I99: Diseases of the circulatory system |
Pulmonary arterial hypertension |
I27.0, I27.2 |
HIF1A; |
C00-D49: Neoplasms |
Adrenocortical carcinoma |
C74.0 |
ESR1; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Metabolic syndrome x |
E88.81 |
HSD11B1; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Hypogonadism |
E23.0, E28.3, E29.1 |
ESR1; |
A00-B99: Certain infectious and parasitic diseases |
Trematode infection |
B66.9 |
ESR1; |
C00-D49: Neoplasms |
Thyroid cancer diagnosis |
C73 |
TSHR; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Type 2 diabetes |
E11 |
HSD11B1; NFKB1; |
N00-N99: Diseases of the genitourinary system |
Vagina disease |
N76.0 |
ESR1; |
I00-I99: Diseases of the circulatory system |
Edema associated with congestive heart failure |
I50, R60.9 |
CA2; |
L00-L99: Diseases of the skin and subcutaneous tissue |
Psoriasis |
L40 |
FLT3; |
C00-D49: Neoplasms |
Renal cell carcinoma |
NA |
MMP2; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Hypercholesterolemia |
E78 |
HSD11B1; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Female hypogonadism |
E23, E28 |
ESR1; |
C00-D49: Neoplasms |
Non-small-cell lung cancer |
NA |
MMP2; |
N00-N99: Diseases of the genitourinary system |
Infertility |
N97.0 |
ESR1; |
I00-I99: Diseases of the circulatory system |
Atherosclerosis |
I70 |
MMP12; HSD11B1; |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Arthralgia |
M25.5 |
ESR1; |
J00-J99: Diseases of the respiratory system |
Asthma |
J45 |
MMP12; |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Arthritis |
M00-M25 |
MMP1; |
H00-H59: Diseases of the eye and adnexa |
Eye disorders |
H00-H59 |
ESR1; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Autoimmune diabetes |
E08-E13 |
ESR1; |
L00-L99: Diseases of the skin and subcutaneous tissue |
Acne vulgaris |
L70.0 |
ESR1; MMP2; |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Atrophy |
M62.571 |
ESR1; |
C00-D49: Neoplasms |
Lymphoma |
C81-C86 |
HIF1A; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Estrogen deficiency |
E28.39 |
ESR1; |
NA: NA |
Edema |
NA |
CA2; |
C00-D49: Neoplasms |
Solid tumours |
C00-D48 |
FLT3; HIF1A; MMP9; MMP2; |
C00-D49: Neoplasms |
Carcinoma |
D00-D09 |
ESR1; |
NA: NA |
Anaplastic mixed oligoastrocytoma |
NA |
FLT3; |
N00-N99: Diseases of the genitourinary system |
Dysmenorrhea |
N94.4-N94.6 |
ESR1; |
N00-N99: Diseases of the genitourinary system |
Dyspareunia |
N94.1 |
ESR1; |
C00-D49: Neoplasms |
CLL |
NA |
FLT3; |
NA: NA |
GIST |
NA |
FLT3; |
C00-D49: Neoplasms |
Brain cancer |
C71, D33 |
ESR1; |
C00-D49: Neoplasms |
Breast cancer |
C50 |
ESR1; FLT3; |
C00-D49: Neoplasms |
Leukemia |
C90-C95 |
ESR1; FLT3; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Diabetic nephropathy |
E11.21 |
MMP1; |
J00-J99: Diseases of the respiratory system |
Airway inflammation |
J00-J99 |
FLT3; |
C00-D49: Neoplasms |
Gliosarcoma |
NA |
FLT3; |
C00-D49: Neoplasms |
Glioblastoma |
NA |
FLT3; |
NA: NA |
Gonorrheal vaginitis |
NA |
ESR1; |
F01-F99: Mental, Behavioral and Neurodevelopmental disorders |
Insomnia |
F51.0, G47.0 |
CA2; |
N00-N99: Diseases of the genitourinary system |
Atrophic vaginitis |
N95.2 |
ESR1; |
I00-I99: Diseases of the circulatory system |
Neurological disease |
I21, I22, R52, R52.1-R52.2, R60.9, G89 |
ESR1; |
W85-W99: Exposure to electric current, radiation and extreme ambient air temperature and pressure |
Diagnostic test to differentiate primary and secondary hypothyroidism |
W88 |
TSHR; |
C00-D49: Neoplasms |
Advanced prostate cancer |
C61 |
ESR1; |
N00-N99: Diseases of the genitourinary system |
Female infertility due to anovulation |
N97.0 |
ESR1; |
N00-N99: Diseases of the genitourinary system |
Female infertility |
N97.0 |
ESR1; |
C00-D49: Neoplasms |
Myeloid leukemia |
C92 |
FLT3; |
C00-D49: Neoplasms |
Myelofibrosis |
C94.4, D47.4 |
FLT3; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Diabetes |
E23.2, N25.1 |
HSD11B1; |
C00-D49: Neoplasms |
AML |
NA |
FLT3; |
NA: NA |
Hematopoietic stem cell transplantation |
NA |
FLT3; |
G00-G99: Diseases of the nervous system G00-G99 |
Pain |
G64, G90.0, R52, G89 |
ESR1; |
C00-D49: Neoplasms |
Pancreatic cancer |
C25 |
FLT3; MMP2; |
J00-J99: Diseases of the respiratory system |
Chronic obstructive pulmonary disease |
J40-J44, J47 |
MMP12; |
C00-D49: Neoplasms |
Acute lymphoblastic leukemia |
C91.0 |
FLT3; |
C00-D49: Neoplasms |
Ovarian cancer |
C56 |
MMP2; |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Osteoporosis |
M80-M81, Z79.890 |
ESR1; |
J00-J99: Diseases of the respiratory system |
Influenza virus |
J11.1 |
HSD11B1; |
C00-D49: Neoplasms |
Inflammatory disease |
C11, C44, K75.9, M00-M25 |
MMP12; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Obesity |
E66 |
HSD11B1; |
C00-D49: Neoplasms |
Acute myeloid leukemia |
C92.0 |
FLT3; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Lipid metabolism disorder |
E75-E78 |
HSD11B1; |
Q00-Q99: Congenital malformations, deformations and chromosomal abnormalities |
Osteopetrosis |
Q78.2 |
ESR1; |
Z00-Z99: Factors influencing health status and contact with health services |
Oral contraceptive |
Z30 |
ESR1; |
M00-M99: Diseases of the musculoskeletal system and connective tissue |
Osteoarthritis |
M15-M19, M47 |
MMP2; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Hyperlipidaemia |
E78 |
ESR1; |
N00-N99: Diseases of the genitourinary system |
Irregularities |
N92.6 |
ESR1; |
C00-D49: Neoplasms |
Cancer |
C00-C96 |
ESR1; NFKB1; FLT3; HIF1A; MMP9; MMP2; |
C00-D49: Neoplasms |
Lung cancer |
C33-C34 |
MMP2; |
H00-H59: Diseases of the eye and adnexa |
Open-angle glaucoma |
H40-H42 |
CA4; CA2; |
H00-H59: Diseases of the eye and adnexa |
Ocular hypertension |
H40.0 |
CA4; HSD11B1; |
A00-B99: Certain infectious and parasitic diseases |
Human immunodeficiency virus infection |
B20-B26 |
FLT3; |
Z00-Z99: Factors influencing health status and contact with health services |
Hormone replacement therapy |
Z79.890 |
ESR1; |
I00-I99: Diseases of the circulatory system |
Stroke |
I61-I63, I80-I82 |
MMP9; |
E00-E89: Endocrine, nutritional and metabolic diseases |
Hormone deficiency |
E00-E90 |
ESR1; |
C00-D49: Neoplasms |
Hormone refractory prostate cancer |
C61 |
ESR1; |
I00-I99: Diseases of the circulatory system |
High blood pressure |
I10-I16 |
CA2; |