Plant ID: NPO15367
Plant Latin Name: Croton regelianus
Taxonomy Genus: Croton
Taxonomy Family: Euphorbiaceae
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
n.a.
Cytochrome P450 Enzymes: | CYP3A4; |
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Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|
Cytochrome P450 family 3 | CYP3A4 | Cytochrome P450 3A4 | P08684 | CHEMBL340 |
Hydrolase | GAA | Lysosomal alpha-glucosidase | P10253 | CHEMBL2608 |
Methyl-lysine/arginine binding protein | SMN1;SMN2 | Survival motor neuron protein | Q16637 | CHEMBL1293232 |
GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|
BP | GO:0008152; metabolic process | GO:0009822; alkaloid catabolic process | 4.659E-04 | 5.636E-01 | CYP3A4 |
BP | GO:0008152; metabolic process | GO:0000023; maltose metabolic process | 4.659E-04 | 5.636E-01 | GAA |
MF | GO:0003824; catalytic activity | GO:0004574; oligo-1,6-glucosidase activity | 3.106E-04 | 5.636E-01 | GAA |
MF | GO:0003824; catalytic activity | GO:0070576; vitamin D 24-hydroxylase activity | 4.659E-04 | 5.636E-01 | CYP3A4 |
MF | GO:0003824; catalytic activity | GO:0032450; maltose alpha-glucosidase activity | 4.659E-04 | 5.636E-01 | GAA |
Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|---|
09100 Metabolism | 09103 Lipid metabolism | hsa00591 | Linoleic acid metabolism | 4.344E-03 | 1.324E-02 | CYP3A4 |
09100 Metabolism | 09101 Carbohydrate metabolism | hsa00500 | Starch and sucrose metabolism | 8.377E-03 | 1.324E-02 | GAA |
09100 Metabolism | 09111 Xenobiotics biodegradation and metabolism | hsa00983 | Drug metabolism - other enzymes | 6.884E-03 | 1.324E-02 | CYP3A4 |
09100 Metabolism | 09101 Carbohydrate metabolism | hsa00052 | Galactose metabolism | 4.493E-03 | 1.324E-02 | GAA |
Unclassified | Unclassified | hsa01100 | Metabolic pathways | 1.103E-02 | 1.324E-02 | GAA, CYP3A4 |
09100 Metabolism | 09108 Metabolism of cofactors and vitamins | hsa00830 | Retinol metabolism | 9.719E-03 | 1.324E-02 | CYP3A4 |
09100 Metabolism | 09103 Lipid metabolism | hsa00140 | Steroid hormone biosynthesis | 8.675E-03 | 1.324E-02 | CYP3A4 |
09100 Metabolism | 09111 Xenobiotics biodegradation and metabolism | hsa00982 | Drug metabolism - cytochrome P450 | 1.031E-02 | 1.324E-02 | CYP3A4 |
09100 Metabolism | 09111 Xenobiotics biodegradation and metabolism | hsa00980 | Metabolism of xenobiotics by cytochrome P450 | 1.091E-02 | 1.324E-02 | CYP3A4 |
09150 Organismal Systems | 09154 Digestive system | hsa04976 | Bile secretion | 1.061E-02 | 1.324E-02 | CYP3A4 |
ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
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