CMAUP Plant Collective Molecular Activities

Plant Name: Toona ciliata

Taxonomic Information:

Plant ID: NPO13083
Plant Latin Name: Toona ciliata
Taxonomy Genus: Toona
Taxonomy Family: Meliaceae

Plant External Links:

NCBI TaxonomyDB: 67918
Plant-of-the-World-Online: n.a.

Used in Medicines:

Country/Region:

Thailand

Traditional Medicine System:

Geographical Distribution:

Thailand

Example Image

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Collective Molecular Activities of the Plant

List of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Target

Target Class	Target Proteins
Enzyme_unclassified	ALDH1A1;

List of Human Cytochrome P450 Enzymes Affected by the Plant

Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Enzyme

Cytochrome P450 Enzymes:

Detailed Information of Target Proteins

Protein Class	Gene ID	Protein Name	Uniprot ID	Target ChEMBL ID
Enzyme_unclassified	ALDH1A1	Aldehyde dehydrogenase 1A1	P00352	CHEMBL3577

Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)

Detailed Information of Enriched Gene Ontolgy

GO Type	GO Category	Enriched GO Terms	p-Value	Adjusted p-Value	Enriched Genes
BP	GO:0008152; metabolic process	GO:0006069; ethanol oxidation	6.212E-04	1.000E+00	ALDH1A1
BP	GO:0008152; metabolic process	GO:0042572; retinol metabolic process	1.553E-03	1.000E+00	ALDH1A1
BP	GO:0008152; metabolic process	GO:0017144; drug metabolic process	2.733E-02	1.000E+00	ALDH1A1
MF	GO:0005488; binding	GO:0005497; androgen binding	2.071E-04	1.000E+00	ALDH1A1
MF	GO:0003824; catalytic activity	GO:0001758; retinal dehydrogenase activity	3.624E-04	1.000E+00	ALDH1A1
MF	GO:0005488; binding	GO:0051287; NAD binding	3.054E-03	1.000E+00	ALDH1A1

Enriched KEGG Pathways of Target Proteins (Activity≤10μM)

Top 10 KEGG Pathways (ordered by adjusted p-value)

Detailed Information of Enriched KEGG Pathways

Pathway Category Top Level	Pathway Category Second Level	Pathway ID	Pathway Name	p-Value	Adjusted p-Value	Enriched Genes
09100 Metabolism	09108 Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	3.250E-03	6.500E-03	ALDH1A1
Unclassified	Unclassified	hsa01100	Metabolic pathways	6.195E-02	6.195E-02	ALDH1A1

Human Diseases Associated with the Target Proteins of the Plant

Detailed Information of Human Diseases

ICD10 Disease Category	Disease Name	ICD10 Code	Associated Disease Targets (Association Ref: TTD database)

Data Section	Select to Download
1. General Info & Plant Usage & Geographical Distribution
2. Human Target Proteins
3. Target Gene Ontology
4. Target KEGG Pathway
5. Related Human Diseases