CMAUP Plant Collective Molecular Activities

List of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Target

Target Class	Target Proteins
Protein Kinase	MAPK1;

List of Human Cytochrome P450 Enzymes Affected by the Plant

Activity Range: ≤ 10μM
Click Gene ID to Access Activity Profile of Individual Enzyme

Cytochrome P450 Enzymes:	CYP3A4;

Detailed Information of Target Proteins

Show entries

Search:

Protein Class	Gene ID	Protein Name	Uniprot ID	Target ChEMBL ID
Cytochrome P450 family 3	CYP3A4	Cytochrome P450 3A4	P08684	CHEMBL340
Protein Kinase	MAPK1	MAP kinase ERK2	P28482	CHEMBL4040

Showing 1 to 2 of 2 entries

Previous1Next

Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)

Detailed Information of Enriched Gene Ontolgy

Show entries

Search:

GO Type	GO Category	Enriched GO Terms	p-Value	Adjusted p-Value	Enriched Genes
BP	GO:0008152; metabolic process	GO:0019858; cytosine metabolic process	2.071E-04	4.509E-01	MAPK1
BP	GO:0008152; metabolic process	GO:0009822; alkaloid catabolic process	3.106E-04	4.509E-01	CYP3A4
BP	GO:0051179; localization	GO:0072584; caveolin-mediated endocytosis	5.177E-04	4.697E-01	MAPK1
CC	Unclassified;	GO:0031143; pseudopodium	1.759E-03	7.095E-01	MAPK1
CC	GO:0044464; cell part	GO:0032839; dendrite cytoplasm	2.587E-03	8.744E-01	MAPK1
CC	GO:0044464; cell part	GO:0032838; plasma membrane bounded cell projection cytoplasm	6.925E-03	1.000E+00	MAPK1
CC	GO:0016020; membrane	GO:0005901; caveola	7.338E-03	1.000E+00	MAPK1
CC	GO:0044464; cell part	GO:0035578; azurophil granule lumen	9.400E-03	1.000E+00	MAPK1
CC	GO:0044464; cell part	GO:0043204; perikaryon	1.187E-02	1.000E+00	MAPK1
MF	GO:0003824; catalytic activity	GO:0070576; vitamin D 24-hydroxylase activity	3.106E-04	4.509E-01	CYP3A4

Showing 1 to 10 of 11 entries

Previous1 2Next

Enriched KEGG Pathways of Target Proteins (Activity≤10μM)

Top 10 KEGG Pathways (ordered by adjusted p-value)

Detailed Information of Enriched KEGG Pathways

Show entries

Search:

Pathway Category Top Level	Pathway Category Second Level	Pathway ID	Pathway Name	p-Value	Adjusted p-Value	Enriched Genes
09100 Metabolism	09103 Lipid metabolism	hsa00591	Linoleic acid metabolism	2.898E-03	1.792E-02	CYP3A4
09130 Environmental Information Processing	09132 Signal transduction	hsa04150	mTOR signaling pathway	5.991E-03	1.792E-02	MAPK1
09150 Organismal Systems	09156 Nervous system	hsa04730	Long-term depression	5.991E-03	1.792E-02	MAPK1
09150 Organismal Systems	09159 Environmental adaptation	hsa04713	Circadian entrainment	9.478E-03	1.792E-02	MAPK1
09160 Human Diseases	09161 Cancers	hsa05216	Thyroid cancer	2.898E-03	1.792E-02	MAPK1
09160 Human Diseases	09163 Neurodegenerative diseases	hsa05020	Prion diseases	3.497E-03	1.792E-02	MAPK1
09160 Human Diseases	09161 Cancers	hsa05223	Non-small cell lung cancer	5.592E-03	1.792E-02	MAPK1
09160 Human Diseases	09161 Cancers	hsa05214	Glioma	6.490E-03	1.792E-02	MAPK1
09160 Human Diseases	09167 Infectious diseases	hsa05133	Pertussis	7.486E-03	1.792E-02	MAPK1
Unclassified	Unclassified	hsa04320	Dorso-ventral axis formation	2.698E-03	1.792E-02	MAPK1

Showing 1 to 10 of 10 entries

Previous1Next

Human Diseases Associated with the Target Proteins of the Plant

Detailed Information of Human Diseases

Show entries

Search:

ICD10 Disease Category	Disease Name	ICD10 Code	Associated Disease Targets (Association Ref: TTD database)
No data available in table

Showing 0 to 0 of 0 entries

PreviousNext

Data Section	Select to Download
1. General Info & Plant Usage & Geographical Distribution
2. Human Target Proteins
3. Target Gene Ontology
4. Target KEGG Pathway
5. Related Human Diseases

Plant Name: Primula viscosa

Taxonomic Information:

Plant External Links:

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Collective Molecular Activities of the Plant

List of Human Proteins Collectively Targeted by the Plant

List of Human Cytochrome P450 Enzymes Affected by the Plant

Detailed Information of Target Proteins

Enrichment of Gene Ontology of Target Proteins (Activity≤10μM)

Detailed Information of Enriched Gene Ontolgy

Enriched KEGG Pathways of Target Proteins (Activity≤10μM)

Top 10 KEGG Pathways (ordered by adjusted p-value)

Detailed Information of Enriched KEGG Pathways

Human Diseases Associated with the Target Proteins of the Plant

Detailed Information of Human Diseases

>> Profiles of ingredients and activity landscape

>> Collective molecular activities profile at 10μM cutoff

>> Targets derived from weak experimental activities