Plant ID: NPO10810
Plant Latin Name: Acridocarpus vivy
Taxonomy Genus: Acridocarpus
Taxonomy Family: Malpighiaceae
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
n.a.
NPSR1; | |
TDP1; ALDH1A1; HPGD; | |
CA2; CA3; CA1; CA5B; CA4; CA6; CA12; CA14; CA9; CA5A; CA7; | |
KDM4E; | |
FUT7; | |
MAPT; LMNA; | |
SMN1;SMN2; |
Cytochrome P450 Enzymes: |
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Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|
Enzyme_unclassified | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
Enzyme_unclassified | ALDH1A1 | Aldehyde dehydrogenase 1A1 | P00352 | CHEMBL3577 |
Enzyme_unclassified | HPGD | 15-hydroxyprostaglandin dehydrogenase [NAD+] | P15428 | CHEMBL1293255 |
Lyase | CA2 | Carbonic anhydrase II | P00918 | CHEMBL205 |
Lyase | CA3 | Carbonic anhydrase III | P07451 | CHEMBL2885 |
Lyase | CA1 | Carbonic anhydrase I | P00915 | CHEMBL261 |
Lyase | CA5B | Carbonic anhydrase VB | Q9Y2D0 | CHEMBL3969 |
Lyase | CA4 | Carbonic anhydrase IV | P22748 | CHEMBL3729 |
Lyase | CA6 | Carbonic anhydrase VI | P23280 | CHEMBL3025 |
Lyase | CA12 | Carbonic anhydrase XII | O43570 | CHEMBL3242 |
Lyase | CA14 | Carbonic anhydrase XIV | Q9ULX7 | CHEMBL3510 |
Lyase | CA9 | Carbonic anhydrase IX | Q16790 | CHEMBL3594 |
Lyase | CA5A | Carbonic anhydrase VA | P35218 | CHEMBL4789 |
Lyase | CA7 | Carbonic anhydrase VII | P43166 | CHEMBL2326 |
Lysine demethylase | KDM4E | Lysine-specific demethylase 4D-like | B2RXH2 | CHEMBL1293226 |
Methyl-lysine/arginine binding protein | SMN1;SMN2 | Survival motor neuron protein | Q16637 | CHEMBL1293232 |
Peptide receptor (family A GPCR) | NPSR1 | Neuropeptide S receptor | Q6W5P4 | CHEMBL5162 |
Transferase | FUT7 | Alpha-(1,3)-fucosyltransferase 7 | Q11130 | CHEMBL3596077 |
Unclassified | MAPT | Microtubule-associated protein tau | P10636 | CHEMBL1293224 |
Unclassified | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
GO Type | GO Category | Enriched GO Terms | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|
MF | GO:0005488; binding | GO:0008270; zinc ion binding | 3.821E-09 | 8.320E-06 | CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
MF | GO:0003824; catalytic activity | GO:0004089; carbonate dehydratase activity | 1.377E-31 | 2.999E-27 | CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
BP | GO:0051179; localization | GO:0015701; bicarbonate transport | 7.633E-25 | 8.310E-21 | CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
BP | GO:0009987; cellular process | GO:0032849; positive regulation of cellular pH reduction | 3.375E-06 | 4.593E-03 | CA2, CA7 |
BP | GO:0008152; metabolic process | GO:0006730; one-carbon metabolic process | 4.450E-23 | 2.422E-19 | CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
MF | GO:0003824; catalytic activity | GO:0004064; arylesterase activity | 1.684E-05 | 1.930E-02 | CA1, CA2 |
CC | GO:0016020; membrane | GO:0016323; basolateral plasma membrane | 4.383E-05 | 4.544E-02 | CA2, CA4, CA9, HPGD |
BP | GO:0051179; localization | GO:2001225; regulation of chloride transport | 5.039E-05 | 4.988E-02 | CA2, CA7 |
Pathway Category Top Level | Pathway Category Second Level | Pathway ID | Pathway Name | p-Value | Adjusted p-Value | Enriched Genes |
---|---|---|---|---|---|---|
09100 Metabolism | 09102 Energy metabolism | hsa00910 | Nitrogen metabolism | 8.508E-31 | 1.531E-29 | CA12, CA1, CA3, CA5B, CA2, CA5A, CA4, CA7, CA6, CA9, CA14 |
09150 Organismal Systems | 09155 Excretory system | hsa04964 | Proximal tubule bicarbonate reclamation | 2.622E-04 | 2.359E-03 | CA2, CA4 |
09120 Genetic Information Processing | 09122 Translation | hsa03013 | RNA transport | 1.387E-02 | 8.322E-02 | SMN2, SMN1 |
09150 Organismal Systems | 09155 Excretory system | hsa04966 | Collecting duct acid secretion | 2.798E-02 | 9.620E-02 | CA2 |
09100 Metabolism | 09107 Glycan biosynthesis and metabolism | hsa00601 | Glycosphingolipid biosynthesis - lacto and neolacto series | 2.696E-02 | 9.620E-02 | FUT7 |
09150 Organismal Systems | 09154 Digestive system | hsa04971 | Gastric acid secretion | 7.493E-02 | 1.331E-01 | CA2 |
09100 Metabolism | 09108 Metabolism of cofactors and vitamins | hsa00830 | Retinol metabolism | 6.611E-02 | 1.331E-01 | ALDH1A1 |
09100 Metabolism | 09107 Glycan biosynthesis and metabolism | hsa00514 | Other types of O-glycan biosynthesis | 3.207E-02 | 9.620E-02 | FUT7 |
09150 Organismal Systems | 09154 Digestive system | hsa04976 | Bile secretion | 7.200E-02 | 1.331E-01 | CA2 |
09160 Human Diseases | 09165 Cardiovascular diseases | hsa05412 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) | 7.493E-02 | 1.331E-01 | LMNA |
ICD10 Disease Category | Disease Name | ICD10 Code | Associated Disease Targets (Association Ref: TTD database) |
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