Prescription Description
| Prescription ID | TCMFx214 |
| Pinyin Name | San Qi Xue Shang Ning Jiao Nang |
| Chinese Name | 三七血伤宁胶囊 |
| English Name | San Qi Xue Shang Ning Capsule |
| Function Description | 血证, 吐血, 咯血, 便血, 月经失调, 痛经, 闭经, 月经过多, 恶露不绝, 胃脘痛, 胁痛 |
| Indications | Stomach ache disorder, Menorrhagia disorder, Amenorrhea disorder, Dysmenorrhea disorder, Postpartum lochiorrhea disorder, Irregular menstruation |
| Disease ICD-11 Category |
SA51 [Stomach ache disorder (TM1), 胃脘痛 (TM1)
]; SB90 [Menorrhagia disorder (TM1), 月经过多 (TM1) ]; SB94 [Amenorrhea disorder (TM1), 闭经 (TM1) ]; SB96 [Dysmenorrhea disorder (TM1), 痛经 (TM1) ]; SC13 [Postpartum lochiorrhea disorder (TM1), 恶露不绝 (TM1) ]; GA20.3 [Abnormal regularity of uterine bleeding, 子宫出血周期异常 ]; |
| Human Tissues Associated with Indication | Uterus, Stomach |
| Reference | Chinese pharmacopoeia (2015) |
| Reference Book/link | ISBN 978-7-5067-7337-9 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1768 | Panax notoginseng | 三七 | TCMH1768 | ITSAO2360-14 |
| TCMH2646 | Rhizoma paridis | 重楼 | TCMH2646 | |
| TCMH222 | Aconitum carmichaelii | 草乌 | TCMH222 | ITSAH2410-14 |
| TCMH387 | Callicarpa macrophylla | 大叶紫珠 | TCMH387 | |
| TCMH1845 | Dioscorea batatas | 山药 | TCMH1845 | |
| TCMH851 | Veratrum japonicum | 黑紫藜芦 | TCMH851 | ITSAB1102-14 |
| TCMH183 | Dryobalanops aromatica | 冰片 | TCMH183 | GBVK4926-11 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT289 | TBXAS1 | Thromboxane-A synthase | Isomerase | P24557 |
| TCMT636 | POLA1 | DNA polymerase alpha subunit | Transferase | P09884 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1218 | Staphylococcus aureus |
| TCMT1221 | Human herpesvirus 4 |
| TCMT1229 | Enterococcus faecalis |
| TCMT1231 | Human herpesvirus 1 strain KOS |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1243 | Aspergillus flavus |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1438 | Plasmodium falciparum |
| TCMT1442 | Leishmania donovani |
| TCMT1454 | Bacillus subtilis |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1463 | Mycobacterium tuberculosis |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples