Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC1041	TCMT636	DNA polymerase alpha subunit	Homo sapiens	Ki: 830 (nM), Ref: 1705574
TCMC1041	TCMT17	DNA polymerase beta	Homo sapiens	Ki: 390 (nM), Ref: 1705574
TCMC2124	TCMT39	Phosphodiesterase 5A	Homo sapiens	IC50: 4703 (nM), Ref:
TCMC2124	TCMT289	Thromboxane-A synthase	Homo sapiens	IC50: 325 (nM), Ref:
TCMC614	TCMT151	Protein kinase C alpha	Homo sapiens	IC50: 9300 (nM), Ref: 9834166
TCMC916	TCMT161	Hydroxycarboxylic acid receptor 2	Homo sapiens	Ki: 4900 (nM), Ref: 21167710
TCMC732	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 5900 (nM), Ref: 21561086
TCMC804	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 2000 (nM), Ref: 21561086
TCMC1179	TCMT187	Androgen Receptor	Homo sapiens	IC50: 5900 (nM), Ref: 19592245 IC50: 5900 (nM), Ref: 19592245
TCMC1179	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 8 (nM), Ref: 20413308 IC50: 10000 (nM), Ref: 24345481 IC50: 8000 (nM), Ref: 26301554
TCMC1179	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1890 (nM), Ref: 22487176 Ki: 1880 (nM), Ref: 22487176
TCMC1179	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 8710 (nM), Ref: 22487176 Ki: 8800 (nM), Ref: 22487176
TCMC1179	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4130 (nM), Ref: 22487176 Ki: 4220 (nM), Ref: 22487176
TCMC1179	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7220 (nM), Ref: 22487176 Ki: 7330 (nM), Ref: 22487176
TCMC1179	TCMT127	Poly [ADP-ribose] polymerase-1	Homo sapiens	IC50: 1380.38 (nM), Ref: 23574272 IC50: 1400 (nM), Ref: 23574272
TCMC1179	TCMT128	Tankyrase-2	Homo sapiens	IC50: 147.91 (nM), Ref: 23574272 IC50: 140 (nM), Ref: 23574272
TCMC1179	TCMT129	Tankyrase-1	Homo sapiens	IC50: 323.59 (nM), Ref: 23574272 IC50: 320 (nM), Ref: 23574272 IC50: 323.59 (nM), Ref: 24116873 IC50: 330 (nM), Ref: 24116873
TCMC1063	TCMT277	Solute carrier organic anion transporter family member 1B3	Homo sapiens	Ki: 1430 (nM), Ref: 23396419 Ki: 4550 (nM), Ref: 23396419 Ki: 8290 (nM), Ref: 23396419 Ki: 1030 (nM), Ref: 23396419
TCMC1378	TCMT306	Matrix metalloproteinase-2	Homo sapiens	IC50: 8960 (nM), Ref: 22658537
TCMC1378	TCMT734	Matrix metalloproteinase 12	Homo sapiens	IC50: 8220 (nM), Ref: 22658537

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2124	TCMT1109	Reverse transcriptase	Human immunodeficiency virus 1	IC50: 50 (ug/ml), Ref: 1710653
TCMC2482	TCMT1246	Escherichia coli	Escherichia coli	MIC: 6.25 (ug/ml), Ref: 9392889
TCMC2482	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 6.25 (ug/ml), Ref: 9392889
TCMC2482	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 3.1 (ug/ml), Ref: 9392889
TCMC2482	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 3.1 (ug/ml), Ref: 9392889
TCMC2482	TCMT1251	Candida albicans	Candida albicans	MIC: 6.25 (ug/ml), Ref: 9392889
TCMC614	TCMT1454	Bacillus subtilis	Bacillus subtilis	IC50: 98.5 (ug/ml), Ref: 25981688
TCMC348	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MIC: 62 (ug/ml), Ref: 25813159
TCMC732	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 9 (ug/ml), Ref: 9748372
TCMC804	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 32 (ug/ml), Ref: 15387646 MIC: 62 (ug/ml), Ref: 23356207
TCMC804	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 25 (ug/ml), Ref: 22280816
TCMC804	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 32 (ug/ml), Ref: 15387646 MIC: 62 (ug/ml), Ref: 23356207
TCMC1063	TCMT1251	Candida albicans	Candida albicans	MIC: 1.56 (ug/ml), Ref: 3373231 MIC: 3.12 (ug/ml), Ref: 3373231 MIC: 6.25 (ug/ml), Ref: 3373231 MIC: 2 (ug/ml), Ref: 15921418
TCMC1063	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 25 (ug/ml), Ref: 3373231 MIC: 1 (ug/ml), Ref: 15921418
TCMC1063	TCMT1243	Aspergillus flavus	Aspergillus flavus	MIC: 100 (ug/ml), Ref: 3373231
TCMC1063	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 32 (ug/ml), Ref: 15921418
TCMC791	TCMT1221	Human herpesvirus 4	Human herpesvirus 4	IC50: 12.7 (nM), Ref: 17503850
TCMC1179	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2 (nM), Ref: 19097788