Component: Callicarpa macrophylla 大叶紫珠


Description of the Component

Component ID
TCMH387
Latin Name
Callicarpa macrophylla
English Name
Bigleaf beautyberry
Chinese Pinyin Name
Da Ye Zi Zhu
中文名
大叶紫珠
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx214 San Qi Xue Shang Ning Capsule 三七血伤宁胶囊
TCMFx1035 Zi Di Ning Xue Powder 紫地宁血散

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT151 PRKCA Protein kinase C alpha Kinase P17252
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT273 NR1H4 Bile acid receptor FXR Nuclear receptor Q96RI1
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT322 MMP13 Matrix metalloproteinase 13 Hydrolase P45452
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT734 MMP12 Matrix metalloproteinase 12 Hydrolase P39900
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1218 Staphylococcus aureus
TCMT1221 Human herpesvirus 4
TCMT1231 Human herpesvirus 1 strain KOS
TCMT1255 Human immunodeficiency virus 1
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1454 Bacillus subtilis
TCMT1463 Mycobacterium tuberculosis

Ingredient Structrues

Ingredient ID: TCMC923
Formula: C6H8O7

Ingredient ID: TCMC916
Formula: C9H8O2

Ingredient ID: TCMC804
Formula: C30H48O3

Ingredient ID: TCMC791
Formula: C40H56

Ingredient ID: TCMC7089
Formula: C20H32O3

Ingredient ID: TCMC614
Formula: C29H36O15

Ingredient ID: TCMC5860
Formula: C20H32O3

Ingredient ID: TCMC4738
Formula: C21H18O11

Ingredient ID: TCMC4290
Formula: C21H18O12

Ingredient ID: TCMC3233
Formula: C35H60O6

Ingredient ID: TCMC3117
Formula: C23H46O2

Ingredient ID: TCMC3032
Formula: C24H48O2

Ingredient ID: TCMC1920
Formula: C35H46O19

Ingredient ID: TCMC1378
Formula: C29H36O15

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC614 C29H36O15 Acetoside 624.21 -4.2978 3 -0.202 11 9 245.29 21 4 44 3
TCMC791 C40H56 Beta Carotene 536.44 8.935 5.86 14.734 0 0 0 20 2 40 1
TCMC804 C30H48O3 Betulinic Acid 456.36 2.3495 4.43 9.407 3 2 57.53 10 5 33 1
TCMC916 C9H8O2 Cinnamic Acid 148.05 0.1213 2.23 3.904 2 1 37.3 3 1 11 0
TCMC923 C6H8O7 Citric Acid 192.03 -1.395 1.35 -2.247 7 4 132.13 9 0 13 0
TCMC1378 C29H36O15 Isoacteoside 624.21 -4.2978 3 -0.202 11 9 245.29 21 4 44 3
TCMC1920 C35H46O19 Poliumoside 770.26 -5.5447 3.22 -0.607 15 11 304.21 26 5 54 3
TCMC3032 C24H48O2 Lignoceric Acid 367.3576057 -6.8795 3.88 11.641 2 0 40.13 22 0 26 2
TCMC3117 C23H46O2 Tricosanoic Acid 353.3419557 -6.5915 3.77 11.072 2 0 40.13 21 0 25 2
TCMC3233 C35H60O6 Alexandrin,Daucosterol,Eleutheroside A 576.4389896 -0.4469 4.65 10.487 6 4 99.38 9 5 41 1
TCMC4290 C21H18O12 Luteolin-7-O-Glucuronide,Luteolin-7-O-Β-D-Glucuronide 461.072001 -4.3003 2.45 -1.269 7 6 197.04 4 4 33 1
TCMC4738 C21H18O11 Apigenin-7-O-Β-D-Glucuronide 445.0770864 -4.0146 2.56 -0.711 10 5 176.81 4 4 32 0
TCMC5860 C20H32O3 Calliterpenone 320.2351449 0.3598 3.33 3.411 3 2 57.53 1 4 23 0
TCMC7089 C20H32O3 Calliterpenone 320.2351449 0.3598 3.33 3.411 3 2 57.53 1 4 23 0

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1. General Information of the Component  
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3. Putative Targets  
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5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)