NPASS Compound

Structure

CID109403 OpenBabel06191715462D 38 42 0 0 1 0 0 0 0 0999 V2000 3.4641 -4.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.5000 -3.8660 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8660 4.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.4641 3.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.4641 2.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5981 3.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4641 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8660 -2.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8660 -2.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4641 -3.0000 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 -0.5000 -3.8660 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5981 1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8660 -1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3301 -1.5000 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 -1.7321 3.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8660 -1.5000 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 2.5981 -1.5000 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0 -1.7321 2.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7321 -0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8660 0.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.3301 -2.5000 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 -2.5981 0.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7321 -1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.8660 1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 -3.0000 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 5.1962 -1.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 -4.7321 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 5.1962 -3.0000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.4641 -0.0000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -2.5981 -1.5000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.0000 2.0000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.8660 0.5000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.5000 -3.8660 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.8660 3.5000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5981 -2.5000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 1.7321 -1.0000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2 11 1 0 0 0 0 3 36 1 0 0 0 0 4 5 2 0 0 0 0 4 6 1 0 0 0 0 5 12 1 0 0 0 0 6 15 2 0 0 0 0 7 14 1 0 0 0 0 7 17 1 0 0 0 0 8 13 1 0 0 0 0 8 27 1 0 0 0 0 9 16 1 0 0 0 0 9 27 1 0 0 0 0 10 1 1 6 0 0 0 10 22 1 0 0 0 0 10 37 1 0 0 0 0 11 27 1 0 0 0 0 11 29 2 0 0 0 0 12 18 2 0 0 0 0 12 23 1 0 0 0 0 13 19 1 0 0 0 0 13 24 2 0 0 0 0 14 22 1 0 0 0 0 14 28 1 6 0 0 0 15 18 1 0 0 0 0 15 36 1 0 0 0 0 16 19 1 0 0 0 0 16 38 1 1 0 0 0 17 37 1 0 0 0 0 17 38 1 1 0 0 0 18 25 1 0 0 0 0 19 26 2 0 0 0 0 20 21 2 0 0 0 0 20 23 1 0 0 0 0 20 24 1 0 0 0 0 21 25 1 0 0 0 0 21 26 1 0 0 0 0 22 30 1 6 0 0 0 23 31 2 0 0 0 0 24 32 1 0 0 0 0 25 33 2 0 0 0 0 26 34 1 0 0 0 0 27 35 1 1 0 0 0 M END $$$$

Physi-Chem Properties

Molecular Weight:	527.18
Volume:	507.937
LogP:	2.448
LogD:	1.441
LogS:	-3.0
# Rotatable Bonds:	4
TPSA:	192.16
# H-Bond Aceptor:	11
# H-Bond Donor:	8
# Rings:	5
# Heavy Atoms:	11

MedChem Properties

QED Drug-Likeness Score:	0.182
Synthetic Accessibility Score:	4.968
Fsp3:	0.37
Lipinski Rule-of-5:	Rejected
Pfizer Rule:	Accepted
GSK Rule:	Rejected
BMS Rule:	0
Golden Triangle Rule:	Rejected
Chelating Alert:	0
PAINS Alert:	0

ADMET Properties (ADMETlab2.0)

ADMET: Absorption

Caco-2 Permeability:	-5.822
MDCK Permeability:	5.57839848625008e-06
Pgp-inhibitor:	0.056
Pgp-substrate:	0.999
Human Intestinal Absorption (HIA):	0.495
20% Bioavailability (F20%):	0.01
30% Bioavailability (F30%):	0.013

ADMET: Distribution

Blood-Brain-Barrier Penetration (BBB):	0.006
Plasma Protein Binding (PPB):	93.19788360595703%
Volume Distribution (VD):	0.804
Pgp-substrate:	11.07198429107666%

ADMET: Metabolism

CYP1A2-inhibitor:	0.535
CYP1A2-substrate:	0.894
CYP2C19-inhibitor:	0.016
CYP2C19-substrate:	0.096
CYP2C9-inhibitor:	0.04
CYP2C9-substrate:	0.584
CYP2D6-inhibitor:	0.016
CYP2D6-substrate:	0.192
CYP3A4-inhibitor:	0.09
CYP3A4-substrate:	0.201

ADMET: Excretion

Clearance (CL):	10.755
Half-life (T1/2):	0.639

ADMET: Toxicity

hERG Blockers:	0.019
Human Hepatotoxicity (H-HT):	0.621
Drug-inuced Liver Injury (DILI):	0.944
AMES Toxicity:	0.758
Rat Oral Acute Toxicity:	0.012
Maximum Recommended Daily Dose:	0.523
Skin Sensitization:	0.433
Carcinogencity:	0.86
Eye Corrosion:	0.003
Eye Irritation:	0.077
Respiratory Toxicity:	0.912

Download Data

Data Type	Select
General Info & Identifiers & Properties
Structure MOL file
Source Organisms
Biological Activities
Similar NPs/Drugs

Natural Product: NPC109403

Natural Product ID:	NPC109403
*Common Name:**	Daunorubicin
IUPAC Name:	(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
Synonyms:	Cerubidine; Daunorubicin; Daunoxome
Standard InCHIKey:	STQGQHZAVUOBTE-VGBVRHCVSA-N
Standard InCHI:	InChI=1S/C27H29NO10/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3/t10-,14-,16-,17-,22+,27-/m0/s1
SMILES:	COc1cccc2c1C(=O)c1c(C2=O)c(O)c2c(c1O)[C@@H](O[C@H]1C[C@H](N)[C@@H]([C@@H](O1)C)O)C[C@](C2)(O)C(=O)C
Synthetic Gene Cluster:	BGC0000217;
ChEMBL Identifier:	CHEMBL178
PubChem CID:	30323
Chemical Classification:**	CHEMONTID:0000000 [Organic compounds] [CHEMONTID:0000261] Phenylpropanoids and polyketides [CHEMONTID:0002106] Anthracyclines

*Note: the InCHIKey will be temporarily assigned as the "Common Name" if no IUPAC name or alternative short name is available.
**Note: the Chemical Classification was calculated by NPClassifier Version 1.5. Reference: PMID:34662515.

Species Source

Organism ID	Organism Name	Taxonomy Level	Family	SuperKingdom	Isolation Part	Collection Location	Collection Time	Reference
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10344559]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10344578]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10348041]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10604756]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10695669]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10724004]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[10994816]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[11099231]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[11132958]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[11374972]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[11473415]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[14738393]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	Australian	n.a.	PMID[15497950]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[15813185]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[15844966]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[15974616]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[16180833]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[1666120]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[16724845]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[16830891]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[16872146]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17125235]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17315965]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17551212]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17608531]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17844998]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17887721]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[17917237]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[18044841]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[18081255]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	Indonesian	n.a.	PMID[18081255]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[18205372]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[18327911]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	Northwest Territories, Canada	1995	PMID[18327911]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[18666798]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[18776684]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[19007176]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[19129624]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[19191549]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[19856955]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[19883065]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[20092333]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[20545334]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[20836523]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21028889]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21028891]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	mycelium	n.a.	PMID[21090727]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21314175]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	mycelium	n.a.	PMID[21639131]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21728289]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	latex	n.a.	PMID[21751787]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21807523]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[21873059]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	latex	n.a.	PMID[21879726]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	mycelium	n.a.	PMID[22145663]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[22574670]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[22583058]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[22591466]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[22758660]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[22775474]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[23387796]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[23662937]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[24592993]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[24754815]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[24878306]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[24964393]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[25211234]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[25455147]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[25495422]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[25537064]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[25918793]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[25934225]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[26035239]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[26465675]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[26798949]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[26905826]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[31013087]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[31298537]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[31894983]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[32298122]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[8501018]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	mycelium	n.a.	PMID[8784423]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[8931733]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[8982334]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[9031666]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[9031676]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[9066767]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[9066768]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[9186568]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	n.a.	n.a.	PMID[9531983]
NPO30376	Streptomyces sp.	Species	Streptomycetaceae	Bacteria	n.a.	mycelium	n.a.	PMID[9711246]

☑ Note for Reference:
In addition to directly collecting NP source organism data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated them from below databases:
☉ UNPD: Universal Natural Products Database [PMID: 23638153].
☉ StreptomeDB: a database of streptomycetes natural products [PMID: 33051671].
☉ TM-MC: a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine [PMID: 26156871].
☉ TCM@Taiwan: a Traditional Chinese Medicine database [PMID: 21253603].
☉ TCMID: a Traditional Chinese Medicine database [PMID: 29106634].
☉ TCMSP: The traditional Chinese medicine systems pharmacology database and analysis platform [PMID: 24735618].
☉ HerDing: a herb recommendation system to treat diseases using genes and chemicals [PMID: 26980517].
☉ MetaboLights: a metabolomics database [PMID: 27010336].
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

NP Quantity Composition/Concentration

Organism ID	NP ID	Organism Material Preparation	Organism Part	NP Quantity (Standard)	NP Quantity (Minimum)	NP Quantity (Maximum)	Quantity Unit	Reference

☑ Note for Reference:
In addition to directly collecting NP quantitative data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated NP quantitative records for specific NP domains (e.g., NPS from foods or herbs) from domain-specific databases. These databases include:
☉ DUKE: Dr. Duke's Phytochemical and Ethnobotanical Databases.
☉ PHENOL EXPLORER: is the first comprehensive database on polyphenol content in foods [PMID: 24103452], its homepage can be accessed at here.
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

Biological Activity

Activity Type	# Activity
AC50	9
EC50	5
ED50	12
GI50	11
IC50	181
Kd	1
Ki	5
MIC	9
Others	890
Potency	130

Activity Type	# Activity
Cell Line	303
CELL-LINE	5
Individual Protein	101
NON-MOLECULAR	28
NUCLEIC-ACID	1
Organism	604
Others	157
PHENOTYPE	26
Protein-Protein Interaction	7
SINGLE PROTEIN	3
TISSUE	1
Uncleic Acid	17

Target ID	Target Type	Target Name	Target Organism	Activity Type	Activity Relation	Value	Unit	Reference
NPT153	Individual Protein	Androgen Receptor	Homo sapiens	Potency	n.a.	2131.4	nM	PubChem BioAssay data set
NPT153	Individual Protein	Androgen Receptor	Homo sapiens	Potency	n.a.	14960.1	nM	PubChem BioAssay data set
NPT152	Individual Protein	Nuclear factor erythroid 2-related factor 2	Homo sapiens	Potency	n.a.	26601.1	nM	PubChem BioAssay data set
NPT106	Individual Protein	Peroxisome proliferator-activated receptor delta	Homo sapiens	Potency	n.a.	133.3	nM	PubChem BioAssay data set
NPT153	Individual Protein	Androgen Receptor	Homo sapiens	Potency	n.a.	952.1	nM	PubChem BioAssay data set
NPT106	Individual Protein	Peroxisome proliferator-activated receptor delta	Homo sapiens	Potency	n.a.	749.7	nM	PubChem BioAssay data set
NPT168	Cell Line	P388	Mus musculus	T/C	=	130.0	%	PMID[474427]
NPT137	Cell Line	L1210	Mus musculus	ED50	=	0.66	uM	PMID[474427]
NPT137	Cell Line	L1210	Mus musculus	ED50	=	0.33	uM	PMID[474427]
NPT116	Cell Line	HL-60	Homo sapiens	IC50	=	5.0	nM	PMID[474428]
NPT116	Cell Line	HL-60	Homo sapiens	AC50	=	40.0	nM	PMID[474428]
NPT116	Cell Line	HL-60	Homo sapiens	IC50	=	1500.0	nM	PMID[474428]
NPT116	Cell Line	HL-60	Homo sapiens	AC50	=	10000.0	nM	PMID[474428]
NPT116	Cell Line	HL-60	Homo sapiens	IC50	=	40.0	nM	PMID[474428]
NPT137	Cell Line	L1210	Mus musculus	IC50	=	33.0	nM	PMID[474429]
NPT1178	Cell Line	KB 3-1	Homo sapiens	IC50	=	7.0	nM	PMID[474429]
NPT91	Cell Line	KB	Homo sapiens	IC50	=	2070.0	nM	PMID[474429]
NPT3877	Cell Line	NSCLC	Homo sapiens	IC50	=	3.9	nM	PMID[474430]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	39.0	nM	PMID[474430]
NPT397	Cell Line	NCI-H460	Homo sapiens	IC50	=	3.5	nM	PMID[474430]
NPT319	Cell Line	B16	Mus musculus	IC50	=	9.2	nM	PMID[474430]
NPT4264	Cell Line	Lewis lung carcinoma cell line		IC50	=	61.0	nM	PMID[474430]
NPT3890	Cell Line	YOSHIDA	Rattus norvegicus	IC50	=	7.4	nM	PMID[474430]
NPT4265	Cell Line	WALKER	Rattus norvegicus	IC50	=	47.0	nM	PMID[474430]
NPT2185	Cell Line	OCI-AML2	Homo sapiens	Cytotoxicity	=	0.001	ug ml-1	PMID[474432]
NPT2185	Cell Line	OCI-AML2	Homo sapiens	Cytotoxicity	=	0.52	ug ml-1	PMID[474432]
NPT2185	Cell Line	OCI-AML2	Homo sapiens	Cytotoxicity	=	0.43	ug ml-1	PMID[474432]
NPT1868	Cell Line	L1210 (1565)		T/C	=	290.0	%	PMID[474433]
NPT168	Cell Line	P388	Mus musculus	T/C	=	143.0	%	PMID[474433]
NPT568	Individual Protein	Matrix metalloproteinase-2	Homo sapiens	IC50	=	1900.0	nM	PMID[474434]
NPT4266	Individual Protein	NADH-ubiquinone oxidoreductase chain 4	Homo sapiens	Activity	=	0.15	units ml-1	PMID[474435]
NPT4266	Individual Protein	NADH-ubiquinone oxidoreductase chain 4	Homo sapiens	IC10	=	2.0	uM	PMID[474435]
NPT1161	Cell Line	CHO	Cricetulus griseus	Log CR	=	1.88	n.a.	PMID[474436]
NPT319	Cell Line	B16	Mus musculus	EC50	=	160.0	nM	PMID[474437]
NPT404	Cell Line	CCRF-CEM	Homo sapiens	Log CR	=	1.2	n.a.	PMID[474438]
NPT83	Cell Line	MCF7	Homo sapiens	ID50	=	329.0	ng ml-1	PMID[474439]
NPT2046	Cell Line	EVSA-T	Homo sapiens	ID50	=	48.0	ng ml-1	PMID[474439]
NPT1183	Cell Line	WiDr	Homo sapiens	ID50	=	38.0	ng ml-1	PMID[474439]
NPT458	Cell Line	IGROV-1	Homo sapiens	ID50	=	113.0	ng ml-1	PMID[474439]
NPT376	Cell Line	A498	Homo sapiens	ID50	=	487.0	ng ml-1	PMID[474439]
NPT405	Cell Line	NCI-H226	Homo sapiens	ID50	=	243.0	ng ml-1	PMID[474439]
NPT2844	Cell Line	MES-SA	Homo sapiens	IC50	=	21.0	nM	PMID[474442]
NPT2829	Cell Line	MES-SA/DxS	Homo sapiens	IC50	=	2000.0	nM	PMID[474442]
NPT2829	Cell Line	MES-SA/DxS	Homo sapiens	IC50	=	14.0	nM	PMID[474442]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	60.0	nM	PMID[474443]
NPT378	Cell Line	NCI/ADR-RES	Homo sapiens	IC50	=	2000.0	nM	PMID[474443]
NPT168	Cell Line	P388	Mus musculus	IC50	=	3.0	nM	PMID[474444]
NPT404	Cell Line	CCRF-CEM	Homo sapiens	ID50	=	0.04	uM	PMID[474446]
NPT144	Individual Protein	Telomerase reverse transcriptase	Homo sapiens	Inhibition	<	50.0	%	PMID[474448]
NPT4267	Cell Line	MEXF989	Homo sapiens	IC70	=	0.26	uM	PMID[474450]
NPT4268	Cell Line	LXFL 529/11		IC90	=	30.0	nM	PMID[474450]
NPT2473	Cell Line	MDA-MB-361	Homo sapiens	IC50	=	17.0	nM	PMID[474452]
NPT2473	Cell Line	MDA-MB-361	Homo sapiens	IC50	=	36.0	nM	PMID[474452]
NPT2473	Cell Line	MDA-MB-361	Homo sapiens	IC50	=	21.0	nM	PMID[474452]
NPT137	Cell Line	L1210	Mus musculus	IC50	=	40.0	nM	PMID[474453]
NPT1178	Cell Line	KB 3-1	Homo sapiens	IC50	=	7.0	nM	PMID[474453]
NPT91	Cell Line	KB	Homo sapiens	IC50	=	2070.0	nM	PMID[474453]
NPT2844	Cell Line	MES-SA	Homo sapiens	IC50	=	70.0	nM	PMID[474453]
NPT2844	Cell Line	MES-SA	Homo sapiens	IC50	=	3000.0	nM	PMID[474453]
NPT91	Cell Line	KB	Homo sapiens	Resistance factor	=	295.7	n.a.	PMID[474453]
NPT1506	Cell Line	SK-MES-1	Homo sapiens	Resistance factor	=	42.8	n.a.	PMID[474453]
NPT168	Cell Line	P388	Mus musculus	Total dose	=	4.0	mg kg-1	PMID[474454]
NPT168	Cell Line	P388	Mus musculus	Mortality	=	20.0	day	PMID[474454]
NPT168	Cell Line	P388	Mus musculus	Change in body weight	=	0.3	g mouse-1	PMID[474454]
NPT168	Cell Line	P388	Mus musculus	Median day of death	=	18.0	n.a.	PMID[474454]
NPT168	Cell Line	P388	Mus musculus	ILS	=	63.0	%	PMID[474454]
NPT168	Cell Line	P388	Mus musculus	Survivors	=	0.0	n.a.	PMID[474454]
NPT168	Cell Line	P388	Mus musculus	Mortality	=	27.0	day	PMID[474454]
NPT168	Cell Line	P388	Mus musculus	Change in body weight	=	1.4	g mouse-1	PMID[474454]
NPT168	Cell Line	P388	Mus musculus	Median day of death	=	19.5	n.a.	PMID[474454]
NPT168	Cell Line	P388	Mus musculus	ILS	=	79.0	%	PMID[474454]
NPT404	Cell Line	CCRF-CEM	Homo sapiens	ID50	=	0.04	uM	PMID[474456]
NPT168	Cell Line	P388	Mus musculus	T/C	=	130.0	%	PMID[474457]
NPT137	Cell Line	L1210	Mus musculus	ED50	=	0.66	uM	PMID[474457]
NPT137	Cell Line	L1210	Mus musculus	ED50	=	0.33	uM	PMID[474457]
NPT137	Cell Line	L1210	Mus musculus	IC50	=	30.0	nM	PMID[474458]
NPT137	Cell Line	L1210	Mus musculus	IC50	=	0.038	n.a.	PMID[474459]
NPT137	Cell Line	L1210	Mus musculus	IC50	=	0.028	n.a.	PMID[474459]
NPT139	Cell Line	HT-29	Homo sapiens	IC50	=	0.35	n.a.	PMID[474459]
NPT139	Cell Line	HT-29	Homo sapiens	IC50	=	0.027	n.a.	PMID[474459]
NPT137	Cell Line	L1210	Mus musculus	Cytotoxicity	=	0.02	ug ml-1	PMID[474461]
NPT143	Individual Protein	DNA topoisomerase I	Homo sapiens	Ka1	=	980.0	n.a.	PMID[474462]
NPT143	Individual Protein	DNA topoisomerase I	Homo sapiens	Ratio	=	1.4	n.a.	PMID[474462]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	60.0	nM	PMID[474463]
NPT378	Cell Line	NCI/ADR-RES	Homo sapiens	IC50	=	2000.0	nM	PMID[474463]
NPT168	Cell Line	P388	Mus musculus	T/C	=	160.0	n.a.	PMID[474464]
NPT15	Cell Line	Jurkat	Homo sapiens	IC50	=	82.6	nM	PMID[474465]
NPT15	Cell Line	Jurkat	Homo sapiens	IC75	=	182.2	nM	PMID[474465]
NPT111	Cell Line	K562	Homo sapiens	IC50	=	15.0	nM	PMID[474466]
NPT111	Cell Line	K562	Homo sapiens	IC50	>	5000.0	nM	PMID[474466]
NPT111	Cell Line	K562	Homo sapiens	Ratio IC50	=	333.0	n.a.	PMID[474466]
NPT111	Cell Line	K562	Homo sapiens	Activity	=	70.0	%	PMID[474466]
NPT111	Cell Line	K562	Homo sapiens	Activity	=	30.0	%	PMID[474466]
NPT165	Cell Line	HeLa	Homo sapiens	IC50	=	2960.0	nM	PMID[474467]
NPT400	Cell Line	MDA-MB-435	Homo sapiens	IC50	=	977.0	nM	PMID[474468]
NPT400	Cell Line	MDA-MB-435	Homo sapiens	IC50	=	129.0	nM	PMID[474468]
NPT400	Cell Line	MDA-MB-435	Homo sapiens	IC50	=	79.0	nM	PMID[474468]
NPT552	Cell Line	P388/ADR	Mus musculus	IC50	=	2111.0	nM	PMID[474468]
NPT168	Cell Line	P388	Mus musculus	IC50	=	25.0	nM	PMID[474468]
NPT400	Cell Line	MDA-MB-435	Homo sapiens	Ratio IC50	=	7.6	n.a.	PMID[474468]
NPT552	Cell Line	P388/ADR	Mus musculus	IC50	=	106.0	nM	PMID[474468]
NPT552	Cell Line	P388/ADR	Mus musculus	IC50	=	40.0	nM	PMID[474468]
NPT168	Cell Line	P388	Mus musculus	Ratio IC50	=	20.0	n.a.	PMID[474468]
NPT168	Cell Line	P388	Mus musculus	Ratio IC50	=	53.0	n.a.	PMID[474468]
NPT148	Cell Line	HCT-15	Homo sapiens	IC50	>	400.0	nM	PMID[474469]
NPT369	Cell Line	ACHN	Homo sapiens	IC50	=	63.0	nM	PMID[474469]
NPT1396	Cell Line	NCI-H69	Homo sapiens	IC50	=	100.0	nM	PMID[474469]
NPT404	Cell Line	CCRF-CEM	Homo sapiens	TCS50	=	62.0	nM	PMID[474470]
NPT83	Cell Line	MCF7	Homo sapiens	TCS50	=	140.0	nM	PMID[474470]
NPT111	Cell Line	K562	Homo sapiens	TCS50	=	230.0	nM	PMID[474470]
NPT2468	Cell Line	G-361	Homo sapiens	TCS50	=	670.0	nM	PMID[474470]
NPT165	Cell Line	HeLa	Homo sapiens	TCS50	=	670.0	nM	PMID[474470]
NPT307	Cell Line	HOS	Homo sapiens	TCS50	=	330.0	nM	PMID[474470]
NPT179	Cell Line	A2780	Homo sapiens	IC50	=	117.49	nM	PMID[474472]
NPT459	Individual Protein	Human immunodeficiency virus type 1 reverse transcriptase	Human immunodeficiency virus 1	IC50	=	125.0	ug.mL-1	PMID[474475]
NPT168	Cell Line	P388	Mus musculus	T/C	=	177.0	%	PMID[474477]
NPT168	Cell Line	P388	Mus musculus	T/C	=	190.0	%	PMID[474477]
NPT168	Cell Line	P388	Mus musculus	T/C	=	168.0	%	PMID[474477]
NPT165	Cell Line	HeLa	Homo sapiens	Activity	=	13.0	%	PMID[474477]
NPT165	Cell Line	HeLa	Homo sapiens	Activity	=	48.0	%	PMID[474477]
NPT165	Cell Line	HeLa	Homo sapiens	Activity	=	123.0	%	PMID[474477]
NPT165	Cell Line	HeLa	Homo sapiens	ID50	=	12.5	ng/ml	PMID[474477]
NPT168	Cell Line	P388	Mus musculus	ID50	=	9.5	ng/ml	PMID[474477]
NPT168	Cell Line	P388	Mus musculus	ID50	=	750.0	ng/ml	PMID[474477]
NPT886	Cell Line	NIH3T3	Mus musculus	IC50	=	1010.0	nM	PMID[474479]
NPT886	Cell Line	NIH3T3	Mus musculus	Ratio IC50	=	23.0	n.a.	PMID[474479]
NPT139	Cell Line	HT-29	Homo sapiens	IC50	=	133.0	nM	PMID[474481]
NPT139	Cell Line	HT-29	Homo sapiens	IZ	=	5.0	mm	PMID[474481]
NPT168	Cell Line	P388	Mus musculus	IC50	=	28.0	nM	PMID[474481]
NPT168	Cell Line	P388	Mus musculus	IZ	=	20.0	mm	PMID[474481]
NPT168	Cell Line	P388	Mus musculus	IZ	=	12.5	mm	PMID[474481]
NPT168	Cell Line	P388	Mus musculus	IZ	=	10.0	mm	PMID[474481]
NPT459	Individual Protein	Human immunodeficiency virus type 1 reverse transcriptase	Human immunodeficiency virus 1	IC50	=	125.0	ug.mL-1	PMID[474482]
NPT116	Cell Line	HL-60	Homo sapiens	AC50	=	100.0	nM	PMID[474485]
NPT116	Cell Line	HL-60	Homo sapiens	AC50	=	38000.0	nM	PMID[474485]
NPT82	Cell Line	MDA-MB-231	Homo sapiens	GI50	=	20.0	nM	PMID[474488]
NPT82	Cell Line	MDA-MB-231	Homo sapiens	TGI	=	120.0	nM	PMID[474488]
NPT82	Cell Line	MDA-MB-231	Homo sapiens	LC50	=	860.0	nM	PMID[474488]
NPT81	Cell Line	A549	Homo sapiens	GI50	=	80.0	nM	PMID[474488]
NPT81	Cell Line	A549	Homo sapiens	TGI	=	170.0	nM	PMID[474488]
NPT81	Cell Line	A549	Homo sapiens	LC50	=	350.0	nM	PMID[474488]
NPT139	Cell Line	HT-29	Homo sapiens	GI50	=	70.0	nM	PMID[474488]
NPT139	Cell Line	HT-29	Homo sapiens	TGI	=	330.0	nM	PMID[474488]
NPT139	Cell Line	HT-29	Homo sapiens	LC50	>	17200.0	nM	PMID[474488]
NPT91	Cell Line	KB	Homo sapiens	IC50	=	0.22	ug.mL-1	PMID[474489]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	0.33	ug.mL-1	PMID[474489]
NPT111	Cell Line	K562	Homo sapiens	IC50	=	0.45	ug.mL-1	PMID[474489]
NPT407	Cell Line	COLO 205	Homo sapiens	IC50	=	0.5	ug.mL-1	PMID[474489]
NPT111	Cell Line	K562	Homo sapiens	IC50	=	15.2	ug.mL-1	PMID[474489]
NPT71	Cell Line	HEK293	Homo sapiens	Activity	=	82.0	%	PMID[474490]
NPT91	Cell Line	KB	Homo sapiens	IC50	=	640.0	nM	PMID[474491]
NPT83	Cell Line	MCF7	Homo sapiens	Activity	=	30.0	%	PMID[474493]
NPT397	Cell Line	NCI-H460	Homo sapiens	Activity	=	15.0	%	PMID[474493]
NPT395	Cell Line	SF-268	Homo sapiens	Activity	=	16.0	%	PMID[474493]
NPT83	Cell Line	MCF7	Homo sapiens	GI50	=	860.0	nM	PMID[474493]
NPT397	Cell Line	NCI-H460	Homo sapiens	GI50	=	380.0	nM	PMID[474493]
NPT395	Cell Line	SF-268	Homo sapiens	GI50	=	600.0	nM	PMID[474493]
NPT1329	Cell Line	Detroit 551	Homo sapiens	GI50	=	1770.0	nM	PMID[474493]
NPT83	Cell Line	MCF7	Homo sapiens	RatioGI50	=	2.06	n.a.	PMID[474493]
NPT397	Cell Line	NCI-H460	Homo sapiens	RatioGI50	=	4.66	n.a.	PMID[474493]
NPT395	Cell Line	SF-268	Homo sapiens	RatioGI50	=	2.95	n.a.	PMID[474493]
NPT111	Cell Line	K562	Homo sapiens	GI50	=	7.4	nM	PMID[474493]
NPT111	Cell Line	K562	Homo sapiens	RatioGI50	=	239.0	n.a.	PMID[474493]
NPT46	Individual Protein	Thyroid hormone receptor beta-1	Homo sapiens	Potency	=	11220.2	nM	PMID[474498]
NPT46	Individual Protein	Thyroid hormone receptor beta-1	Homo sapiens	Potency	=	22387.2	nM	PMID[474499]
NPT47	Individual Protein	ATP-dependent DNA helicase Q1	Homo sapiens	Potency	=	31622.8	nM	PMID[474498]
NPT149	Individual Protein	Endoplasmic reticulum-associated amyloid beta-peptide-binding protein	Homo sapiens	Potency	=	31622.8	nM	PMID[474498]
NPT47	Individual Protein	ATP-dependent DNA helicase Q1	Homo sapiens	Potency	=	28183.8	nM	PMID[474499]
NPT48	Individual Protein	Lysine-specific demethylase 4D-like	Homo sapiens	Potency	=	35481.3	nM	PMID[474498]
NPT1197	Individual Protein	Huntingtin	Homo sapiens	Potency	=	2238.7	nM	PMID[474499]
NPT1038	Individual Protein	Histone-lysine N-methyltransferase MLL	Homo sapiens	Potency	=	28183.8	nM	PMID[474499]
NPT49	Individual Protein	DNA-(apurinic or apyrimidinic site) lyase	Homo sapiens	Potency	=	10000.0	nM	PMID[474499]
NPT50	Individual Protein	Tyrosyl-DNA phosphodiesterase 1	Homo sapiens	Potency	=	15848.9	nM	PMID[474499]
NPT50	Individual Protein	Tyrosyl-DNA phosphodiesterase 1	Homo sapiens	Potency	=	22387.2	nM	PMID[474498]
NPT46	Individual Protein	Thyroid hormone receptor beta-1	Homo sapiens	Potency	=	31622.8	nM	PMID[474498]
NPT46	Individual Protein	Thyroid hormone receptor beta-1	Homo sapiens	Potency	=	44668.4	nM	PMID[474499]
NPT51	Individual Protein	Microtubule-associated protein tau	Homo sapiens	Potency	=	4466.8	nM	PMID[474498]
NPT51	Individual Protein	Microtubule-associated protein tau	Homo sapiens	Potency	=	5011.9	nM	PMID[474499]
NPT531	Individual Protein	Nuclear receptor ROR-gamma	Mus musculus	Potency	=	6309.6	nM	PMID[474499]
NPT531	Individual Protein	Nuclear receptor ROR-gamma	Mus musculus	Potency	=	63.1	nM	PMID[474498]
NPT58	Individual Protein	Bloom syndrome protein	Homo sapiens	Potency	=	16231.3	nM	PMID[474498]
NPT53	Individual Protein	4'-phosphopantetheinyl transferase ffp	Bacillus subtilis	Potency	=	3162.3	nM	PMID[474498]
NPT583	Individual Protein	Inositol monophosphatase 1	Rattus norvegicus	Potency	=	12589.3	nM	PMID[474498]
NPT442	Individual Protein	Ferritin light chain	Equus caballus	Potency	=	17782.8	nM	PMID[474499]
NPT51	Individual Protein	Microtubule-associated protein tau	Homo sapiens	Potency	=	25118.9	nM	PMID[474499]
NPT51	Individual Protein	Microtubule-associated protein tau	Homo sapiens	Potency	=	25118.9	nM	PMID[474498]
NPT157	Individual Protein	Breast cancer type 1 susceptibility protein	Homo sapiens	Potency	=	12589.3	nM	PMID[474498]
NPT282	Individual Protein	MAP kinase ERK2	Homo sapiens	Potency	=	31622.8	nM	PMID[474498]
NPT55	Individual Protein	Putative fructose-1,6-bisphosphate aldolase	Giardia intestinalis	Potency	=	22334.2	nM	PMID[474498]
NPT55	Individual Protein	Putative fructose-1,6-bisphosphate aldolase	Giardia intestinalis	Potency	=	14091.9	nM	PMID[474499]
NPT150	Individual Protein	Anthrax lethal factor	Bacillus anthracis	Potency	=	31622.8	nM	PMID[474498]
NPT531	Individual Protein	Nuclear receptor ROR-gamma	Mus musculus	Potency	=	2818.4	nM	PMID[474499]
NPT531	Individual Protein	Nuclear receptor ROR-gamma	Mus musculus	Potency	=	7943.3	nM	PMID[474498]
NPT539	Individual Protein	Cellular tumor antigen p53	Homo sapiens	Potency	=	15848.9	nM	PMID[474498]
NPT539	Individual Protein	Cellular tumor antigen p53	Homo sapiens	Potency	=	31622.8	nM	PMID[474498]
NPT58	Individual Protein	Bloom syndrome protein	Homo sapiens	Potency	=	14125.4	nM	PMID[474498]
NPT58	Individual Protein	Bloom syndrome protein	Homo sapiens	Potency	=	28183.8	nM	PMID[474499]
NPT109	Individual Protein	Cytochrome P450 3A4	Homo sapiens	Potency	=	31622.8	nM	PMID[474498]
NPT65	Cell Line	HepG2	Homo sapiens	Activity	=	2.0	%	PMID[474500]
NPT139	Cell Line	HT-29	Homo sapiens	Activity	=	11.0	%	PMID[474500]
NPT83	Cell Line	MCF7	Homo sapiens	Activity	=	2.0	%	PMID[474500]
NPT65	Cell Line	HepG2	Homo sapiens	Activity	=	0.7	%	PMID[474500]
NPT139	Cell Line	HT-29	Homo sapiens	Activity	=	2.1	%	PMID[474500]
NPT83	Cell Line	MCF7	Homo sapiens	Activity	=	0.6	%	PMID[474500]
NPT189	Cell Line	Vero	Chlorocebus aethiops	IC50	=	2500.0	nM	PMID[474500]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	5500.0	nM	PMID[474500]
NPT65	Cell Line	HepG2	Homo sapiens	IC50	=	700.0	nM	PMID[474500]
NPT139	Cell Line	HT-29	Homo sapiens	IC50	=	400.0	nM	PMID[474500]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	0.5	ug.mL-1	PMID[474501]
NPT443	Individual Protein	Histone acetyltransferase GCN5	Homo sapiens	Potency	n.a.	316.2	nM	PMID[474498]
NPT62	Individual Protein	6-phospho-1-fructokinase	Trypanosoma brucei	Potency	n.a.	7943.3	nM	PMID[474499]
NPT5	Individual Protein	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Homo sapiens	Potency	n.a.	15848.9	nM	PMID[474499]
NPT1139	Individual Protein	Arachidonate 15-lipoxygenase, type II	Homo sapiens	Potency	n.a.	12589.3	nM	PMID[474498]
NPT1139	Individual Protein	Arachidonate 15-lipoxygenase, type II	Homo sapiens	Potency	n.a.	17782.8	nM	PMID[474499]
NPT109	Individual Protein	Cytochrome P450 3A4	Homo sapiens	AC50	=	31622.78	nM	PMID[474498]
NPT208	Individual Protein	Cytochrome P450 1A2	Homo sapiens	AC50	=	31622.78	nM	PMID[474498]
NPT91	Cell Line	KB	Homo sapiens	IC50	=	0.45	ug.mL-1	PMID[474506]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	0.033	ug.mL-1	PMID[474506]
NPT111	Cell Line	K562	Homo sapiens	IC50	=	8.5	ug.mL-1	PMID[474506]
NPT111	Cell Line	K562	Homo sapiens	IC50	=	1.49	ug.mL-1	PMID[474506]
NPT395	Cell Line	SF-268	Homo sapiens	IC50	=	600.0	nM	PMID[474507]
NPT397	Cell Line	NCI-H460	Homo sapiens	IC50	=	380.0	nM	PMID[474507]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	5030.0	nM	PMID[474507]
NPT171	Cell Line	MRC5	Homo sapiens	IC50	=	880.0	nM	PMID[474507]
NPT397	Cell Line	NCI-H460	Homo sapiens	Ratio IC50	=	2.32	n.a.	PMID[474507]
NPT171	Cell Line	MRC5	Homo sapiens	Ratio IC50	=	0.17	n.a.	PMID[474507]
NPT395	Cell Line	SF-268	Homo sapiens	Ratio IC50	=	1.47	n.a.	PMID[474507]
NPT198	Individual Protein	Vitamin D receptor	Homo sapiens	Potency	n.a.	15848.9	nM	PMID[474498]
NPT199	Individual Protein	DNA polymerase kappa	Homo sapiens	Potency	n.a.	11917.3	nM	PMID[474499]
NPT199	Individual Protein	DNA polymerase kappa	Homo sapiens	Potency	n.a.	5011.9	nM	PMID[474498]
NPT444	Individual Protein	Ubiquitin carboxyl-terminal hydrolase 1	Homo sapiens	Potency	n.a.	44668.4	nM	PMID[474498]
NPT444	Individual Protein	Ubiquitin carboxyl-terminal hydrolase 1	Homo sapiens	Potency	n.a.	39810.7	nM	PMID[474499]
NPT445	Individual Protein	Peripheral myelin protein 22	Rattus norvegicus	Potency	n.a.	125.8	nM	PMID[474499]
NPT484	Individual Protein	Luciferin 4-monooxygenase	Photinus pyralis	Potency	n.a.	8087.5	nM	PMID[474499]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	400.0	nM	PMID[474513]
NPT858	Cell Line	LNCaP	Homo sapiens	IC50	=	100.0	nM	PMID[474513]
NPT139	Cell Line	HT-29	Homo sapiens	IC50	=	200.0	nM	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Inhibition	=	97.0	%	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Inhibition	=	36.0	%	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Inhibition	=	21.0	%	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Inhibition	=	95.0	%	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Inhibition	=	35.0	%	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Inhibition	=	17.0	%	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Inhibition	=	59.0	%	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Inhibition	=	26.0	%	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Inhibition	=	14.0	%	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Inhibition	=	46.0	%	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Inhibition	=	27.0	%	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Inhibition	=	16.0	%	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Ratio	=	0.85	n.a.	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Ratio	=	0.45	n.a.	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Ratio	=	0.49	n.a.	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Activity	=	121.0	%	PMID[474513]
NPT2103	Cell Line	MONO-MAC-6	Homo sapiens	Activity	=	142.0	%	PMID[474513]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	950.0	nM	PMID[474514]
NPT1506	Cell Line	SK-MES-1	Homo sapiens	IC50	=	170.0	nM	PMID[474514]
NPT90	Cell Line	DU-145	Homo sapiens	IC50	=	90.0	nM	PMID[474514]
NPT1594	Individual Protein	Multidrug resistance-associated protein 1	Homo sapiens	Km	=	1400.0	nM	PMID[474515]
NPT1594	Individual Protein	Multidrug resistance-associated protein 1	Homo sapiens	IC50	=	8000.0	nM	PMID[474529]
NPT1422	Individual Protein	ATP-binding cassette sub-family G member 2	Homo sapiens	Kact	=	2.5	uM	PMID[474531]
NPT1594	Individual Protein	Multidrug resistance-associated protein 1	Homo sapiens	Ki	=	70.0	nM	PMID[474532]
NPT1594	Individual Protein	Multidrug resistance-associated protein 1	Homo sapiens	Ki	=	950.0	nM	PMID[474533]
NPT612	Individual Protein	Canalicular multispecific organic anion transporter 1	Homo sapiens	Ki	=	49400.0	nM	PMID[474538]
NPT1044	Individual Protein	DNA topoisomerase II alpha	Homo sapiens	INH	=	0.5	mM	PMID[474539]
NPT65	Cell Line	HepG2	Homo sapiens	IC50	=	9120.0	nM	PMID[474540]
NPT10	Individual Protein	Geminin	Homo sapiens	Potency	n.a.	5309.1	nM	PMID[474499]
NPT1970	Cell Line	THP-1	Homo sapiens	IC50	=	26900.0	nM	PMID[474541]
NPT459	Individual Protein	Human immunodeficiency virus type 1 reverse transcriptase	Human immunodeficiency virus 1	IC50	=	139000.0	nM	PMID[474542]
NPT1581	Individual Protein	Carbonyl reductase [NADPH] 1	Homo sapiens	Km	=	51000.0	nM	PMID[474543]
NPT1581	Individual Protein	Carbonyl reductase [NADPH] 1	Homo sapiens	Km	=	108000.0	nM	PMID[474543]
NPT1581	Individual Protein	Carbonyl reductase [NADPH] 1	Homo sapiens	Kcat	=	1.94	/s	PMID[474543]
NPT1581	Individual Protein	Carbonyl reductase [NADPH] 1	Homo sapiens	Kcat	=	1.27	/s	PMID[474543]
NPT1581	Individual Protein	Carbonyl reductase [NADPH] 1	Homo sapiens	Vmax/Km	=	2140.0	U/mg	PMID[474543]
NPT1864	Cell Line	L5178Y	Mus musculus	Ratio IC50	>	10.0	n.a.	PMID[474546]
NPT1864	Cell Line	L5178Y	Mus musculus	IC50	=	7730.0	nM	PMID[474546]
NPT1864	Cell Line	L5178Y	Mus musculus	IC50	=	2320.0	nM	PMID[474547]
NPT1864	Cell Line	L5178Y	Mus musculus	IC50	=	730.0	nM	PMID[474546]
NPT1864	Cell Line	L5178Y	Mus musculus	IC50	=	300.0	nM	PMID[474547]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	33900.0	nM	PMID[474548]
NPT146	Cell Line	SK-OV-3	Homo sapiens	IC50	=	20600.0	nM	PMID[474548]
NPT50	Individual Protein	Tyrosyl-DNA phosphodiesterase 1	Homo sapiens	Potency	n.a.	26.6	nM	PMID[474549]
NPT50	Individual Protein	Tyrosyl-DNA phosphodiesterase 1	Homo sapiens	Potency	n.a.	37.6	nM	PMID[474498]
NPT50	Individual Protein	Tyrosyl-DNA phosphodiesterase 1	Homo sapiens	Potency	n.a.	23.7	nM	PMID[474498]
NPT50	Individual Protein	Tyrosyl-DNA phosphodiesterase 1	Homo sapiens	Potency	n.a.	21.1	nM	PMID[474549]
NPT49	Individual Protein	DNA-(apurinic or apyrimidinic site) lyase	Homo sapiens	Potency	n.a.	14125.4	nM	PMID[474498]
NPT49	Individual Protein	DNA-(apurinic or apyrimidinic site) lyase	Homo sapiens	Potency	n.a.	14125.4	nM	PMID[474549]
NPT137	Cell Line	L1210	Mus musculus	ED50	=	0.66	uM	PMID[474552]
NPT137	Cell Line	L1210	Mus musculus	ED50	=	0.33	uM	PMID[474552]
NPT168	Cell Line	P388	Mus musculus	Activity	=	2.9	mg kg-1	PMID[474553]
NPT168	Cell Line	P388	Mus musculus	T/C	=	169.0	%	PMID[474553]
NPT168	Cell Line	P388	Mus musculus	T/C	=	97.0	%	PMID[474555]
NPT168	Cell Line	P388	Mus musculus	T/C	=	122.0	%	PMID[474555]
NPT168	Cell Line	P388	Mus musculus	T/C	=	151.0	%	PMID[474555]
NPT168	Cell Line	P388	Mus musculus	T/C	=	123.0	%	PMID[474555]
NPT168	Cell Line	P388	Mus musculus	T/C	=	116.0	%	PMID[474555]
NPT319	Cell Line	B16	Mus musculus	T/C	=	96.0	%	PMID[474555]
NPT319	Cell Line	B16	Mus musculus	T/C	=	127.0	%	PMID[474555]
NPT319	Cell Line	B16	Mus musculus	T/C	=	122.0	%	PMID[474555]
NPT168	Cell Line	P388	Mus musculus	MED	=	0.52	mg kg-1	PMID[474556]
NPT168	Cell Line	P388	Mus musculus	Activity	=	98.0	mg kg-1	PMID[474556]
NPT137	Cell Line	L1210	Mus musculus	ED50	=	0.48	uM	PMID[474557]
NPT137	Cell Line	L1210	Mus musculus	ED50	=	0.23	uM	PMID[474557]
NPT168	Cell Line	P388	Mus musculus	T/C	=	83.0	%	PMID[474557]
NPT168	Cell Line	P388	Mus musculus	T/C	=	112.0	%	PMID[474557]
NPT168	Cell Line	P388	Mus musculus	T/C	=	162.0	%	PMID[474557]
NPT168	Cell Line	P388	Mus musculus	T/C	=	167.0	%	PMID[474557]
NPT168	Cell Line	P388	Mus musculus	T/C	=	152.0	%	PMID[474557]
NPT137	Cell Line	L1210	Mus musculus	ED50	=	0.66	uM	PMID[474558]
NPT137	Cell Line	L1210	Mus musculus	ED50	=	0.33	uM	PMID[474558]
NPT137	Cell Line	L1210	Mus musculus	Ratio ED50	=	2.0	n.a.	PMID[474558]
NPT168	Cell Line	P388	Mus musculus	T/C	=	160.0	%	PMID[474558]
NPT168	Cell Line	P388	Mus musculus	T/C	=	132.0	%	PMID[474558]
NPT137	Cell Line	L1210	Mus musculus	Inhibition	=	0.66	%	PMID[474559]
NPT137	Cell Line	L1210	Mus musculus	Inhibition	=	0.33	%	PMID[474559]
NPT168	Cell Line	P388	Mus musculus	T/C	=	148.0	%	PMID[474559]
NPT168	Cell Line	P388	Mus musculus	T/C	=	167.0	%	PMID[474559]
NPT168	Cell Line	P388	Mus musculus	T/C	=	153.0	%	PMID[474559]
NPT168	Cell Line	P388	Mus musculus	T/C	=	144.0	%	PMID[474559]
NPT168	Cell Line	P388	Mus musculus	T/C	=	127.0	%	PMID[474559]
NPT168	Cell Line	P388	Mus musculus	T/C	=	134.0	%	PMID[474559]
NPT168	Cell Line	P388	Mus musculus	T/C	=	131.0	%	PMID[474559]
NPT137	Cell Line	L1210	Mus musculus	Inhibition	=	37.0	%	PMID[474560]
NPT137	Cell Line	L1210	Mus musculus	Inhibition	=	68.8	%	PMID[474560]
NPT137	Cell Line	L1210	Mus musculus	Inhibition	=	83.0	%	PMID[474560]
NPT137	Cell Line	L1210	Mus musculus	Inhibition	=	47.6	%	PMID[474560]
NPT137	Cell Line	L1210	Mus musculus	Inhibition	=	69.8	%	PMID[474560]
NPT137	Cell Line	L1210	Mus musculus	Inhibition	=	74.8	%	PMID[474560]
NPT137	Cell Line	L1210	Mus musculus	Drug uptake	=	0.31	nmol	PMID[474560]
NPT137	Cell Line	L1210	Mus musculus	Ratio	=	119.0	n.a.	PMID[474560]
NPT137	Cell Line	L1210	Mus musculus	Ratio	=	155.0	n.a.	PMID[474560]
NPT165	Cell Line	HeLa	Homo sapiens	ID50	=	13.0	ng/ml	PMID[474561]
NPT1893	Cell Line	MEF	Mus musculus	ID50	=	9.0	ng/ml	PMID[474561]
NPT1893	Cell Line	MEF	Mus musculus	ID50	=	5.5	ng/ml	PMID[474561]
NPT2870	Cell Line	Sarcoma-180	Mus musculus	T/C	=	192.0	%	PMID[474561]
NPT137	Cell Line	L1210	Mus musculus	ED50	=	0.3	uM	PMID[474562]
NPT168	Cell Line	P388	Mus musculus	T/C	=	96.0	n.a.	PMID[474562]
NPT168	Cell Line	P388	Mus musculus	T/C	=	150.0	n.a.	PMID[474562]
NPT168	Cell Line	P388	Mus musculus	T/C	=	157.0	n.a.	PMID[474562]
NPT168	Cell Line	P388	Mus musculus	T/C	=	142.0	n.a.	PMID[474562]
NPT168	Cell Line	P388	Mus musculus	T/C	=	130.0	n.a.	PMID[474562]
NPT168	Cell Line	P388	Mus musculus	T/C	=	112.0	n.a.	PMID[474562]
NPT81	Cell Line	A549	Homo sapiens	IC50	=	80.0	nM	PMID[474565]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	650.0	nM	PMID[474565]
NPT82	Cell Line	MDA-MB-231	Homo sapiens	IC50	=	91.0	nM	PMID[474565]
NPT171	Cell Line	MRC5	Homo sapiens	IC50	=	78.0	nM	PMID[474565]
NPT71	Cell Line	HEK293	Homo sapiens	IC50	=	12550.0	nM	PMID[474572]
NPT71	Cell Line	HEK293	Homo sapiens	IC50	=	12550.0	nM	PMID[474575]
NPT2454	Cell Line	RD	Homo sapiens	IC50	=	2450.0	nM	PMID[474577]
NPT81	Cell Line	A549	Homo sapiens	IC50	=	510.0	nM	PMID[474577]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	1440.0	nM	PMID[474577]
NPT71	Cell Line	HEK293	Homo sapiens	IC50	=	11170.0	nM	PMID[474577]
NPT1535	Cell Line	U-87 MG	Homo sapiens	IC50	=	27.9	nM	PMID[474580]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	286.0	nM	PMID[474580]
NPT82	Cell Line	MDA-MB-231	Homo sapiens	IC50	=	52.9	nM	PMID[474580]
NPT3722	Cell Line	4T1	Mus musculus	IC50	=	40.8	nM	PMID[474580]
NPT393	Cell Line	HCT-116	Homo sapiens	IC50	=	127.1	nM	PMID[474580]
NPT139	Cell Line	HT-29	Homo sapiens	IC50	=	202.9	nM	PMID[474580]
NPT1183	Cell Line	WiDr	Homo sapiens	IC50	=	240.1	nM	PMID[474580]
NPT65	Cell Line	HepG2	Homo sapiens	IC50	=	21.3	nM	PMID[474580]
NPT81	Cell Line	A549	Homo sapiens	IC50	=	68.2	nM	PMID[474580]
NPT1820	Cell Line	NCI-H1650	Homo sapiens	IC50	=	47.5	nM	PMID[474580]
NPT2341	Cell Line	NCI-H1975	Homo sapiens	IC50	=	13.3	nM	PMID[474580]
NPT1383	Cell Line	A2058	Homo sapiens	IC50	=	33.3	nM	PMID[474580]
NPT319	Cell Line	B16	Mus musculus	IC50	=	8.9	nM	PMID[474580]
NPT377	Cell Line	OVCAR-3	Homo sapiens	IC50	=	472.9	nM	PMID[474580]
NPT461	Cell Line	PANC-1	Homo sapiens	IC50	=	466.7	nM	PMID[474580]
NPT90	Cell Line	DU-145	Homo sapiens	IC50	=	24.5	nM	PMID[474580]
NPT306	Cell Line	PC-3	Homo sapiens	IC50	=	26.0	nM	PMID[474580]
NPT171	Cell Line	MRC5	Homo sapiens	IC50	=	254.7	nM	PMID[474580]
NPT139	Cell Line	HT-29	Homo sapiens	Inhibition	=	84.0	%	PMID[474580]
NPT139	Cell Line	HT-29	Homo sapiens	Activity	=	94.0	%	PMID[474580]
NPT139	Cell Line	HT-29	Homo sapiens	Inhibition	=	30.0	%	PMID[474580]
NPT81	Cell Line	A549	Homo sapiens	IC50	=	150.0	nM	PMID[474581]
NPT71	Cell Line	HEK293	Homo sapiens	IC50	=	11170.0	nM	PMID[474582]
NPT83	Cell Line	MCF7	Homo sapiens	IC50	=	560.0	nM	PMID[474582]
NPT393	Cell Line	HCT-116	Homo sapiens	IC50	=	210.0	nM	PMID[474582]
NPT2454	Cell Line	RD	Homo sapiens	IC50	=	2450.0	nM	PMID[474582]
NPT81	Cell Line	A549	Homo sapiens	IC50	=	530.0	nM	PMID[474582]
NPT1970	Cell Line	THP-1	Homo sapiens	Ratio IC50	=	1.0	n.a.	PMID[474584]
NPT3722	Cell Line	4T1	Mus musculus	IC50	=	300.0	nM	PMID[474585]
NPT2846	Cell Line	BHK-21	Cricetulus griseus	IC50	=	90.0	nM	PMID[474585]
NPT2	Others	Unspecified		Potency	n.a.	5955.7	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	33488.9	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	530.8	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	749.8	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	7562.4	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	477.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	1059.1	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	1059	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	1496	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	12589.3	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	2.4	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	17550.7	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	149.6	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	14960.1	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	2660.3	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	13332.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	595.6	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	4771.6	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	9439.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	1068.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	11220.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	1899.6	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	37.6	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	8485.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	10590.9	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	375.8	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	23.7	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	237.1	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	3348.9	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	21131.7	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	10.6	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	11.9	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	1188.2	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	3757.8	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	943.9	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	3790.2	nM	PubChem BioAssay data set
NPT74	Individual Protein	Proto-oncogene c-JUN	Homo sapiens	Potency	n.a.	10.7	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	952.1	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	26832.5	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	1678.5	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	33.5	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	3010.7	nM	PubChem BioAssay data set
NPT2	Others	Unspecified		Potency	n.a.	1693	nM	PubChem BioAssay data set
NPT32	Organism	Mus musculus	Mus musculus	O2 consumption	=	109.0	%	PMID[474427]
NPT32	Organism	Mus musculus	Mus musculus	O2 consumption	=	82.0	%	PMID[474427]
NPT317	Uncleic Acid	Nucleic Acid		Delta Tm	=	11.2	degrees C	PMID[474427]
NPT2	Others	Unspecified		RF	=	295.7	n.a.	PMID[474429]
NPT32	Organism	Mus musculus	Mus musculus	T/C	=	105.0	%	PMID[474430]
NPT317	Uncleic Acid	Nucleic Acid		Log Kd	=	6.49	n.a.	PMID[474431]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	<	20.0	nM	PMID[474434]
NPT2	Others	Unspecified		Oxidation	=	33.0	uM min-1	PMID[474435]
NPT2	Others	Unspecified		Log CR	=	1.46	n.a.	PMID[474436]
NPT35	Others	n.a.		LogD	=	0.66	n.a.	PMID[474436]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	EC50	=	58.0	nM	PMID[474437]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	EC50	=	220.0	nM	PMID[474437]
NPT35	Others	n.a.		LogD	=	0.66	n.a.	PMID[474438]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	ID50	=	309.0	ng ml-1	PMID[474439]
NPT32	Organism	Mus musculus	Mus musculus	Increase in life-span	=	42.0	%	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Survivors	=	0.0	n.a.	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Weight change	=	-1.1	%	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Increase in life-span	=	66.0	%	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Weight change	=	-3.2	%	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Increase in life-span	=	123.0	%	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Survivors	=	6.0	n.a.	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Weight change	=	-8.4	%	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Increase in life-span	=	65.0	%	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Diameter	=	0.3	mM	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Diameter	=	4.1	mM	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Weight change	=	-4.3	%	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Increase in life-span	=	67.0	%	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Survivors	=	3.0	n.a.	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Diameter	=	0.4	mM	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Diameter	=	2.9	mM	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Weight change	=	-5.9	%	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Increase in life-span	=	83.0	%	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Diameter	=	0.0	mM	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Diameter	=	2.0	mM	PMID[474440]
NPT32	Organism	Mus musculus	Mus musculus	Weight change	=	-6.3	%	PMID[474440]
NPT2	Others	Unspecified		IC50	=	38.18	nM	PMID[474441]
NPT32	Organism	Mus musculus	Mus musculus	T/C	=	44.8	%	PMID[474444]
NPT32	Organism	Mus musculus	Mus musculus	T/C	=	117.0	%	PMID[474444]
NPT32	Organism	Mus musculus	Mus musculus	Mean tumor volume	=	1154.0	n.a.	PMID[474444]
NPT32	Organism	Mus musculus	Mus musculus	Tumor growth	=	1226.0	%	PMID[474444]
NPT32	Organism	Mus musculus	Mus musculus	T/C	=	92.0	%	PMID[474444]
NPT32	Organism	Mus musculus	Mus musculus	T/C	=	54.0	%	PMID[474444]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	11.1	n.a.	PMID[474445]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	11.9	n.a.	PMID[474445]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	5.3	n.a.	PMID[474445]
NPT19	Organism	Escherichia coli	Escherichia coli	Activity	=	3.1	n.a.	PMID[474445]
NPT32	Organism	Mus musculus	Mus musculus	ILS	=	91.0	%	PMID[474446]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Activity	=	2.76	n.a.	PMID[474447]
NPT317	Uncleic Acid	Nucleic Acid		Kd	=	1.28	n.a.	PMID[474447]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	=	20.0	ug.mL-1	PMID[474447]
NPT16	Organism	Staphylococcus aureus	Staphylococcus aureus	MIC	<	5.0	ug.mL-1	PMID[474447]
NPT17	Organism	Staphylococcus epidermidis	Staphylococcus epidermidis	MIC	<	5.0	ug.mL-1	PMID[474447]
NPT1228	Organism	Streptococcus pyogenes	Streptococcus pyogenes	MIC	<	5.0	ug.mL-1	PMID[474447]
NPT314	Organism	Bacillus cereus	Bacillus cereus	MIC	<	5.0	ug.mL-1	PMID[474447]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	MIC	<	5.0	ug.mL-1	PMID[474447]
NPT4068	Organism	Corynebacterium diphtheriae	Corynebacterium diphtheriae	MIC	<	5.0	ug.mL-1	PMID[474447]
NPT317	Uncleic Acid	Nucleic Acid		Ka	=	0.00000031	M-1	PMID[474449]
NPT317	Uncleic Acid	Nucleic Acid		Maximal binding	=	0.16	n.a.	PMID[474449]
NPT32	Organism	Mus musculus	Mus musculus	Growth delay	=	0.0	day	PMID[474451]
NPT32	Organism	Mus musculus	Mus musculus	Cures	=	0.0	n.a.	PMID[474451]
NPT25183	SINGLE PROTEIN	Dihydrofolate reductase	Mus musculus	Log 1/C	=	7.17	n.a.	PMID[474455]
NPT25183	SINGLE PROTEIN	Dihydrofolate reductase	Mus musculus	Log 1/C	=	7.1	n.a.	PMID[474455]
NPT35	Others	n.a.		LogP	=	0.66	n.a.	PMID[474455]
NPT27	Others	Unspecified		Change in Tm	=	10.5	n.a.	PMID[474457]
NPT35	Others	n.a.		LogD	=	0.66	n.a.	PMID[474457]
NPT35	Others	n.a.		P	=	4.5	n.a.	PMID[474459]
NPT317	Uncleic Acid	Nucleic Acid		K	=	0.0000015	M	PMID[474459]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	=	0.08	n.a.	PMID[474459]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	=	0.022	n.a.	PMID[474459]
NPT35	Others	n.a.		Log Kmemb	=	1.4	n.a.	PMID[474460]
NPT32	Organism	Mus musculus	Mus musculus	Activity	=	50.0	%	PMID[474466]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	=	20.0	nM	PMID[474469]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	>	400.0	nM	PMID[474469]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	>	1000.0	nM	PMID[474469]
NPT2	Others	Unspecified		IC50	=	28.0	ug.mL-1	PMID[474471]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	=	18620.87	nM	PMID[474472]
NPT1881	Uncleic Acid	Calf thymus DNA	Bos taurus	Activity	=	100.0	%	PMID[474473]
NPT1514	Uncleic Acid	DNA	Bos taurus	K	=	2.3	/M	PMID[474478]
NPT27	Others	Unspecified		IC50	=	44.0	nM	PMID[474479]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	MIC	=	0.6	ug.mL-1	PMID[474480]
NPT79	Organism	Bacillus subtilis	Bacillus subtilis	LD99	=	0.1	ug ml-1	PMID[474480]
NPT317	Uncleic Acid	Nucleic Acid		IC50	=	30.0	ug.mL-1	PMID[474483]
NPT1881	Uncleic Acid	Calf thymus DNA	Bos taurus	IC50	=	2.0	ug.mL-1	PMID[474483]
NPT27	Others	Unspecified		permeability	=	0.3	10'-6 cm/s	PMID[474486]
NPT605	Organism	Homo sapiens	Homo sapiens	F	=	0.0	%	PMID[474486]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	GI50	=	44.0	nM	PMID[474487]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	>	100.0	ug.mL-1	PMID[474489]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	=	16200.0	nM	PMID[474491]
NPT35	Others	n.a.		LogP	=	0.1	n.a.	PMID[474492]
NPT2	Others	Unspecified		K	=	4.6	10'4/M	PMID[474495]
NPT2	Others	Unspecified		K	=	6.4	10'4/M	PMID[474495]
NPT312	Organism	Saccharomyces cerevisiae	Saccharomyces cerevisiae	IZ	=	5.0	mm	PMID[474496]
NPT312	Organism	Saccharomyces cerevisiae	Saccharomyces cerevisiae	IZ	=	0.0	mm	PMID[474496]
NPT1881	Uncleic Acid	Calf thymus DNA	Bos taurus	Delta Tm	=	21.9	degrees C	PMID[474497]
NPT197	Protein-Protein Interaction	Menin/Histone-lysine N-methyltransferase MLL	Homo sapiens	Potency	=	14125.4	nM	PMID[474498]
NPT197	Protein-Protein Interaction	Menin/Histone-lysine N-methyltransferase MLL	Homo sapiens	Potency	=	2818.4	nM	PMID[474499]
NPT2	Others	Unspecified		Potency	=	631.0	nM	PMID[474499]
NPT2	Others	Unspecified		Potency	=	1000.0	nM	PMID[474498]
NPT2	Others	Unspecified		Potency	=	398.1	nM	PMID[474499]
NPT94	Individual Protein	Aldehyde dehydrogenase 1A1	Homo sapiens	Potency	=	39810.7	nM	PMID[474498]
NPT197	Protein-Protein Interaction	Menin/Histone-lysine N-methyltransferase MLL	Homo sapiens	Potency	=	12589.3	nM	PMID[474498]
NPT197	Protein-Protein Interaction	Menin/Histone-lysine N-methyltransferase MLL	Homo sapiens	Potency	=	15848.9	nM	PMID[474499]
NPT27	Others	Unspecified		IC50	=	10500.0	nM	PMID[474500]
NPT27	Others	Unspecified		IC50	=	1800.0	nM	PMID[474500]
NPT841	Organism	Leishmania major	Leishmania major	EC50	=	220.0	nM	PMID[474502]
NPT841	Organism	Leishmania major	Leishmania major	EC50	=	380.0	nM	PMID[474502]
NPT841	Organism	Leishmania major	Leishmania major	Ratio EC50	=	1.7	n.a.	PMID[474502]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	Composite Activity - Active	=	0.0	n.a.	PMID[474504]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	Composite Activity - Marginal	=	0.0	n.a.	PMID[474504]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	Alkaline Phosphatase Increase - Index Value	=	0.0	n.a.	PMID[474504]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	Alkaline Phosphatase Increase - Number of Reports	<	4.0	n.a.	PMID[474504]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	SGOT Increase - Index Value	=	0.0	n.a.	PMID[474504]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	SGOT Increase - Number of Reports	<	4.0	n.a.	PMID[474504]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	SGPT Increase - Index Value	=	0.0	n.a.	PMID[474504]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	SGPT Increase - Number of Reports	<	4.0	n.a.	PMID[474504]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	LDH Increase - Index Value	=	0.0	n.a.	PMID[474504]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	LDH Increase - Number of Reports	<	4.0	n.a.	PMID[474504]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	GGT Increase - Index Value	=	0.0	n.a.	PMID[474504]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	GGT Increase - Number of Reports	<	4.0	n.a.	PMID[474504]
NPT533	Protein-Protein Interaction	Runt-related transcription factor 1/Core-binding factor subunit beta	Homo sapiens	Potency	n.a.	251.2	nM	PMID[474498]
NPT533	Protein-Protein Interaction	Runt-related transcription factor 1/Core-binding factor subunit beta	Homo sapiens	Potency	n.a.	3981.1	nM	PMID[474499]
NPT25185	NUCLEIC-ACID	Poly(dA-dT)oligonucleotide	n.a.	Delta Tm	=	21.9	degrees C	PMID[474505]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	=	7.9	ug.mL-1	PMID[474506]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	=	11.6	ug.mL-1	PMID[474506]
NPT6	Organism	Plasmodium falciparum	Plasmodium falciparum	Potency	n.a.	674.6	nM	PMID[474499]
NPT6	Organism	Plasmodium falciparum	Plasmodium falciparum	Potency	n.a.	756.9	nM	PMID[474499]
NPT901	Individual Protein	UDP-glucuronosyltransferase 1-1	Homo sapiens	Activity	=	0.0	pm/min/mg	PMID[474508]
NPT702	Individual Protein	UDP-glucuronosyltransferase 1-6	Homo sapiens	Activity	=	0.0	pm/min/mg	PMID[474508]
NPT703	Individual Protein	UDP-glucuronosyltransferase 1-9	Homo sapiens	Activity	=	0.0	pm/min/mg	PMID[474508]
NPT668	Individual Protein	P-glycoprotein 1	Homo sapiens	Papp	=	5.47	nm/s	PMID[474509]
NPT668	Individual Protein	P-glycoprotein 1	Homo sapiens	Papp	=	77.7	nm/s	PMID[474509]
NPT668	Individual Protein	P-glycoprotein 1	Homo sapiens	Ratio_Papp	=	14.2	n.a.	PMID[474509]
NPT668	Individual Protein	P-glycoprotein 1	Homo sapiens	Ratio_ATPase activity	=	1.69	n.a.	PMID[474509]
NPT668	Individual Protein	P-glycoprotein 1	Homo sapiens	% maximum response	=	-0.69	%	PMID[474509]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_bilirubinemia	=	0.0	n.a.	PMID[474511]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_cholecystitis	=	0.0	n.a.	PMID[474511]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_cholelithiasis	=	0.0	n.a.	PMID[474511]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_cirrhosis	=	0.0	n.a.	PMID[474511]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_elevated liver function tests	=	0.0	n.a.	PMID[474511]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_hepatic failure	=	0.0	n.a.	PMID[474511]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_hepatic necrosis	=	0.0	n.a.	PMID[474511]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_hepatitis	=	0.0	n.a.	PMID[474511]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_hepatomegaly	=	1.0	n.a.	PMID[474511]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_jaundice	=	0.0	n.a.	PMID[474511]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_liver disease	=	0.0	n.a.	PMID[474511]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_liver fatty	=	0.0	n.a.	PMID[474511]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_liver function tests abnormal	=	0.0	n.a.	PMID[474511]
NPT20596	PHENOTYPE	Hepatotoxicity	n.a.	HepSE_Combined Scores	=	1.0	n.a.	PMID[474511]
NPT317	Uncleic Acid	Nucleic Acid		Inhibition	=	19.0	%	PMID[474512]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	GI	=	24.4	%	PMID[474513]
NPT668	Individual Protein	P-glycoprotein 1	Homo sapiens	Km	=	1740.0	nM	PMID[474516]
NPT668	Individual Protein	P-glycoprotein 1	Homo sapiens	Ki	=	111000.0	nM	PMID[474534]
NPT668	Individual Protein	P-glycoprotein 1	Homo sapiens	Ki	=	2500.0	nM	PMID[474537]
NPT474	Organism	Plasmodium berghei	Plasmodium berghei	IC50	=	2990.0	nM	PMID[474540]
NPT6	Organism	Plasmodium falciparum	Plasmodium falciparum	IC50	=	340.0	nM	PMID[474540]
NPT6	Organism	Plasmodium falciparum	Plasmodium falciparum	IC50	=	155.0	nM	PMID[474540]
NPT2	Others	Unspecified		Potency	n.a.	5645.4	nM	PMID[474499]
NPT2	Others	Unspecified		Potency	n.a.	68530.8	nM	PMID[474499]
NPT533	Protein-Protein Interaction	Runt-related transcription factor 1/Core-binding factor subunit beta	Homo sapiens	Potency	n.a.	15848.9	nM	PMID[474498]
NPT2	Others	Unspecified		Potency	n.a.	11264.1	nM	PMID[474499]
NPT3697	Organism	Leishmania tropica	Leishmania tropica	IC50	=	2800.0	nM	PMID[474541]
NPT3697	Organism	Leishmania tropica	Leishmania tropica	Ratio IC50	=	64.0	n.a.	PMID[474541]
NPT3697	Organism	Leishmania tropica	Leishmania tropica	IC50	=	179800.0	nM	PMID[474541]
NPT683	Individual Protein	Aldehyde reductase	Homo sapiens	Activity	=	120.0	nmol/min	PMID[474543]
NPT683	Individual Protein	Aldehyde reductase	Homo sapiens	Vmax/Km	=	312.0	U/mg	PMID[474543]
NPT317	Uncleic Acid	Nucleic Acid		K	=	7.09	10'5/M	PMID[474544]
NPT27	Others	Unspecified		Activity	=	0.12	U	PMID[474545]
NPT27	Others	Unspecified		Drug uptake	=	83.19	%	PMID[474548]
NPT2	Others	Unspecified		IC50	=	140.0	nM	PMID[474548]
NPT2	Others	Unspecified		IC50	=	840.0	nM	PMID[474548]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	Activity	=	80.0	%	PMID[474548]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	=	25500.0	nM	PMID[474548]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	=	1900.0	nM	PMID[474548]
NPT2	Others	Unspecified		Activity	=	2.2	uM	PMID[474550]
NPT2	Others	Unspecified		IC50	=	1100.0	nM	PMID[474550]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (moderate)	=	3.0	n.a.	PMID[474551]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (moderate)	=	68.0	%	PMID[474551]
NPT2	Others	Unspecified		Hepatotoxicity (acute)	=	2.0	n.a.	PMID[474551]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (acute)	=	0.0	%	PMID[474551]
NPT2	Others	Unspecified		Hepatotoxicity (cytolytic)	=	2.0	n.a.	PMID[474551]
NPT2	Others	Unspecified		Hepatotoxicity (choleostasis)	=	0.0	n.a.	PMID[474551]
NPT2	Others	Unspecified		Hepatotoxicity (severe hepatitis)	=	0.0	n.a.	PMID[474551]
NPT2	Others	Unspecified		Hepatotoxicity (chronic liver disease)	=	0.0	n.a.	PMID[474551]
NPT2	Others	Unspecified		Hepatotoxicity (cirrhosis)	=	0.0	n.a.	PMID[474551]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (granulomatous hepatitis)	=	0.0	n.a.	PMID[474551]
NPT2	Others	Unspecified		Hepatotoxicity (association with vascular disease)	=	2.0	n.a.	PMID[474551]
NPT2	Others	Unspecified		Hepatotoxicity (steatosis)	=	0.0	n.a.	PMID[474551]
NPT2	Others	Unspecified		Hepatotoxicity (malignant tumour)	=	0.0	n.a.	PMID[474551]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	Hepatotoxicity (benign tumour)	=	0.0	n.a.	PMID[474551]
NPT2	Others	Unspecified		Potency	n.a.	35481.3	nM	PMID[474498]
NPT2	Others	Unspecified		Potency	n.a.	891.3	nM	PMID[474549]
NPT2	Others	Unspecified		Potency	n.a.	3162.3	nM	PMID[474498]
NPT2	Others	Unspecified		Potency	n.a.	6309.6	nM	PMID[474549]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	D50	=	1.31	10'-5M	PMID[474554]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	D50	=	1.11	10'-5M	PMID[474554]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	D50	=	0.74	10'-5M	PMID[474554]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	M50	=	20.0	%	PMID[474554]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	M50	=	4.5	%	PMID[474554]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	M50	=	0.0	%	PMID[474554]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	log(M50)	=	0.0	n.a.	PMID[474554]
NPT32	Organism	Mus musculus	Mus musculus	MTD	=	5.2	mg kg-1	PMID[474556]
NPT27	Others	Unspecified		TI	=	10.0	n.a.	PMID[474556]
NPT1881	Uncleic Acid	Calf thymus DNA	Bos taurus	Delta Tm	=	11.0	degrees C	PMID[474557]
NPT35	Others	n.a.		LogP	=	0.82	n.a.	PMID[474557]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCCD	=	14.0	mg kg-1	PMID[474557]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	Ratio	=	1.3	n.a.	PMID[474557]
NPT1881	Uncleic Acid	Calf thymus DNA	Bos taurus	Delta Tm	=	11.2	degrees C	PMID[474558]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MTC	=	14.0	mg kg-1	PMID[474558]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	Activity	=	100.0	/nmol	PMID[474558]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	Activity	=	5.0	ug	PMID[474558]
NPT1881	Uncleic Acid	Calf thymus DNA	Bos taurus	Delta Tm	=	11.2	degrees C	PMID[474559]
NPT1881	Uncleic Acid	Calf thymus DNA	Bos taurus	Delta Tm	=	16.8	degrees C	PMID[474562]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	IC50	=	96.0	nM	PMID[474565]
NPT566	Organism	Salmonella typhimurium	Salmonella enterica subsp. enterica serovar Typhimurium	Activity	=	902.0	n.a.	PMID[474566]
NPT27	Others	Unspecified		DC50	=	0.001	mM	PMID[474567]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	GI50	=	38000.0	nM	PMID[474568]
NPT20529	NON-MOLECULAR	NON-PROTEIN TARGET	n.a.	GI50	=	100.0	nM	PMID[474568]
NPT27	Others	Unspecified		T1/2	=	0.08833	hr	PMID[474569]
NPT27	Others	Unspecified		T1/2	=	24.2	hr	PMID[474569]
NPT27	Others	Unspecified		Vd	=	51.0	L.kg-1	PMID[474569]
NPT27	Others	Unspecified		Clp	=	2031.0	ml.min-1	PMID[474569]
NPT27	Others	Unspecified		Clp	=	59.0	ml.min-1	PMID[474569]
NPT27	Others	Unspecified		AUC	=	86.0	ug.ml-1	PMID[474569]
NPT27	Others	Unspecified		Ratio	=	-16.0	n.a.	PMID[474570]
NPT27	Others	Unspecified		Ratio	=	0.4	n.a.	PMID[474570]
NPT27	Others	Unspecified		Papp	=	0.4	ucm/s	PMID[474570]
NPT27	Others	Unspecified		Papp	=	0.9	ucm/s	PMID[474570]
NPT27	Others	Unspecified		Ratio	=	2.5	n.a.	PMID[474570]
NPT27	Others	Unspecified		Ratio	=	69.0	n.a.	PMID[474570]
NPT27	Others	Unspecified		Ratio	=	19.0	n.a.	PMID[474570]
NPT27	Others	Unspecified		Ratio	=	165.0	n.a.	PMID[474570]
NPT27	Others	Unspecified		Ratio	=	33.0	n.a.	PMID[474570]
NPT27	Others	Unspecified		Ratio	=	27.0	n.a.	PMID[474570]
NPT27	Others	Unspecified		Ratio	=	9.0	n.a.	PMID[474570]
NPT27	Others	Unspecified		Papp	=	2.1	ucm/s	PMID[474570]
NPT605	Organism	Homo sapiens	Homo sapiens	Fabs	=	10.0	%	PMID[474570]
NPT27	Others	Unspecified		Ratio	=	1.2	n.a.	PMID[474570]
NPT27	Others	Unspecified		Papp	=	3.2	ucm/s	PMID[474570]
NPT27	Others	Unspecified		Papp	=	2.7	ucm/s	PMID[474570]
NPT27	Others	Unspecified		Ratio	=	3.3	n.a.	PMID[474570]
NPT27	Others	Unspecified		Papp	=	1.6	ucm/s	PMID[474570]
NPT27	Others	Unspecified		Papp	=	0.5	ucm/s	PMID[474570]
NPT23140	TISSUE	Intestine	Mus musculus	Ratio AUC	=	3.0	n.a.	PMID[474570]
NPT27	Others	Unspecified		Ratio	=	83.0	n.a.	PMID[474570]
NPT27	Others	Unspecified		Ratio	=	86.0	n.a.	PMID[474570]
NPT2	Others	Unspecified		IC50	=	369.1	nM	PMID[474571]
NPT2	Others	Unspecified		Ac50	n.a.	2.432	uM	PMID[474571]
NPT2	Others	Unspecified		AC50	n.a.	7079.5	nM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	46.45	nM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	6.1	nM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	9604.6	nM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	648.46	nM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	188.04	nM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	55.38	nM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	8.05	nM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	50.86	nM	PMID[474571]
NPT2	Others	Unspecified		Ac50	n.a.	5.012	uM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	1465.78	nM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	337.6	nM	PMID[474571]
NPT2	Others	Unspecified		Ac50	n.a.	7.079	uM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	118.15	nM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	9247.6	nM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	10.16	nM	PMID[474571]
NPT2	Others	Unspecified		IC50	=	373.8	nM	PMID[474571]
NPT2	Others	Unspecified		Ac50	n.a.	2.728	uM	PMID[474571]
NPT2	Others	Unspecified		AC50	n.a.	5011.9	nM	PMID[474571]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	34.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	40300.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	345.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	69.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	143.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	46000000.0	nM	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	102.67	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	850.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	292.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	2.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1680.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	114.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	13.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	112.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	7.07	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	144.67	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	2.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	65700.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	7.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.0733	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.0867	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	8.4	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.35	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.63	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.73	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	6550000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	42.83	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	136000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	11330.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	74.77	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	20.77	pg	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	317000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	65.53	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	3.0	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	20.2	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1394330.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	31.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	447.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	61.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	156.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	43000000.0	nM	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	103.33	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	836.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	174.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	4.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1730.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	87.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	17.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	102.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.47	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	143.67	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	3.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	66300.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	10.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.14	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.0433	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	7.57	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.16	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	1.47	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.47	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	6680000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	44.33	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	144300.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	9330.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	81.23	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	21.67	pg	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	326000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	66.43	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.73	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	14.7	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1341670.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	31.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	39300.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	394.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	65.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	40670000.0	nM	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	104.33	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	663.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	346.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	3.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1766.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	109.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	14.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	111.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.53	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	146.0	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	64700.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	9.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.0533	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.21	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	8.22	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.2	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.53	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	2.1	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7000000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	44.0	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	145300.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	10440.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	78.07	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	330000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	62.87	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.87	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	16.8	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1104330.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	32.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	38300.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	334.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	69.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	160.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	40000000.0	nM	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	105.67	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	703.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	144.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	3.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1776.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	97.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	16.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	108.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.77	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	143.33	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	3.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	63700.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	1.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.0933	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.08	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	6.89	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.17	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	1.0	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.83	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7030000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	43.4	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	148300.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	8940.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	77.93	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	21.1	pg	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	341700.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	61.77	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.33	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	18.0	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1097330.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	37.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	397.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	67.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	136.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	39330000.0	nM	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	104.67	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	840.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	230.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	2.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1790.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	60.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	9.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	115.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.13	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	2.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	10.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.03	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.06	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	7.16	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.26	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.33	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.67	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	6430000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	42.57	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	135000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	9230.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	77.03	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	21.03	pg	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	317300.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	66.3	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	2.83	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	18.5	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1328670.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	39000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	354.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	68.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	166.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	36000000.0	nM	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	104.0	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	676.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	219.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1750.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	174.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	11.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	122.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	142.67	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	64300.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	11.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.11	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	7.08	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.14	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	1.17	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	2.47	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	6670000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	42.37	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	139700.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	8700.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	80.87	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	20.97	pg	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	63.57	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.7	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	13.37	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1161670.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	27.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	361.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	66.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	146.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	35000000.0	nM	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	106.67	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	686.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	274.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1923.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	118.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	9.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	118.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.67	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	63300.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	13.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.075	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.04	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	7.99	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.9	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.5	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	6820000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	42.9	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	137500.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	9390.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	84.25	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	20.2	pg	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	321500.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	62.9	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	1.5	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	12.5	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1293500.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	31.8	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	38800.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	326.6	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	64.8	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	166.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	42400000.0	nM	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	106.0	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	664.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	203.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1676.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	70.4	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	12.4	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	94.2	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.3	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	144.4	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	4.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	63600.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	0.4	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.12	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.074	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	8.83	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.25	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	1.1	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.66	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	7410000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	45.06	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	151000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	11000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	80.4	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	20.36	pg	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	334600.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	60.78	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	2.0	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	15.02	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1090800.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	55.5	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	42200.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	406.83	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	101.5	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	135.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	30330000.0	nM	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	102.17	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	636.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	732.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1570.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	442.5	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	10.83	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	126.8	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.67	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	144.0	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	1.5	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	60200.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	15.5	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASO	=	0.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	21.67	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	10193.67	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	165.83	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	702.17	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BASOLE	=	0.0	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.17	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	5390000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	34.62	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	138000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	11080.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	91.83	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	25.68	pg	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	399000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	64.37	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	6.5	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBCNUC	=	0.0	/100WBC	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1202830.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	51.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	41200.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	392.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	81.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	161.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	30670000.0	nM	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	100.5	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	648.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	242.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1868.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	188.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	116.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.51	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	142.55	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	2.2	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	60800.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	18.5	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	17.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	11849.17	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	69.83	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	730.67	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	5930000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	37.42	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	144000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	12670.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	93.17	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	24.32	pg	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	385000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	63.08	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	0.5	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	6.17	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1170500.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	49.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	43000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	483.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	96.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	130.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	32000000.0	nM	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	102.0	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	680.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	467.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	1.8	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1400.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	538.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	124.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.25	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	144.73	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	60300.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	14.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	88.67	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	11065.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	285.33	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	861.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	5460000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	37.0	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	146000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	12300.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	90.0	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	26.73	pg	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	394300.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	67.8	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	2.33	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	7.0	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1147330.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	40.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	41300.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	363.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	68.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	606.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	158.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	1.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1573.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	106.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.11	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	143.17	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	2.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	URATE	=	16.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	81.67	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	10522.67	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	79.33	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	716.33	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	5660000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	35.43	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	11400.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	92.33	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	24.7	pg	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	62.63	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	0.67	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	6.33	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1302000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	38.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALB	=	41000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALP	=	446.0	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	74.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CO2	=	32670000.0	nM	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	101.67	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	953.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	541.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	1.4	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1473.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	130.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LIPASE	=	10.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	118.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	6.29	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	142.93	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	1.7	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	59700.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOS	=	0.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	3258.33	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONO	=	0.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	475.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	EOSLE	=	0.0	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	5310000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	33.93	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	139000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	3730.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	87.0	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	26.17	pg	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	410000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	63.9	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MONOLE	=	0.0	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	13.0	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1193330.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	ALT	=	39.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	AST	=	63.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BUN	=	150.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHLORIDE	=	100.67	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CHOL	=	870.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CK	=	449.67	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	CREAT	=	1.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	GLUC	=	1743.3	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LDH	=	115.33	U.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PHOS	=	108.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	POTASSIUM	=	5.18	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	SODIUM	=	141.57	mEq.L-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	BILI	=	1.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PROT	=	61000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYM	=	1620.67	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTSG	=	79.33	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	RBC	=	5540000.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HCT	=	33.07	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	HGB	=	131700.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	WBC	=	1700.0	cells.uL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	LYMLE	=	95.67	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCH	=	23.77	pg	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCHC	=	398000.0	ug.mL-1	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	MCV	=	59.7	fL	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	NEUTLE	=	4.33	%	PMID[474573]
NPT29	Organism	Rattus norvegicus	Rattus norvegicus	PLAT	=	1023670.0	cells.uL-1	PMID[474573]
NPT20985	CELL-LINE	MCF7-ADR	Homo sapiens	IC50	=	7120.0	nM	PMID[474574]
NPT605	Organism	Homo sapiens	Homo sapiens	DILI_severity_class	=	0.0	n.a.	PMID[474576]
NPT2	Others	Unspecified		IC50	=	210.0	nM	PMID[474577]
NPT20555	ORGANISM	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	Hit score	=	-0.08012	n.a.	PMID[474578]
NPT27	Others	Unspecified		AUC Ratio	=	0.3082	n.a.	PMID[474579]
NPT20555	ORGANISM	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	AUC	=	601.9	n.a.	PMID[474579]
NPT22224	CELL-LINE	Vero C1008	Chlorocebus sabaeus	AUC cytotoxicity	=	185.5	n.a.	PMID[474579]
NPT22224	CELL-LINE	Vero C1008	Chlorocebus sabaeus	pCC50	~	6.987	n.a.	PMID[474579]
NPT20555	ORGANISM	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	IC50	~	213.8	nM	PMID[474579]
NPT25189	CELL-LINE	CT26.WT	Mus musculus	IC50	=	126.0	nM	PMID[474580]
NPT2	Others	Unspecified		IC50	=	93.6	nM	PMID[474580]
NPT2	Others	Unspecified		IC50	=	44.3	nM	PMID[474580]
NPT2	Others	Unspecified		IC50	=	26.7	nM	PMID[474580]
NPT2	Others	Unspecified		IC50	=	25.8	nM	PMID[474580]
NPT27	Others	Unspecified		Inhibition	=	28.0	%	PMID[474580]
NPT2	Others	Unspecified		Kb	=	6.3	10'5/M	PMID[474583]
NPT2	Others	Unspecified		Kb	=	1.3	10'5/M	PMID[474583]
NPT25189	CELL-LINE	CT26.WT	Mus musculus	IC50	=	420.0	nM	PMID[474585]
NPT2	Others	Unspecified		Ratio IC50	=	0.3	n.a.	PMID[474585]
NPT2	Others	Unspecified		Ratio IC50	=	0.2	n.a.	PMID[474585]
NPT20556	SINGLE PROTEIN	Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	Inhibition	=	28.27	%	PMID[474586]
NPT20555	ORGANISM	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	Inhibition	=	5.82	%	PMID[474587]
NPT20555	ORGANISM	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	IC50	>	20000.0	nM	PMID[474588]
NPT20555	ORGANISM	SARS-CoV-2	Severe acute respiratory syndrome coronavirus 2	IC50	>	19952.62	nM	PMID[474588]

☑ Note for Activity Records:
☉ The quantitative biological activities were primarily integrated from ChEMBL (Version-30) database and were also directly collected from PubMed literature. PubMed PMID was provided as the reference link for each activity record.

Chemically structural similarity: I. Similar Active Natural Products in NPASS

Top-200 similar NPs were calculated against the active-NP-set (includes 4,3285 NPs with experimentally-derived bioactivity available in NPASS)

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

● The left chart: Distribution of similarity level between NPC109403 and all remaining natural products in the NPASS database.
● The right table: Most similar natural products (Tc>=0.56 or Top200).

range	Tanimoto Coefficient
0-0.1	298
0.1-0.2	1329
0.2-0.3	3586
0.3-0.4	9268
0.4-0.5	9208
0.5-0.6	5993
0.6-0.7	7971
0.7-0.8	4876
0.8-0.85	135
0.85-0.9	26
0.9-0.95	0
0.95-1	7

Similarity Score	Similarity Level	Natural Product ID
1.0	High Similarity	NPC314738
1.0	High Similarity	NPC261012
0.9887	High Similarity	NPC315351
0.9887	High Similarity	NPC316412
0.8978	High Similarity	NPC42286
0.893	High Similarity	NPC313274
0.8802	High Similarity	NPC315889
0.8771	High Similarity	NPC478021
0.8757	High Similarity	NPC478020
0.8757	High Similarity	NPC478022
0.8743	High Similarity	NPC314941
0.8743	High Similarity	NPC315221
0.8722	High Similarity	NPC294501
0.8696	High Similarity	NPC313452
0.8673	High Similarity	NPC315253
0.8587	High Similarity	NPC153578
0.8587	High Similarity	NPC114257
0.8587	High Similarity	NPC277710
0.8587	High Similarity	NPC299149
0.8579	High Similarity	NPC102053
0.8579	High Similarity	NPC475246
0.8571	High Similarity	NPC85368
0.8531	High Similarity	NPC284495
0.8525	High Similarity	NPC3718
0.8516	High Similarity	NPC5029
0.8516	High Similarity	NPC271385
0.8516	High Similarity	NPC111536
0.8516	High Similarity	NPC76128
0.8516	High Similarity	NPC30432
0.8486	Intermediate Similarity	NPC58538
0.8478	Intermediate Similarity	NPC475233
0.8478	Intermediate Similarity	NPC46958
0.847	Intermediate Similarity	NPC203751
0.8466	Intermediate Similarity	NPC314672
0.8441	Intermediate Similarity	NPC477860
0.8441	Intermediate Similarity	NPC475161
0.8438	Intermediate Similarity	NPC108487
0.8436	Intermediate Similarity	NPC278329
0.8436	Intermediate Similarity	NPC101116
0.8436	Intermediate Similarity	NPC146837
0.8436	Intermediate Similarity	NPC212099
0.8424	Intermediate Similarity	NPC470667
0.8424	Intermediate Similarity	NPC186800
0.8424	Intermediate Similarity	NPC68381
0.8407	Intermediate Similarity	NPC175477
0.8407	Intermediate Similarity	NPC222455
0.8404	Intermediate Similarity	NPC87583
0.8382	Intermediate Similarity	NPC252156
0.8378	Intermediate Similarity	NPC289876
0.837	Intermediate Similarity	NPC199357
0.837	Intermediate Similarity	NPC98776
0.837	Intermediate Similarity	NPC472054
0.8361	Intermediate Similarity	NPC470580
0.836	Intermediate Similarity	NPC105591
0.8351	Intermediate Similarity	NPC224557
0.8351	Intermediate Similarity	NPC292706
0.8343	Intermediate Similarity	NPC329647
0.8343	Intermediate Similarity	NPC470735
0.8343	Intermediate Similarity	NPC178281
0.8342	Intermediate Similarity	NPC133775
0.8324	Intermediate Similarity	NPC19056
0.8324	Intermediate Similarity	NPC470583
0.8316	Intermediate Similarity	NPC205721
0.8315	Intermediate Similarity	NPC270027
0.8315	Intermediate Similarity	NPC183441
0.8306	Intermediate Similarity	NPC246274
0.8289	Intermediate Similarity	NPC212290
0.8289	Intermediate Similarity	NPC72783
0.8261	Intermediate Similarity	NPC298778
0.8256	Intermediate Similarity	NPC131405
0.8251	Intermediate Similarity	NPC103633
0.8251	Intermediate Similarity	NPC63470
0.8245	Intermediate Similarity	NPC197357
0.8245	Intermediate Similarity	NPC85316
0.8235	Intermediate Similarity	NPC470582
0.8235	Intermediate Similarity	NPC115447
0.8235	Intermediate Similarity	NPC470581
0.8235	Intermediate Similarity	NPC266513
0.8232	Intermediate Similarity	NPC216752
0.8232	Intermediate Similarity	NPC97637
0.8232	Intermediate Similarity	NPC187934
0.8226	Intermediate Similarity	NPC70862
0.8226	Intermediate Similarity	NPC199533
0.8226	Intermediate Similarity	NPC470454
0.8226	Intermediate Similarity	NPC146803
0.8216	Intermediate Similarity	NPC315619
0.8212	Intermediate Similarity	NPC206641
0.8212	Intermediate Similarity	NPC208651
0.8207	Intermediate Similarity	NPC259905
0.8207	Intermediate Similarity	NPC137460
0.8201	Intermediate Similarity	NPC478001
0.8201	Intermediate Similarity	NPC329790
0.8197	Intermediate Similarity	NPC178851
0.8191	Intermediate Similarity	NPC245059
0.8191	Intermediate Similarity	NPC84494
0.8191	Intermediate Similarity	NPC187441
0.8191	Intermediate Similarity	NPC283980
0.8182	Intermediate Similarity	NPC176246
0.8172	Intermediate Similarity	NPC470336
0.8172	Intermediate Similarity	NPC470438
0.8172	Intermediate Similarity	NPC470335
0.8172	Intermediate Similarity	NPC213052
0.8167	Intermediate Similarity	NPC53139
0.8148	Intermediate Similarity	NPC470448
0.8148	Intermediate Similarity	NPC164047
0.8148	Intermediate Similarity	NPC470453
0.8148	Intermediate Similarity	NPC208069
0.8148	Intermediate Similarity	NPC470452
0.8142	Intermediate Similarity	NPC297404
0.8142	Intermediate Similarity	NPC11608
0.8138	Intermediate Similarity	NPC470334
0.8138	Intermediate Similarity	NPC83331
0.8128	Intermediate Similarity	NPC474345
0.8118	Intermediate Similarity	NPC473113
0.8115	Intermediate Similarity	NPC241847
0.8111	Intermediate Similarity	NPC177742
0.8105	Intermediate Similarity	NPC475662
0.8105	Intermediate Similarity	NPC293227
0.8105	Intermediate Similarity	NPC473717
0.8105	Intermediate Similarity	NPC473631
0.8103	Intermediate Similarity	NPC314687
0.8101	Intermediate Similarity	NPC3449
0.8093	Intermediate Similarity	NPC314459
0.8093	Intermediate Similarity	NPC470199
0.8087	Intermediate Similarity	NPC183672
0.8085	Intermediate Similarity	NPC198893
0.8085	Intermediate Similarity	NPC232818
0.8085	Intermediate Similarity	NPC314489
0.8085	Intermediate Similarity	NPC272656
0.8075	Intermediate Similarity	NPC65118
0.8075	Intermediate Similarity	NPC154986
0.8065	Intermediate Similarity	NPC241874
0.8056	Intermediate Similarity	NPC283480
0.8056	Intermediate Similarity	NPC148323
0.8054	Intermediate Similarity	NPC470341
0.8054	Intermediate Similarity	NPC324522
0.8054	Intermediate Similarity	NPC473094
0.8054	Intermediate Similarity	NPC234497
0.8054	Intermediate Similarity	NPC472058
0.8054	Intermediate Similarity	NPC105414
0.8043	Intermediate Similarity	NPC478026
0.8043	Intermediate Similarity	NPC472049
0.8042	Intermediate Similarity	NPC168584
0.8042	Intermediate Similarity	NPC47191
0.8041	Intermediate Similarity	NPC48474
0.8033	Intermediate Similarity	NPC131745
0.8033	Intermediate Similarity	NPC259834
0.8033	Intermediate Similarity	NPC478229
0.8032	Intermediate Similarity	NPC307754
0.8032	Intermediate Similarity	NPC108202
0.8032	Intermediate Similarity	NPC63105
0.8032	Intermediate Similarity	NPC223735
0.8021	Intermediate Similarity	NPC475352
0.8021	Intermediate Similarity	NPC221140
0.8021	Intermediate Similarity	NPC477836
0.8021	Intermediate Similarity	NPC475220
0.8021	Intermediate Similarity	NPC473686
0.8021	Intermediate Similarity	NPC229817
0.802	Intermediate Similarity	NPC316164
0.8011	Intermediate Similarity	NPC473202
0.8011	Intermediate Similarity	NPC473096
0.8011	Intermediate Similarity	NPC473095
0.801	Intermediate Similarity	NPC470200
0.801	Intermediate Similarity	NPC470196
0.801	Intermediate Similarity	NPC470197
0.801	Intermediate Similarity	NPC470194
0.801	Intermediate Similarity	NPC470195
0.801	Intermediate Similarity	NPC282474
0.801	Intermediate Similarity	NPC470193
0.801	Intermediate Similarity	NPC316274
0.801	Intermediate Similarity	NPC470198
0.8	Intermediate Similarity	NPC174599
0.8	Intermediate Similarity	NPC82190
0.8	Intermediate Similarity	NPC192219
0.8	Intermediate Similarity	NPC70441
0.7989	Intermediate Similarity	NPC156635
0.7989	Intermediate Similarity	NPC17432
0.7989	Intermediate Similarity	NPC278419
0.7989	Intermediate Similarity	NPC92403
0.7989	Intermediate Similarity	NPC76112
0.7989	Intermediate Similarity	NPC66820
0.7989	Intermediate Similarity	NPC170018
0.7989	Intermediate Similarity	NPC66087
0.7989	Intermediate Similarity	NPC179198
0.7978	Intermediate Similarity	NPC73148
0.7969	Intermediate Similarity	NPC148710
0.7968	Intermediate Similarity	NPC8704
0.7968	Intermediate Similarity	NPC287884
0.7968	Intermediate Similarity	NPC313304
0.7968	Intermediate Similarity	NPC105511
0.7968	Intermediate Similarity	NPC44558
0.7967	Intermediate Similarity	NPC324736
0.7967	Intermediate Similarity	NPC231475
0.7967	Intermediate Similarity	NPC57072
0.7959	Intermediate Similarity	NPC314020
0.7957	Intermediate Similarity	NPC225419
0.795	Intermediate Similarity	NPC314946
0.7949	Intermediate Similarity	NPC264302
0.7947	Intermediate Similarity	NPC478000
0.7947	Intermediate Similarity	NPC477683

Chemically structural similarity: II. Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

● The left chart: Distribution of similarity level between NPC109403 and all drugs/candidates.
● The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

range	Tanimoto Coefficient
0-0.1	216
0.1-0.2	697
0.2-0.3	1505
0.3-0.4	2529
0.4-0.5	2345
0.5-0.6	1261
0.6-0.7	471
0.7-0.8	90
0.8-0.85	3
0.85-0.9	10
0.9-0.95	8
0.95-1	15

Similarity Score	Similarity Level	Drug ID	Developmental Stage
1.0	High Similarity	NPD6776	Approved
1.0	High Similarity	NPD6782	Approved
1.0	High Similarity	NPD6781	Approved
1.0	High Similarity	NPD6780	Approved
1.0	High Similarity	NPD6779	Approved
1.0	High Similarity	NPD6778	Approved
1.0	High Similarity	NPD6777	Approved
0.9724	High Similarity	NPD7696	Phase 3
0.9724	High Similarity	NPD7697	Approved
0.9724	High Similarity	NPD7698	Approved
0.9718	High Similarity	NPD6534	Approved
0.9718	High Similarity	NPD6535	Approved
0.967	High Similarity	NPD7871	Phase 2
0.967	High Similarity	NPD7870	Phase 2
0.9556	High Similarity	NPD7700	Phase 2
0.9556	High Similarity	NPD7699	Phase 2
0.9465	High Similarity	NPD7801	Approved
0.9402	High Similarity	NPD7435	Discontinued
0.9348	High Similarity	NPD6823	Phase 2
0.9202	High Similarity	NPD7701	Phase 2
0.9105	High Similarity	NPD7875	Clinical (unspecified phase)
0.9105	High Similarity	NPD7874	Approved
0.9031	High Similarity	NPD8155	Clinical (unspecified phase)
0.8859	High Similarity	NPD7879	Clinical (unspecified phase)
0.8763	High Similarity	NPD7783	Phase 2
0.8763	High Similarity	NPD7782	Clinical (unspecified phase)
0.8743	High Similarity	NPD8320	Phase 1
0.8743	High Similarity	NPD8319	Approved
0.8621	High Similarity	NPD8058	Clinical (unspecified phase)
0.8621	High Similarity	NPD8059	Phase 3
0.861	High Similarity	NPD6214	Clinical (unspecified phase)
0.861	High Similarity	NPD6212	Phase 3
0.861	High Similarity	NPD6213	Phase 3
0.8601	High Similarity	NPD7211	Clinical (unspecified phase)
0.8376	Intermediate Similarity	NPD8151	Discontinued
0.8148	Intermediate Similarity	NPD8150	Discontinued
0.7989	Intermediate Similarity	NPD8313	Approved
0.7989	Intermediate Similarity	NPD8312	Approved
0.7914	Intermediate Similarity	NPD7804	Clinical (unspecified phase)
0.7902	Intermediate Similarity	NPD7930	Approved
0.7814	Intermediate Similarity	NPD4381	Clinical (unspecified phase)
0.7784	Intermediate Similarity	NPD8397	Clinical (unspecified phase)
0.7766	Intermediate Similarity	NPD3751	Discontinued
0.7749	Intermediate Similarity	NPD4338	Clinical (unspecified phase)
0.7739	Intermediate Similarity	NPD7237	Clinical (unspecified phase)
0.7737	Intermediate Similarity	NPD6797	Phase 2
0.7696	Intermediate Similarity	NPD6559	Discontinued
0.7696	Intermediate Similarity	NPD7251	Discontinued
0.7688	Intermediate Similarity	NPD6959	Discontinued
0.7685	Intermediate Similarity	NPD7999	Approved
0.7684	Intermediate Similarity	NPD7074	Phase 3
0.768	Intermediate Similarity	NPD4380	Phase 2
0.7656	Intermediate Similarity	NPD7808	Phase 3
0.7647	Intermediate Similarity	NPD3787	Discontinued
0.7632	Intermediate Similarity	NPD7054	Approved
0.7592	Intermediate Similarity	NPD7472	Approved
0.7579	Intermediate Similarity	NPD3818	Discontinued
0.7566	Intermediate Similarity	NPD6167	Clinical (unspecified phase)
0.7566	Intermediate Similarity	NPD6168	Clinical (unspecified phase)
0.7566	Intermediate Similarity	NPD6166	Phase 2
0.7553	Intermediate Similarity	NPD6232	Discontinued
0.7539	Intermediate Similarity	NPD5844	Phase 1
0.7527	Intermediate Similarity	NPD7075	Discontinued
0.7526	Intermediate Similarity	NPD7473	Discontinued
0.7476	Intermediate Similarity	NPD7584	Approved
0.7475	Intermediate Similarity	NPD8285	Discontinued
0.7449	Intermediate Similarity	NPD8055	Clinical (unspecified phase)
0.7419	Intermediate Similarity	NPD5402	Approved
0.7366	Intermediate Similarity	NPD7096	Clinical (unspecified phase)
0.7366	Intermediate Similarity	NPD7819	Suspended
0.7366	Intermediate Similarity	NPD2393	Clinical (unspecified phase)
0.7337	Intermediate Similarity	NPD3226	Approved
0.7337	Intermediate Similarity	NPD8361	Approved
0.7337	Intermediate Similarity	NPD8360	Approved
0.7312	Intermediate Similarity	NPD6801	Discontinued
0.7296	Intermediate Similarity	NPD5034	Approved
0.7296	Intermediate Similarity	NPD5028	Approved
0.7296	Intermediate Similarity	NPD5026	Approved
0.7296	Intermediate Similarity	NPD4954	Approved
0.7296	Intermediate Similarity	NPD4955	Approved
0.7296	Intermediate Similarity	NPD36	Approved
0.7292	Intermediate Similarity	NPD7784	Clinical (unspecified phase)
0.7282	Intermediate Similarity	NPD7993	Clinical (unspecified phase)
0.7277	Intermediate Similarity	NPD5710	Approved
0.7277	Intermediate Similarity	NPD5711	Approved
0.7268	Intermediate Similarity	NPD8470	Clinical (unspecified phase)
0.7268	Intermediate Similarity	NPD8486	Clinical (unspecified phase)
0.7263	Intermediate Similarity	NPD5494	Approved
0.725	Intermediate Similarity	NPD8435	Approved
0.7245	Intermediate Similarity	NPD8368	Discontinued
0.7245	Intermediate Similarity	NPD5030	Phase 2
0.7243	Intermediate Similarity	NPD7458	Discontinued
0.7243	Intermediate Similarity	NPD8404	Phase 2
0.7236	Intermediate Similarity	NPD5037	Approved
0.7236	Intermediate Similarity	NPD5038	Approved
0.7234	Intermediate Similarity	NPD8443	Clinical (unspecified phase)
0.7225	Intermediate Similarity	NPD6973	Clinical (unspecified phase)
0.7222	Intermediate Similarity	NPD8407	Phase 2
0.7219	Intermediate Similarity	NPD1934	Approved
0.7216	Intermediate Similarity	NPD7228	Approved
0.7213	Intermediate Similarity	NPD4378	Clinical (unspecified phase)
0.7202	Intermediate Similarity	NPD7852	Clinical (unspecified phase)
0.7196	Intermediate Similarity	NPD4868	Clinical (unspecified phase)
0.719	Intermediate Similarity	NPD7585	Approved
0.7189	Intermediate Similarity	NPD8366	Approved
0.7186	Intermediate Similarity	NPD5036	Approved
0.7181	Intermediate Similarity	NPD2801	Approved
0.7173	Intermediate Similarity	NPD4666	Phase 3
0.7166	Intermediate Similarity	NPD7411	Suspended
0.7151	Intermediate Similarity	NPD2651	Approved
0.7151	Intermediate Similarity	NPD2649	Approved
0.715	Intermediate Similarity	NPD8434	Phase 2
0.7143	Intermediate Similarity	NPD7583	Approved
0.7136	Intermediate Similarity	NPD8491	Approved
0.7128	Intermediate Similarity	NPD6844	Discontinued
0.7128	Intermediate Similarity	NPD7177	Discontinued
0.7123	Intermediate Similarity	NPD5619	Clinical (unspecified phase)
0.7122	Intermediate Similarity	NPD8485	Approved
0.7121	Intermediate Similarity	NPD4419	Clinical (unspecified phase)
0.712	Intermediate Similarity	NPD7410	Clinical (unspecified phase)
0.712	Intermediate Similarity	NPD5709	Phase 3
0.712	Intermediate Similarity	NPD2533	Approved
0.712	Intermediate Similarity	NPD2532	Approved
0.712	Intermediate Similarity	NPD2534	Approved
0.7113	Intermediate Similarity	NPD4575	Clinical (unspecified phase)
0.7112	Intermediate Similarity	NPD6599	Discontinued
0.7105	Intermediate Similarity	NPD3882	Suspended
0.7101	Intermediate Similarity	NPD7501	Clinical (unspecified phase)
0.709	Intermediate Similarity	NPD8455	Phase 2
0.7085	Intermediate Similarity	NPD5035	Approved
0.7065	Intermediate Similarity	NPD7390	Discontinued
0.7065	Intermediate Similarity	NPD3863	Clinical (unspecified phase)
0.7056	Intermediate Similarity	NPD2935	Discontinued
0.7053	Intermediate Similarity	NPD3817	Phase 2
0.7043	Intermediate Similarity	NPD5403	Approved
0.7037	Intermediate Similarity	NPD37	Approved
0.7032	Intermediate Similarity	NPD7907	Approved
0.7031	Intermediate Similarity	NPD6234	Discontinued
0.7027	Intermediate Similarity	NPD4661	Approved
0.7027	Intermediate Similarity	NPD4662	Approved
0.702	Intermediate Similarity	NPD3823	Discontinued
0.7018	Intermediate Similarity	NPD4665	Approved
0.7018	Intermediate Similarity	NPD4111	Phase 1
0.7017	Intermediate Similarity	NPD2346	Discontinued
0.7016	Intermediate Similarity	NPD4965	Approved
0.7016	Intermediate Similarity	NPD4967	Phase 2
0.7016	Intermediate Similarity	NPD4966	Approved
0.7	Intermediate Similarity	NPD1509	Clinical (unspecified phase)
0.7	Intermediate Similarity	NPD7497	Discontinued
0.6986	Remote Similarity	NPD2493	Approved
0.6986	Remote Similarity	NPD2494	Approved
0.6985	Remote Similarity	NPD5031	Approved
0.6985	Remote Similarity	NPD7039	Approved
0.6985	Remote Similarity	NPD5027	Approved
0.6985	Remote Similarity	NPD5029	Approved
0.6985	Remote Similarity	NPD7038	Approved
0.6985	Remote Similarity	NPD7685	Pre-registration
0.698	Remote Similarity	NPD8424	Clinical (unspecified phase)
0.6979	Remote Similarity	NPD3749	Approved
0.6978	Remote Similarity	NPD1549	Phase 2
0.6973	Remote Similarity	NPD6799	Approved
0.6968	Remote Similarity	NPD5808	Clinical (unspecified phase)
0.6961	Remote Similarity	NPD3808	Clinical (unspecified phase)
0.6954	Remote Similarity	NPD2163	Approved
0.6952	Remote Similarity	NPD5006	Approved
0.6952	Remote Similarity	NPD5005	Approved
0.6942	Remote Similarity	NPD4363	Phase 3
0.6942	Remote Similarity	NPD4360	Phase 2
0.6935	Remote Similarity	NPD5401	Approved
0.6933	Remote Similarity	NPD8067	Phase 3
0.6927	Remote Similarity	NPD7768	Phase 2
0.6923	Remote Similarity	NPD1550	Clinical (unspecified phase)
0.6923	Remote Similarity	NPD4420	Approved
0.6923	Remote Similarity	NPD1552	Clinical (unspecified phase)
0.6919	Remote Similarity	NPD3300	Phase 2
0.6906	Remote Similarity	NPD1510	Phase 2
0.6905	Remote Similarity	NPD3450	Approved
0.6905	Remote Similarity	NPD3452	Approved
0.6902	Remote Similarity	NPD1878	Clinical (unspecified phase)
0.6902	Remote Similarity	NPD4628	Phase 3
0.69	Remote Similarity	NPD7240	Approved
0.69	Remote Similarity	NPD5039	Approved
0.6898	Remote Similarity	NPD1512	Approved
0.6889	Remote Similarity	NPD1607	Approved
0.6887	Remote Similarity	NPD4583	Approved
0.6887	Remote Similarity	NPD4582	Approved
0.6875	Remote Similarity	NPD2974	Approved
0.6875	Remote Similarity	NPD2975	Approved
0.6875	Remote Similarity	NPD2973	Approved
0.6865	Remote Similarity	NPD6190	Approved
0.6844	Remote Similarity	NPD7654	Discontinued
0.684	Remote Similarity	NPD4004	Approved
0.684	Remote Similarity	NPD4002	Approved
0.6823	Remote Similarity	NPD1465	Phase 2
0.6809	Remote Similarity	NPD2675	Approved
0.6809	Remote Similarity	NPD2676	Approved
0.6802	Remote Similarity	NPD7184	Clinical (unspecified phase)
0.68	Remote Similarity	NPD8469	Approved
0.68	Remote Similarity	NPD4956	Approved
0.6794	Remote Similarity	NPD7282	Approved

Bioactivity similarity: Similar Natural Products in NPASS

Bioactivity similarity was calculated based on bioactivity descriptors of compounds. The bioactivity descriptors were calculated by a recently developed AI algorithm Chemical Checker (CC) [Nature Biotechnology, 38:1087–1096, 2020; Nature Communications, 12:3932, 2021], which evaluated bioactivity similarities at five levels:
☉ A: chemistry similarity;
☉ B: biological targets similarity;
☉ C: networks similarity;
☉ D: cell-based bioactivity similarity;
☉ E: similarity based on clinical data.

Those 5 categories of CC bioactivity descriptors were calculated and then subjected to manifold projection using UMAP algorithm, to project all NPs on a 2-Dimensional space. The current NP was highlighted with a small circle in the 2-D map. Below figures: left-to-right, A-to-E.

A: chemistry similarity

B: biological targets similarity

C: networks similarity

D: cell-based bioactivity similarity

E: similarity based on clinical data