Plant ID: NPO1074
Plant Latin Name: Hydrastis Canadensis
Taxonomy Genus: Hydrastis
Taxonomy Family: Ranunculaceae
NCBI TaxonomyDB:
13569
Plant-of-the-World-Online:
n.a.
Antibacterial; Antiperiodic; Antiseptic; Antispasmodic; Astringent; Cholagogue; Diuretic; Laxative; Sedative; Stomachic; Tonic
Canada; United States; Belarus; China
Ingredient ID: NPC93989
Ingredient ID: NPC73020
Ingredient ID: NPC54379
Ingredient ID: NPC53069
Ingredient ID: NPC482982
Ingredient ID: NPC478985
Ingredient ID: NPC477259
Ingredient ID: NPC477258
Ingredient ID: NPC308036
Ingredient ID: NPC296482
Ingredient ID: NPC27887
Ingredient ID: NPC269699
Ingredient ID: NPC24228
Ingredient ID: NPC216459
Ingredient ID: NPC183485
Ingredient ID: NPC170826
Ingredient ID: NPC167084
Ingredient ID: NPC159275
Ingredient ID: NPC14622
Ingredient ID: NPC138487
Ingredient ID: NPC136330
Ingredient ID: NPC122483
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Cytochrome P450 | Cytochrome P450 family 1 | CYP1B1 | Cytochrome P450 1B1 | Q16678 | CHEMBL4878 |
Cytochrome P450 | Cytochrome P450 family 2 | CYP2D6 | Cytochrome P450 2D6 | P10635 | CHEMBL289 |
Therapeutic Target | Hydrolase | ACHE | Acetylcholinesterase | P22303 | CHEMBL220 |
Therapeutic Target | Oxidoreductase | MAOB | Monoamine oxidase B | P27338 | CHEMBL2039 |
Therapeutic Target | Small molecule receptor (family A GPCR) | DRD3 | Dopamine D3 receptor | P35462 | CHEMBL234 |
Therapeutic Target | Small molecule receptor (family A GPCR) | DRD5 | Dopamine D5 receptor | P21918 | CHEMBL1850 |
Therapeutic Target | Small molecule receptor (family A GPCR) | DRD2 | Dopamine D2 receptor | P14416 | CHEMBL217 |
Therapeutic Target | Small molecule receptor (family A GPCR) | DRD1 | Dopamine D1 receptor | P21728 | CHEMBL2056 |
Therapeutic Target | Small molecule receptor (family A GPCR) | DRD4 | Dopamine D4 receptor | P21917 | CHEMBL219 |
Therapeutic Target | Small molecule receptor (family A GPCR) | ADRA2B | Alpha-2b adrenergic receptor | P18089 | CHEMBL1942 |
Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 15 | |
Plant level | 1 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT00425009 | Therapeutic Effects of Berberine in Patients With Type 2 Diabetes | type 2 diabetes mellitus | Berberine (NPC53069) | NP level |
NCT02548832 | Bezafibrate Plus Berberine in Mixed Dyslipidemia | Combined hyperlipidemia | Berberine (NPC53069) | NP level |
NCT02365480 | Berberine Chloride in Preventing Colorectal Cancer in Patients With Ulcerative Colitis in Remission | ulcerative colitis | Berberine Chloride (NPC296482) | NP level |
NCT02861261 | A Study on the Efficacy and Gut Microbiota of Berberine and Probiotics in Patients With Newly Diagnosed Type 2 Diabetes | type 2 diabetes mellitus | Berberine (NPC53069) | NP level |
NCT02082756 | Effects of Berberine Hydrochloride and Bifidobacterium in Prediabetes Prevention and Treatment | prediabetes syndrome | Berberine (NPC53069) | NP level |
NCT02084004 | Effects of Berberine Hydrochloride and Bifidobacterium in Diabetes Mellitus Prevention and Treatment | type 2 diabetes mellitus | Berberine (NPC53069) | NP level |
NCT03333265 | Primary Chemoprevention of Familial Adenomatous Polyposis With Berberine Hydrochloride | colorectal adenoma | Berberine (NPC53069) | NP level |
NCT00633282 | Role of Pioglitazone and Berberine in Treatment of Non-Alcoholic Fatty Liver Disease | non-alcoholic fatty liver disease | Berberine (NPC53069) | NP level |
NCT03972215 | Berberine Hyperglycemic Clamp | diabetes mellitus | Berberine Chloride (NPC296482) | NP level |
NCT03486496 | Gefitinib and Berberine in the First-line Treatment of Lung Adenocarcinoma With EGFR Mutation | lung adenocarcinoma | Berberine (NPC53069) | NP level |
NCT03772262 | Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail Approach | Interaction Drug Food | Hydrastis Canadensis | Plant level As single plant |
NCT05430087 | Vitamin D and Curcumin Piperine Attenuates Disease Activity and Cytokine Levels in Systemic Lupus Erythematosus Patients | systemic lupus erythematosus | Piperine (NPC136330) | NP level |
NCT02226185 | Study of Berberine Hydrochloride in Prevention of Colorectal Adenomas Recurrence | colorectal adenoma | Berberine (NPC53069) | NP level |
NCT03281096 | A Research of Berberine Hydrochloride to Prevent Colorectal Adenomas in Patients With Previous Colorectal Cancer | colorectal adenoma | Berberine (NPC53069) | NP level |
NCT01383694 | Effect Of Piperine In Patients With Oropharyngeal Dysphagia | Dysphagia | Piperine (NPC136330) | NP level |
NCT01893424 | Bioequivalence Assessment of Oral Administration Vs. Oral Spray of a Cannabinoids (Tetrahydrocannabinol and Cannabidiol) | pain | Piperine (NPC136330) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
DRD4,MAOB,ADRA2C,DRD3,CHRM1,SIGMAR1,DRD2,ACHE
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
DRD1,DRD2,DRD3,CHRM1,ACHE,DRD4,SIGMAR1,MAOB
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
DRD1,DRD2,CHRM1,SIGMAR1,DRD4,DRD3
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
ADRA2C,SIGMAR1,DRD2,ACHE,ADRA2B
NCT01893424 |
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
CYP1B1,MAOB,DRD1,ACHE,LMNA,DRD2
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
CHRM1,ADRA2B,DRD2,MAOB,ADRA2C
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
ADRA2C,DRD2,DRD1,DRD2,MAOB
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
MAOB,DRD2,DRD3,DRD4,SIGMAR1
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
DRD2,ADRA2C,SIGMAR1,CHRM1,DRD5
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
MAOB,ACHE,ADRA2C,LMNA,SIGMAR1
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
ADRA2B,ACHE,ADRA2C,CHRM1,DRD2
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
CYP1B1,DRD1,ACHE,ADRA2C,DRD2
|
Psychotic disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20-6A25 |
DRD1,SIGMAR1,DRD2,DRD4
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
ADRA2C,ACHE,DRD2,CHRM1
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
MAOB,CHRM1,DRD1,ACHE
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
ACHE,DRD2,ADRA2B,ADRA2C
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
DRD2
NCT02861261,NCT00425009,NCT02084004 |
Allergic/hypersensitivity disorderDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A80-4A8Z |
DRD4,DRD2,DRD1,DRD5
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
ADRA2B,ACHE,DRD2
NCT05430087 |
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
DRD2,CHRM1,DRD5,ACHE
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
DRD1,LMNA,SIGMAR1,DRD2
|
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
DRD3,DRD4,DRD2
|
Sexual dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA00-HA01 |
SIGMAR1,DRD2,DRD3
|
Bipolar disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60 |
DRD2,DRD4,DRD3
|
Intellectual development disorderDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD90 |
CHRM1,SIGMAR1,DRD2
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
DRD2,CHRM1,DRD3
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
ACHE,SIGMAR1,CHRM1
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
NCT02226185,NCT03333265,NCT03281096
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
DRD4,ADRA2C,LMNA
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
ADRA2B,DRD2,DRD4
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
ADRA2C,DRD1,ACHE
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
SIGMAR1,CHRM1
|
Gastroduodenal motor/secretory disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA41 |
DRD2,DRD3
|
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
DRD2,DRD3
|
MigraineDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80 |
MAOB,DRD2
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
DRD2,DRD3
|
HypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA20-BA21 |
DRD2,ADRA2C
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
CHRM1,ADRA2C
|
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
DRD3,DRD2
|
Epileptic encephalopathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A62 |
CHRM1,SIGMAR1
|
Acute upper respiratory infectionDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA07 |
DRD3,DRD2
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
DRD2,DRD3
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
DRD2,ADRA2C
|
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
MAOB,CYP2D6
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
MAOB,DRD2
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
DRD2,DRD3
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
DRD2,CYP2D6
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
DRD2,DRD3
|
Schizoaffective disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A21 |
CHRM1,DRD2
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
CHRM1,DRD5
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
ADRA2C,DRD5
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
DRD5,DRD4
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
ACHE,DRD4
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
ADRA2C,DRD4
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
LMNA,ACHE
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
CYP1B1,ADRA2C
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
CYP2D6,ACHE
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
LMNA,ADRA2B
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
CYP1B1,LMNA
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
DRD2,CHRM1
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
CYP1B1,ADRA2B
|
Drug or substance interactions without injury or harmDisease Category: 24.Factors influencing health status or contact with health servicesDisease ICD-11 Code: QA79 |
NCT03772262
|
Post-traumatic stress disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B40 |
ADRA2C
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
DRD2
|
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
ADRA2C
|
Digestive system diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DE2Z |
DRD2
|
HyperaemiaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A61-9B7Y |
DRD2
|
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
SIGMAR1
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
ADRA2C
|
Restless legs syndromeDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A80 |
DRD2
|
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
DRD2
|
NADisease Category: NADisease ICD-11 Code: NA |
DRD2
|
GangreneDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MC85 |
DRD2
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
ADRA2C
|
PediculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G00 |
ACHE
|
Cocaine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C45 |
DRD1
|
Corneal diseaseDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A76-9A78 |
CHRM1
|
CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
SIGMAR1
|
Unspecific substance harmful effectDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE6Z |
ACHE
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
DRD2
|
Dissociative neurological symptom disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B60 |
ADRA2C
|
Abdominal pelvic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD81 |
CHRM1
|
Vasomotor/allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08 |
ADRA2C
|
CoughDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD12 |
SIGMAR1
|
AbortionDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA00 |
DRD1
|
Psychoactive substances use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4G |
DRD3
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
DRD2
|
Myasthenia gravisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C6Y |
ACHE
|
Peptic ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA61 |
CHRM1
|
Postpartum haemorrhageDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA43 |
DRD2
|
Idiopathic interstitial pneumonitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03 |
DRD2
|
Abnormal micturitionDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MF50 |
CHRM1
|
ThyrotoxicosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A02 |
DRD2
|
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
DRD2
|
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
DRD2
|
Immune system diseaseDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A01-4B41 |
SIGMAR1
|
Central nervous system diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A04-8D87 |
SIGMAR1
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
DRD2
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
DRD2
|
Non-specific cutaneous vascular symptonDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME64 |
ADRA2C
|
Faecal incontinenceDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME07 |
DRD2
|
Primary psychotic disorder manifestationDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A25 |
MAOB
|
Oesophageal/gastroduodenal disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD90 |
ACHE
|
Mood disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60-6E23 |
SIGMAR1
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
MAOB
|
DyslipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80-5C81 |
CHRM1
|
Acquired hypomelanotic disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED63 |
MAOB
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
MAOB
|
HyperhidrosisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EE00 |
CHRM1
|
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
DRD3
|
Gastric ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA60 |
CHRM1
|
ItchingDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F28-1G07 |
DRD2
|
Skin cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30-2C37 |
MAOB
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
CHRM1
|
Inborn porphyrin/heme metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C58 |
DRD2
|
Neurobehavioral disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00-8A0Z |
SIGMAR1
|
Bulimia nervosaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B81 |
SIGMAR1
|
Functional bladder disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC50 |
CHRM1
|
Parasitic worm infestationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F90 |
ACHE
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
DRD2
|
Dystonic disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A02 |
CHRM1
|
Sebaceous gland disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED91 |
CHRM1
|
Breathing abnormalityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD11 |
DRD2
|
SomnolenceDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG42 |
SIGMAR1
|
Tic disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A05 |
DRD1
|
Skin tag/polypDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK71 |
MAOB
|
Endocrine gland neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F37 |
DRD2
|
Carcinoid syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B10 |
DRD2
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
CHRM1
|
Cerebral ischaemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B1Z |
DRD2
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
DRD2
|
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
NCT00633282
|
DysphagiaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD93 |
NCT01383694
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
NCT03972215
|
Intermediate hyperglycaemia, unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A40.Z |
NCT02082756
|
Ulcerative colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD71 |
NCT02365480
|
Mixed hyperlipidaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80.2 |
NCT02548832
|
AdenocarcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D40 |
NCT03486496
|
Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
ADRA2B
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
ACHE
|
Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
DRD3
|
Idiopathic pulmonary fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03.4 |
DRD5
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
DRD1
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
ACHE
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
DRD2
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
ACHE
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
CYP2D6
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
CYP1B1
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
ACHE
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
ADRA2C
|