Prescription Description
| Prescription ID | TCMFx676 |
| Pinyin Name | Song Ling Xue Mai Kang Jiao Nang |
| Chinese Name | 松龄血脉康胶囊 |
| English Name | Song Ling Xue Mai Kang Capsule |
| Function Description | 头痛, 眩晕, 急躁易怒, 心悸, 失眠; 高血压病及原发性高脂血症见上述证候者 |
| Indications | Vertigo disorder, Hypertension, Hyperlipidemia |
| Disease ICD-11 Category |
SD22 [Vertigo disorder (TM1), 眩晕 (TM1)
]; BA2Z [Hypotension, unspecified, 低血压，未特指的 ]; 5C80.Z [Hyperlipoproteinaemia, unspecified, 高脂蛋白血症，未特指的 ]; |
| Human Tissues Associated with Indication | Brain, Heart, Blood |
| Reference | Chinese pharmacopoeia (2015) |
| Reference Book/link | ISBN 978-7-5067-7337-9 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH2034 | NA | 松叶 | TCMH2034 | |
| TCMH677 | Pueraria lobata | 葛根 | TCMH677 | ITSAJ4206-14 |
| TCMH2608 | Margarita | 珍珠层粉 | TCMH2608 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
| TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
| TCMT236 | ESR2 | Estrogen receptor beta | Nuclear receptor | Q92731 |
| TCMT344 | AOX1 | Aldehyde oxidase | Oxidoreductase | Q06278 |
| TCMT591 | ESRRA | Estrogen-related receptor alpha | Nuclear receptor | P11474 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
| TCMT907 | FDPS | Farnesyl diphosphate synthase | Lyase | P14324 |
| TCMT910 | ESRRB | Estrogen-related receptor beta | Nuclear receptor | O95718 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1227 | Streptococcus |
| TCMT1246 | Escherichia coli |
| TCMT1284 | Penicillium expansum |
| TCMT1438 | Plasmodium falciparum |
| TCMT1442 | Leishmania donovani |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples