TCM Prescription: Ban Lan Gen Granules



Prescription Description
Prescription IDTCMFx675
Pinyin NameBan Lan Gen Ke Li 
Chinese Name板蓝根颗粒
English NameBan Lan Gen Granules
Function Description急性扁桃体炎
IndicationsPharyngotonsillitis
Disease ICD-11 Category CA0Y [Other specified upper respiratory tract disorders, 其他特指的上呼吸道疾患 ];
Human Tissues Associated with IndicationTonsil, Lung, Bronchus
ReferenceChinese pharmacopoeia (2015)
Reference Book/linkISBN 978-7-5067-7337-9
Prescription Components
Component ID Latin Name Chinese Name Component Quantity Barcode
TCMH127 Isatis indigotica 板蓝根 TCMH127 KJ765825
Reference: Chinese pharmacopoeia (2015)

Targeted Human Proteins by the Ingredients of Prescription

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT112 ADORA3 Adenosine A3 receptor GPCR P0DMS8
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT188 DHFR Dihydrofolate reductase Oxidoreductase P00374
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT296 ADORA1 Adenosine A1 receptor GPCR P30542
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT318 HKDC1 Putative hexokinase HKDC1 Transferase Q2TB90
TCMT336 IDO1 Indoleamine 2,3-dioxygenase Oxidoreductase P14902
TCMT597 SLC28A3 Solute carrier family 28 member 3 Transporter Q9HAS3
TCMT709 SLC28A2 Sodium/nucleoside cotransporter 2 Transporter O43868
TCMT710 SLC28A1 Sodium/nucleoside cotransporter 1 Transporter O00337
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603


Targeted Pathogenic Microbes by the Ingredients of Prescription

Target ID Target Name
TCMT1206 Influenza A virus (A/PR/8/34(H1N1))
TCMT1218 Staphylococcus aureus
TCMT1241 Human rhinovirus 14
TCMT1285 Human coxsackievirus B3
TCMT1296 Influenza A virus H3N2
TCMT1333 Human rhinovirus 1A
TCMT1347 Human rhinovirus 16
TCMT1348 Human rhinovirus 2
TCMT1353 Plasmodium yoelii
TCMT1361 Neisseria meningitidis
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1438 Plasmodium falciparum
TCMT1439 Mycobacterium smegmatis
TCMT1442 Leishmania donovani
TCMT1449 Influenza A virus
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Gene Ontology Associated to Targeted Human Proteins

GO Term GO Name Enriched Genes Log10 Adjusted P-value


KEGG Pathways Associated to Targeted Human Proteins

KEGG Pathway ID Enriched Genes Log10 Adjusted P-value


Target Exprsssion in Healthy Human Tissues (protein & mRNA level)

Protein expression data was from the "Human Proteome Map" dataset
mRNA expression data was from the "GTEx" dataset



Average Target Expression (Fold Change) in Multiple Disease Conditions

Fold Change with Corresponding Normal Samples
Click each cell within the heatmap to access gene expression of individual patient samples
Data Section
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1. General Information of Prescription  
2. Putative Targets  
3. Activity & References for Filtering Putative Targets  
4. GO & Pathway