Prescription Description
| Prescription ID | TCMFx6560 |
| Pinyin Name | Yi Pi Zhuang Shen San |
| Chinese Name | 益脾壮身散 |
| English Name | Yi Pi Zhuang Shen Powder |
| Function Description | 厌食 |
| Indications | Anorexia |
| Disease ICD-11 Category |
MG43.7 [Anorexia, 纳差
]; |
| Human Tissues Associated with Indication | Spleen, Stomach |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH606 | Wolfiporia cocos | 茯苓 | TCMH606 | GBPOL314-13 |
| TCMH62 | Lilium brownii | ç™¾åˆ | TCMH62 | ITSAO2415-14 |
| TCMH1430 | Hordeum vulgare | 麦芽 | TCMH1430 | ITSAI3101-14 |
| TCMH1307 | Massa medicata fermentata | å…神曲 | TCMH1307 | |
| TCMH1663 | Semen euryales | 芡实 | TCMH1663 | |
| TCMH147 | Glehnia littoralis | åŒ—æ²™å‚ | TCMH147 | ITSAF389-14 |
| TCMH1026 | Gallus gallus domesticus | 鸡内金 | TCMH1026 | ACLB009-06 |
| TCMH702 | Fructus setariae germinatus | 谷芽 | TCMH702 | |
| TCMH2486 | Coix lacryma- jobi var. ma - yuen | è–è‹¡ä» | TCMH2486 | |
| TCMH1845 | Dioscorea batatas | å±±è¯ | TCMH1845 | |
| TCMH1937 | Concha haliotidis | 石决明 | TCMH1937 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT159 | TYR | Tyrosinase | Oxidoreductase | P14679 |
| TCMT161 | HCAR2 | Hydroxycarboxylic acid receptor 2 | GPCR | Q8TDS4 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT206 | CYP2A6 | Cytochrome P450 2A6 | Oxidoreductase | P11509 |
| TCMT207 | BACE1 | Beta-secretase 1 | Protease | P56817 |
| TCMT212 | SRC | Tyrosine-protein kinase SRC | Kinase | P12931 |
| TCMT215 | CYP1A1 | Cytochrome P450 1A1 | Oxidoreductase | P04798 |
| TCMT217 | CYP2C8 | Cytochrome P450 2C8 | Oxidoreductase | P10632 |
| TCMT219 | CYP1A2 | Cytochrome P450 1A2 | Oxidoreductase | P05177 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT23 | ALPL | Alkaline phosphatase, tissue-nonspecific isozyme | Hydrolase | P05186 |
| TCMT239 | PIM1 | Serine/threonine-protein kinase PIM1 | Kinase | P11309 |
| TCMT257 | CYP1B1 | Cytochrome P450 1B1 | Oxidoreductase | Q16678 |
| TCMT260 | FLT3 | Tyrosine-protein kinase receptor FLT3 | Kinase | P36888 |
| TCMT261 | DAPK1 | Death-associated protein kinase 1 | Kinase | P53355 |
| TCMT268 | CYP2A13 | Cytochrome P450 2A13 | Oxidoreductase | Q16696 |
| TCMT295 | MMP1 | Matrix metalloproteinase-1 | Hydrolase | P03956 |
| TCMT296 | ADORA1 | Adenosine A1 receptor | GPCR | P30542 |
| TCMT297 | FABP4 | Fatty acid binding protein adipocyte | Unclassified | P15090 |
| TCMT298 | FABP3 | Fatty acid binding protein muscle | Hydrolase | P05413 |
| TCMT30 | PTGS2 | Cyclooxygenase-2 | Oxidoreductase | P35354 |
| TCMT306 | MMP2 | Matrix metalloproteinase-2 | Hydrolase | P08253 |
| TCMT315 | HTR6 | Serotonin 6 (5-HT6) receptor | GPCR | P50406 |
| TCMT321 | MMP9 | Matrix metalloproteinase 9 | Hydrolase | P14780 |
| TCMT322 | MMP13 | Matrix metalloproteinase 13 | Hydrolase | P45452 |
| TCMT327 | TRPV1 | Vanilloid receptor | Ion channel | Q8NER1 |
| TCMT335 | MPO | Myeloperoxidase | Oxidoreductase | P05164 |
| TCMT336 | IDO1 | Indoleamine 2,3-dioxygenase | Oxidoreductase | P14902 |
| TCMT369 | IGF1R | Insulin-like growth factor I receptor | Kinase | P08069 |
| TCMT370 | KDR | Vascular endothelial growth factor receptor 2 | Kinase | P35968 |
| TCMT374 | AURKB | Serine/threonine-protein kinase Aurora-B | Kinase | Q96GD4 |
| TCMT388 | AXL | Tyrosine-protein kinase receptor UFO | Kinase | P30530 |
| TCMT401 | MET | Hepatocyte growth factor receptor | Kinase | P08581 |
| TCMT422 | CAMK2B | CaM kinase II beta | Kinase | Q13554 |
| TCMT44 | GLO1 | Glyoxalase I | Lyase | Q04760 |
| TCMT445 | NEK2 | Serine/threonine-protein kinase NEK2 | Kinase | P51955 |
| TCMT462 | NEK6 | Serine/threonine-protein kinase NEK6 | Kinase | Q9HC98 |
| TCMT479 | AKT1 | Serine/threonine-protein kinase AKT | Kinase | P31749 |
| TCMT484 | PLK1 | Serine/threonine-protein kinase PLK1 | Kinase | P53350 |
| TCMT558 | TOP2A | DNA topoisomerase II alpha | Isomerase | P11388 |
| TCMT571 | ADORA2B | Adenosine A2b receptor | GPCR | P29275 |
| TCMT592 | XDH | Xanthine dehydrogenase | Oxidoreductase | P47989 |
| TCMT597 | SLC28A3 | Solute carrier family 28 member 3 | Transporter | Q9HAS3 |
| TCMT63 | PPARA | Peroxisome proliferator-activated receptor alpha | Nuclear receptor | Q07869 |
| TCMT66 | HSD17B2 | Estradiol 17-beta-dehydrogenase 2 | Oxidoreductase | P37059 |
| TCMT709 | SLC28A2 | Sodium/nucleoside cotransporter 2 | Transporter | O43868 |
| TCMT710 | SLC28A1 | Sodium/nucleoside cotransporter 1 | Transporter | O00337 |
| TCMT737 | APOBEC3G | DNA dC->dU-editing enzyme APOBEC-3G | Unclassified | Q9HC16 |
| TCMT740 | PIK3CG | PI3-kinase p110-gamma subunit | Transferase | P48736 |
| TCMT784 | AVPR2 | Vasopressin V2 receptor | GPCR | P30518 |
| TCMT785 | CXCR1 | Interleukin-8 receptor A | GPCR | P25024 |
| TCMT786 | CCR4 | C-C chemokine receptor type 4 | GPCR | P51679 |
| TCMT791 | PKN1 | Protein kinase N1 | Kinase | Q16512 |
| TCMT793 | PYGL | Liver glycogen phosphorylase | Transferase | P06737 |
| TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
| TCMT808 | FABP5 | Fatty acid binding protein epidermal | Unclassified | Q01469 |
| TCMT809 | FABP2 | Fatty acid binding protein intestinal | Unclassified | P12104 |
| TCMT810 | TLR2 | Toll-like receptor 2 | Unclassified | O60603 |
| TCMT822 | FUT7 | Alpha-(1,3)-fucosyltransferase 7 | Transferase | Q11130 |
| TCMT907 | FDPS | Farnesyl diphosphate synthase | Lyase | P14324 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1172 | Staphylococcus aureus subsp. aureus RN4220 |
| TCMT1174 | Mycobacterium bovis BCG |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1177 | Haemophilus influenzae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1179 | Escherichia coli ATCC 8739 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1182 | Streptococcus sanguinis |
| TCMT1184 | Mycobacterium fortuitum |
| TCMT1185 | Mycobacterium phlei |
| TCMT1187 | Enterococcus faecalis ATCC 29212 |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1191 | Bacillus megaterium |
| TCMT1192 | Bacteria |
| TCMT1193 | Staphylococcus |
| TCMT1194 | Shigella sonnei |
| TCMT1196 | Salmonella |
| TCMT1198 | Serratia marcescens |
| TCMT1199 | Streptococcus sp. 'group A' |
| TCMT1200 | Bacillus thuringiensis |
| TCMT1201 | Staphylococcus epidermidis ATCC 12228 |
| TCMT1202 | Mycoplasma hominis |
| TCMT1203 | Mycoplasma pneumoniae |
| TCMT1204 | Clostridium perfringens |
| TCMT1207 | Legionella pneumophila |
| TCMT1208 | Escherichia coli K12 |
| TCMT1209 | Staphylococcus haemolyticus |
| TCMT1211 | Fusobacterium nucleatum |
| TCMT1212 | Verticillium dahliae |
| TCMT1213 | Neisseria gonorrhoeae |
| TCMT1214 | Enterococcus faecium |
| TCMT1215 | Pseudomonas aeruginosa PAO1 |
| TCMT1216 | Vibrio cholerae |
| TCMT1217 | Bacillus anthracis |
| TCMT1218 | Staphylococcus aureus |
| TCMT1219 | Enterococcus |
| TCMT1220 | Streptococcus pneumoniae R6 |
| TCMT1222 | Plasmodium falciparum D6 |
| TCMT1223 | Staphylococcus epidermidis |
| TCMT1224 | Proteus mirabilis |
| TCMT1226 | Klebsiella pneumoniae |
| TCMT1227 | Streptococcus |
| TCMT1229 | Enterococcus faecalis |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1236 | Mycobacterium bovis |
| TCMT1237 | Mycobacterium kansasii |
| TCMT1243 | Aspergillus flavus |
| TCMT1244 | Staphylococcus saprophyticus |
| TCMT1245 | Phytophthora cactorum |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1252 | Alcaligenes faecalis |
| TCMT1253 | Penicillium chrysogenum |
| TCMT1260 | Streptococcus agalactiae |
| TCMT1262 | Mycoplasma putrefaciens |
| TCMT1266 | Mycobacterium abscessus |
| TCMT1267 | Mycobacterium chelonae |
| TCMT1271 | Shigella flexneri |
| TCMT1272 | Campylobacter jejuni |
| TCMT1273 | Pseudomonas putida |
| TCMT1274 | Shigella boydii |
| TCMT1276 | Klebsiella |
| TCMT1277 | Serratia |
| TCMT1278 | Pseudomonas |
| TCMT1281 | Clostridium difficile |
| TCMT1286 | Bacillus cereus |
| TCMT1287 | Bacillus subtilis subsp. spizizenii ATCC 6633 |
| TCMT1289 | Shigella dysenteriae |
| TCMT1290 | Acinetobacter calcoaceticus |
| TCMT1291 | Haemophilus parainfluenzae |
| TCMT1294 | Human parainfluenza virus 3 |
| TCMT1299 | Morganella morganii |
| TCMT1300 | Enterobacter |
| TCMT1301 | Klebsiella sp. |
| TCMT1303 | Bacillus |
| TCMT1304 | Staphylococcus capitis |
| TCMT1305 | Salmonella enteritidis |
| TCMT1307 | Penicillium marneffei |
| TCMT1309 | Aspergillus clavatus |
| TCMT1310 | Enterococcus hirae |
| TCMT1314 | Streptococcus viridans |
| TCMT1315 | Streptococcus sp. |
| TCMT1317 | Staphylococcus lentus |
| TCMT1321 | Staphylococcus hominis |
| TCMT1322 | Streptococcus mitis |
| TCMT1326 | Shigella |
| TCMT1331 | Acinetobacter sp. |
| TCMT1332 | Bacillus licheniformis |
| TCMT1334 | Chlamydia trachomatis |
| TCMT1340 | Staphylococcus faecalis |
| TCMT1341 | Streptococcus oralis |
| TCMT1342 | Streptococcus salivarius |
| TCMT1345 | Prevotella loescheii |
| TCMT1346 | Helicobacter pylori |
| TCMT1349 | Helicobacter pylori SS1 |
| TCMT1353 | Plasmodium yoelii |
| TCMT1355 | Rhodococcus equi |
| TCMT1356 | Campylobacter coli |
| TCMT1358 | Bacteroides vulgatus |
| TCMT1361 | Neisseria meningitidis |
| TCMT1362 | Bordetella pertussis |
| TCMT1363 | Peptostreptococcus anaerobius |
| TCMT1366 | Prevotella bivia |
| TCMT1371 | Veillonella parvula |
| TCMT1375 | Clostridium tetani |
| TCMT1377 | Staphylococcus lugdunensis |
| TCMT1378 | Acinetobacter haemolyticus |
| TCMT1381 | Listeria innocua |
| TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
| TCMT1383 | Streptomyces griseus |
| TCMT1388 | Prevotella disiens |
| TCMT1389 | Klebsiella oxytoca |
| TCMT1393 | Vibrio sp. |
| TCMT1394 | Mycobacterium aurum |
| TCMT1395 | Staphylococcus sp. |
| TCMT1396 | Fusobacterium |
| TCMT1399 | Chlamydophila pneumoniae |
| TCMT1400 | Mycobacterium mageritense |
| TCMT1401 | Staphylococcus warneri |
| TCMT1402 | Staphylococcus cohnii |
| TCMT1403 | Streptococcus constellatus |
| TCMT1404 | Streptococcus intermedius |
| TCMT1406 | Mycobacterium leprae |
| TCMT1407 | Aeromonas punctata |
| TCMT1408 | Colletotrichum gloeosporioides |
| TCMT1409 | Escherichia coli O157:H7 |
| TCMT1410 | Listeria monocytogenes |
| TCMT1411 | Vibrio parahaemolyticus |
| TCMT1412 | Salmonella typhimurium |
| TCMT1413 | Vibrio splendidus |
| TCMT1414 | Vibrio vulnificus |
| TCMT1415 | Vibrio fluvialis |
| TCMT1416 | Plesiomonas shigelloides |
| TCMT1417 | Aeromonas sobria |
| TCMT1418 | Enterobacteriaceae |
| TCMT1420 | Klebsiella pneumoniae subsp. ozaenae |
| TCMT1421 | Vibrio mimicus |
| TCMT1422 | Clostridium histolyticum |
| TCMT1423 | Peptostreptococcus |
| TCMT1424 | Haemophilus ducreyi |
| TCMT1425 | Moraxella bovis |
| TCMT1427 | Proteus inconstans |
| TCMT1429 | Acinetobacter pittii |
| TCMT1431 | Coxiella burnetii |
| TCMT1432 | Serratia sp. |
| TCMT1434 | Plesiomonas |
| TCMT1435 | Corynebacterium |
| TCMT1438 | Plasmodium falciparum |
| TCMT1439 | Mycobacterium smegmatis |
| TCMT1442 | Leishmania donovani |
| TCMT1443 | Leishmania amazonensis |
| TCMT1447 | Respiratory syncytial virus |
| TCMT1448 | Enterobacter aerogenes |
| TCMT1450 | Plasmodium falciparum 3D7 |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1460 | Mycobacterium intracellulare |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples