TCM Prescription: Yu Lian Tablets



Prescription Description
Prescription IDTCMFx6333
Pinyin NameYu Lian Pian
Chinese Name萸连片
English NameYu Lian Tablets
Function Description胃脘痛, 胁痛, 腹泻
IndicationsHypochondrium pain disorder, Stomach ache disorder, Diarrhea
Disease ICD-11 Category SA00 [Hypochondrium pain disorder (TM1), 胁痛 (TM1) ];
SA51 [Stomach ache disorder (TM1), 胃脘痛 (TM1) ];
ME05.1 [Diarrhoea, 腹泻 ];
Human Tissues Associated with IndicationIntestine, Stomach
ReferenceCFDA
Reference Book/linkhttp://samr.cfda.gov.cn/WS01/CL0001/
Prescription Components
Component ID Latin Name Chinese Name Component Quantity Barcode
TCMH972 Coptis chinensis 黄连 TCMH972 ITSAO4469-14
TCMH2216 Evodia rutaecarpa 吴茱萸 TCMH2216
TCMH1533 Saussurea lappa 木香 TCMH1533
Reference: CFDA

Targeted Human Proteins by the Ingredients of Prescription

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT313 HTR2B Serotonin 2b (5-HT2b) receptor GPCR P41595
TCMT314 HTR2C Serotonin 2c (5-HT2c) receptor GPCR P28335
TCMT315 HTR6 Serotonin 6 (5-HT6) receptor GPCR P50406
TCMT316 MTNR1A Melatonin receptor 1A GPCR P48039
TCMT317 MTNR1B Melatonin receptor 1B GPCR P49286
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT37 HTR2A Serotonin 2a (5-HT2a) receptor GPCR P28223
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT609 CTSL Cathepsin L Unclassified P07711


Targeted Pathogenic Microbes by the Ingredients of Prescription

Target ID Target Name
TCMT1218 Staphylococcus aureus
TCMT1219 Enterococcus
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1230 Human herpesvirus 5
TCMT1232 Pseudomonas aeruginosa
TCMT1236 Mycobacterium bovis
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1255 Human immunodeficiency virus 1
TCMT1289 Shigella dysenteriae
TCMT1305 Salmonella enteritidis
TCMT1318 Human T-lymphotropic virus 1
TCMT1346 Helicobacter pylori
TCMT1353 Plasmodium yoelii
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1385 Candida shehatae
TCMT1438 Plasmodium falciparum
TCMT1439 Mycobacterium smegmatis
TCMT1442 Leishmania donovani
TCMT1454 Bacillus subtilis
TCMT1458 Filobasidiella neoformans
TCMT1460 Mycobacterium intracellulare
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Gene Ontology Associated to Targeted Human Proteins

GO Term GO Name Enriched Genes Log10 Adjusted P-value


KEGG Pathways Associated to Targeted Human Proteins

KEGG Pathway ID Enriched Genes Log10 Adjusted P-value


Target Exprsssion in Healthy Human Tissues (protein & mRNA level)

Protein expression data was from the "Human Proteome Map" dataset
mRNA expression data was from the "GTEx" dataset



Average Target Expression (Fold Change) in Multiple Disease Conditions

Fold Change with Corresponding Normal Samples
Click each cell within the heatmap to access gene expression of individual patient samples
Data Section
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1. General Information of Prescription  
2. Putative Targets  
3. Activity & References for Filtering Putative Targets  
4. GO & Pathway