Prescription Description
| Prescription ID | TCMFx5804 |
| Pinyin Name | Si Fang Wei Pian |
| Chinese Name | 四方胃片 |
| English Name | Si Fang Wei Tablets |
| Function Description | 胃脘痛 |
| Indications | Stomach ache disorder |
| Disease ICD-11 Category |
SA51 [Stomach ache disorder (TM1), 胃脘痛 (TM1)
]; |
| Human Tissues Associated with Indication | Intestine, Stomach |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH789 | Lonicera japonica | 海螵蛸 | TCMH789 | ITSAI3881-14 |
| TCMH249 | Aquilaria agallocha | 沉香 | TCMH249 | KU879012 |
| TCMH972 | Coptis chinensis | 黄连 | TCMH972 | ITSAO4469-14 |
| TCMH284 | Melia toosendan | å·æ¥å | TCMH284 | KY197925 |
| TCMH1219 | Semen armeniacae amarum | 苦æä» | TCMH1219 | |
| TCMH2596 | Fritillaria verticillata | æµ™è´æ¯ | TCMH2596 | |
| TCMH1952 | NA | 柿霜 | TCMH1952 | |
| TCMH2376 | Corydalis yanhusuo | 延胡索 | TCMH2376 | |
| TCMH2216 | Evodia rutaecarpa | å´èŒ±è¸ | TCMH2216 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT160 | HTR7 | Serotonin 7 (5-HT7) receptor | GPCR | P34969 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT27 | DRD1 | Dopamine D1 receptor | GPCR | P21728 |
| TCMT296 | ADORA1 | Adenosine A1 receptor | GPCR | P30542 |
| TCMT313 | HTR2B | Serotonin 2b (5-HT2b) receptor | GPCR | P41595 |
| TCMT314 | HTR2C | Serotonin 2c (5-HT2c) receptor | GPCR | P28335 |
| TCMT315 | HTR6 | Serotonin 6 (5-HT6) receptor | GPCR | P50406 |
| TCMT316 | MTNR1A | Melatonin receptor 1A | GPCR | P48039 |
| TCMT317 | MTNR1B | Melatonin receptor 1B | GPCR | P49286 |
| TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
| TCMT34 | CYP2D6 | Cytochrome P450 2D6 | Oxidoreductase | P10635 |
| TCMT36 | HTR1A | Serotonin 1a (5-HT1a) receptor | GPCR | P08908 |
| TCMT37 | HTR2A | Serotonin 2a (5-HT2a) receptor | GPCR | P28223 |
| TCMT38 | DRD2 | Dopamine D2 receptor | GPCR | P14416 |
| TCMT46 | F3 | Coagulation factor III | Unclassified | P13726 |
| TCMT597 | SLC28A3 | Solute carrier family 28 member 3 | Transporter | Q9HAS3 |
| TCMT609 | CTSL | Cathepsin L | Unclassified | P07711 |
| TCMT615 | SENP8 | Sentrin-specific protease 8 | Protease | Q96LD8 |
| TCMT616 | SENP7 | Sentrin-specific protease 7 | Protease | Q9BQF6 |
| TCMT643 | ADRA1A | Alpha-1a adrenergic receptor | GPCR | P35348 |
| TCMT646 | HTR5A | Serotonin 5a (5-HT5a) receptor | GPCR | P47898 |
| TCMT651 | DRD3 | Dopamine D3 receptor | GPCR | P35462 |
| TCMT709 | SLC28A2 | Sodium/nucleoside cotransporter 2 | Transporter | O43868 |
| TCMT710 | SLC28A1 | Sodium/nucleoside cotransporter 1 | Transporter | O00337 |
| TCMT853 | SIGMAR1 | Sigma opioid receptor | Unclassified | Q99720 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1214 | Enterococcus faecium |
| TCMT1218 | Staphylococcus aureus |
| TCMT1223 | Staphylococcus epidermidis |
| TCMT1226 | Klebsiella pneumoniae |
| TCMT1230 | Human herpesvirus 5 |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1236 | Mycobacterium bovis |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1253 | Penicillium chrysogenum |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1289 | Shigella dysenteriae |
| TCMT1305 | Salmonella enteritidis |
| TCMT1310 | Enterococcus hirae |
| TCMT1318 | Human T-lymphotropic virus 1 |
| TCMT1346 | Helicobacter pylori |
| TCMT1353 | Plasmodium yoelii |
| TCMT1355 | Rhodococcus equi |
| TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
| TCMT1385 | Candida shehatae |
| TCMT1438 | Plasmodium falciparum |
| TCMT1439 | Mycobacterium smegmatis |
| TCMT1442 | Leishmania donovani |
| TCMT1454 | Bacillus subtilis |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1460 | Mycobacterium intracellulare |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
| TCMT1464 | Hepatitis B virus |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples