Prescription Description
| Prescription ID | TCMFx5396 |
| Pinyin Name | Tian Huang Hou Zao San |
| Chinese Name | 天黄猴枣散 |
| English Name | Tian Huang Hou Zao Powder |
| Function Description | 咳嗽, ä¸å¯ |
| Indications | Insomnia disorder, Insomnia |
| Disease ICD-11 Category |
SD84 [Insomnia disorder (TM1), ä¸å¯ (TM1)
]; 7A0Z [Insomnia disorders, unspecified, å¤±çœ éšœç¢ï¼Œæœªç‰¹æŒ‡çš„ ]; |
| Human Tissues Associated with Indication | Lung, Heart |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH898 | Rhesus macaque | 猴枣 | TCMH898 | |
| TCMH404 | Rhizoma arisaema cum bile | 胆å—星 | TCMH404 | |
| TCMH1060 | Bombyx batryticatus | 僵蚕 | TCMH1060 | |
| TCMH183 | Dryobalanops aromatica | 冰片 | TCMH183 | GBVK4926-11 |
| TCMH189 | Mentholum | è–„è·è„‘ | TCMH189 | |
| TCMH1573 | Bovis calculus | 牛黄 | TCMH1573 | |
| TCMH2102 | Concretio silicea bambusae | 天竺黄 | TCMH2102 | |
| TCMH2090 | Gastrodia elata | 天麻 | TCMH2090 | |
| TCMH2605 | Margarita | çç | TCMH2605 | |
| TCMH1709 | Buthus martensi | å…¨èŽ | TCMH1709 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT296 | ADORA1 | Adenosine A1 receptor | GPCR | P30542 |
| TCMT297 | FABP4 | Fatty acid binding protein adipocyte | Unclassified | P15090 |
| TCMT44 | GLO1 | Glyoxalase I | Lyase | Q04760 |
| TCMT558 | TOP2A | DNA topoisomerase II alpha | Isomerase | P11388 |
| TCMT597 | SLC28A3 | Solute carrier family 28 member 3 | Transporter | Q9HAS3 |
| TCMT614 | EGLN1 | Egl nine homolog 1 | Oxidoreductase | Q9GZT9 |
| TCMT709 | SLC28A2 | Sodium/nucleoside cotransporter 2 | Transporter | O43868 |
| TCMT710 | SLC28A1 | Sodium/nucleoside cotransporter 1 | Transporter | O00337 |
| TCMT737 | APOBEC3G | DNA dC->dU-editing enzyme APOBEC-3G | Unclassified | Q9HC16 |
| TCMT740 | PIK3CG | PI3-kinase p110-gamma subunit | Transferase | P48736 |
| TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
| TCMT808 | FABP5 | Fatty acid binding protein epidermal | Unclassified | Q01469 |
| TCMT809 | FABP2 | Fatty acid binding protein intestinal | Unclassified | P12104 |
| TCMT810 | TLR2 | Toll-like receptor 2 | Unclassified | O60603 |
| TCMT907 | FDPS | Farnesyl diphosphate synthase | Lyase | P14324 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1178 | Actinomyces viscosus |
| TCMT1218 | Staphylococcus aureus |
| TCMT1223 | Staphylococcus epidermidis |
| TCMT1229 | Enterococcus faecalis |
| TCMT1245 | Phytophthora cactorum |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1253 | Penicillium chrysogenum |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1361 | Neisseria meningitidis |
| TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
| TCMT1408 | Colletotrichum gloeosporioides |
| TCMT1412 | Salmonella typhimurium |
| TCMT1438 | Plasmodium falciparum |
| TCMT1442 | Leishmania donovani |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1462 | Streptococcus mutans |
| TCMT1464 | Hepatitis B virus |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples