Prescription Description
| Prescription ID | TCMFx5175 |
| Pinyin Name | Shi Jun Zi Wan |
| Chinese Name | 使君子丸 |
| English Name | Shi Jun Zi Pills |
| Function Description | 疳病, 虫积 |
| Indications | Infantile malnutrition disorder |
| Disease ICD-11 Category |
SE37 [Infantile malnutrition disorder (TM1), 疳病 (TM1)
]; |
| Human Tissues Associated with Indication | Spleen, Stomach |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1938 | Quisqualis indica | 使君子 | TCMH1938 | GENG1719-16 |
| TCMH2094 | Arisaema consanguineum | 天南星 | TCMH2094 | GBVY604-14 |
| TCMH182 | Areca catechu | 槟榔 | TCMH182 | ITSAA732-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT23 | ALPL | Alkaline phosphatase, tissue-nonspecific isozyme | Hydrolase | P05186 |
| TCMT289 | TBXAS1 | Thromboxane-A synthase | Isomerase | P24557 |
| TCMT292 | CHRM1 | Muscarinic acetylcholine receptor M1 | GPCR | P11229 |
| TCMT293 | CHRM2 | Muscarinic acetylcholine receptor M2 | GPCR | P08172 |
| TCMT551 | CHRM4 | Muscarinic acetylcholine receptor M4 | GPCR | P08173 |
| TCMT661 | FOLH1 | Glutamate carboxypeptidase II | Hydrolase | Q04609 |
| TCMT822 | FUT7 | Alpha-(1,3)-fucosyltransferase 7 | Transferase | Q11130 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1175 | Human immunodeficiency virus |
| TCMT1178 | Actinomyces viscosus |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1212 | Verticillium dahliae |
| TCMT1218 | Staphylococcus aureus |
| TCMT1222 | Plasmodium falciparum D6 |
| TCMT1226 | Klebsiella pneumoniae |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1438 | Plasmodium falciparum |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1462 | Streptococcus mutans |
| TCMT1464 | Hepatitis B virus |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples