Prescription Description
| Prescription ID | TCMFx5106 |
| Pinyin Name | San Qi Xue Shang Ning Jiao Nang |
| Chinese Name | 三七血伤宁胶囊 |
| English Name | San Qi Xue Shang Ning Capsules |
| Function Description | 血证, 吐血, 咯血, 便血, 月经失调, 痛经, 闭经, 月经过多, 恶露不绝, 胃脘痛, 胁痛 |
| Indications | Hypochondrium pain disorder, Stomach ache disorder, Menorrhagia disorder, Amenorrhea disorder, Dysmenorrhea disorder, Postpartum lochiorrhea disorder, Tracheobronchial hemorrhage, Duodenal ulcer with hemorrhage, Hematuria |
| Disease ICD-11 Category |
SA00 [Hypochondrium pain disorder (TM1), 胁痛 (TM1)
]; SA51 [Stomach ache disorder (TM1), 胃脘痛 (TM1) ]; SB90 [Menorrhagia disorder (TM1), 月经过多 (TM1) ]; SB94 [Amenorrhea disorder (TM1), 闭经 (TM1) ]; SB96 [Dysmenorrhea disorder (TM1), 痛经 (TM1) ]; SC13 [Postpartum lochiorrhea disorder (TM1), 恶露不绝 (TM1) ]; MD23 [Haemorrhage from other sites in respiratory passages, 呼吸道其他部位出血 ]; DA63.Z [Duodenal ulcer, unspecified, 十二指肠溃疡，未特指的 ]; MF50.4 [Haematuria, 血尿 ]; |
| Human Tissues Associated with Indication | Uterus, Stomach |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1768 | Panax notoginseng | 三七 | TCMH1768 | ITSAO2360-14 |
| TCMH2646 | Rhizoma paridis | 重楼 | TCMH2646 | |
| TCMH222 | Aconitum carmichaelii | 草乌 | TCMH222 | ITSAH2410-14 |
| TCMH2732 | Callicarpae formosanae folium | 紫珠叶 | TCMH2732 | |
| TCMH1845 | Dioscorea batatas | 山药 | TCMH1845 | |
| TCMH851 | Veratrum japonicum | 黑紫藜芦 | TCMH851 | ITSAB1102-14 |
| TCMH183 | Dryobalanops aromatica | 冰片 | TCMH183 | GBVK4926-11 |
| TCMH2682 | Cinnabaris | 朱砂 | TCMH2682 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT289 | TBXAS1 | Thromboxane-A synthase | Isomerase | P24557 |
| TCMT636 | POLA1 | DNA polymerase alpha subunit | Transferase | P09884 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1218 | Staphylococcus aureus |
| TCMT1229 | Enterococcus faecalis |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1243 | Aspergillus flavus |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1438 | Plasmodium falciparum |
| TCMT1454 | Bacillus subtilis |
| TCMT1458 | Filobasidiella neoformans |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples