Prescription Description
| Prescription ID | TCMFx4530 |
| Pinyin Name | Liu Shen Wan |
| Chinese Name | 六神丸 |
| English Name | Liu Shen Pills |
| Function Description | 烂喉丹痧, 喉痹, 喉痈, 乳蛾, 痈疡, 疔疮, 乳痈, 发背, 无名肿毒 |
| Indications | Tonsillitis disorder, Pharyngitis, Scarlet fever, Tonsillitis |
| Disease ICD-11 Category |
SC93 [Tonsillitis disorder (TM1), 乳蛾 (TM1)
]; CA0Z [Upper respiratory tract disorders, unspecified, 上呼吸道疾患，未特指的 ]; 1B50 [Scarlet fever, 猩红热 ]; |
| Human Tissues Associated with Indication | Lung |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH2605 | Margarita | 珍珠 | TCMH2605 | |
| TCMH1573 | Bovis calculus | 牛黄 | TCMH1573 | |
| TCMH1880 | Moschus moschiferus | 麝香 | TCMH1880 | GBMA2112-09 |
| TCMH2329 | Realgar | 雄黄 | TCMH2329 | |
| TCMH233 | Bufonis venenum | 蟾酥 | TCMH233 | |
| TCMH183 | Dryobalanops aromatica | 冰片 | TCMH183 | GBVK4926-11 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT187 | AR | Androgen Receptor | Nuclear receptor | P10275 |
| TCMT203 | G6PD | Glucose-6-phosphate 1-dehydrogenase | Oxidoreductase | P11413 |
| TCMT230 | HSD17B3 | Estradiol 17-beta-dehydrogenase 3 | Oxidoreductase | P37058 |
| TCMT236 | ESR2 | Estrogen receptor beta | Nuclear receptor | Q92731 |
| TCMT261 | DAPK1 | Death-associated protein kinase 1 | Kinase | P53355 |
| TCMT344 | AOX1 | Aldehyde oxidase | Oxidoreductase | Q06278 |
| TCMT591 | ESRRA | Estrogen-related receptor alpha | Nuclear receptor | P11474 |
| TCMT807 | SLC22A12 | Solute carrier family 22 member 12 | Transporter | Q96S37 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
| TCMT907 | FDPS | Farnesyl diphosphate synthase | Lyase | P14324 |
| TCMT910 | ESRRB | Estrogen-related receptor beta | Nuclear receptor | O95718 |
| TCMT974 | GPER1 | G-protein coupled estrogen receptor 1 | GPCR | Q99527 |
| TCMT99 | SHBG | Testis-specific androgen-binding protein | Unclassified | P04278 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1229 | Enterococcus faecalis |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1438 | Plasmodium falciparum |
| TCMT1442 | Leishmania donovani |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples