Prescription Description
| Prescription ID | TCMFx3998 |
| Pinyin Name | Jian Er San |
| Chinese Name | 健儿散 |
| English Name | Jian Er Powder |
| Function Description | 厌食, 积滞 |
| Indications | Dyspepsia, Anorexia |
| Disease ICD-11 Category |
MD92 [Dyspepsia, 消化不良
]; MG43.7 [Anorexia, 纳差 ]; |
| Human Tissues Associated with Indication | Spleen, Intestine, Stomach |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1845 | Dioscorea batatas | 山药 | TCMH1845 | |
| TCMH286 | Chuanminshen violaceum | 川明参 | TCMH286 | ITSAI1328-14 |
| TCMH2486 | Coix lacryma- jobi var. ma - yuen | 薏苡仁 | TCMH2486 | |
| TCMH1430 | Hordeum vulgare | 麦芽 | TCMH1430 | ITSAI3101-14 |
| TCMH436 | Fructus oryzae germinatus | 稻芽 | TCMH436 | |
| TCMH1026 | Gallus gallus domesticus | 鸡内金 | TCMH1026 | ACLB009-06 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT161 | HCAR2 | Hydroxycarboxylic acid receptor 2 | GPCR | Q8TDS4 |
| TCMT30 | PTGS2 | Cyclooxygenase-2 | Oxidoreductase | P35354 |
| TCMT315 | HTR6 | Serotonin 6 (5-HT6) receptor | GPCR | P50406 |
| TCMT335 | MPO | Myeloperoxidase | Oxidoreductase | P05164 |
| TCMT336 | IDO1 | Indoleamine 2,3-dioxygenase | Oxidoreductase | P14902 |
| TCMT63 | PPARA | Peroxisome proliferator-activated receptor alpha | Nuclear receptor | Q07869 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1172 | Staphylococcus aureus subsp. aureus RN4220 |
| TCMT1174 | Mycobacterium bovis BCG |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1177 | Haemophilus influenzae |
| TCMT1179 | Escherichia coli ATCC 8739 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1182 | Streptococcus sanguinis |
| TCMT1184 | Mycobacterium fortuitum |
| TCMT1185 | Mycobacterium phlei |
| TCMT1187 | Enterococcus faecalis ATCC 29212 |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1191 | Bacillus megaterium |
| TCMT1192 | Bacteria |
| TCMT1193 | Staphylococcus |
| TCMT1194 | Shigella sonnei |
| TCMT1196 | Salmonella |
| TCMT1198 | Serratia marcescens |
| TCMT1199 | Streptococcus sp. 'group A' |
| TCMT1200 | Bacillus thuringiensis |
| TCMT1201 | Staphylococcus epidermidis ATCC 12228 |
| TCMT1202 | Mycoplasma hominis |
| TCMT1203 | Mycoplasma pneumoniae |
| TCMT1204 | Clostridium perfringens |
| TCMT1207 | Legionella pneumophila |
| TCMT1208 | Escherichia coli K12 |
| TCMT1209 | Staphylococcus haemolyticus |
| TCMT1211 | Fusobacterium nucleatum |
| TCMT1213 | Neisseria gonorrhoeae |
| TCMT1214 | Enterococcus faecium |
| TCMT1215 | Pseudomonas aeruginosa PAO1 |
| TCMT1216 | Vibrio cholerae |
| TCMT1217 | Bacillus anthracis |
| TCMT1218 | Staphylococcus aureus |
| TCMT1219 | Enterococcus |
| TCMT1220 | Streptococcus pneumoniae R6 |
| TCMT1223 | Staphylococcus epidermidis |
| TCMT1224 | Proteus mirabilis |
| TCMT1226 | Klebsiella pneumoniae |
| TCMT1227 | Streptococcus |
| TCMT1229 | Enterococcus faecalis |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1236 | Mycobacterium bovis |
| TCMT1237 | Mycobacterium kansasii |
| TCMT1243 | Aspergillus flavus |
| TCMT1244 | Staphylococcus saprophyticus |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1252 | Alcaligenes faecalis |
| TCMT1260 | Streptococcus agalactiae |
| TCMT1262 | Mycoplasma putrefaciens |
| TCMT1266 | Mycobacterium abscessus |
| TCMT1267 | Mycobacterium chelonae |
| TCMT1271 | Shigella flexneri |
| TCMT1272 | Campylobacter jejuni |
| TCMT1273 | Pseudomonas putida |
| TCMT1274 | Shigella boydii |
| TCMT1276 | Klebsiella |
| TCMT1277 | Serratia |
| TCMT1278 | Pseudomonas |
| TCMT1281 | Clostridium difficile |
| TCMT1286 | Bacillus cereus |
| TCMT1287 | Bacillus subtilis subsp. spizizenii ATCC 6633 |
| TCMT1289 | Shigella dysenteriae |
| TCMT1290 | Acinetobacter calcoaceticus |
| TCMT1291 | Haemophilus parainfluenzae |
| TCMT1299 | Morganella morganii |
| TCMT1300 | Enterobacter |
| TCMT1301 | Klebsiella sp. |
| TCMT1303 | Bacillus |
| TCMT1304 | Staphylococcus capitis |
| TCMT1305 | Salmonella enteritidis |
| TCMT1307 | Penicillium marneffei |
| TCMT1309 | Aspergillus clavatus |
| TCMT1310 | Enterococcus hirae |
| TCMT1314 | Streptococcus viridans |
| TCMT1315 | Streptococcus sp. |
| TCMT1317 | Staphylococcus lentus |
| TCMT1321 | Staphylococcus hominis |
| TCMT1322 | Streptococcus mitis |
| TCMT1326 | Shigella |
| TCMT1331 | Acinetobacter sp. |
| TCMT1332 | Bacillus licheniformis |
| TCMT1334 | Chlamydia trachomatis |
| TCMT1340 | Staphylococcus faecalis |
| TCMT1341 | Streptococcus oralis |
| TCMT1342 | Streptococcus salivarius |
| TCMT1345 | Prevotella loescheii |
| TCMT1346 | Helicobacter pylori |
| TCMT1353 | Plasmodium yoelii |
| TCMT1355 | Rhodococcus equi |
| TCMT1356 | Campylobacter coli |
| TCMT1358 | Bacteroides vulgatus |
| TCMT1361 | Neisseria meningitidis |
| TCMT1362 | Bordetella pertussis |
| TCMT1363 | Peptostreptococcus anaerobius |
| TCMT1366 | Prevotella bivia |
| TCMT1371 | Veillonella parvula |
| TCMT1375 | Clostridium tetani |
| TCMT1377 | Staphylococcus lugdunensis |
| TCMT1378 | Acinetobacter haemolyticus |
| TCMT1381 | Listeria innocua |
| TCMT1383 | Streptomyces griseus |
| TCMT1388 | Prevotella disiens |
| TCMT1389 | Klebsiella oxytoca |
| TCMT1393 | Vibrio sp. |
| TCMT1394 | Mycobacterium aurum |
| TCMT1395 | Staphylococcus sp. |
| TCMT1396 | Fusobacterium |
| TCMT1399 | Chlamydophila pneumoniae |
| TCMT1400 | Mycobacterium mageritense |
| TCMT1401 | Staphylococcus warneri |
| TCMT1402 | Staphylococcus cohnii |
| TCMT1403 | Streptococcus constellatus |
| TCMT1404 | Streptococcus intermedius |
| TCMT1406 | Mycobacterium leprae |
| TCMT1407 | Aeromonas punctata |
| TCMT1409 | Escherichia coli O157:H7 |
| TCMT1410 | Listeria monocytogenes |
| TCMT1411 | Vibrio parahaemolyticus |
| TCMT1412 | Salmonella typhimurium |
| TCMT1413 | Vibrio splendidus |
| TCMT1414 | Vibrio vulnificus |
| TCMT1415 | Vibrio fluvialis |
| TCMT1416 | Plesiomonas shigelloides |
| TCMT1417 | Aeromonas sobria |
| TCMT1418 | Enterobacteriaceae |
| TCMT1420 | Klebsiella pneumoniae subsp. ozaenae |
| TCMT1421 | Vibrio mimicus |
| TCMT1422 | Clostridium histolyticum |
| TCMT1423 | Peptostreptococcus |
| TCMT1424 | Haemophilus ducreyi |
| TCMT1425 | Moraxella bovis |
| TCMT1427 | Proteus inconstans |
| TCMT1429 | Acinetobacter pittii |
| TCMT1431 | Coxiella burnetii |
| TCMT1432 | Serratia sp. |
| TCMT1434 | Plesiomonas |
| TCMT1435 | Corynebacterium |
| TCMT1438 | Plasmodium falciparum |
| TCMT1439 | Mycobacterium smegmatis |
| TCMT1448 | Enterobacter aerogenes |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1460 | Mycobacterium intracellulare |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples