TCM Prescription: Gu Zhi Ning Cha Ji



Prescription Description
Prescription IDTCMFx3579
Pinyin NameGu Zhi Ning Cha Ji
Chinese Name骨质宁搽剂
English NameGu Zhi Ning Cha Ji
Function Description跌打损伤, 痹病
IndicationsArthritis
Disease ICD-11 Category FA2Z [Inflammatory arthropathies, unspecified, 炎性关节病,未特指的 ];
Human Tissues Associated with IndicationSkeletalMuscle, Blood
ReferenceCFDA
Reference Book/linkhttp://samr.cfda.gov.cn/WS01/CL0001/
Prescription Components
Component ID Latin Name Chinese Name Component Quantity Barcode
TCMH2561 NA 云母石 TCMH2561
TCMH972 Coptis chinensis 黄连 TCMH972 ITSAO4469-14
TCMH54 Alumen 白矾 TCMH54
Reference: CFDA

Targeted Human Proteins by the Ingredients of Prescription

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT46 F3 Coagulation factor III Unclassified P13726


Targeted Pathogenic Microbes by the Ingredients of Prescription

Target ID Target Name
TCMT1218 Staphylococcus aureus
TCMT1226 Klebsiella pneumoniae
TCMT1230 Human herpesvirus 5
TCMT1232 Pseudomonas aeruginosa
TCMT1236 Mycobacterium bovis
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1255 Human immunodeficiency virus 1
TCMT1289 Shigella dysenteriae
TCMT1305 Salmonella enteritidis
TCMT1318 Human T-lymphotropic virus 1
TCMT1346 Helicobacter pylori
TCMT1353 Plasmodium yoelii
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1385 Candida shehatae
TCMT1438 Plasmodium falciparum
TCMT1439 Mycobacterium smegmatis
TCMT1442 Leishmania donovani
TCMT1454 Bacillus subtilis
TCMT1458 Filobasidiella neoformans
TCMT1460 Mycobacterium intracellulare
TCMT1462 Streptococcus mutans
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Gene Ontology Associated to Targeted Human Proteins

GO Term GO Name Enriched Genes Log10 Adjusted P-value


KEGG Pathways Associated to Targeted Human Proteins

KEGG Pathway ID Enriched Genes Log10 Adjusted P-value


Target Exprsssion in Healthy Human Tissues (protein & mRNA level)

Protein expression data was from the "Human Proteome Map" dataset
mRNA expression data was from the "GTEx" dataset



Average Target Expression (Fold Change) in Multiple Disease Conditions

Fold Change with Corresponding Normal Samples
Click each cell within the heatmap to access gene expression of individual patient samples
Data Section
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1. General Information of Prescription  
2. Putative Targets  
3. Activity & References for Filtering Putative Targets  
4. GO & Pathway