Prescription Description
| Prescription ID | TCMFx3013 |
| Pinyin Name | Bai Jin Wan |
| Chinese Name | 白金丸 |
| English Name | Bai Jin Pills |
| Function Description | 癫痫 |
| Indications | Epilepsy |
| Disease ICD-11 Category |
8A6Z [Epilepsy or seizures, unspecified, 癫痫或癫痫å‘作，未特指的
]; |
| Human Tissues Associated with Indication | Uterus |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH54 | Alumen | 白矾 | TCMH54 | |
| TCMH2532 | Curcuma aromatica | éƒé‡‘ | TCMH2532 | ITSAF2298-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT187 | AR | Androgen Receptor | Nuclear receptor | P10275 |
| TCMT193 | RELA | Nuclear factor NF-kappa-B p65 subunit | Transcription factor | Q04206 |
| TCMT194 | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7 | Kinase | O43318 |
| TCMT195 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | Kinase | Q02750 |
| TCMT196 | MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 | Kinase | O14733 |
| TCMT208 | MAOA | Monoamine oxidase A | Oxidoreductase | P21397 |
| TCMT230 | HSD17B3 | Estradiol 17-beta-dehydrogenase 3 | Oxidoreductase | P37058 |
| TCMT301 | PTGES | Prostaglandin E synthase | Isomerase | O14684 |
| TCMT45 | APP | Beta amyloid A4 protein | Unclassified | P05067 |
| TCMT46 | F3 | Coagulation factor III | Unclassified | P13726 |
| TCMT565 | EP300 | Histone acetyltransferase p300 | Transferase | Q09472 |
| TCMT566 | NOS2 | Nitric oxide synthase, inducible | Oxidoreductase | P35228 |
| TCMT570 | ANPEP | Aminopeptidase N | Unclassified | P15144 |
| TCMT725 | CACNA1C | Voltage-gated L-type calcium channel alpha-1C subunit | Ion channel | Q13936 |
| TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
| TCMT87 | CYP2C9 | Cytochrome P450 2C9 | Oxidoreductase | P11712 |
| TCMT99 | SHBG | Testis-specific androgen-binding protein | Unclassified | P04278 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1215 | Pseudomonas aeruginosa PAO1 |
| TCMT1221 | Human herpesvirus 4 |
| TCMT1224 | Proteus mirabilis |
| TCMT1226 | Klebsiella pneumoniae |
| TCMT1246 | Escherichia coli |
| TCMT1249 | Dengue virus 2 |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1313 | Human immunodeficiency virus 2 |
| TCMT1314 | Streptococcus viridans |
| TCMT1346 | Helicobacter pylori |
| TCMT1438 | Plasmodium falciparum |
| TCMT1454 | Bacillus subtilis |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples