| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, HMGCR, HSD11B2, HSD17B2, IGF1R, INSR, MMP2, MMP9, PIK3CA, PPARA, PTGS2, RORC, SRC, TEK, TYR |
13.9838 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
13.7186 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MMP2, PIK3CA, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
12.9189 |
|
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CA12, CA2, CA7, CDK6, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
12.5019 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD2, EGFR, ESR1, FABP3, FABP4, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2 |
12.1834 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
12.1305 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
12.1207 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
11.6851 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PIM1, PTGS1, PTGS2, SMAD3, SRC, TEK, XDH |
11.4479 |
|
[BP] GO:0042221 |
response to chemical
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, PIK3CA, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
10.9569 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FLT3, HSD11B2, PTGS2, RORC, SRC, TEK, TYR |
10.7623 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP2, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
10.6923 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
10.1883 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, XDH |
9.8721 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, XDH |
9.8721 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.64114 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.47599 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MMP9, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A, XDH |
9.20999 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CDK6, DRD1, DRD2, DRD3, EGFR, HCAR2, HMGCR, KDR, PIK3CB, PTGS2, SRC, TNKS, TNKS2 |
9.18814 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, F3, FLT3, GPR35, HMGCR, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.18293 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DRD1, DRD5, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
9.16692 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, ESR1, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
8.92152 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AXL, BCL2, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESRRB, F3, FABP4, HMGCR, HSD11B2, HSD17B2, HTR1A, IGF1R, INSR, MET, MMP1, MMP12, MMP2, MMP9, PIK3CA, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TYR |
8.72218 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD17B2, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TOP2A, TYR |
8.44667 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, DRD3, EGFR, ESR1, F3, FLT3, HMGCR, HTR1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, PIM1, PTGS2, TEK |
8.3818 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
8.29249 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, PTGS2, RORC, SRC, TYR |
8.22158 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, F3, FLT3, GPR35, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
8.16003 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALPI, ALPL, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
8.11361 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, INSR, PPARA, PTGS2, SRC, TEK |
7.99703 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
7.99138 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
7.97995 |
|
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, F3, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B2, HSPA1A, HTR1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, TYR |
7.91685 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.88327 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, ALPI, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD2, EGFR, FABP3, FABP4, FUT7, GBA2, HMGCR, MET, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2 |
7.7825 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2D6, TYR |
7.7825 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.7748 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESRRA, F3, FABP4, FLT3, GPR35, HMGCR, HSPA1A, INSR, KDR, MET, MMP12, MMP2, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.77464 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AXL, BCL2, CYP1B1, DRD2, EGFR, F3, FLT3, GPR35, HMGCR, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
7.72324 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
7.72324 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALPI, ALPL, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PTGS2, PTPN1, SRC, TEK, TNKS, XDH |
7.72324 |
|
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, APEX1, AXL, BCL2, CA2, CA7, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F3, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.69033 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPI, ALPL, AOX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
7.6815 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
7.63646 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, DRD3, EGFR, F3, INSR, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
7.56516 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX5, AOX1, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, PIK3CA, PIM1, PPARA, PTGS1, PTGS2, TYR, XDH |
7.42953 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
7.39459 |
|
[BP] GO:0042493 |
response to drug
|
AKR1B1, APEX1, AXL, BCL2, CA9, CDK6, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, HMGCR, HSD11B2, KDR, PTGS2, SRC |
7.34636 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD5, EGFR, ESR1, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, PIK3CA, PTGS2, RORC, SMAD3, SRC |
7.33387 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, HMGCR, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.33173 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
7.32283 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, DRD1, DRD2, DRD3, EGFR, HCAR2, PIK3CB, PTGS2, TNKS, TNKS2 |
7.27312 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, HMGCR, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.27269 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
7.16875 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, IGF1R, KDR, MMP9, PIK3CA, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.16875 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, DRD2, EGFR, ESR1, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A |
7.08769 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
7.05845 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, PIK3CA, PPARA, SMAD3, SRC, TEK, TYR |
7.05474 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
7.04706 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ESRRB, FABP3, FLT3, HMGCR, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.88407 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ESRRB, FABP3, FLT3, HMGCR, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.88407 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
6.87512 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DRD1, DRD5, EGFR, ESR1, FABP4, FLT3, IGF1R, INSR, KDR, MMP2, PIK3CA, PTGS2, RORC, SMAD3, SRC |
6.87396 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TYR, XDH |
6.87028 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, AURKB, BCL2, CDC25B, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GPR35, HMGCR, HSPA1A, IGF1R, INSR, MET, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
6.81937 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.80345 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F3, FABP4, FLT3, GPR35, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
6.79544 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, APEX1, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, KDR, MMP9, PTGS2, SRC |
6.76195 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, APEX1, AXL, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, FLT3, GPR35, INSR, MET, PIK3CA, PIK3CB, SMAD3, SRC |
6.72726 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
6.7235 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, HMGCR, HSPA1A, IGF1R, INSR, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
6.69692 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, HMGCR, KDR, SRC |
6.58588 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, AURKB, CSNK2A1, CYP1B1, CYP2D6, DRD2, DRD3, DRD5, DUSP3, ESR1, FABP4, GPR35, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC, TNKS |
6.49955 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, BCL2, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, XDH |
6.49955 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, BCL2, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, XDH |
6.47852 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TYR |
6.41165 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALPL, AXL, BCL2, CA2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FLT3, GBA2, HSD11B1, HSD17B2, INSR, KDR, MMP9, PIK3CA, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
6.17454 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, DRD3, EGFR, HMGCR, HSD11B2, HSPA1A, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK, TYR |
6.11427 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F3, FLT3, GPR35, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
6.06214 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, BCL2, CDK6, CYP19A1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.04726 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HCAR2, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
6.01069 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.9802 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD5, EGFR, ESR1, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NUAK1, PIK3CA, PTGS2, PTPN1, RORC, SMAD3, SRC, TOP2A |
5.9802 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TYR |
5.9419 |
|
[BP] GO:0006468 |
protein phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, SRC, TEK, TNKS |
5.85464 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALPI, CSNK2A1, CYP19A1, CYP1A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, PIK3CA, PIK3CB, PTGS1, PTGS2 |
5.82341 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9 |
5.80818 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, GPR35, INSR, MET, PIK3CA, PIK3CB, SMAD3 |
5.80752 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, PIM1, SRC, TEK |
5.7708 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
5.71671 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, DRD5, EGFR, ESR1, IGF1R, INSR, MMP2, MMP9, PIK3CA, PTGS2, RORC, SRC |
5.70429 |
|
[BP] GO:0008217 |
None
|
ADORA1, DRD2, DRD3, DRD5, HSD11B2, PPARA, PTGS1, PTGS2, SMAD3 |
5.66063 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
5.59985 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F3, INSR, MET, PIK3CA, PIK3CB, SRC, TEK |
5.59657 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, GBA2, HMGCR, HTR1A, TYR |
5.56295 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, CDK6, CYP19A1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP2, NUAK1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.54867 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
5.53755 |
|
[BP] GO:0003018 |
None
|
ADORA1, DRD1, DRD5, EGFR, HMGCR, HTR1A, PTGS2, SRC, TEK |
5.53755 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, AURKB, BCL2, CSNK2A1, CYP2D6, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, HCAR2, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, PIK3CA, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
5.53319 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, DRD2, DRD3, EGFR, ESR1, F3, FABP4, HMGCR, KDR, MET, MMP12, PPARA, PTGS2, SMAD3, TEK |
5.4971 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, CYP1A1, CYP1B1, DRD1, DRD5, EGFR, ESR1, FLT3, PTGS2, RORC, SRC |
5.41144 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD2, DRD3, DUSP3, ESR1, HMGCR, HSPA1A, IGF1R, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
5.361 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR1, PPARA, RORC, SRC, TOP2A |
5.361 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP4, FLT3, HMGCR, IGF1R, INSR, KDR, MMP9, PIK3CA, PIK3CB, PPARA, PTGS2, PTPN1, SRC, TEK, XDH |
5.34885 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HCAR2, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
5.3433 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, DRD3, FABP3, FLT3, HCAR2, HMGCR, PPARA, PTGS2, RORC, SRC, TEK |
5.2714 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
BCL2, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
5.2714 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
5.27009 |
|
[BP] GO:0016310 |
phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TNKS |
5.2494 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD1, DRD2, DRD3, HTR1A, TYR |
5.2494 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
BCL2, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
5.10754 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
5.08492 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, BCL2, CYP1A1, DRD2, DRD5, EGFR, PPARA, SMAD3 |
5.05762 |
|
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, AXL, BCL2, CA2, CA7, CYP19A1, DRD1, DRD2, DRD3, EGFR, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, INSR, MMP12, MMP9, PIK3CB, PPARA, PTGS2, PTPN1, SMAD3, SRC |
4.99477 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
BCL2, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
4.99477 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, TNKS, TOP2A |
4.95731 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.94542 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD5, EGFR, HSD11B2, HSPA1A, HTR1A, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TOP2A |
4.91726 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.89178 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, BCL2, CDC25B, DRD2, EGFR, ESRRB, FLT3, HMGCR, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
4.87459 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS1, PTGS2 |
4.87459 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK |
4.85264 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
BCL2, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
4.85264 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD2, DRD3, EGFR, HTR1A, INSR, PTGS2, SMAD3 |
4.85264 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, HMGCR, IGF1R, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
4.74036 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, GPR35, HCAR2, HMGCR, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PIK3CA, PIM1, PTGS2, SMAD3, SRC, TEK, TNKS2, XDH |
4.71057 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS1, PTGS2 |
4.68067 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, AXL, BCL2, CA1, CA2, CDK6, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, IGF1R, INSR, KDR, MET, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.67226 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
4.67152 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, PTGS1, PTGS2, SRC |
4.65496 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, KDR, MET, MMP12, PPARA, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
4.65096 |
|
[BP] GO:0003013 |
None
|
ADORA1, DRD1, DRD5, EGFR, HMGCR, HTR1A, PTGS2, SRC, TEK |
4.64075 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.59879 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, DRD1, DRD2, DRD3, KDR, SRC |
4.59499 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, PTGS2, SMAD3, SRC, TNKS, TOP2A |
4.56489 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
4.53271 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, EGFR, HSPA1A |
4.51239 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS1, PTGS2 |
4.50894 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, KDR, PTGS2, SRC |
4.50279 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, DRD1, DRD2, DRD5, PTGS2 |
4.49545 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, BCL2, CDC25B, DRD2, EGFR, FLT3, HMGCR, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
4.48282 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.47657 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, IGF1R, INSR, MET, MMP12, PPARA, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
4.44664 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
4.4162 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, SRC |
4.4162 |
|
[BP] GO:0001963 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.36865 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ESR1, ESR2, F3, FLT3, HSPA1A, INSR, MET, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
4.35604 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GLO1, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
4.29968 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, BCL2, CDC25B, CSNK2A1, DRD2, EGFR, ESR1, F3, FLT3, HMGCR, HSPA1A, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.29574 |
|
[BP] GO:0008283 |
cell proliferation
|
ACHE, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, HTR1A, MET, PIK3CB, PIM1, SRC, TEK, TYR |
4.29123 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, PTGS2 |
4.28072 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, PTGS2 |
4.28072 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2D6, NQO2, PTGS1, RORC |
4.27919 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, DRD1, DRD5, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, INSR, MMP2, MMP9, PTGS2, SRC, TOP2A |
4.27696 |
|
[BP] GO:0032225 |
None
|
DRD1, DRD2, DRD3, PTGS2 |
4.26818 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
4.26701 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, MET, MMP12, PPARA, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
4.2308 |
|
[BP] GO:0097756 |
None
|
ADORA1, DRD5, HMGCR, HTR1A, PTGS2 |
4.21334 |
|
[BP] GO:0050801 |
ion homeostasis
|
BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, GPR35, PIK3CB, SMAD3 |
4.19815 |
|
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ACHE, AKR1B1, AKR1B10, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
4.18453 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC |
4.17671 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PIM1, PPARA, RORC, SRC |
4.1611 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, CA2, CA7, DRD1, DRD2, EGFR, PTGS2 |
4.13188 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, HMGCR, IGF1R, INSR, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
4.12014 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, DRD2, EGFR, ESR1, FABP4, HSPA1A, MMP12, MMP2, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK |
4.11993 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTGS2 |
4.11825 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, BCL2, CDC25B, DRD2, EGFR, ESR1, F3, FLT3, HMGCR, HSPA1A, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.11297 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
AXL, BCL2, CA2, CYP1B1, DRD2, DRD3, EGFR, ESRRB, F3, HCAR2, HMGCR, HSPA1A, KDR, MET, MMP12, MMP9, PIM1, PTGS2, SMAD3, SRC, TEK |
4.10119 |
|
[BP] GO:0045776 |
None
|
ADORA1, DRD2, DRD3, DRD5, PPARA |
4.08063 |
|
[BP] GO:0097746 |
None
|
ADORA1, DRD1, DRD5, EGFR, HMGCR, HTR1A, PTGS2 |
4.08063 |
|
[BP] GO:0035296 |
None
|
ADORA1, DRD1, DRD5, EGFR, HMGCR, HTR1A, PTGS2 |
4.08063 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR, HMGCR |
4.05914 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DRD1, DRD2, DRD3, HTR1A |
4.05914 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, FABP4, FUT7, GBA2, HSPA1A, MMP1, MMP12, MMP2, MMP9, PIK3CB, SRC, XDH |
4.04719 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PTPN1, SMAD3 |
4.04476 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.04368 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ESR1, F3, FLT3, HSPA1A, INSR, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
4.01841 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
AURKB, AXL, BCL2, DRD2, DRD3, ESR1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.96476 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.95998 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, AXL, BCL2, CDC25B, CDK6, CYP1A1, DRD1, DRD2, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, KDR, MET, MMP2, MMP9, PTGS2, RORC, SMAD3, SRC, TEK, TOP2A |
3.95339 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, AXL, BCL2, CA1, CSNK2A1, DRD2, EGFR, F3, FLT3, GPR35, IGF1R, INSR, KDR, MET, MMP2, MMP9, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.94923 |
|
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, DRD2, DRD3, FABP3, PPARA |
3.94914 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, DRD2, EGFR, FLT3, HMGCR, INSR, KDR, PIK3CB, PTPN1, SRC, TEK, XDH |
3.93562 |
|
[BP] GO:0050880 |
None
|
ADORA1, DRD1, DRD5, EGFR, HMGCR, HTR1A, PTGS2 |
3.92687 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
BCL2, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, XDH |
3.9134 |
|
[BP] GO:0035150 |
None
|
ADORA1, DRD1, DRD5, EGFR, HMGCR, HTR1A, PTGS2 |
3.91058 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, AURKB, BCL2, CSNK2A1, CYP2D6, DRD2, DRD3, DUSP3, ESR1, ESR2, ESRRA, FABP4, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PIK3CA, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
3.91058 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, DRD2, DUSP3, EGFR, FLT3, HMGCR, IGF1R, INSR, KDR, PIK3CB, PTPN1, SRC, TEK, XDH |
3.90481 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
AURKB, BCL2, DRD3, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.89438 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, HMGCR, IGF1R, INSR, PIK3CB, PTPN1, SRC |
3.89438 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
3.89066 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.88295 |
|
[BP] GO:0007612 |
None
|
DRD1, DRD2, DRD3, DRD5, HMGCR, INSR, PTGS2 |
3.86014 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, FABP3, HSD11B2, IGF1R, INSR, PPARA, PTGS2, SRC, TEK |
3.80149 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, AXL, BCL2, CA2, CYP19A1, DRD1, DRD2, DRD3, EGFR, HCAR2, INSR, MMP12, PTGS2, SMAD3, SRC |
3.79427 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, HMGCR, IGF1R, INSR, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
3.78278 |
|
[BP] GO:0050890 |
None
|
ADORA1, DRD1, DRD2, DRD3, DRD5, EGFR, HMGCR, INSR, PTGS2 |
3.78278 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, DRD2, DRD3, GPR35, MMP9, PTGS2 |
3.76407 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, PIK3CB, SMAD3 |
3.70762 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, HMGCR, SRC, TNKS, TNKS2 |
3.70652 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, DRD2, DRD3, HMGCR, PPARA, SMAD3, TEK |
3.69916 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
3.63212 |
|
[BP] GO:0009416 |
response to light stimulus
|
AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HMGCR, PTGS2, TYR |
3.63212 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.6321 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK, TNKS, TOP2A |
3.624 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, AURKB, CDC25B, CYP1A1, DRD2, DRD3, DUSP3, EGFR, INSR, SRC |
3.59396 |
|
[BP] GO:0050793 |
regulation of developmental process
|
AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, HMGCR, INSR, KDR, NUAK1, PIK3CA, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, XDH |
3.57196 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, DRD3, PPARA, RORC, TOP2A |
3.56604 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, EGFR, FLT3, HSD11B2, PTGS2, SRC |
3.54346 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, PTGS2, SRC |
3.52478 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS1, PTGS2 |
3.52478 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS1, PTGS2 |
3.52478 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, PPARA, PTGS1, PTGS2 |
3.52129 |
|
[BP] GO:0051940 |
None
|
DRD1, DRD2, DRD3 |
3.51498 |
|
[BP] GO:0051584 |
None
|
DRD1, DRD2, DRD3 |
3.51498 |
|
[BP] GO:0001975 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.5131 |
|
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
3.49865 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, HMGCR, IGF1R, INSR, PIK3CA, PIK3CB, PTPN1, SRC |
3.48717 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, DRD5, EGFR |
3.48598 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
3.48385 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, DRD1, DRD5, EGFR, ESR1, FLT3, IGF1R, INSR, MMP2, PTGS2, SMAD3, SRC |
3.46366 |
|
[BP] GO:0032787 |
None
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, GBA2, GLO1, PPARA, PTGS1, PTGS2 |
3.46366 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, EGFR, FLT3, INSR, PIK3CA, PIK3CB, PTPN1, SRC, TEK, TNKS |
3.45335 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, DRD1, DRD2, EGFR, PTGS2 |
3.45329 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, DRD1, DRD5, EGFR, IGF1R, INSR, MMP2, PTGS2, SRC |
3.39019 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR |
3.38108 |
|
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, HCAR2, HMGCR, HSD17B1, HSD17B2, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
3.38108 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, SRC |
3.36363 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.36202 |
|
[BP] GO:0007611 |
None
|
DRD1, DRD2, DRD3, DRD5, EGFR, HMGCR, INSR, PTGS2 |
3.35862 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.34982 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, PTGS2, SRC |
3.32553 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALPI, CSNK2A1, DRD2, EGFR, FABP3, FABP4, MET, PIK3CA, PIK3CB |
3.32237 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, INSR, PTGS2, SMAD3, XDH |
3.32178 |
|
[BP] GO:0010038 |
response to metal ion
|
BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, MMP9, PTGS2 |
3.30145 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, DRD2, MMP12, PPARA, SMAD3, TEK |
3.29119 |
|
[BP] GO:0048732 |
gland development
|
BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
3.27707 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CYP1B1, F3, HCAR2, HMGCR, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, XDH |
3.27619 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, EGFR, HSPA1A, INSR, TNKS |
3.25946 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, BCL2, CDC25B, DRD2, EGFR, FLT3, HMGCR, INSR, KDR, MMP9, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH |
3.25946 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CYP1B1, DRD1, DRD2, EGFR, FUT7, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
3.25163 |
|
[BP] GO:0001503 |
ossification
|
ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.25157 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CYP1B1, F3, HCAR2, HMGCR, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, XDH |
3.24255 |
|
[BP] GO:0007191 |
None
|
DRD1, DRD3, DRD5 |
3.24255 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.24255 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
BCL2, DRD2, DRD3, PIK3CA, TNKS2 |
3.22071 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
BCL2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, PIK3CB, SMAD3 |
3.21467 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, DRD2 |
3.19871 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, DRD1, DRD2, MET, PIK3CA |
3.17533 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, HMGCR |
3.1633 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
3.14912 |
|
[BP] GO:0055080 |
cation homeostasis
|
BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, PIK3CB, SMAD3 |
3.14912 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
AURKB, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, IGF1R, INSR, KDR, MET, MMP12, PPARA, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
3.13997 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, DRD1, DRD5, EGFR, IGF1R, INSR, MMP2, PTGS2, SRC |
3.13508 |
|
[BP] GO:0008306 |
None
|
DRD1, DRD2, DRD3, DRD5, HMGCR |
3.10913 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CYP1A1, EGFR, HMGCR, HSD11B2, PTGS2, SRC, TYR |
3.10277 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
AKR1B1, AXL, BCL2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
3.10048 |
|
[BP] GO:0003008 |
None
|
ADORA1, AKR1B1, BCL2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, HMGCR, HSD11B2, HTR1A, INSR, PIK3CA, PTGS2, SRC, TEK, TYR |
3.09917 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, AXL, BCL2, CA2, CDK6, CYP19A1, DRD2, DUSP3, ESR1, ESRRA, HCAR2, HSPA1A, MMP12, MMP2, PIK3CA, PIK3CB, PTPN1, SMAD3, SRC |
3.09917 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, PPARA, PTGS2, SRC, TEK |
3.08847 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
3.08847 |
|
[BP] GO:0051098 |
regulation of binding
|
AURKB, BCL2, CYP2D6, MET, MMP9, PPARA, SMAD3, SRC, TNKS |
3.08847 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
BCL2, CDK6, KDR, PIK3CB, SMAD3, SRC, TEK |
3.06179 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR |
3.06155 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, EGFR, HCAR2, MET, PIK3CA, PPARA, SMAD3 |
3.05513 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC, TEK |
3.05513 |
|
[BP] GO:0007610 |
None
|
BCL2, DRD1, DRD2, DRD3, DRD5, EGFR, HMGCR, HTR1A, INSR, PPARA, PTGS2 |
3.04814 |
|
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, DRD2, DRD3, FABP3, PPARA |
3.01298 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ALPI, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F3, FLT3, FUT7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.01298 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
AURKB, AXL, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR1, ESR2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PIK3CB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.01085 |
|
[BP] GO:0040008 |
regulation of growth
|
BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR2, HSPA1A, INSR, PIK3CA, PIM1, SMAD3, TNKS2 |
3.00836 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, PIK3CA, PIK3CB, SMAD3 |
3.00836 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTGS2 |
3.00684 |
|
[BP] GO:0051172 |
None
|
APEX1, AURKB, CSNK2A1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, HMGCR, HSPA1A, IGF1R, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
3.00613 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, INSR, PIK3CA, PIK3CB, PTPN1, SRC, TEK |
3.00181 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4, GBA2 |
2.99048 |
|
[BP] GO:0007212 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.98559 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, DRD3 |
2.98559 |
|
[BP] GO:0046960 |
None
|
DRD1, DRD5 |
2.9738 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.9738 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CYP1B1, F3, HCAR2, HMGCR, MMP9, PIK3CB, PTGS2, SMAD3, SRC, TOP2A, XDH |
2.9738 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
DRD2, DUSP3, EGFR, HMGCR, KDR, PTPN1, SRC, TEK |
2.9576 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CYP1B1, DRD1, DRD2, EGFR, FUT7, KDR, MET, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.9576 |
|
[BP] GO:0014075 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.9524 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.93499 |
|
[BP] GO:0060134 |
None
|
DRD1, DRD2, DRD3 |
2.93499 |
|
[BP] GO:0060158 |
None
|
DRD1, DRD2, DRD5 |
2.93499 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
BCL2, CDK6, CYP1B1, DUSP3, KDR, NUAK1, PIK3CA, PIK3CB, PPARA, SMAD3, SRC, TEK |
2.93326 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, HSD11B2, INSR, PPARA, PTGS2, SRC, TEK |
2.92165 |
|
[BP] GO:0019725 |
cellular homeostasis
|
APEX1, BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, PIK3CA, PIK3CB, SMAD3 |
2.92131 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, PIK3CB, SMAD3 |
2.89348 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.88198 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CYP1B1, DRD1, DRD2, EGFR, FUT7, KDR, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.87074 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.86466 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
2.86119 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.85827 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.84596 |
|
[BP] GO:0051580 |
None
|
DRD1, DRD2, DRD3 |
2.84596 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, PTGS2 |
2.84552 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.84192 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.84192 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, PIK3CB, SMAD3 |
2.81148 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPI, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, FLT3, FUT7, IGF1R, INSR, KDR, MET, MMP1, MMP2, NUAK1, PIK3CA, PIM1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.80123 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, PIK3CB, SMAD3 |
2.79516 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, CA2, DRD2, DRD3, EGFR, HCAR2, HMGCR, MMP12, PTGS2, PTPN1, SMAD3, SRC |
2.79516 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PIK3CA, PIK3CB, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
2.79256 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, HCAR2, MMP12, SRC |
2.78974 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.7827 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, CDC25B, CYP1A1, DRD3, DUSP3, INSR |
2.77402 |
|
[BP] GO:0006584 |
None
|
AKR1B1, DRD1, DRD2, DRD3 |
2.77402 |
|
[BP] GO:0009712 |
None
|
AKR1B1, DRD1, DRD2, DRD3 |
2.77402 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, SRC, TEK |
2.77402 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CYP19A1, EGFR, ESR1, FABP4, PPARA, PTGS2, SMAD3, TEK |
2.74478 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.71485 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, PIK3CB, SMAD3 |
2.70479 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.70243 |
|
[BP] GO:0097366 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.70243 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PTGS2, SMAD3, XDH |
2.70214 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.69331 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.69331 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, PIK3CB, SMAD3 |
2.66981 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ADORA1, BCL2, CA2, CA7, DRD1, DRD2, DRD3, GPR35, HTR1A, MMP9, PTGS2 |
2.65321 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPI, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.64924 |
|
[BP] GO:0036211 |
protein modification process
|
ALPI, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.64924 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, HMGCR, IGF1R, INSR, PIK3CB, PTPN1, SRC |
2.64117 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.61868 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CYP1A1, EGFR, HMGCR, HSD11B2, PTGS2, SRC, TYR |
2.61868 |
|
[BP] GO:0008542 |
None
|
DRD1, DRD2, DRD3, HMGCR |
2.60532 |
|
[BP] GO:0007188 |
None
|
ADORA1, DRD1, DRD2, DRD3, DRD5, HTR1A |
2.60532 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, DRD2, EGFR, INSR, PIK3CA, PIK3CB, PTPN1, SRC |
2.6011 |
|
[BP] GO:0010906 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.58568 |
|
[BP] GO:0003014 |
None
|
ADORA1, AKR1B1, BCL2, DRD2, HSD11B2 |
2.58568 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, GBA2, GLO1, PIM1, PPARA, PTGS1, PTGS2, TYR |
2.58088 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
2.5808 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, INSR, PIK3CA, PIK3CB, PTPN1, SRC |
2.57628 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.57628 |
|
[BP] GO:0060160 |
None
|
DRD2, DRD3 |
2.57628 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.57628 |
|
[BP] GO:1900542 |
None
|
DRD1, DRD2, DRD3, DRD5, ESRRB, INSR, PPARA |
2.56228 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
2.55693 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.55693 |
|
[BP] GO:2000116 |
regulation of cysteine-type endopeptidase activity
|
CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.54206 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGS2, SRC |
2.53894 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.53071 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, AURKB, CSNK2A1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, HMGCR, HSPA1A, IGF1R, KDR, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
2.51432 |
|
[BP] GO:0009314 |
response to radiation
|
AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HMGCR, PTGS2, TYR |
2.50194 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.49879 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.49879 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, MET, SRC |
2.49879 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, MET, SRC |
2.49879 |
|
[BP] GO:0006140 |
None
|
DRD1, DRD2, DRD3, DRD5, ESRRB, INSR, PPARA |
2.49585 |
|
[BP] GO:0045187 |
None
|
ADORA1, DRD2, DRD3 |
2.49585 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.49585 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.49583 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, SRC |
2.49583 |
|
[BP] GO:0050678 |
None
|
CDK6, EGFR, F3, KDR, MMP12, SMAD3, TEK, XDH |
2.47749 |
|
[BP] GO:0007632 |
None
|
DRD1, DRD2, DRD3, HMGCR |
2.46611 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.46611 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, HMGCR, INSR, KDR, PIM1, PTGS2, SMAD3, SRC, TEK, XDH |
2.44017 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
CDK6, DUSP3, EGFR, HMGCR, HSPA1A, IGF1R, MET, NUAK1, PTGS2, PTPN1, XDH |
2.43913 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.43801 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.43801 |
|
[BP] GO:0048148 |
None
|
DRD1, DRD2, DRD3 |
2.43751 |
|
[BP] GO:0035813 |
None
|
ADORA1, DRD2, DRD3 |
2.43751 |
|
[BP] GO:0006650 |
glycerophospholipid metabolic process
|
ACHE, ALPI, CSNK2A1, DRD2, EGFR, MET, PIK3CA, PIK3CB |
2.43178 |
|
[BP] GO:0032922 |
None
|
DRD2, DRD3, PPARA, RORC |
2.41052 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.40952 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
BCL2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, PIK3CB, SMAD3 |
2.39571 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPI, ALPL, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.39571 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.38062 |
|
[BP] GO:0051968 |
None
|
DRD1, EGFR, PTGS2 |
2.38062 |
|
[BP] GO:0042749 |
None
|
ADORA1, DRD2, DRD3 |
2.38062 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.38062 |
|
[BP] GO:0050789 |
regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HCAR2, HMGCR, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
2.36772 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, HCAR2, MMP12, SRC |
2.36671 |
|
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.36294 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.36294 |
|
[BP] GO:0001525 |
angiogenesis
|
CYP1B1, KDR, MMP2, PIK3CA, PIK3CB, PTGS2, TEK |
2.35895 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, APEX1, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
2.3414 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.3285 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.3285 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.3285 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.3285 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.3285 |
|
[BP] GO:0051254 |
None
|
DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, INSR, MET, MMP12, PPARA, RORC, SMAD3, SRC, TNKS, TOP2A |
2.32668 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, DRD2, DRD3, EGFR, HCAR2, HMGCR, MMP12, SRC |
2.32002 |
|
[BP] GO:0002521 |
leukocyte differentiation
|
AXL, BCL2, FLT3, FUT7, GLO1, MMP9, RORC |
2.31906 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TNKS, TNKS2 |
2.31906 |
|
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, CYP2D6 |
2.31906 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CYP19A1, DRD2, EGFR, HCAR2, HMGCR, HTR1A |
2.3009 |
|
[BP] GO:0048729 |
tissue morphogenesis
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.2973 |
|
[BP] GO:1904356 |
regulation of telomere maintenance via telomere lengthening
|
AURKB, SRC, TNKS, TNKS2 |
2.2934 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, FLT3, INSR, PIK3CB, PTPN1, SRC |
2.2934 |
|
[BP] GO:0007187 |
None
|
ADORA1, DRD1, DRD2, DRD3, DRD5, HTR1A |
2.29327 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR1A, MMP12, SRC |
2.28862 |
|
[BP] GO:2000209 |
regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.28862 |
|
[BP] GO:0044062 |
None
|
ADORA1, DRD2, DRD3 |
2.28862 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.28862 |
|
[BP] GO:0030336 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2 |
2.28862 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CYP19A1, PPARA, SMAD3, TEK |
2.28542 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1 |
2.27322 |
|
[BP] GO:0048608 |
reproductive structure development
|
AXL, BCL2, CYP19A1, ESR1, HSD17B2, INSR, SRC |
2.2419 |
|
[BP] GO:0051894 |
None
|
KDR, SMAD3, TEK |
2.23817 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.23817 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, GBA2, GLO1, PIM1, PPARA, PTGS1, PTGS2, TYR |
2.22417 |
|
[BP] GO:0010628 |
positive regulation of gene expression
|
DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, INSR, MET, MMP12, PIK3CB, PPARA, RORC, SMAD3, SRC, TNKS, TOP2A |
2.21132 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, AURKB, CDC25B, CYP1A1, DRD2, DRD3, INSR |
2.20949 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR |
2.209 |
|
[BP] GO:0070201 |
None
|
ACHE, BCL2, DRD2, DRD3, EGFR, HCAR2, HMGCR, MMP12, PTGS2, PTPN1, SMAD3, SRC |
2.20416 |
|
[BP] GO:0050795 |
None
|
ADORA1, DRD2, DRD3, HTR1A |
2.20416 |
|
[BP] GO:2000573 |
positive regulation of DNA biosynthetic process
|
AURKB, SRC, TNKS, TNKS2 |
2.20416 |
|
[BP] GO:0010675 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.19618 |
|
[BP] GO:0050927 |
None
|
F3, KDR, SMAD3 |
2.19618 |
|
[BP] GO:0050886 |
None
|
DRD3, DRD5, HSD11B2 |
2.19618 |
|
[BP] GO:0001990 |
None
|
DRD3, DRD5, HSD11B2 |
2.19618 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, BCL2, CDK6, CYP1B1, DRD2, FABP3, HSPA1A, PTGS2, SMAD3, XDH |
2.19484 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CYP1A1, EGFR, HMGCR, PTGS2, TYR |
2.19078 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, AXL, BCL2, EGFR, FLT3, FUT7, HSPA1A, MMP9, PIK3CA, PIK3CB, RORC, SMAD3, SRC |
2.18681 |
|
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.18569 |
|
[BP] GO:0051926 |
negative regulation of calcium ion transport
|
BCL2, DRD2, GPR35, PTGS2 |
2.18569 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
EGFR, F3, FABP4, KDR, MET, PTGS2, SMAD3 |
2.17317 |
|
[BP] GO:2000146 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2 |
2.16446 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2D6, FABP3, GBA2, GLO1, PIM1, PPARA, PTGS1, PTGS2, TYR |
2.16438 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, PTGS2 |
2.15928 |
|
[BP] GO:0050926 |
None
|
F3, KDR, SMAD3 |
2.15928 |
|
[BP] GO:1904353 |
regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.15928 |
|
[BP] GO:1903393 |
None
|
KDR, SMAD3, TEK |
2.15928 |
|
[BP] GO:0003044 |
None
|
DRD3, DRD5, HSD11B2 |
2.15928 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
DRD2, EGFR, HMGCR, KDR, SRC, TEK |
2.15928 |
|
[BP] GO:0021853 |
None
|
DRD1, DRD2 |
2.15928 |
|
[BP] GO:0043696 |
None
|
CDK6, ESRRB |
2.15928 |
|
[BP] GO:0043697 |
None
|
CDK6, ESRRB |
2.15928 |
|
[BP] GO:0010641 |
None
|
F3, SRC |
2.15928 |
|
[BP] GO:0090325 |
None
|
DRD2, DRD3 |
2.15928 |
|
[BP] GO:1904936 |
None
|
DRD1, DRD2 |
2.15928 |
|
[BP] GO:0042321 |
None
|
ADORA1, DRD2 |
2.15928 |
|
[BP] GO:0015908 |
None
|
DRD2, DRD3, FABP3, PPARA |
2.15126 |
|
[BP] GO:0016311 |
None
|
ALPI, ALPL, APEX1, BCL2, CDC25B, DUSP3, PTPN1 |
2.14246 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, PIK3CB, SMAD3 |
2.14197 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ALPL, AXL, BCL2, CDK6, CYP1A1, CYP1A2, DRD3, EGFR, HMGCR, HSD11B2, MMP12, PTGS2, SMAD3, SRC, TYR |
2.14088 |
|
[BP] GO:0045913 |
None
|
ESRRB, INSR, PPARA, SRC |
2.13119 |
|
[BP] GO:0032465 |
None
|
AURKB, CDC25B, DRD2, DRD3 |
2.13119 |
|
[BP] GO:1904357 |
None
|
SRC, TNKS, TNKS2 |
2.12192 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
AXL, BCL2, CA2, CYP1B1, DRD2, ESRRB, F3, HMGCR, INSR, KDR, PIM1, PTGS2, SMAD3, SRC, TEK |
2.11215 |
|
[BP] GO:0045893 |
None
|
DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, INSR, MET, MMP12, PPARA, RORC, SMAD3, SRC, TNKS, TOP2A |
2.10932 |
|
[BP] GO:1903508 |
None
|
DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, INSR, MET, MMP12, PPARA, RORC, SMAD3, SRC, TNKS, TOP2A |
2.10932 |
|
[BP] GO:1902680 |
None
|
DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, INSR, MET, MMP12, PPARA, RORC, SMAD3, SRC, TNKS, TOP2A |
2.10661 |
|
[BP] GO:0051052 |
regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, PIK3CA, SRC, TNKS, TNKS2 |
2.09029 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
2.08439 |
|
[BP] GO:0043393 |
regulation of protein binding
|
AURKB, BCL2, MET, MMP9, PPARA, SRC |
2.08439 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, BCL2, DRD2, DRD3, GPR35, HMGCR, HSPA1A, MMP9, PTGS2 |
2.08439 |
|
[BP] GO:0033032 |
regulation of myeloid cell apoptotic process
|
BCL2, HCAR2, PIK3CB |
2.08439 |
|
[BP] GO:0042417 |
None
|
DRD1, DRD2, DRD3 |
2.08439 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, HCAR2, HMGCR, HTR1A, MMP12, SRC |
2.0702 |
|
[BP] GO:0045934 |
None
|
APEX1, AURKB, DRD2, DRD3, ESR1, ESR2, ESRRA, FABP4, HSPA1A, MMP12, PPARA, RORC, SMAD3, SRC, TNKS, TNKS2 |
2.05197 |
|
[BP] GO:0051271 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2 |
2.05108 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, SRC, TEK |
2.05108 |
|
[BP] GO:0007189 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.05108 |
|
[BP] GO:0009411 |
response to UV
|
AURKB, BCL2, EGFR, PTGS2, TYR |
2.04893 |
|
[BP] GO:0033280 |
response to vitamin D
|
ALPL, PTGS2, TYR |
2.04453 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, CA2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, HCAR2, HTR1A, INSR, PIK3CA, PIK3CB, SRC |
2.03282 |
|
[BP] GO:0044243 |
multicellular organismal catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.03186 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
2.02589 |
|
[BP] GO:0033029 |
regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.01988 |
|
[BP] GO:0021843 |
None
|
DRD1, DRD2 |
2.01988 |
|
[BP] GO:0051902 |
negative regulation of mitochondrial depolarization
|
BCL2, SRC |
2.01988 |
|
[BP] GO:0046113 |
None
|
AOX1, XDH |
2.01988 |
|
[BP] GO:0021830 |
None
|
DRD1, DRD2 |
2.01988 |
|
[BP] GO:0021826 |
None
|
DRD1, DRD2 |
2.01988 |
|
[BP] GO:0046958 |
None
|
DRD1, DRD5 |
2.01988 |
|
[BP] GO:0016098 |
monoterpenoid metabolic process
|
CYP1A2, CYP2D6 |
2.01988 |
|
[BP] GO:0031099 |
regeneration
|
AXL, BCL2, CSNK2A1, EGFR, FLT3 |
2.0193 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DRD3, EGFR, PPARA, RORC |
2.0193 |
|
[BP] GO:0035265 |
organ growth
|
BCL2, CYP19A1, ESR1 |
2.01835 |
|
[BP] GO:0002209 |
None
|
BCL2, DRD1, HTR1A |
2.01835 |
|
[BP] GO:1901661 |
None
|
AKR1B1, AKR1B10, HMGCR |
2.01835 |
|
[BP] GO:0001662 |
None
|
BCL2, DRD1, HTR1A |
2.01835 |
|
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, SRC, TEK |
2.01835 |
|
[BP] GO:0042743 |
hydrogen peroxide metabolic process
|
CYP1A1, CYP1A2, EGFR |
2.01835 |
|
[BP] GO:0032413 |
None
|
DRD2, DRD3, GPR35, MMP9 |
2.00412 |
|
[BP] GO:0035239 |
tube morphogenesis
|
BCL2, EGFR, ESR1, MET, SMAD3, SRC |
2.00098 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC, TEK |
2.00098 |
|
[BP] GO:0032872 |
regulation of stress-activated MAPK cascade
|
DUSP3, EGFR, HMGCR, IGF1R, PTPN1, XDH |
2.00098 |
|
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ALOX5, ALPI, ALPL, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GLO1, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, IGF1R, INSR, KDR, MET, MMP2, PIK3CA, PIK3CB, PIM1, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TYR |
4.02472 |
|
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ALPI, ALPL, AXL, CA12, CA14, CA2, CA4, CA9, CSNK2A1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F3, FLT3, GBA2, GLO1, GPR35, HCAR2, HTR1A, IGF1R, INSR, KDR, MET, MMP2, PIK3CA, PIK3CB, PIM1, PTPN1, SMAD3, SRC, TEK |
3.54985 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, EGFR, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGS1, PTGS2 |
3.42366 |
|
[CC] GO:0044425 |
membrane part
|
ACHE, ADORA1, ADORA3, ALPI, ALPL, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, F3, FLT3, FUT7, GBA2, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B2, HTR1A, IGF1R, INSR, KDR, MET, PIK3CA, PIK3CB, PTGS1, PTGS2, PTPN1, SRC, TEK, TYR |
3.01298 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA2, CA4, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TYR, XDH |
3.00613 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, EGFR, FLT3, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGS1, PTGS2, PTPN1 |
2.9576 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, AURKB, BCL2, CA1, CA2, CA4, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, MMP2, MMP9, NQO2, PIK3CA, PIK3CB, PIM1, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TNKS, TNKS2, TOP2A, TYR, XDH |
2.84404 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, BCL2, CA4, CYP19A1, CYP2D6, FLT3, GBA2, HMGCR, HSPA1A, KDR, PTGS2, PTPN1, XDH |
2.77402 |
|
[CC] GO:0031253 |
None
|
ADORA1, CA4, CA9, DRD1, DRD2, DRD5, INSR, SRC |
2.59244 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, AXL, CA4, DRD1, DRD2, DRD3, DRD5, F3, FLT3, GPR35, HTR1A, IGF1R, INSR, KDR, MET, TEK |
2.36671 |
|
[CC] GO:0043226 |
organelle
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA2, CA4, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TYR, XDH |
2.3285 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, TEK |
2.26177 |
|
[CC] GO:0044464 |
cell part
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, HCAR2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
2.21576 |
|
[CC] GO:0098590 |
plasma membrane region
|
ADORA1, CA2, CA4, CA9, DRD1, DRD2, DRD5, EGFR, INSR, MET, PTGS2, SRC, TEK |
2.12721 |
|
[CC] GO:0097443 |
sorting endosome
|
KDR, PTPN1 |
2.01988 |
|
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSD17B1, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
15.7014 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, ALPI, AOX1, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PIM1, PPARA, PTPN1, RORC, SMAD3, TNKS, TYR, XDH |
15.129 |
|
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DUSP3, EGFR, F3, FLT3, FUT7, GBA2, GLO1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PTGS1, PTGS2, PTPN1, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
13.494 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
9.89199 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, ESR1, ESR2, ESRRA, ESRRB, GLO1, HTR1A, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, TNKS, TNKS2, TOP2A, TYR, XDH |
9.1437 |
|
[MF] GO:0008270 |
zinc ion binding
|
ALPI, CA1, CA12, CA2, CA4, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PPARA, PTPN1, RORC, SMAD3, TNKS |
9.05482 |
|
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, SRC, TEK, TOP2A |
8.66708 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TYR, XDH |
8.16003 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
7.22223 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, IGF1R, INSR, KDR, MET, PPARA, RORC, TEK |
6.66431 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.66431 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.49955 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.17454 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AXL, CDK6, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, IGF1R, INSR, KDR, MET, PPARA, RORC, TEK |
6.10557 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX5, ALPI, ALPL, AOX1, APEX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, TNKS, TNKS2, TOP2A, TYR, XDH |
6.09581 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
5.9634 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, IGF1R, INSR, KDR, MET, PPARA, RORC, TEK |
5.73074 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, HMGCR, HSD11B2, HSD17B1, NQO2, PTGS1, PTGS2, SRC, XDH |
5.68534 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, IGF1R, INSR, KDR, MET, PPARA, RORC, SMAD3, TEK |
5.6036 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
5.24359 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.08492 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.08492 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS1, PTGS2, SRC |
5.03238 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
5.02246 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIM1, SRC, TEK |
4.99477 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
4.99429 |
|
[MF] GO:0005496 |
steroid binding
|
ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, RORC |
4.99429 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, GLO1 |
4.9797 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB |
4.8876 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS1, PTGS2, SRC |
4.83228 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK |
4.79404 |
|
[MF] GO:0004952 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.73852 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.67152 |
|
[MF] GO:0035240 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.6044 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, AOX1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, XDH |
4.57281 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, PTGS1, PTGS2, TYR |
4.49869 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, XDH |
4.4101 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK |
4.35011 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
4.26701 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD1, DRD2, DRD3, DRD5, HTR1A |
4.20332 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.17671 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
4.08695 |
|
[MF] GO:0036094 |
small molecule binding
|
ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FABP3, FABP4, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, XDH |
4.08063 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6 |
3.95274 |
|
[MF] GO:1901338 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.9246 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, EGFR, HSD17B1, IGF1R, INSR, NQO2 |
3.89055 |
|
[MF] GO:0000166 |
nucleotide binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, XDH |
3.65957 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, XDH |
3.65766 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, TYR |
3.63212 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, F3, FLT3, GPR35, HCAR2, HTR1A, IGF1R, INSR, KDR, MET, TEK |
3.62081 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, F3, FLT3, GPR35, HCAR2, HTR1A, IGF1R, INSR, KDR, MET, TEK |
3.62081 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK |
3.55503 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.45594 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
3.38949 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.36528 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
3.36363 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.34868 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, AOX1, BCL2, CSNK2A1, DRD2, EGFR, ESR1, ESR2, FLT3, HMGCR, IGF1R, KDR, MET, MMP9, NQO2, PTGS2, SMAD3, TOP2A, TYR, XDH |
3.25898 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ADORA1, AOX1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD11B2, HSD17B1, HSPA1A, HTR1A, IGF1R, INSR, KDR, MET, MMP12, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, PPARA, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP2A, XDH |
3.00034 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.9738 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.9738 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.9738 |
|
[MF] GO:0019899 |
enzyme binding
|
ALPI, AURKB, BCL2, CDC25B, CYP1A1, CYP1A2, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, HMGCR, HSPA1A, MET, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
2.97294 |
|
[MF] GO:0008289 |
lipid binding
|
AXL, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, HSD11B2, HSD17B1, PPARA, RORC |
2.89348 |
|
[MF] GO:0005524 |
ATP binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A |
2.81148 |
|
[MF] GO:0043168 |
anion binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, F3, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A, XDH |
2.7943 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.73704 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A |
2.69977 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIK3CA, PIK3CB, PIM1, SRC, TEK, TOP2A |
2.66636 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, F3, FLT3, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PTPN1, SRC, TEK |
2.37573 |
|
[MF] GO:0030594 |
None
|
DRD1, DRD2, DRD3, DRD5, HTR1A |
2.36683 |
|
[MF] GO:0042803 |
protein homodimerization activity
|
ACHE, AOX1, BCL2, DRD2, FLT3, HMGCR, NQO2, PTGS2, SMAD3, TOP2A, TYR, XDH |
2.3285 |
|
[MF] GO:0001588 |
None
|
DRD1, DRD5 |
2.3285 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.3285 |
|
[MF] GO:0019903 |
protein phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PTPN1 |
2.23805 |
|
[MF] GO:0005518 |
collagen binding
|
ACHE, MMP12, MMP9, SMAD3 |
2.22417 |
|
[MF] GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
EGFR, MET, PIK3CA, PIK3CB |
2.16329 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2 |
2.15928 |
|
[MF] GO:0043559 |
insulin binding
|
IGF1R, INSR |
2.15928 |
|
[MF] GO:0046983 |
protein dimerization activity
|
ACHE, ADORA1, AOX1, AXL, BCL2, DRD2, EGFR, FLT3, HMGCR, NQO2, PTGS2, SMAD3, TOP2A, TYR, XDH |
2.13119 |
|
[MF] GO:0052813 |
phosphatidylinositol bisphosphate kinase activity
|
EGFR, MET, PIK3CA, PIK3CB |
2.10985 |
|
[MF] GO:0019838 |
growth factor binding
|
EGFR, IGF1R, INSR, KDR, TEK |
2.08557 |
|
[MF] GO:0051721 |
None
|
BCL2, HMGCR, PTPN1 |
2.08439 |
|
[MF] GO:0043548 |
phosphatidylinositol 3-kinase binding
|
AXL, IGF1R, INSR |
2.04453 |
|
[MF] GO:0004064 |
arylesterase activity
|
CA1, CA2 |
2.01988 |
|
[MF] GO:0043546 |
None
|
AOX1, XDH |
2.01988 |
|
[MF] GO:0004035 |
alkaline phosphatase activity
|
ALPI, ALPL |
2.01988 |
|
[MF] GO:0035004 |
phosphatidylinositol 3-kinase activity
|
EGFR, MET, PIK3CA, PIK3CB |
2.01981 |
