GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9, DHFR |
8.26451 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALPL, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MAOB, PPARA, PTGS2, RORC, SRC |
8.26451 |
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.74978 |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, ALOX5, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, IDO1, PDE5A, PIM1, PPARA, PTGS2, TBXAS1, XDH |
7.68712 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, AXL, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, GSK3B, IDO1, IGF1R, MAOB, PPARA, PTGS2, RORC, SRC |
7.02195 |
[BP] GO:0042221 |
response to chemical
|
AKR1B1, ALPL, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MAOB, PPARA, PTGS2, RORC, SRC |
6.65338 |
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, CA12, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HCAR2, HSD17B1, KDR, KIT, MAOB, MET, PPARA, PTGS2, SRC, XDH |
6.58976 |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, FABP4, KDR, KIT, MAOB, PTGS2, SRC |
6.57428 |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, ALOX5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, HSD17B1, KIT, MET, PPARA, PTGS2, TBXAS1 |
6.57428 |
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, FABP3, FLT3, IDO1, MAOB, PTGS2, RORC, SRC |
6.57428 |
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, HCAR2, IDO1, IGF1R, KDR, KIT, MET, PIM1, PPARA, PTGS2, SRC, XDH |
6.49887 |
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, GSK3B, HCAR2, KDR, KIT, MET, MMP12, PDE5A, PTGS2, SRC, XDH |
6.49887 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, PIM1, SRC |
6.49887 |
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, GSK3B, HCAR2, KDR, KIT, MET, MMP12, PDE5A, PTGS2, SRC, XDH |
6.49887 |
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, GSK3B, IDO1, IGF1R, KDR, KIT, MET, PIM1, PPARA, PTGS2, SRC |
6.2356 |
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, HCAR2, IDO1, IGF1R, KDR, KIT, MET, PIM1, PTGS2, SRC, XDH |
6.20325 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, CA2, CA9, CSNK2A1, CYP1A2, FABP3, FLT3, KIT, MAOB, PPARA, PTGS2, SRC |
6.18043 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, CA2, CA9, CSNK2A1, CYP1A2, FABP3, FLT3, GSK3B, IGF1R, KIT, MAOB, PPARA, PTGS2, SRC |
6.08927 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, GSK3B, IDO1, IGF1R, KDR, KIT, MET, PIM1, PTGS2, SRC |
5.78579 |
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, MAOB, PTGS2, RORC, SRC |
5.71897 |
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HCAR2, IDO1, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC, XDH |
5.70905 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, GSK3B, HSD17B1, IDO1, MAOB, PTGS2, TBXAS1, XDH |
5.67327 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, FABP3, FLT3, HCAR2, KIT, PPARA, PTGS2, RORC, SRC |
5.57178 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, FABP3, FLT3, GSK3B, HCAR2, IDO1, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC, XDH |
5.47948 |
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, ALOX5, ALPL, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IDO1, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC, TBXAS1, XDH |
5.44998 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, CSNK2A1, CYP1B1, FABP3, FLT3, IDO1, IGF1R, KDR, KIT, MMP12, PDE5A, PIM1, PTGS2, SRC, XDH |
4.99224 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, ALOX5, ALPL, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IDO1, IGF1R, KDR, KIT, MAOB, MET, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC, TBXAS1, XDH |
4.98432 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, DHFR, FABP3, FABP4, GSK3B, IDO1, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC, XDH |
4.87085 |
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, HCAR2, IDO1, IGF1R, KDR, PIM1, PTGS2, SRC, XDH |
4.66527 |
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, DHFR, FABP3, FABP4, GSK3B, HCAR2, IDO1, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC, XDH |
4.66527 |
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS2, TBXAS1 |
4.52168 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, ALOX5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, KIT, MET, PPARA, PTGS2, TBXAS1 |
4.44763 |
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS2, TBXAS1 |
4.35917 |
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, GSK3B, IDO1, MAOB, MMP12, PDE5A, SRC, XDH |
4.34654 |
[BP] GO:0019369 |
arachidonic acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, PTGS2, TBXAS1 |
4.3208 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALPL, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, GSK3B, KDR, KIT, MAOB, PIM1, PPARA, PTGS2, RORC, SRC |
4.3208 |
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, GSK3B, HCAR2, IGF1R, KDR, KIT, MAOB, MET, MMP12, PPARA, PTGS2, SRC |
4.3208 |
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CYP1A1, CYP1A2, IDO1, MAOB, PTGS2, SRC |
4.30524 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
4.28204 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALPL, AXL, CYP1A1, CYP1B1, FABP4, FLT3, GSK3B, IGF1R, KDR, KIT, PTGS2, RORC, SRC |
4.26218 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
4.2494 |
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, ALPL, AURKB, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MAOB, MMP12, PPARA, PTGS2, RORC, SRC |
4.23952 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, GSK3B, IDO1, IGF1R, KDR, PIM1, PTGS2, SRC |
4.22071 |
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1, MAOB |
4.17664 |
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, PPARA, PTGS2, TBXAS1 |
4.17061 |
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CYP1A1, CYP1A2, IDO1, MAOB, PTGS2, SRC |
4.17061 |
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, PPARA |
4.14003 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALPL, AXL, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, GSK3B, IGF1R, KDR, KIT, PTGS2, RORC, SRC |
4.09825 |
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, KIT, PPARA, PTGS2, SRC |
4.09815 |
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALPL, AURKB, AXL, CSNK2A1, DHFR, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PDE5A, PIM1, PTGS2, SRC, XDH |
4.09461 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, GSK3B, HCAR2, IGF1R, KDR, KIT, MET, MMP12, PDE5A, PTGS2, SRC, XDH |
4.06408 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, AXL, CSNK2A1, CYP1B1, FLT3, GSK3B, KDR, KIT, MET, MMP12, PDE5A, PTGS2, SRC, XDH |
4.02004 |
[BP] GO:0042493 |
response to drug
|
AKR1B1, AXL, CA9, CYP1A1, CYP1B1, DHFR, FABP3, KDR, MAOB, PTGS2, SRC |
4.01063 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, GSK3B, HCAR2, IGF1R, KDR, KIT, MET, MMP12, PDE5A, PTGS2, SRC, XDH |
3.98709 |
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALPL, AURKB, AXL, CA2, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP4, FLT3, GSK3B, KDR, KIT, MAOB, MET, PIM1, PPARA, PTGS2, RORC, SRC |
3.96696 |
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALPL, AURKB, AXL, CSNK2A1, DHFR, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PDE5A, PIM1, PTGS2, SRC, XDH |
3.85529 |
[BP] GO:0050665 |
hydrogen peroxide biosynthetic process
|
CYP1A1, CYP1A2, MAOB |
3.83983 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALPL, AURKB, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP4, FLT3, GSK3B, IGF1R, KDR, KIT, PTGS2, RORC, SRC |
3.75651 |
[BP] GO:0032787 |
None
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, IDO1, PPARA, PTGS2, TBXAS1 |
3.73067 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AXL, CYP1B1, FLT3, KDR, KIT, MET, PDE5A, PTGS2, SRC, XDH |
3.72663 |
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS2, TBXAS1 |
3.59601 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.54658 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, AXL, CSNK2A1, CYP1B1, FABP4, FLT3, GSK3B, IDO1, KDR, KIT, MET, MMP12, PDE5A, PTGS2, SRC, XDH |
3.54364 |
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, CYP19A1, CYP1A2, IDO1, MAOB, XDH |
3.49882 |
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, IDO1, PIM1, PPARA, PTGS2, TBXAS1 |
3.42867 |
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, PPARA |
3.31634 |
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, AXL, CYP1A1, CYP1B1, KDR, MAOB, SRC |
3.31594 |
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, KIT, SRC |
3.28946 |
[BP] GO:0048511 |
rhythmic process
|
AXL, CSNK2A1, GSK3B, KIT, PPARA, RORC, SRC |
3.26486 |
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, PTGS2, TBXAS1 |
3.25909 |
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AURKB, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, GSK3B, IDO1, MAOB, PDE5A, SRC, XDH |
3.25909 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1 |
3.21438 |
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AURKB, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, GSK3B, IDO1, MAOB, PDE5A, XDH |
3.21254 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, IGF1R, KDR, KIT, MET, PDE5A, PTGS2, SRC, XDH |
3.15157 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1 |
3.12161 |
[BP] GO:0006468 |
protein phosphorylation
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC |
3.12161 |
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, IDO1, PIM1, PPARA, PTGS2, TBXAS1 |
3.08091 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, CYP1A1, CYP1A2, CYP1B1 |
3.04421 |
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, PTGS2, SRC |
3.03475 |
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, AURKB, CSNK2A1, CYP1B1, FABP4, GSK3B, IGF1R, MET, PIM1, PPARA, PTGS2, SRC |
3.0342 |
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, IDO1, PIM1, PPARA, PTGS2, TBXAS1 |
3.02302 |
[BP] GO:0010038 |
response to metal ion
|
CA2, CYP1A1, CYP1A2, FABP4, KIT, MAOB, PTGS2 |
2.99919 |
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, FLT3, KDR, KIT, PPARA, SRC |
2.97401 |
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, CA2, CA7, HCAR2, KDR, PTGS2, SRC |
2.86928 |
[BP] GO:0006091 |
generation of precursor metabolites and energy
|
AKR1B1, CYP19A1, CYP1A2, GSK3B, IDO1, MAOB, XDH |
2.86691 |
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, CA2, FLT3, MAOB, PTGS2, SRC |
2.86103 |
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, DHFR, FABP4, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MET, MMP12, PDE5A, PPARA, PTGS2, SRC, XDH |
2.86083 |
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, PTGS2, SRC |
2.8321 |
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, CYP19A1, DHFR, FABP4, GSK3B, IDO1, IGF1R, MET, MMP12, PPARA, PTGS2, SRC, XDH |
2.82426 |
[BP] GO:1901652 |
response to peptide
|
AKR1B1, FABP3, GSK3B, IGF1R, PPARA, PTGS2, SRC |
2.78141 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, CYP1A1, CYP1B1, FLT3, PTGS2, RORC, SRC |
2.76882 |
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, ALOX5, ALPL, AXL, CYP19A1, CYP1A2, CYP1B1, FABP4, IDO1, IGF1R, KIT, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC |
2.76725 |
[BP] GO:0009607 |
response to biotic stimulus
|
ALPL, AXL, CYP1A1, CYP1A2, GSK3B, IDO1, MAOB, MMP12, PTGS2, SRC |
2.7587 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, HCAR2, HSD17B1 |
2.69045 |
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.67683 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.67683 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.63335 |
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
AXL, CA2, CYP1B1, HCAR2, IDO1, KDR, KIT, MET, MMP12, PDE5A, PIM1, PTGS2, SRC |
2.63335 |
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, SRC |
2.62877 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD17B1 |
2.61924 |
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, CYP1A1, CYP1A2, CYP1B1, DHFR, IDO1, MAOB |
2.60208 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, PTGS2, SRC |
2.58328 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.58011 |
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, PTGS2, SRC |
2.57705 |
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, KIT, SRC |
2.55359 |
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1 |
2.53537 |
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, AURKB, CSNK2A1, DHFR, FABP3, FLT3, GSK3B, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PPARA, PTGS2, RORC, SRC, XDH |
2.52134 |
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, FLT3, MAOB, PTGS2, SRC |
2.49465 |
[BP] GO:0045932 |
None
|
ADORA1, PDE5A, PTGS2 |
2.48971 |
[BP] GO:0046427 |
positive regulation of JAK-STAT cascade
|
AKR1B1, CYP1B1, FLT3, KIT |
2.4533 |
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4 |
2.44148 |
[BP] GO:1904894 |
positive regulation of STAT cascade
|
AKR1B1, CYP1B1, FLT3, KIT |
2.42098 |
[BP] GO:0016310 |
phosphorylation
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC |
2.42098 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
CA2, CA7 |
2.39985 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.39985 |
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HCAR2, IDO1 |
2.36878 |
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, DHFR, FABP3, FLT3, GSK3B, IGF1R, PPARA, PTGS2, SRC |
2.36219 |
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, AXL, CYP1B1, KDR, PTGS2, SRC |
2.35865 |
[BP] GO:0001816 |
cytokine production
|
FABP4, IDO1, KIT, PTGS2 |
2.3565 |
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, AURKB, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HCAR2, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC, XDH |
2.35523 |
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, AXL, CA2, CYP19A1, GSK3B, HCAR2, MMP12, PTGS2, SRC |
2.35523 |
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC |
2.29226 |
[BP] GO:0042743 |
hydrogen peroxide metabolic process
|
CYP1A1, CYP1A2, MAOB |
2.29226 |
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, FABP4, IDO1, KDR, MET, MMP12, PPARA, PTGS2 |
2.28051 |
[BP] GO:0042133 |
neurotransmitter metabolic process
|
ACHE, CYP1B1, DHFR, MAOB |
2.27564 |
[BP] GO:0044283 |
None
|
AKR1B1, ALOX5, CYP19A1, CYP1A1, DHFR, IDO1, PTGS2 |
2.26903 |
[BP] GO:1901654 |
None
|
AKR1B1, CA9, CSNK2A1, MAOB, SRC |
2.26903 |
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, CYP1A1, DHFR, PPARA |
2.26006 |
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, CA2, CA7, KIT, PTGS2 |
2.2357 |
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, CA2, CA7, KIT, PTGS2 |
2.2357 |
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7 |
2.23053 |
[BP] GO:0002318 |
myeloid progenitor cell differentiation
|
FLT3, KIT |
2.22751 |
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, AXL, CA2, CYP1B1, GSK3B, HCAR2, IDO1, KDR, KIT, MET, MMP12, PDE5A, PIM1, PTGS2, SRC, XDH |
2.21032 |
[BP] GO:0043207 |
response to external biotic stimulus
|
ALPL, AXL, CYP1A1, CYP1A2, IDO1, MAOB, MMP12, PTGS2, SRC |
2.20334 |
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC |
2.20029 |
[BP] GO:1901361 |
None
|
CYP19A1, CYP1A1, CYP1A2, IDO1, MAOB, PDE5A, XDH |
2.20029 |
[BP] GO:0010906 |
None
|
GSK3B, PPARA, RORC, SRC |
2.16222 |
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, DHFR, FABP3, FLT3, GSK3B, IGF1R, PPARA, PTGS2, SRC |
2.16222 |
[BP] GO:0032091 |
negative regulation of protein binding
|
AURKB, GSK3B, MET, PPARA |
2.13085 |
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, DHFR, FABP3, KDR, PTGS2, SRC |
2.10087 |
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, AURKB, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PPARA, PTGS2, RORC, SRC, XDH |
2.09666 |
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, AURKB, AXL, CSNK2A1, CYP1A1, CYP1A2, DHFR, FLT3, GSK3B, IDO1, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, SRC, XDH |
2.08303 |
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
CYP1A1, CYP1A2, CYP1B1, MAOB |
2.07658 |
[BP] GO:0034405 |
response to fluid shear stress
|
CA2, PTGS2, SRC |
2.07658 |
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, ALOX5, ALPL, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IDO1, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC, TBXAS1, XDH |
2.07658 |
[BP] GO:0008283 |
cell proliferation
|
ACHE, AURKB, CYP1A1, FLT3, KIT, MET, PIM1, SRC |
2.07645 |
[BP] GO:0051188 |
None
|
CYP1A1, CYP1A2, DHFR, MAOB, PTGS2 |
2.07293 |
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DHFR, GSK3B, IDO1, KIT, PPARA, PTGS2, SRC |
2.06624 |
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, ALOX5, ALPL, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IDO1, IGF1R, KDR, KIT, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC, TBXAS1, XDH |
2.05202 |
[BP] GO:0043393 |
regulation of protein binding
|
AURKB, GSK3B, MET, PPARA, SRC |
2.03944 |
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, CA2, CA7, KDR, SRC |
2.01195 |
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, AURKB, CA9, CSNK2A1, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HCAR2, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC, XDH |
2.0062 |
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, FLT3, IGF1R, KIT, PDE5A, SRC |
2.0062 |
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, AXL, CYP1B1, SRC |
2.0062 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AXL, CYP1B1, SRC |
2.0062 |
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ALPL, AXL, CA12, CA14, CA2, CA4, CA9, CSNK2A1, FLT3, GSK3B, HCAR2, IGF1R, KDR, KIT, MET, PIM1, SRC |
1.39835 |
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9 |
1.34455 |
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ALOX5, ALPL, AXL, CA12, CA14, CA2, CA4, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, GSK3B, HCAR2, IGF1R, KDR, KIT, MAOB, MET, PIM1, PTGS2, SRC, TBXAS1 |
1.32883 |
[CC] GO:0042629 |
None
|
AKR1B1, KIT |
1.21557 |
[CC] GO:0044228 |
host cell surface
|
AXL |
1.00866 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
10.7265 |
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX5, ALPL, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IDO1, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC, TBXAS1, XDH |
10.5029 |
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, ALOX5, ALPL, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, GSK3B, HSD17B1, IDO1, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PIM1, PTGS2, SRC, TBXAS1, XDH |
8.83609 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.19095 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, MMP12, PIM1, PPARA, RORC, TBXAS1, XDH |
7.19095 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.49887 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, PTGS2, SRC, TBXAS1 |
6.49887 |
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, HSD17B1, IDO1, MAOB, PTGS2, SRC, TBXAS1, XDH |
6.49887 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, PTGS2, SRC, TBXAS1 |
6.2978 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, HSD17B1, IDO1, MAOB, PTGS2, TBXAS1, XDH |
5.71212 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET |
5.57178 |
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, PPARA, SRC |
5.47948 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET |
4.99224 |
[MF] GO:0005506 |
iron ion binding
|
ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, TBXAS1, XDH |
4.61001 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC |
4.34626 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
4.3208 |
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, CYP19A1, CYP1A2, IDO1, MAOB, XDH |
4.3208 |
[MF] GO:0016829 |
lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
4.29883 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, ALPL, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, KIT, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, TBXAS1, XDH |
4.28992 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
4.23462 |
[MF] GO:0036094 |
small molecule binding
|
ADORA1, AURKB, AXL, CSNK2A1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IGF1R, KDR, KIT, MAOB, MET, PDE5A, PIM1, SRC, XDH |
4.1911 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
4.07416 |
[MF] GO:0046872 |
metal ion binding
|
ALOX5, ALPL, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, KIT, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, TBXAS1, XDH |
3.90582 |
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC |
3.76674 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, PTGS2, TBXAS1 |
3.59601 |
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC |
3.43373 |
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, TBXAS1 |
3.34572 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.22692 |
[MF] GO:0000166 |
nucleotide binding
|
AURKB, AXL, CSNK2A1, DHFR, FLT3, GSK3B, HSD17B1, IGF1R, KDR, KIT, MAOB, MET, PDE5A, PIM1, SRC, XDH |
3.10313 |
[MF] GO:1901265 |
nucleoside phosphate binding
|
AURKB, AXL, CSNK2A1, DHFR, FLT3, GSK3B, HSD17B1, IGF1R, KDR, KIT, MAOB, MET, PDE5A, PIM1, SRC, XDH |
3.10313 |
[MF] GO:0043168 |
anion binding
|
AURKB, AXL, CSNK2A1, DHFR, FABP3, FABP4, FLT3, GSK3B, HSD17B1, IGF1R, KDR, KIT, MAOB, MET, PDE5A, PIM1, SRC, XDH |
2.97401 |
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CSNK2A1, FLT3, GSK3B, IGF1R, KDR, KIT, MET, PIM1, SRC |
2.86083 |
[MF] GO:1901363 |
heterocyclic compound binding
|
ADORA1, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, GSK3B, HSD17B1, IDO1, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC, TBXAS1, XDH |
2.63335 |
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, FLT3, GSK3B, HSD17B1, IDO1, IGF1R, KDR, KIT, MAOB, MET, MMP12, PDE5A, PIM1, PPARA, PTGS2, RORC, SRC, TBXAS1, XDH |
2.57558 |
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX5, IDO1, PTGS2 |
2.44316 |
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX5, IDO1, PTGS2 |
2.40448 |
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, CSNK2A1, FLT3, IGF1R, KDR, MMP12, PIM1, PPARA, SRC |
2.27564 |
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA7, CA9, MMP12, PPARA, RORC |
2.19843 |
[MF] GO:0004064 |
arylesterase activity
|
CA1, CA2 |
2.08181 |