GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, FABP3, FUT7, GLO1, HMGCR, IDO1, PIM1, PPARA, PTGS2, XDH |
9.31189 |
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, CYP1B1, FLT3, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC, TERT, TOP2A, XDH |
8.78391 |
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, CYP1B1, FLT3, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PTGS2, PTPN1, SRC, TERT, TOP2A, XDH |
8.50034 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9, DHFR |
8.16635 |
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC, TERT |
8.12944 |
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, CYP1B1, FLT3, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MMP9, PIM1, PTGS2, PTPN1, SRC, TERT, TOP2A, XDH |
7.76642 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PTGS2, PTPN1, SRC, TERT |
7.76642 |
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.72164 |
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
7.56132 |
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, APEX1, APP, AURKB, AXL, CA2, CA7, CDC25B, CYP19A1, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
7.4764 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, APEX1, APP, AURKB, AXL, CA2, CA7, CDC25B, CYP19A1, CYP1A1, CYP1B1, FABP3, FLT3, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
7.34101 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AXL, CA9, CYP1A1, CYP1B1, DHFR, FABP3, GSK3B, HMGCR, IDO1, IGF1R, MMP2, MMP9, PPARA, PTGS2, RORC, SRC |
7.25355 |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, APEX1, APP, AXL, CA2, CYP1A1, CYP1B1, FABP4, KDR, MMP9, PTGS2, SRC, TERT |
7.23997 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MMP9, PIM1, PTGS2, PTPN1, SRC, TERT |
7.05438 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, APEX1, APP, AXL, CA2, CA9, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HMGCR, IDO1, IGF1R, KDR, MMP2, PPARA, PTGS2, RORC, SRC |
6.64383 |
[BP] GO:0042221 |
response to chemical
|
AKR1B1, APEX1, APP, AXL, CA2, CA9, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HMGCR, IDO1, IGF1R, KDR, MMP2, MMP9, PPARA, PTGS2, RORC, SRC, TERT |
6.51898 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, CDC25B, CYP1B1, FABP3, FLT3, HMGCR, IDO1, IGF1R, KDR, MMP12, MMP2, MMP9, PIM1, PTGS2, SRC, TERT, XDH |
6.48638 |
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, APP, AXL, CA2, CA7, CYP19A1, CYP1B1, FLT3, GSK3B, HMGCR, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, TERT, XDH |
6.4486 |
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, APP, AXL, CA2, CA7, CYP19A1, CYP1B1, FLT3, GSK3B, HMGCR, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, TERT, XDH |
6.43373 |
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, APEX1, APP, AURKB, AXL, CA12, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, FABP3, FABP4, FLT3, GSK3B, HMGCR, KDR, MET, PPARA, PTGS2, SRC, TERT, XDH |
6.26916 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP1, MMP2, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
6.24056 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AURKB, AXL, CYP19A1, CYP1B1, DHFR, FABP3, FABP4, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP12, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
6.18362 |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, CYP19A1, CYP1A1, CYP1B1, CYP3A4, FABP3, FABP4, FUT7, HMGCR, MET, PPARA, PTGS2 |
5.99664 |
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, APEX1, APP, AURKB, AXL, CA2, CA9, CDC25B, CYP19A1, CYP1A1, CYP1B1, DHFR, FABP4, FLT3, FUT7, GLO1, GSK3B, HMGCR, KDR, MET, MMP2, MMP9, PIM1, PPARA, PTGS2, RORC, SRC, TERT, TOP2A |
5.69263 |
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, APP, CYP19A1, DHFR, FABP4, GSK3B, HMGCR, IDO1, IGF1R, MET, MMP12, MMP2, PPARA, PTGS2, PTPN1, SRC, TERT, XDH |
5.65819 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, APEX1, APP, AURKB, AXL, CA2, CA9, CYP1A1, CYP1B1, DHFR, FABP4, FLT3, GSK3B, IGF1R, KDR, MMP2, MMP9, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A |
5.38625 |
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AURKB, AXL, CYP19A1, CYP1B1, DHFR, FABP3, FABP4, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP12, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
5.15744 |
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, HMGCR, IDO1 |
5.05412 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX5, APEX1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, GSK3B, HMGCR, IDO1, PTGS2, XDH |
5.05412 |
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AURKB, CYP19A1, CYP1A1, CYP1B1, CYP3A4, FABP3, FABP4, FUT7, GSK3B, IDO1, MMP1, MMP12, MMP2, MMP9, SRC, XDH |
5.01913 |
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
4.90207 |
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, HMGCR, MMP2, MMP9, PTGS2, TERT |
4.84812 |
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, GSK3B, MET, MMP9, PPARA, SRC, TERT |
4.82453 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, APEX1, APP, AXL, CYP1A1, CYP1B1, FABP4, FLT3, GSK3B, IGF1R, KDR, MMP2, MMP9, PTGS2, RORC, SRC, TERT |
4.81599 |
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, APEX1, APP, AXL, CA2, CA7, CYP19A1, CYP1B1, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, SRC, TERT |
4.73021 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, APP, AXL, CYP1B1, FLT3, GSK3B, HMGCR, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, TERT, XDH |
4.72004 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, APP, AXL, CYP1B1, FABP4, FLT3, GSK3B, HMGCR, IDO1, KDR, MET, MMP12, MMP2, MMP9, PTGS2, PTPN1, SRC, TERT, XDH |
4.67512 |
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AURKB, AXL, CA2, CA9, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GSK3B, HMGCR, IDO1, IGF1R, KDR, MMP12, MMP2, MMP9, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A |
4.66211 |
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
4.65901 |
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CYP1B1, FABP4, GSK3B, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC |
4.61289 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, APEX1, APP, AXL, CYP1A1, CYP1B1, FABP4, FLT3, GSK3B, IGF1R, KDR, MMP2, PTGS2, RORC, SRC |
4.38231 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1B1, CYP3A4, HMGCR |
4.29376 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
4.29376 |
[BP] GO:0042493 |
response to drug
|
AKR1B1, APEX1, AXL, CA9, CYP1A1, CYP1B1, DHFR, FABP3, HMGCR, KDR, PTGS2, SRC |
4.29376 |
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
4.29376 |
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, GSK3B, IGF1R, PPARA, PTGS2, SRC |
4.29376 |
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AXL, CYP1B1, GSK3B, IGF1R, MMP2, MMP9, PTGS2, RORC, SRC |
4.20254 |
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, DHFR, FABP3, FLT3, GSK3B, IGF1R, MMP2, PPARA, PTGS2, SRC |
4.17069 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, FABP3, FLT3, HMGCR, PPARA, PTGS2, RORC, SRC |
4.17069 |
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AURKB, AXL, CDC25B, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
4.16504 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, MMP9, SRC |
4.10076 |
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, APEX1, APP, AURKB, AXL, CDC25B, DHFR, FLT3, GSK3B, HMGCR, IGF1R, KDR, MET, PIM1, PTGS2, PTPN1, SRC, XDH |
3.99475 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, CYP1A1, CYP1B1, CYP3A4, FABP3, FABP4, FUT7, HMGCR, MET, PPARA, PTGS2 |
3.98365 |
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AXL, CA2, CA9, CYP1A1, CYP1B1, DHFR, GSK3B, IDO1, MMP2, MMP9, PPARA, PTGS2, PTPN1, SRC, TERT, TOP2A |
3.98348 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, APP, AXL, CYP1B1, FLT3, HMGCR, KDR, MET, PTGS2, PTPN1, SRC, XDH |
3.93485 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, APEX1, APP, CA2, CA9, FABP3, FLT3, GSK3B, IGF1R, MMP2, PPARA, PTGS2, SRC |
3.91162 |
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, DHFR, FABP3, FLT3, GSK3B, IGF1R, MMP2, PPARA, PTGS2, SRC |
3.89562 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, FLT3, GSK3B, IGF1R, KDR, PIM1, SRC |
3.89562 |
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, HMGCR |
3.78525 |
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, APEX1, APP, AURKB, AXL, CDC25B, DHFR, FLT3, GSK3B, HMGCR, IGF1R, KDR, MET, PIM1, PTGS2, PTPN1, SRC, XDH |
3.76155 |
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, PPARA |
3.76155 |
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, HMGCR, MMP2, MMP9, PTGS2, TERT |
3.75432 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, APP, AURKB, AXL, CA2, CA7, CYP19A1, CYP1B1, FLT3, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, TERT, XDH |
3.68949 |
[BP] GO:0044283 |
None
|
AKR1B1, ALOX5, CYP19A1, CYP1A1, CYP3A4, DHFR, HMGCR, IDO1, PTGS2 |
3.60456 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, APP, AURKB, AXL, CA2, CA7, CYP19A1, CYP1B1, FLT3, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, TERT, XDH |
3.60456 |
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, CDC25B, FLT3, HMGCR, IGF1R, KDR, MMP12, MMP2, MMP9, PIM1, PTGS2, TERT |
3.60221 |
[BP] GO:0014070 |
response to organic cyclic compound
|
APEX1, APP, CA2, CA9, CYP1A1, CYP1B1, DHFR, FLT3, PTGS2, RORC, SRC |
3.58922 |
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, APP, AURKB, AXL, CDC25B, CYP1A1, CYP3A4, DHFR, FLT3, FUT7, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC, TOP2A, XDH |
3.56691 |
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AURKB, AXL, CDC25B, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
3.56691 |
[BP] GO:0048869 |
cellular developmental process
|
ACHE, APP, AXL, CDC25B, CYP1A1, FABP4, FLT3, FUT7, GLO1, GSK3B, HMGCR, KDR, MET, MMP2, MMP9, PTGS2, RORC, SRC, TERT, TOP2A |
3.54662 |
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, APP, AURKB, AXL, CYP19A1, CYP1B1, DHFR, FABP4, FLT3, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP12, MMP2, MMP9, PPARA, PTGS2, PTPN1, SRC, TERT, XDH |
3.51757 |
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, CYP1B1, MMP9, PTGS2, SRC |
3.4308 |
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, GSK3B, MET, MMP9, PPARA, SRC, TERT |
3.4308 |
[BP] GO:1901989 |
None
|
APEX1, APP, CDC25B, CYP1A1, TERT |
3.36755 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
APEX1, APP, CYP1A1, CYP1B1, FLT3, PTGS2, RORC, SRC |
3.36551 |
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, APP, AURKB, CDC25B, DHFR, FABP3, FLT3, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
3.30656 |
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, APP, AURKB, CDC25B, FABP3, FLT3, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
3.24256 |
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, APEX1, APP, AXL, CA12, CA2, CA7, FABP3, FABP4, FLT3, MET, SRC, TERT |
3.22939 |
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, FLT3, IGF1R, KDR, MET, MMP2, MMP9, PTPN1, SRC |
3.22861 |
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, CYP1A1, MMP2, PPARA, PTGS2, SRC, TERT |
3.21009 |
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, DHFR, GSK3B, HMGCR, IGF1R, MET, PTGS2, PTPN1, TERT, XDH |
3.20539 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, APP, AURKB, AXL, CYP1B1, FLT3, HMGCR, IGF1R, KDR, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
3.16888 |
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, CYP1A1, MMP2, PPARA, PTGS2, SRC, TERT |
3.13974 |
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, CA2, CYP1A1, HMGCR, MMP2, PPARA, PTGS2, SRC, TERT |
3.13292 |
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1B1, CYP3A4, FABP3, FABP4 |
3.11595 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, MMP9, SRC |
3.10725 |
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, APP, AXL, CA2, CA7, CYP19A1, GSK3B, HMGCR, MMP12, MMP9, PPARA, PTGS2, PTPN1, SRC, TERT |
3.07323 |
[BP] GO:0006066 |
None
|
AKR1B1, AKR1B10, APP, CYP1B1, CYP3A4, DHFR, HMGCR |
3.06907 |
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, GSK3B, IGF1R, MMP2, PTGS2, SRC |
3.06199 |
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, PTGS2, SRC |
3.02204 |
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX5, APP, AXL, CYP19A1, CYP1B1, FABP4, HMGCR, IDO1, IGF1R, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, RORC, SRC |
3.02204 |
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1A1, CYP1B1, HMGCR, KDR, SRC |
3.02117 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4 |
2.98908 |
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3, PPARA |
2.98908 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.98262 |
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AURKB, DHFR, FABP4, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, XDH |
2.96494 |
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, CYP1A1, MMP2, PPARA, PTGS2, SRC, TERT |
2.9583 |
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, APP, AURKB, CDC25B, FLT3, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.9583 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.95728 |
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, SRC |
2.95728 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4 |
2.95728 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, CYP1A1, CYP1B1 |
2.91302 |
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, MMP9, SRC |
2.90601 |
[BP] GO:0033993 |
response to lipid
|
AXL, CA2, CA9, CYP1A1, FABP3, FLT3, IDO1, PTGS2, RORC, SRC |
2.90044 |
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, CYP19A1, GSK3B, HMGCR, IGF1R, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, SRC, TERT, XDH |
2.89727 |
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, GSK3B, HMGCR, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, TERT, XDH |
2.87486 |
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, GSK3B, IGF1R, MMP2, PTGS2, SRC |
2.87486 |
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, GSK3B, HMGCR, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, TERT, XDH |
2.86566 |
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, APP, CDC25B, FABP4, FLT3, HMGCR, IGF1R, KDR, MMP9, PPARA, PTGS2, PTPN1, SRC, XDH |
2.85047 |
[BP] GO:0030198 |
extracellular matrix organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.8392 |
[BP] GO:0043062 |
extracellular structure organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.83327 |
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, APP, CDC25B, FABP3, FABP4, FLT3, HMGCR, IGF1R, KDR, MMP9, PPARA, PTGS2, PTPN1, SRC, XDH |
2.83061 |
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, APP, CDC25B, FABP3, FLT3, HMGCR, KDR, MMP9, PTGS2, PTPN1, SRC, XDH |
2.83061 |
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, APP, CDC25B, FABP3, FLT3, HMGCR, KDR, MMP9, PTGS2, PTPN1, SRC, XDH |
2.83061 |
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
2.80363 |
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, APP, CDC25B, FABP3, FABP4, FLT3, HMGCR, IGF1R, KDR, MMP9, PPARA, PTGS2, PTPN1, SRC, XDH |
2.80363 |
[BP] GO:0033554 |
cellular response to stress
|
AKR1B1, APEX1, AXL, CA2, CA9, CYP1B1, DHFR, GSK3B, MMP9, PTGS2, PTPN1, SRC, TERT, TOP2A |
2.80363 |
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR |
2.78919 |
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, GSK3B, IGF1R, SRC |
2.78683 |
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
APP, AXL, CA2, CYP1B1, HMGCR, IDO1, KDR, MET, MMP12, MMP9, PIM1, PTGS2, SRC, TERT |
2.78683 |
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, PTGS2 |
2.78073 |
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, APEX1, APP, AURKB, CA9, CDC25B, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GLO1, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.78041 |
[BP] GO:0010038 |
response to metal ion
|
APP, CA2, CYP1A1, FABP4, MMP9, PTGS2, TERT |
2.78041 |
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, CDC25B, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC |
2.76371 |
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, DHFR, FABP3, KDR, MMP2, PTGS2, SRC |
2.76371 |
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, APP, AURKB, CDC25B, FLT3, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.76371 |
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, PPARA, PTGS2, SRC |
2.76371 |
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AURKB, CYP19A1, CYP1A1, CYP1B1, CYP3A4, FABP3, FABP4, FUT7, GSK3B, IDO1, XDH |
2.74904 |
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, APP, AURKB, CDC25B, CYP1B1, DHFR, FABP4, FLT3, GSK3B, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC, TERT, XDH |
2.74728 |
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1B1, CYP3A4, HMGCR |
2.74564 |
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC |
2.74564 |
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, APP, CDC25B, FLT3, HMGCR, KDR, MMP9, PTGS2, PTPN1, SRC, XDH |
2.74564 |
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, APP, AURKB, CA9, CDC25B, CYP1B1, DHFR, FABP3, FABP4, FLT3, GLO1, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.74564 |
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
2.74537 |
[BP] GO:0043065 |
positive regulation of apoptotic process
|
CYP1B1, GSK3B, HMGCR, IDO1, MMP9, PTGS2, SRC, TOP2A, XDH |
2.74002 |
[BP] GO:0043068 |
positive regulation of programmed cell death
|
CYP1B1, GSK3B, HMGCR, IDO1, MMP9, PTGS2, SRC, TOP2A, XDH |
2.71011 |
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1 |
2.71011 |
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, APP, AURKB, CDC25B, DHFR, FABP4, FLT3, GSK3B, HMGCR, IGF1R, MMP9, PTGS2, PTPN1, SRC, TERT, XDH |
2.69948 |
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, FABP4, HMGCR, IDO1, KDR, MET, MMP12, PPARA, PTGS2 |
2.69399 |
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, APP, AXL, CA2, CYP19A1, GSK3B, MMP12, PTGS2, SRC, TERT |
2.69399 |
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, FABP4, IDO1, MMP12, MMP2, PPARA, PTGS2, PTPN1, SRC |
2.67895 |
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
2.67895 |
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, CA2, CA7, HMGCR, KDR, PTGS2, SRC |
2.6567 |
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, APP, CDC25B, FABP4, FLT3, HMGCR, IGF1R, KDR, MMP9, PTGS2, PTPN1, SRC, XDH |
2.6567 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.6567 |
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.6567 |
[BP] GO:0032787 |
None
|
ALOX5, CYP1A1, CYP1B1, FABP3, GLO1, IDO1, PPARA, PTGS2 |
2.64164 |
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.63118 |
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, APP, AURKB, CA9, CDC25B, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GLO1, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.62287 |
[BP] GO:0007568 |
aging
|
APEX1, AURKB, CYP1A1, HMGCR, PTGS2, TERT |
2.61692 |
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, APP, CDC25B, FLT3, HMGCR, KDR, MMP9, PTGS2, PTPN1, SRC, XDH |
2.61692 |
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
MMP2, MMP9, TERT |
2.60866 |
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, IGF1R, KDR, MET, MMP9, PTGS2, SRC, TERT |
2.59839 |
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, GSK3B, HMGCR, MMP12, PTGS2, PTPN1, SRC |
2.59588 |
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, APEX1, APP, AURKB, CA9, CDC25B, CYP1B1, DHFR, FABP3, FABP4, FLT3, GLO1, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.57292 |
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, APP, AURKB, DHFR, FABP4, GSK3B, HMGCR, IGF1R, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, XDH |
2.52996 |
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, FABP4, FLT3, GSK3B, HMGCR, IGF1R, PTPN1, SRC |
2.52996 |
[BP] GO:1901992 |
positive regulation of mitotic cell cycle phase transition
|
APEX1, APP, CYP1A1, TERT |
2.52996 |
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AURKB, AXL, CA1, CA2, CA7, CA9, CDC25B, CYP19A1, CYP1A1, CYP1B1, DHFR, FABP3, FABP4, FLT3, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.52786 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, APEX1, CA2, CA9, FABP3, FLT3, PPARA, PTGS2, SRC |
2.52786 |
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, TERT |
2.52786 |
[BP] GO:0010942 |
positive regulation of cell death
|
CYP1B1, GSK3B, HMGCR, IDO1, MMP9, PTGS2, SRC, TOP2A, XDH |
2.51994 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, HMGCR |
2.49344 |
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, APP, FLT3, HMGCR, KDR, PTPN1, SRC, XDH |
2.48358 |
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AURKB, DHFR, FABP4, GSK3B, HMGCR, IGF1R, KDR, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, XDH |
2.48178 |
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, SRC, TERT |
2.47842 |
[BP] GO:0044243 |
multicellular organismal catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.47842 |
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, FLT3, IGF1R, KDR, MET, MMP2, MMP9, PTPN1, SRC |
2.46723 |
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
HMGCR, IGF1R, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
2.4587 |
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, FLT3, GSK3B, IGF1R, MMP2, PTGS2, SRC |
2.43087 |
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX5, CYP1A1, CYP1B1, DHFR, FABP3, GLO1, IDO1, PIM1, PPARA, PTGS2 |
2.43087 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
CA2, CA7 |
2.42323 |
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, CYP1A1, CYP1B1, CYP3A4, DHFR, IDO1 |
2.40568 |
[BP] GO:1904646 |
cellular response to amyloid-beta
|
APP, GSK3B, IGF1R |
2.39297 |
[BP] GO:0002521 |
leukocyte differentiation
|
AXL, FLT3, FUT7, GLO1, MMP9, RORC |
2.38523 |
[BP] GO:0022617 |
extracellular matrix disassembly
|
MMP1, MMP12, MMP2, MMP9 |
2.36911 |
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, CYP1B1, FABP3, IDO1, PTGS2, TERT, XDH |
2.35053 |
[BP] GO:0032963 |
collagen metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.33058 |
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, DHFR, HMGCR |
2.32883 |
[BP] GO:0051099 |
positive regulation of binding
|
APP, GSK3B, MET, MMP9, TERT |
2.31816 |
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, IDO1, PTGS2 |
2.29517 |
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, APP, FLT3, HMGCR, IGF1R, KDR, PTPN1, SRC, XDH |
2.28979 |
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, TERT |
2.28429 |
[BP] GO:1901661 |
None
|
AKR1B1, AKR1B10, HMGCR |
2.27616 |
[BP] GO:1904645 |
response to amyloid-beta
|
APP, GSK3B, IGF1R |
2.27616 |
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, APP, AURKB, AXL, CYP1B1, FLT3, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, TERT, XDH |
2.27616 |
[BP] GO:0032092 |
positive regulation of protein binding
|
APP, GSK3B, MMP9, TERT |
2.2668 |
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, APP, AURKB, CA9, CDC25B, CYP1B1, DHFR, FABP4, FLT3, GLO1, GSK3B, HMGCR, IGF1R, KDR, MET, MMP12, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.2668 |
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AURKB, AXL, CA1, CA12, CA2, CA7, CA9, CDC25B, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, FABP3, FABP4, FLT3, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.25282 |
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.25282 |
[BP] GO:0048511 |
rhythmic process
|
AXL, GSK3B, PPARA, RORC, SRC, TOP2A |
2.21788 |
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7 |
2.20794 |
[BP] GO:0046165 |
None
|
AKR1B1, CYP3A4, DHFR, HMGCR |
2.20428 |
[BP] GO:0030154 |
cell differentiation
|
AXL, CYP1A1, FABP4, FLT3, FUT7, GLO1, GSK3B, HMGCR, KDR, MMP2, MMP9, PTGS2, RORC, TOP2A |
2.19571 |
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, APP, AXL, CA2, CYP1B1, GSK3B, HMGCR, IDO1, KDR, MET, MMP12, MMP9, PIM1, PTGS2, SRC, TERT, XDH |
2.17692 |
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, CYP1A1, DHFR, PPARA |
2.16071 |
[BP] GO:0022414 |
reproductive process
|
AKR1B1, APP, AXL, CDC25B, CYP19A1, CYP1A1, IDO1, MMP2, MMP9, PTGS2, SRC, TOP2A |
2.15756 |
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1B1, FABP3, PPARA, PTGS2 |
2.13391 |
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX5, CYP1A1, CYP1B1, DHFR, FABP3, GLO1, IDO1, PIM1, PPARA, PTGS2 |
2.13363 |
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, CDC25B, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC |
2.1283 |
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ACHE, AKR1B1, AKR1B10, APEX1, APP, AURKB, AXL, CDC25B, CYP1A1, CYP1B1, CYP3A4, DHFR, FLT3, FUT7, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.11456 |
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
MMP9, PTGS2, PTPN1, SRC |
2.11441 |
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, CA2, CA7, PTGS2 |
2.10762 |
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, CA2, CA7, PTGS2 |
2.10762 |
[BP] GO:0002933 |
lipid hydroxylation
|
CYP1A1, CYP3A4 |
2.10762 |
[BP] GO:0010906 |
None
|
GSK3B, PPARA, RORC, SRC |
2.1076 |
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1B1, PTGS2 |
2.09188 |
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX5, CYP1A1, CYP1B1, DHFR, FABP3, GLO1, IDO1, PIM1, PPARA, PTGS2 |
2.09161 |
[BP] GO:1900087 |
None
|
APEX1, CYP1A1, TERT |
2.09161 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, APP, AXL, CA2, CYP19A1, CYP1A1, CYP1B1, DHFR, FLT3, GSK3B, KDR, MMP9, PIM1, PPARA, PTGS2, RORC, SRC |
2.0834 |
[BP] GO:0042752 |
None
|
ADORA1, PPARA, RORC, TOP2A |
2.0834 |
[BP] GO:0032091 |
negative regulation of protein binding
|
AURKB, GSK3B, MET, PPARA |
2.0834 |
[BP] GO:0034405 |
response to fluid shear stress
|
CA2, PTGS2, SRC |
2.06391 |
[BP] GO:0009968 |
negative regulation of signal transduction
|
GSK3B, HMGCR, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, SRC, TERT, XDH |
2.05435 |
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, FABP4, FLT3, HMGCR, IGF1R, PTPN1, SRC |
2.04638 |
[BP] GO:0007566 |
embryo implantation
|
MMP2, MMP9, PTGS2 |
2.0346 |
[BP] GO:0097756 |
None
|
ADORA1, HMGCR, PTGS2 |
2.0074 |
[BP] GO:1904705 |
regulation of vascular smooth muscle cell proliferation
|
MMP2, MMP9, TERT |
2.0074 |
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX5, CYP1A1, CYP1B1, PTGS2 |
2.0004 |
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, CA4, CYP19A1, FLT3, HMGCR, KDR, PTGS2, PTPN1, XDH |
2.7521 |
[CC] GO:0097443 |
sorting endosome
|
KDR, PTPN1 |
2.10762 |
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AURKB, CA1, CA2, CA4, CA7, CDC25B, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, HMGCR, IDO1, KDR, MMP2, MMP9, PIM1, PTGS2, PTPN1, SRC, TERT, TOP2A, XDH |
2.0074 |
[CC] GO:0043227 |
membrane-bounded organelle
|
ACHE, ADORA1, AKR1B1, AKR1B10, APEX1, APP, AURKB, AXL, CA1, CA2, CA4, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, FABP3, FABP4, FLT3, FUT7, GLO1, GSK3B, HMGCR, IGF1R, KDR, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.0074 |
[CC] GO:0043231 |
intracellular membrane-bounded organelle
|
ACHE, ADORA1, AKR1B1, AKR1B10, APEX1, APP, AURKB, CA4, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, FABP4, FLT3, FUT7, GLO1, GSK3B, HMGCR, IGF1R, KDR, MMP12, MMP2, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
1.92021 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1B1, CYP3A4, GLO1, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTPN1, RORC, XDH |
10.9265 |
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDC25B, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, FLT3, FUT7, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PTGS2, PTPN1, SRC, TERT, TOP2A, XDH |
10.9265 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
10.8368 |
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX5, APEX1, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, FABP3, FABP4, FLT3, GLO1, GSK3B, HMGCR, IDO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
10.6427 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.75004 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.17122 |
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, GLO1 |
6.35311 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1B1, CYP3A4, GLO1, IDO1, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, TERT, TOP2A, XDH |
6.26916 |
[MF] GO:0046872 |
metal ion binding
|
ALOX5, APEX1, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1B1, CYP3A4, GLO1, IDO1, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, TERT, TOP2A, XDH |
5.78746 |
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA7, CA9, GLO1, MMP1, MMP12, MMP2, MMP9, PPARA, PTPN1, RORC |
5.54434 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX5, APEX1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, HMGCR, IDO1, PTGS2, XDH |
5.14928 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1B1, CYP3A4, IDO1, PTGS2, SRC |
4.9051 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1B1, CYP3A4, IDO1, PTGS2, SRC |
4.73021 |
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, HMGCR, IDO1, PTGS2, SRC, XDH |
4.16759 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1B1, CYP3A4 |
4.06112 |
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, PPARA, SRC, TOP2A |
4.035 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.91767 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1B1, CYP3A4 |
3.89562 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.48603 |
[MF] GO:0005506 |
iron ion binding
|
ALOX5, CYP19A1, CYP1A1, CYP1B1, CYP3A4, XDH |
3.26843 |
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, FLT3, IGF1R, KDR, MMP12, MMP9, PPARA, PTPN1, SRC |
3.26843 |
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, FLT3, IGF1R, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SRC |
3.1924 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1B1, CYP3A4 |
3.07323 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
3.02819 |
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.6567 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC |
2.5451 |
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX5, IDO1, PTGS2 |
2.43087 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1B1, CYP3A4, PTGS2 |
2.40568 |
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX5, IDO1, PTGS2 |
2.39297 |
[MF] GO:0101020 |
estrogen 16-alpha-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.24606 |
[MF] GO:0005158 |
None
|
IGF1R, PTPN1, SRC |
2.24606 |
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP3A4 |
2.13939 |
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1B1, CYP3A4 |
2.11441 |
[MF] GO:0004064 |
arylesterase activity
|
CA1, CA2 |
2.10762 |
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, FLT3, GSK3B, IGF1R, KDR, MET, PIM1, SRC |
2.06391 |