Prescription Description
| Prescription ID | TCMF6829 |
| Pinyin Name | Zhi Dai Pian |
| Chinese Name | 治带片 |
| English Name | Zhi Dai Tablets |
| Function Description | 带下病 |
| Indications | Leukorrhea disorder |
| Disease ICD-11 Category |
SC20 [Leukorrhea disorder (TM1), 带下病 (TM1)
]; |
| Human Tissues Associated with Indication | Uterus |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1532 | Patrinia rupestris | 墓头回 | TCMH1532 | GBVF2379-11 |
| TCMH1215 | Sophora flavescens | 苦参 | TCMH1215 | ITSAM449-14 |
| TCMH1133 | Rosa laevigata | 金樱子 | TCMH1133 | ITSAJ4477-14 |
| TCMH2624 | Anemarrhena asphodeloides | 知母 | TCMH2624 | GBVA3255-11, GBVU1201-13 |
| TCMH211 | Atractylodes lancea | 苍术 | TCMH211 | ITSAN4439-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT100 | TTR | Transthyretin | Unclassified | P02766 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT102 | ACP1 | Low molecular weight phosphotyrosine protein phosphatase | Hydrolase | P24666 |
| TCMT103 | PTPRF | Receptor-type tyrosine-protein phosphatase F (LAR) | Hydrolase | P10586 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
Showing 1 to 10 of 92 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
| TCMT1208 | Escherichia coli K12 |
| TCMT1209 | Staphylococcus haemolyticus |
| TCMT1210 | Streptococcus sobrinus |
| TCMT1211 | Fusobacterium nucleatum |
Showing 1 to 10 of 52 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, AKR1C3, AXL, CYP1B1, EGFR, SRC | 2.96083 |
| [BP] GO:0001505 | regulation of neurotransmitter levels | ACHE, CYP1B1, EGFR, INSR, MAOB, SMAD3 | 2.19832 |
| [BP] GO:0001523 | None | AKR1B10, AKR1C3, CYP1A1, CYP1B1 | 2.07985 |
| [BP] GO:0001666 | response to hypoxia | ADORA1, CYP1A1, PPARA, SMAD3, SRC, TEK | 2.17251 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ADORA1, CDC25B, DUSP3, EGFR, FABP4, FLT3, IGF1R, INSR, KDR, MIF, PDE5A, PTPN1, SRC, TEK, XDH | 3.14077 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | ADORA1, CDC25B, EGFR, FLT3, INSR, KDR, MIF, PDE5A, PTPN1, SRC, TEK, XDH | 2.87671 |
| [BP] GO:0002009 | morphogenesis of an epithelium | CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC | 2.81539 |
| [BP] GO:0002682 | regulation of immune system process | ADORA1, AXL, CA2, CYP19A1, DUSP3, ESR1, ESRRA, HCAR2, HSPA1A, MIF, MMP12, PDE5A, PTPN1, SMAD3, SRC | 2.73376 |
| [BP] GO:0002683 | negative regulation of immune system process | ADORA1, AXL, CYP19A1, DUSP3, MIF, MMP12, PDE5A | 2.01105 |
| [BP] GO:0002793 | None | ACHE, ADORA1, EGFR, HCAR2, MIF, MMP12, SRC | 3.0373 |
Showing 1 to 10 of 377 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| Acute myeloid leukemia_Homo sapiens_hsa05221 | FLT3, PIM1 | 1.4242 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, SMAD3, CSNK2A1, SRC, INSR, MET, EGFR, IGF1R | 8.8576 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA | 0.6295 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | SMAD3, PIM1 | 1.1055 |
| Alcoholism_Homo sapiens_hsa05034 | MAOB | 0.3881 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | INSR | 0.7765 |
| Amphetamine addiction_Homo sapiens_hsa05031 | MAOB | 0.6428 |
| AMPK signaling pathway_Homo sapiens_hsa04152 | INSR, IGF1R | 0.9991 |
| Antigen processing and presentation_Homo sapiens_hsa04612 | HSPA1A | 0.608 |
| Arachidonic acid metabolism_Homo sapiens_hsa00590 | ALOX5, AKR1C3 | 1.3844 |
Showing 1 to 10 of 142 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples