GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, HSD17B1, HSD17B2, MET, PPARA |
7.70083 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, APP, AR, AXL, CA2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, HSD17B2, IGF1R, KDR, MMP2, NR3C1, PPARA, RORC, SRC, TYR |
5.7259 |
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, AR, AURKB, AXL, CA12, CA2, CA4, CA7, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPRS, RORC, SRC, TNKS, TNKS2, TYR, XDH |
5.7259 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, APP, AR, AXL, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, HSD17B2, IGF1R, MMP2, MMP9, NR3C1, PPARA, RORC, SRC, TYR |
5.7259 |
[BP] GO:0042221 |
response to chemical
|
ABCB1, AKR1B1, ALOX15, APP, AR, AXL, CA2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, HSD17B2, IGF1R, KDR, MMP2, MMP9, NR3C1, PPARA, RORC, SRC, TYR |
5.7259 |
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, KDR, MET, MMP12, MMP9, SRC, TNKS, TNKS2, XDH |
5.7259 |
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, KDR, MET, MMP12, MMP9, SRC, TNKS, TNKS2, XDH |
5.7259 |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, APP, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, FABP4, KDR, MMP9, SRC |
5.67633 |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, APP, CA12, CA2, CA4, CA7, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FUT7, PIM1, PPARA, TYR, XDH |
5.51371 |
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA12, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, FABP3, FABP4, FLT3, HSD17B1, HSD17B2, KDR, MET, PPARA, SRC, TNKS, TNKS2, XDH |
5.44834 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, CYP1A1, CYP1A2, CYP1B1, TYR |
5.36021 |
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, FABP3, FABP4, FLT3, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIM1, PPARA, RORC, SRC, TNKS, TNKS2, XDH |
5.07087 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, FABP3, FLT3, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIM1, PPARA, RORC, SRC, TNKS, TNKS2, XDH |
5.04322 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD17B1, HSD17B2 |
4.94613 |
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, FUT7, HSD17B2, KDR, MET, MMP2, MMP9, PGR, PIM1, PPARA, PTPRS, RORC, SRC, TNKS2, TYR |
4.84677 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, AR, AURKB, AXL, CA12, CA2, CA4, CA7, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP2, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPRS, RORC, SRC, TNKS, TNKS2, TYR, XDH |
4.76597 |
[BP] GO:0033993 |
response to lipid
|
AR, AXL, CA2, CSNK2A1, CYP1A1, CYP1A2, FABP3, FLT3, HSD17B2, NR3C1, RORC, SRC, TYR |
4.76551 |
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
4.51958 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, AR, CSNK2A1, CYP1B1, FABP3, FLT3, IGF1R, KDR, MMP12, MMP2, MMP9, PGR, PIM1, SRC, XDH |
4.46879 |
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, AR, AURKB, AXL, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPRS, RORC, SRC, TNKS, TNKS2, TYR, XDH |
4.33716 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, APP, AR, AXL, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, IGF1R, KDR, MMP2, MMP9, NR3C1, RORC, SRC |
4.31991 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, MET, PPARA |
4.28467 |
[BP] GO:0015701 |
bicarbonate transport
|
CA12, CA14, CA2, CA4, CA7 |
4.25219 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, CSNK2A1, CYP1B1, FLT3, KDR, MET, MMP12, MMP9, SRC, TNKS, TNKS2, XDH |
4.25219 |
[BP] GO:0048513 |
animal organ development
|
ACHE, AR, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, FLT3, HSD17B2, KDR, PPARA, PTPRS, SRC, TYR |
4.06723 |
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, AR, AXL, CYP19A1, CYP1A2, CYP1B1, FABP4, HSD17B2, IGF1R, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, RORC, SRC, TNKS2, TYR |
4.06723 |
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1 |
4.03472 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, HSD17B2, KDR, MMP9, PGR, PIM1, PPARA, PTPRS, RORC, SRC, TYR |
4.03041 |
[BP] GO:0014070 |
response to organic cyclic compound
|
APP, AR, CA2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FLT3, NR3C1, RORC, SRC, TYR |
3.99325 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, APP, AR, AXL, CYP1A1, CYP1B1, FABP4, FLT3, IGF1R, KDR, MMP2, NR3C1, RORC, SRC |
3.99325 |
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
3.9811 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD17B1, HSD17B2, TYR, XDH |
3.93506 |
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, MMP1, MMP12, MMP2, MMP9, SRC, XDH |
3.93506 |
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1 |
3.93506 |
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1 |
3.93506 |
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, NR3C1, PGR, PIM1, PPARA, RORC, SRC |
3.90091 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1, HSD17B2 |
3.86726 |
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, AR, AURKB, AXL, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPRS, RORC, SRC, TNKS, TNKS2, TYR, XDH |
3.81251 |
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.80512 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1, HSD17B2 |
3.78042 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, IGF1R, KDR, MET, MMP12, MMP9, PTPRS, SRC, TNKS, TNKS2, XDH |
3.76187 |
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, IGF1R, KDR, MET, MMP9, PIM1, PPARA, SRC |
3.72132 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, FLT3, IGF1R, KDR, MET, MMP12, MMP9, PTPRS, SRC, TNKS, TNKS2, XDH |
3.69323 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, FLT3, IGF1R, KDR, PIM1, SRC |
3.65919 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, CSNK2A1, CYP1B1, FABP4, FLT3, KDR, MET, MMP12, MMP2, MMP9, SRC, TNKS, TNKS2, XDH |
3.65919 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, APP, AR, CA2, CSNK2A1, CYP1A2, FABP3, FLT3, IGF1R, MMP2, NR3C1, PPARA, SRC |
3.60385 |
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, FABP3, PPARA |
3.59514 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, IGF1R, KDR, MET, MMP9, PIM1, SRC |
3.37011 |
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, FABP3, FABP4, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIM1, PPARA, PTPRS, RORC, SRC, TNKS, TNKS2, XDH |
3.34207 |
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, IGF1R, KDR, MET, MMP9, PIM1, PPARA, SRC, XDH |
3.30256 |
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7 |
3.2537 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.2537 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA12, CA2, CA4, CA7 |
3.21238 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, FABP3, FABP4, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PIM1, PPARA, PTPRS, RORC, SRC, TNKS, TNKS2, XDH |
3.197 |
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APP, AR, AXL, CYP1B1, IGF1R, MMP2, MMP9, NR3C1, RORC, SRC |
3.17612 |
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP12, MMP9, PPARA, SRC |
3.14529 |
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1 |
3.14229 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
APP, AR, CYP1A1, CYP1B1, FLT3, NR3C1, RORC, SRC |
3.14162 |
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, NR3C1, NR3C2, PGR, PPARA, RORC |
3.07896 |
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, IGF1R, KDR, MET, MMP9, PIM1, SRC, XDH |
3.06311 |
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, FABP4, FLT3, IGF1R, KDR, MET, MMP12, MMP2, MMP9, PPARA, PTPRS, SRC, TNKS, TNKS2, XDH |
3.04601 |
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.95302 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AXL, CYP1B1, FLT3, KDR, MET, SRC, XDH |
2.95302 |
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, AR, AURKB, CYP1A1, FLT3, MET, PIM1, SRC, TYR |
2.9309 |
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CSNK2A1, CYP1B1, FABP4, IGF1R, MET, MMP9, PIM1, PPARA, SRC, TNKS |
2.9309 |
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, IGF1R, KDR, MET, MMP1, MMP9, SRC, TNKS, TNKS2 |
2.91835 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, AR, CA2, CSNK2A1, CYP1A2, FABP3, FLT3, NR3C1, PPARA, SRC |
2.91835 |
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4 |
2.91835 |
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1 |
2.89733 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, IGF1R, KDR, MET, MMP9, SRC, XDH |
2.85172 |
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, HSD17B2, IGF1R, KDR, MMP12, MMP2, MMP9, NR3C1, PPARA, RORC, SRC, TYR |
2.84485 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.79051 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, IGF1R, KDR, MMP9, PIM1, SRC |
2.77553 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AXL, CYP1B1, MMP9, SRC |
2.76971 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.76384 |
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX15, APP, CYP19A1, CYP1A1, CYP1B1, TYR |
2.73134 |
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA12, CA14, CA2, CA4, CA7, FABP3, PPARA |
2.70519 |
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.68938 |
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.67574 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, APP, AR, AURKB, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, IGF1R, KDR, MMP2, MMP9, NR3C1, RORC, SRC |
2.65747 |
[BP] GO:0030198 |
extracellular matrix organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.61792 |
[BP] GO:0043062 |
extracellular structure organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.61284 |
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, NR3C1, NR3C2, PGR, PPARA, RORC |
2.60363 |
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, MET, MMP9, PPARA, SRC |
2.60363 |
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, CSNK2A1, FLT3, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PPARA, RORC, SRC, TNKS, TNKS2, XDH |
2.59257 |
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, IGF1R, KDR, MMP9, PIM1, SRC, XDH |
2.54686 |
[BP] GO:0010038 |
response to metal ion
|
ALOX15, APP, CA2, CYP1A1, CYP1A2, FABP4, MMP9 |
2.54686 |
[BP] GO:1904356 |
regulation of telomere maintenance via telomere lengthening
|
AURKB, SRC, TNKS, TNKS2 |
2.51722 |
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD17B1, HSD17B2 |
2.49233 |
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, CSNK2A1, FLT3, IGF1R, KDR, MET, PIM1, SRC, TNKS |
2.47905 |
[BP] GO:0060748 |
None
|
AR, PGR |
2.46518 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.46518 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.45034 |
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, SRC |
2.45034 |
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, CSNK2A1, FABP3, FLT3, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PPARA, RORC, SRC, TNKS, TNKS2, XDH |
2.45034 |
[BP] GO:2000573 |
positive regulation of DNA biosynthetic process
|
AURKB, SRC, TNKS, TNKS2 |
2.43824 |
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.41496 |
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, FABP3, FLT3, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PPARA, RORC, SRC, TNKS, TNKS2, XDH |
2.39788 |
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, CA2, CA7, KDR, SRC, TNKS, TNKS2 |
2.39569 |
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, MET, MMP9, PPARA, SRC, TNKS |
2.39456 |
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, FABP3, PPARA |
2.37736 |
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, CSNK2A1, FLT3, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PPARA, RORC, SRC, TNKS, TNKS2, XDH |
2.37736 |
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AR, AURKB, FABP3, IGF1R, KDR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SRC, TNKS, TNKS2 |
2.36734 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.36734 |
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, APP, AR, AURKB, AXL, CSNK2A1, CYP1B1, FLT3, IGF1R, KDR, MET, MMP12, MMP9, PTPRS, SRC, TNKS, TNKS2, XDH |
2.33886 |
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.32299 |
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, FLT3, IGF1R, KDR, MET, MMP2, MMP9, SRC |
2.27915 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, FABP3, FLT3, PPARA, RORC, SRC |
2.27633 |
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, SRC |
2.27273 |
[BP] GO:0044243 |
multicellular organismal catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.27062 |
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, FABP4, MMP9 |
2.26269 |
[BP] GO:0071383 |
None
|
AR, FLT3, NR3C1, SRC |
2.25336 |
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.25299 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
CA2, CA7 |
2.25299 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.25299 |
[BP] GO:1904353 |
regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.25132 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, HSD17B1, HSD17B2 |
2.25132 |
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, FLT3, KDR, SRC, XDH |
2.24217 |
[BP] GO:1904357 |
None
|
SRC, TNKS, TNKS2 |
2.20766 |
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AR, AURKB, IGF1R, KDR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SRC, TNKS, TNKS2 |
2.19611 |
[BP] GO:0032204 |
None
|
AURKB, SRC, TNKS, TNKS2 |
2.19525 |
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, NR3C1, PGR, SRC |
2.19525 |
[BP] GO:0022617 |
extracellular matrix disassembly
|
MMP1, MMP12, MMP2, MMP9 |
2.17629 |
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APP, AR, AURKB, CSNK2A1, FABP4, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PPARA, RORC, SRC, TNKS, TNKS2, XDH |
2.16762 |
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, FABP3, PIM1, PPARA, TYR |
2.16514 |
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, APP, CYP19A1, FABP4, IGF1R, MET, MMP12, MMP2, PPARA, PTPRS, SRC, XDH |
2.14782 |
[BP] GO:1901655 |
None
|
AKR1B1, AR, NR3C1, SRC |
2.14733 |
[BP] GO:0032963 |
collagen metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.14733 |
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, ADORA1, CA2, CA7 |
2.12911 |
[BP] GO:0006820 |
anion transport
|
ABCB1, CA12, CA14, CA2, CA4, CA7, FABP3, PPARA |
2.08115 |
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AR, CSNK2A1, FLT3, IGF1R, KDR, MMP12, MMP2, MMP9, PIM1 |
2.07275 |
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.05729 |
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, APP, AURKB, AXL, CSNK2A1, FLT3, IGF1R, KDR, MET, PIM1, PTPRS, SRC, TNKS, XDH |
2.05729 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, SRC |
2.05729 |
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX15, CSNK2A1, CYP19A1, CYP1A1, HSD17B1, HSD17B2 |
2.05253 |
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APP, CYP19A1, CYP1B1, IGF1R, KDR, MET, MMP9, SRC |
2.05167 |
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, FLT3, IGF1R, KDR, SRC, XDH |
2.04699 |
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7 |
2.04125 |
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, FABP4, MMP9 |
2.03717 |
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, AXL, CYP1B1, KDR, NR3C1, SRC |
2.0255 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AXL, CYP1B1, MMP9, SRC |
2.01838 |
[BP] GO:0048511 |
rhythmic process
|
AXL, CSNK2A1, PGR, PPARA, RORC, SRC |
2.01351 |
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, APP, AR, AURKB, CA2, CA4, CA7, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, HSD17B1, HSD17B2, KDR, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTPRS, SRC, TNKS, TNKS2, TYR, XDH |
1.78064 |
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP |
1.75794 |
[CC] GO:0016020 |
membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, ALOX5, APP, AR, AXL, CA12, CA14, CA2, CA4, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, FUT7, HSD17B2, IGF1R, KDR, MET, MMP2, NR3C2, PGR, PIM1, PTPRS, SRC, TNKS, TNKS2, TYR |
1.73356 |
[CC] GO:0099055 |
None
|
ADORA1, PTPRS |
1.68762 |
[CC] GO:0099699 |
None
|
ADORA1, PTPRS |
1.68762 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, APP, AR, CA12, CA2, CA4, CA7, CYP19A1, CYP1A1, CYP1A2, CYP1B1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, RORC, TNKS, TYR, XDH |
13.9382 |
[MF] GO:0043167 |
ion binding
|
ABCB1, ACHE, ALOX15, ALOX5, APP, AR, AURKB, AXL, CA12, CA14, CA2, CA4, CA7, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, HSD17B1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPRS, RORC, SRC, TNKS, TNKS2, TUBB3, TYR, XDH |
10.0991 |
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, AURKB, AXL, CA12, CA14, CA2, CA4, CA7, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, FUT7, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PTPRS, SRC, TNKS, TNKS2, TUBB3, TYR, XDH |
7.80077 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA12, CA14, CA2, CA4, CA7 |
5.96157 |
[MF] GO:0008270 |
zinc ion binding
|
AR, CA12, CA2, CA4, CA7, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PPARA, RORC, TNKS |
5.7259 |
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, NR3C1, NR3C2, PGR, PPARA, RORC |
5.04322 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, APP, AR, AURKB, CA12, CA14, CA2, CA4, CA7, CYP19A1, CYP1A1, CYP1A2, CYP1B1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, RORC, TNKS, TNKS2, TYR, XDH |
4.79996 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD17B1, HSD17B2, TYR, XDH |
4.7267 |
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, APP, AR, AURKB, CA12, CA14, CA2, CA4, CA7, CYP19A1, CYP1A1, CYP1A2, CYP1B1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, RORC, TNKS, TNKS2, TYR, XDH |
4.41875 |
[MF] GO:0005496 |
steroid binding
|
AR, HSD17B1, NR3C1, NR3C2, PGR, RORC |
4.27355 |
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, XDH |
4.05288 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA12, CA14, CA2, CA4, CA7 |
3.90383 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.86646 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.71615 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.69834 |
[MF] GO:0008289 |
lipid binding
|
ALOX15, AR, AXL, FABP3, FABP4, HSD17B1, NR3C1, NR3C2, PGR, PPARA, RORC |
3.56819 |
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, CBR1, HSD17B1, HSD17B2, XDH |
3.39299 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
CA12, CA14, CA2, CA4, CA7 |
3.37011 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.2789 |
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, HSD17B1, IGF1R, NR3C1 |
3.15707 |
[MF] GO:0008144 |
drug binding
|
ABCB1, ACHE, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, IGF1R, KDR, MET, PIM1, PPARA, SRC |
3.07896 |
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, TYR |
2.96224 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
2.91835 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.84485 |
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, PGR, PPARA, RORC |
2.79641 |
[MF] GO:0004879 |
nuclear receptor activity
|
AR, PGR, PPARA, RORC |
2.79641 |
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HSD17B1, HSD17B2 |
2.60363 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, SRC |
2.47905 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, SRC |
2.37047 |
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AR, AXL, FLT3, IGF1R, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC |
2.35793 |
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, CSNK2A1, FLT3, IGF1R, KDR, MMP12, MMP9, PIM1, PPARA, SRC |
2.32801 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, IGF1R, KDR, MET, PIM1, SRC |
2.27633 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, TYR |
2.19611 |
[MF] GO:0043168 |
anion binding
|
ABCB1, ALOX15, APP, AURKB, AXL, CSNK2A1, FABP3, FABP4, FLT3, HSD17B1, IGF1R, KDR, MET, PIM1, PTPRS, SRC, TUBB3, XDH |
2.05729 |
[MF] GO:0051879 |
Hsp90 protein binding
|
CSNK2A1, KDR, NR3C1 |
2.04125 |