GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, TYR, XDH |
9.27485 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AR, AXL, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, FABP3, HSD17B2, IGF1R, MMP2, MMP9, NR3C1, PPARA, RORC, SRC, TYR |
8.22574 |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD2, FABP3, FABP4, FUT7, HSD17B1, HSD17B2, MET, PPARA |
7.92177 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, FABP3, FABP4, FLT3, FUT7, GLO1, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP2, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, TYR, XDH |
7.27412 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, APEX1, APP, AR, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, FABP3, FABP4, FLT3, HSD17B2, IGF1R, KDR, MMP2, NR3C1, PPARA, RORC, SRC, TYR |
7.27412 |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, APEX1, APP, AXL, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, FABP4, KDR, MMP9, SRC, TERT |
7.27412 |
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.23979 |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FUT7, GLO1, PIM1, PPARA, TYR, XDH |
7.01101 |
[BP] GO:0042221 |
response to chemical
|
AKR1B1, APEX1, APP, AR, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, FABP3, FABP4, FLT3, HSD17B2, IGF1R, KDR, MMP2, MMP9, NR3C1, PPARA, RORC, SRC, TERT, TYR |
6.97829 |
[BP] GO:0014070 |
response to organic cyclic compound
|
APEX1, APP, AR, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, FLT3, NR3C1, RORC, SRC, TYR |
6.87538 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, APEX1, APP, AR, AURKB, AXL, CA2, CA7, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, F3, FABP3, FLT3, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
6.77808 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, APP, AR, CDC25B, CSNK2A1, CYP1B1, DRD2, F3, FABP3, FLT3, IGF1R, KDR, MMP12, MMP2, MMP9, PGR, PIM1, SRC, TERT, XDH |
6.67467 |
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, CSNK2A1, CYP1B1, F3, FLT3, GLO1, IGF1R, KDR, MET, MMP9, PIM1, PPARA, PTPN1, SRC, TERT, TOP2A, XDH |
6.67039 |
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, F3, FLT3, KDR, MET, MMP12, MMP9, PTPN1, SRC, TERT, XDH |
6.66765 |
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, APEX1, APP, AR, AURKB, AXL, CA2, CA9, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, FABP4, FLT3, FUT7, GLO1, HSD17B2, KDR, MET, MMP2, MMP9, PGR, PIM1, PPARA, RORC, SRC, TERT, TOP2A, TYR |
6.66765 |
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, F3, FLT3, KDR, MET, MMP12, MMP9, PTPN1, SRC, TERT, XDH |
6.65756 |
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, CSNK2A1, CYP1B1, F3, FLT3, GLO1, IGF1R, KDR, MET, MMP9, PIM1, PTPN1, SRC, TERT, TOP2A, XDH |
6.49013 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9 |
6.22782 |
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, APEX1, APP, AR, AURKB, AXL, CA2, CA7, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, F3, FABP3, FABP4, FLT3, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
6.09398 |
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AR, AURKB, AXL, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, TYR, XDH |
5.90904 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, HSD17B1, HSD17B2 |
5.90349 |
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, CSNK2A1, CYP1B1, F3, FLT3, GLO1, IGF1R, KDR, MMP9, PIM1, PTPN1, SRC, TERT, TOP2A, XDH |
5.80274 |
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, APEX1, APP, AR, AURKB, AXL, CA12, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD2, F3, FABP3, FABP4, FLT3, HSD17B1, HSD17B2, KDR, MET, PPARA, SRC, TERT, XDH |
5.78367 |
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, DRD1, DRD2, F3, IGF1R, KDR, MET, MMP9, SRC, TERT |
5.78367 |
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, GLO1, IGF1R, KDR, MET, MMP9, PIM1, PPARA, PTPN1, SRC, TERT |
5.50195 |
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, DRD1, DRD2, F3, IGF1R, KDR, MET, MMP9, SRC, TERT |
5.45707 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, CYP1A1, CYP1A2, CYP1B1, TYR |
5.43575 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, APEX1, APP, AR, CA2, CA9, CSNK2A1, CYP1A2, DRD1, FABP3, FLT3, IGF1R, MMP2, NR3C1, PPARA, SRC |
5.3323 |
[BP] GO:0033993 |
response to lipid
|
AR, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, FABP3, FLT3, HSD17B2, NR3C1, RORC, SRC, TYR |
5.29565 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, APEX1, APP, AR, AXL, CYP1A1, CYP1A2, CYP1B1, DRD1, FABP4, FLT3, IGF1R, KDR, MMP2, MMP9, NR3C1, RORC, SRC, TERT |
5.22382 |
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AR, AURKB, AXL, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, TYR, XDH |
5.22382 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, GLO1, IGF1R, KDR, MET, MMP9, PIM1, PTPN1, SRC, TERT |
5.22382 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, DRD1, DRD2, F3, IGF1R, KDR, MET, MMP9, SRC, TERT |
5.09775 |
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, APP, CYP19A1, CYP1B1, DRD1, DRD2, F3, IGF1R, KDR, MET, MMP9, SRC, TERT |
5.08731 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, HSD17B1, HSD17B2 |
5.00241 |
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AR, AURKB, AXL, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, F3, FABP3, FABP4, FLT3, HSD17B2, IGF1R, KDR, MMP12, MMP2, MMP9, NR3C1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, TYR |
4.71105 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
APEX1, APP, AR, CYP1A1, CYP1B1, DRD1, FLT3, NR3C1, RORC, SRC |
4.6912 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, HSD17B1, HSD17B2 |
4.6912 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD2, FABP3, FABP4, FUT7, MET, PPARA |
4.6912 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, APEX1, APP, AR, AURKB, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DRD1, FABP4, FLT3, IGF1R, KDR, MMP2, MMP9, NR3C1, PTPN1, RORC, SRC, TERT, TOP2A |
4.67457 |
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, APEX1, APP, AR, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, F3, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTPN1, SRC, TERT |
4.67457 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, CSNK2A1, GLO1, IGF1R, KDR, MMP9, PIM1, PTPN1, SRC, TERT |
4.50922 |
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
4.50922 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, APP, AR, AXL, CSNK2A1, CYP1B1, DRD2, F3, FLT3, KDR, MET, MMP12, MMP9, PTPN1, SRC, TERT, XDH |
4.42309 |
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AR, CDC25B, CSNK2A1, DRD2, F3, FLT3, IGF1R, KDR, MMP12, MMP2, MMP9, PIM1, TERT |
4.34143 |
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AR, AXL, CYP1B1, DRD1, IGF1R, MMP2, MMP9, NR3C1, RORC, SRC |
4.30054 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX5, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, HSD17B1, HSD17B2, TYR, XDH |
4.29694 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, APEX1, APP, AR, AXL, CYP1A1, CYP1B1, DRD1, FABP4, FLT3, IGF1R, KDR, MMP2, NR3C1, RORC, SRC |
4.24898 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, FABP3, FABP4, GLO1, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
4.20149 |
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, APP, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD2, TYR |
4.1321 |
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, DRD2, FABP3, PPARA |
4.10004 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, APEX1, AR, CA2, CA9, CSNK2A1, CYP1A2, FABP3, FLT3, NR3C1, PPARA, SRC |
4.08325 |
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, FUT7, MMP1, MMP12, MMP2, MMP9, SRC, XDH |
3.9883 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, APP, AR, AXL, CYP1B1, DRD2, F3, FLT3, KDR, MET, PTPN1, SRC, XDH |
3.91047 |
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, APP, AR, AURKB, CDC25B, CSNK2A1, DRD1, DRD2, F3, FLT3, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
3.91047 |
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
3.88422 |
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX5, APP, AR, AXL, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, F3, FABP4, HSD17B2, IGF1R, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, RORC, SRC, TYR |
3.80612 |
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, FABP3, FABP4, GLO1, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
3.80612 |
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.78216 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, MMP9, SRC |
3.77533 |
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, NR3C1, PGR, PIM1, PPARA, RORC, SRC |
3.77465 |
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, APEX1, APP, AXL, CA12, CA2, CA7, DRD1, DRD2, FABP3, FABP4, FLT3, MET, SRC, TERT |
3.7024 |
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HSD17B1, HSD17B2 |
3.66793 |
[BP] GO:0042493 |
response to drug
|
AKR1B1, APEX1, AXL, CA9, CYP1A1, CYP1B1, DRD1, DRD2, FABP3, KDR, NR3C1, SRC |
3.66526 |
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, APP, AR, AURKB, CDC25B, DRD1, DRD2, F3, FABP3, FLT3, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
3.66526 |
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, APP, AR, AURKB, CDC25B, CSNK2A1, DRD1, DRD2, F3, FABP3, FLT3, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
3.65775 |
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4 |
3.65426 |
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, APP, AR, AURKB, CDC25B, CSNK2A1, DRD1, DRD2, F3, FLT3, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
3.6427 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, APP, AR, AXL, CSNK2A1, CYP1B1, DRD2, F3, FABP4, FLT3, KDR, MET, MMP12, MMP2, MMP9, PTPN1, SRC, TERT, XDH |
3.60952 |
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, DRD1, DRD2, FABP3, FLT3, IGF1R, MMP2, PPARA, SRC, TYR |
3.55187 |
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, DRD1, DRD2 |
3.55187 |
[BP] GO:0048869 |
cellular developmental process
|
ACHE, APP, AR, AXL, CBR1, CDC25B, CYP1A1, DRD1, DRD2, FABP4, FLT3, FUT7, GLO1, KDR, MET, MMP2, MMP9, PGR, RORC, SRC, TERT, TOP2A |
3.55187 |
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CYP1B1, DRD1, KDR, NR3C1, SRC |
3.5409 |
[BP] GO:0048511 |
rhythmic process
|
AXL, CSNK2A1, DRD2, PGR, PPARA, RORC, SRC, TOP2A |
3.52259 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, FLT3, IGF1R, KDR, PIM1, SRC |
3.52259 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, F3, FLT3, IGF1R, KDR, MET, MMP12, MMP9, PTPN1, SRC, TERT, XDH |
3.489 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD2, HSD17B1, HSD17B2 |
3.48419 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, APP, AR, AURKB, AXL, CSNK2A1, CYP1B1, DRD2, F3, FLT3, IGF1R, KDR, MET, MMP9, PTPN1, SRC, XDH |
3.47622 |
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, MET, MMP9, PPARA, SRC, TERT |
3.4193 |
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1A1, CYP1B1, DRD1, DRD2, KDR, SRC |
3.4193 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, APP, AR, AURKB, AXL, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, F3, FLT3, IGF1R, KDR, MET, MMP12, MMP9, PTPN1, SRC, TERT, XDH |
3.4193 |
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, CA2, CA7, DRD1, DRD2, KDR, SRC |
3.39181 |
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, DRD2 |
3.39181 |
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2 |
3.37917 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, APP, AR, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, FLT3, HSD17B2, KDR, MMP9, PGR, PIM1, PPARA, RORC, SRC, TYR |
3.3286 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.29757 |
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, DRD1, DRD2, FABP3, FLT3, IGF1R, MMP2, PPARA, SRC, TYR |
3.28794 |
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, DRD2, FABP3, PPARA |
3.27975 |
[BP] GO:0010038 |
response to metal ion
|
APP, CA2, CYP1A1, CYP1A2, DRD2, FABP4, MMP9, TERT |
3.23293 |
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CSNK2A1, CYP1B1, DRD2, FABP4, IGF1R, MET, MMP9, PIM1, PPARA, PTPN1, SRC |
3.19432 |
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, CA2, CYP1A1, DRD1, DRD2, MMP2, PPARA, SRC, TERT, TYR |
3.17955 |
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, DRD1, F3, IGF1R, KDR, MET, MMP9, SRC, TERT |
3.14289 |
[BP] GO:1901989 |
None
|
APEX1, APP, CDC25B, CYP1A1, TERT |
3.13807 |
[BP] GO:0048513 |
animal organ development
|
ACHE, AR, AXL, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, FLT3, HSD17B2, KDR, PPARA, SRC, TYR |
3.12674 |
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, DRD1, F3, IGF1R, KDR, MET, MMP9, SRC, TERT |
3.03891 |
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, APP, AR, AURKB, AXL, CDC25B, CSNK2A1, CYP1A1, CYP1A2, CYP3A4, DRD1, DRD2, F3, FLT3, FUT7, GLO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTPN1, SRC, TOP2A, TYR, XDH |
3.03591 |
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, APP, AR, AURKB, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, F3, FABP3, FABP4, FLT3, GLO1, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
3.02033 |
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, NR3C1, NR3C2, PGR, PPARA, RORC |
2.98905 |
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.98905 |
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, DRD1, F3, IGF1R, KDR, MET, MMP9, SRC, TERT |
2.96227 |
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AR, AURKB, DRD1, DRD2, FABP3, IGF1R, KDR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SRC, TERT, TOP2A |
2.96227 |
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, APEX1, APP, AR, AURKB, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1B1, DRD1, DRD2, F3, FABP3, FABP4, FLT3, GLO1, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.91931 |
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, APP, AR, AURKB, CA9, CDC25B, CSNK2A1, CYP1A2, CYP1B1, DRD1, DRD2, F3, FABP4, FLT3, GLO1, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.88891 |
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1 |
2.88137 |
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, CYP1A1, DRD2, MMP2, PPARA, SRC, TERT |
2.87339 |
[BP] GO:0042752 |
None
|
ADORA1, DRD2, PPARA, RORC, TOP2A |
2.8659 |
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, DRD1, F3, IGF1R, KDR, MET, MMP9, SRC, TERT |
2.85971 |
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, APP, AR, AURKB, CA9, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD2, F3, FABP3, FABP4, FLT3, GLO1, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.85305 |
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, SRC, TERT |
2.83308 |
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, APP, CYP19A1, DRD2, F3, FABP4, IGF1R, MET, MMP12, MMP2, PPARA, PTPN1, SRC, TERT, XDH |
2.82981 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, MMP9, SRC |
2.82672 |
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, APP, AR, CDC25B, DRD1, DRD2, FABP3, FLT3, KDR, MMP9, PTPN1, SRC, XDH |
2.82571 |
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, APP, AR, CDC25B, DRD1, DRD2, FABP3, FLT3, KDR, MMP9, PTPN1, SRC, XDH |
2.82571 |
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, CYP1A1, DRD2, MMP2, PPARA, SRC, TERT |
2.82041 |
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, CDC25B, CSNK2A1, DRD1, FLT3, IGF1R, KDR, MET, PIM1, SRC |
2.82041 |
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, FLT3, IGF1R, KDR, MET, MMP2, MMP9, PTPN1, SRC |
2.81241 |
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, NR3C1, SRC |
2.78959 |
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1 |
2.78466 |
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, TERT |
2.76551 |
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DRD1, DRD2 |
2.75557 |
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, APP, AR, DRD2, FLT3, KDR, PTPN1, SRC, XDH |
2.75557 |
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP3A4 |
2.74122 |
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, APEX1, APP, AR, AURKB, CA9, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD2, F3, FABP3, FABP4, FLT3, GLO1, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.73406 |
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, APP, AR, CDC25B, DRD1, DRD2, FABP4, FLT3, IGF1R, KDR, MMP9, PPARA, PTPN1, SRC, XDH |
2.73406 |
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, SRC |
2.72969 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.71564 |
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
APP, AR, AURKB, DRD1, DRD2, IGF1R, MET, MMP12, NR3C1, PGR, PPARA, PTPN1, RORC, SRC, TERT, TOP2A |
2.68461 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.68413 |
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA4, CA7, CA9, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, TYR, XDH |
2.67173 |
[BP] GO:0019369 |
arachidonic acid metabolic process
|
CBR1, CYP1A1, CYP1A2, CYP1B1 |
2.66369 |
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, APP, AR, CDC25B, DRD1, DRD2, FABP3, FABP4, FLT3, IGF1R, KDR, MMP9, PPARA, PTPN1, SRC, XDH |
2.64479 |
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, CYP1A1, DRD2, MMP2, PPARA, SRC, TERT |
2.63937 |
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP3A4, RORC |
2.6392 |
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, MMP9, SRC |
2.63533 |
[BP] GO:0022414 |
reproductive process
|
AKR1B1, APP, AR, AXL, CDC25B, CYP19A1, CYP1A1, DRD1, HSD17B2, MMP2, MMP9, PGR, SRC, TOP2A |
2.61649 |
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, APEX1, APP, AURKB, AXL, CDC25B, CSNK2A1, DRD1, DRD2, FLT3, IGF1R, KDR, MET, PIM1, PTPN1, SRC, XDH |
2.61649 |
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, APP, AR, CDC25B, DRD1, DRD2, FABP3, FABP4, FLT3, IGF1R, KDR, MMP9, PPARA, PTPN1, SRC, XDH |
2.61649 |
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, FABP3, PPARA |
2.60707 |
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, APP, AR, DRD1, FLT3, IGF1R, MMP2, NR3C1, SRC |
2.60707 |
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, DRD1, DRD2, MET |
2.58416 |
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, CA2, CA7, DRD1, DRD2 |
2.57231 |
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, CA2, CA7, DRD1, DRD2 |
2.57231 |
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR |
2.55893 |
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, APP, AR, CDC25B, DRD1, DRD2, FABP4, FLT3, IGF1R, KDR, MMP9, PTPN1, SRC, XDH |
2.55893 |
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
APP, AR, AURKB, DRD1, DRD2, FABP3, IGF1R, MET, MMP12, NR3C1, PGR, PPARA, RORC, SRC, TERT, TOP2A |
2.55893 |
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, CYP3A4 |
2.55893 |
[BP] GO:0060748 |
None
|
AR, PGR |
2.55893 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.55893 |
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, NR3C1, NR3C2, PGR, PPARA, RORC |
2.54112 |
[BP] GO:0030198 |
extracellular matrix organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.52943 |
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, APP, AR, AURKB, CSNK2A1, DRD2, FABP4, IGF1R, KDR, MET, MMP12, MMP9, NR3C1, PGR, PPARA, PTPN1, RORC, SRC, TERT, XDH |
2.52497 |
[BP] GO:0043062 |
extracellular structure organization
|
APP, CYP1B1, KDR, MMP1, MMP12, MMP2, MMP9 |
2.52497 |
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1 |
2.51283 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.50307 |
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP3A4 |
2.50307 |
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HSD17B1, HSD17B2 |
2.4887 |
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, F3, MET, SRC, XDH |
2.4887 |
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, APP, AR, DRD2, FLT3, IGF1R, KDR, PTPN1, SRC, XDH |
2.47048 |
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AXL, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, MMP2, MMP9, PPARA, PTPN1, SRC, TERT, TOP2A |
2.46948 |
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
MMP2, MMP9, TERT |
2.45287 |
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, DRD1, DRD2 |
2.44774 |
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.42357 |
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, APEX1, APP, AURKB, AXL, CDC25B, CSNK2A1, DRD1, DRD2, FLT3, IGF1R, KDR, MET, PIM1, PTPN1, SRC, XDH |
2.42357 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.40165 |
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, APP, AR, AURKB, CDC25B, CSNK2A1, DRD1, DRD2, F3, FABP4, FLT3, IGF1R, MMP9, PTPN1, SRC, TERT, XDH |
2.36729 |
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.34877 |
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AR, AURKB, DRD2, IGF1R, KDR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SRC, TERT, TOP2A |
2.33637 |
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1 |
2.33345 |
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, APP, AR, AURKB, AXL, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, F3, FABP4, FLT3, IGF1R, KDR, MET, MMP12, MMP2, MMP9, PPARA, PTPN1, SRC, TERT, XDH |
2.32155 |
[BP] GO:1901992 |
positive regulation of mitotic cell cycle phase transition
|
APEX1, APP, CYP1A1, TERT |
2.31697 |
[BP] GO:0007416 |
None
|
ACHE, APP, DRD1, DRD2 |
2.31697 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
CA2, CA7 |
2.31697 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.31697 |
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, AR, DRD1, DRD2, IGF1R, MET, MMP12, MMP9, PTPN1, SRC, TERT, XDH |
2.2975 |
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, CYP1B1, MMP9, SRC |
2.29342 |
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, MET, MMP9, PPARA, SRC, TERT |
2.29342 |
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ACHE, AKR1B1, AKR1B10, APEX1, APP, AR, AURKB, AXL, CDC25B, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, F3, FLT3, FUT7, GLO1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, TYR, XDH |
2.29342 |
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, AR, DRD1, DRD2, IGF1R, MET, MMP12, MMP9, PTPN1, SRC, TERT, XDH |
2.29154 |
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, AR, CYP19A1, DRD1, DRD2, IGF1R, MET, MMP12, MMP9, PPARA, PTPN1, SRC, TERT, XDH |
2.27961 |
[BP] GO:0006706 |
steroid catabolic process
|
CYP19A1, CYP1A2, CYP3A4 |
2.27424 |
[BP] GO:0044243 |
multicellular organismal catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.26911 |
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, TERT |
2.26911 |
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, CA2, CA7, DRD1, DRD2, KDR, SRC |
2.26874 |
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, IGF1R, PPARA, SRC |
2.26022 |
[BP] GO:0071383 |
None
|
AR, FLT3, NR3C1, SRC |
2.25182 |
[BP] GO:0032787 |
None
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, FABP3, GLO1, PPARA |
2.24893 |
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, APP, AR, CDC25B, DRD2, FLT3, KDR, MMP9, PTPN1, SRC, XDH |
2.22785 |
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, DRD2, F3, FABP4, KDR, MET, MMP12, PPARA |
2.21583 |
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, MMP2, MMP9, TERT |
2.21583 |
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA2, CA7, CA9, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, F3, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, XDH |
2.20963 |
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, NR3C1, PGR, SRC |
2.17721 |
[BP] GO:0018958 |
None
|
AKR1B1, DRD1, DRD2, TYR |
2.17721 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, FABP3, FLT3, PPARA, RORC, SRC |
2.17339 |
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, APP, AXL, CA2, CYP19A1, DRD1, DRD2, MMP12, SRC, TERT |
2.17339 |
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
APP, AR, AXL, CA2, CYP1B1, DRD2, F3, KDR, MET, MMP12, MMP9, PIM1, SRC, TERT |
2.16289 |
[BP] GO:0022617 |
extracellular matrix disassembly
|
MMP1, MMP12, MMP2, MMP9 |
2.16289 |
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1 |
2.15268 |
[BP] GO:0021853 |
None
|
DRD1, DRD2 |
2.15268 |
[BP] GO:0010641 |
None
|
F3, SRC |
2.15268 |
[BP] GO:1904936 |
None
|
DRD1, DRD2 |
2.15268 |
[BP] GO:0042321 |
None
|
ADORA1, DRD2 |
2.15268 |
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, CDC25B, CSNK2A1, DRD1, FLT3, IGF1R, KDR, MET, PIM1, SRC |
2.15268 |
[BP] GO:1901655 |
None
|
AKR1B1, AR, NR3C1, SRC |
2.13651 |
[BP] GO:0032963 |
collagen metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.13651 |
[BP] GO:0008283 |
cell proliferation
|
ACHE, AR, AURKB, CYP1A1, FLT3, MET, PIM1, SRC, TYR |
2.11367 |
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, APP, AR, AURKB, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD2, F3, FABP4, FLT3, IGF1R, MET, MMP9, PIM1, PPARA, PTPN1, SRC, TERT, XDH |
2.10307 |
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, APP, AR, CDC25B, DRD2, FLT3, KDR, MMP9, PTPN1, SRC, XDH |
2.09935 |
[BP] GO:0001659 |
None
|
ADORA1, DRD1, DRD2 |
2.09935 |
[BP] GO:0002521 |
leukocyte differentiation
|
AXL, FLT3, FUT7, GLO1, MMP9, RORC |
2.08786 |
[BP] GO:0030336 |
None
|
ADORA1, ADORA3, APEX1, CYP19A1, CYP1B1, DRD2 |
2.05502 |
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.05227 |
[BP] GO:0016477 |
cell migration
|
AXL, CYP1B1, DRD1, DRD2, FUT7, KDR, MMP1, MMP12, MMP9, SRC |
2.03426 |
[BP] GO:0019219 |
regulation of nucleobase-containing compound metabolic process
|
ADORA3, APEX1, APP, AR, AURKB, CA9, CSNK2A1, CYP1B1, DRD1, DRD2, FABP4, GLO1, IGF1R, MET, MMP12, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A |
2.03396 |
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, FLT3, IGF1R, KDR, MET, MMP2, MMP9, PTPN1, SRC |
2.03301 |
[BP] GO:0006775 |
fat-soluble vitamin metabolic process
|
CBR1, CYP1A1, CYP3A4 |
2.03042 |
[BP] GO:0021843 |
None
|
DRD1, DRD2 |
2.01794 |
[BP] GO:0021830 |
None
|
DRD1, DRD2 |
2.01794 |
[BP] GO:0002933 |
lipid hydroxylation
|
CYP1A1, CYP3A4 |
2.01794 |
[BP] GO:0021826 |
None
|
DRD1, DRD2 |
2.01794 |
[BP] GO:0016098 |
monoterpenoid metabolic process
|
CYP1A2, CYP3A4 |
2.01794 |
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, APP, AR, AXL, CA1, CA2, CSNK2A1, CYP1B1, DRD1, DRD2, F3, FLT3, IGF1R, KDR, MET, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC |
2.0066 |
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DRD1, IGF1R, MMP2, SRC |
2.00482 |
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, DRD2, MMP12, PPARA |
2.00225 |
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, APP, AR, AURKB, CA1, CA2, CA4, CA7, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, FABP3, FABP4, FLT3, FUT7, GLO1, HSD17B1, HSD17B2, KDR, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PTPN1, SRC, TERT, TOP2A, TYR, XDH |
2.82981 |
[CC] GO:0097443 |
sorting endosome
|
KDR, PTPN1 |
2.01794 |
[CC] GO:0043227 |
membrane-bounded organelle
|
ACHE, ADORA1, AKR1B1, AKR1B10, APEX1, APP, AR, AURKB, AXL, CA1, CA2, CA4, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, IGF1R, KDR, MMP12, MMP2, MMP9, NR3C1, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, TYR, XDH |
1.83656 |
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP |
1.80867 |
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ALOX5, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, F3, FLT3, FUT7, GLO1, HSD17B2, IGF1R, KDR, MET, MMP2, NR3C2, PGR, PIM1, PTPN1, SRC, TERT, TYR |
1.75502 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, APP, AR, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, GLO1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, TYR, XDH |
16.0258 |
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX5, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, F3, FABP3, FABP4, FLT3, GLO1, HSD17B1, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, SRC, TERT, TOP2A, TYR, XDH |
11.6106 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
10.3294 |
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, F3, FLT3, FUT7, GLO1, HSD17B1, HSD17B2, IGF1R, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PTPN1, SRC, TERT, TOP2A, TYR, XDH |
8.66617 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, GLO1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, TERT, TOP2A, TYR, XDH |
7.92177 |
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA4, CA7, CA9, GLO1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PPARA, PTPN1, RORC |
7.92177 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.23979 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.67467 |
[MF] GO:0046872 |
metal ion binding
|
ALOX5, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, GLO1, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, PGR, PIM1, PPARA, PTPN1, RORC, TERT, TOP2A, TYR, XDH |
6.34287 |
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA7, CA9, GLO1 |
5.80274 |
[MF] GO:0005496 |
steroid binding
|
AR, CYP3A4, HSD17B1, NR3C1, NR3C2, PGR, RORC |
5.54179 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4 |
5.51701 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4 |
5.29565 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX5, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, HSD17B1, HSD17B2, TYR, XDH |
5.25127 |
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, NR3C1, NR3C2, PGR, PPARA, RORC |
5.12608 |
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD2, FLT3, IGF1R, KDR, MET, PIM1, PPARA, SRC, TOP2A |
4.32266 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4 |
4.23423 |
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, TYR |
4.04781 |
[MF] GO:0005506 |
iron ion binding
|
ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, XDH |
3.9883 |
[MF] GO:0008289 |
lipid binding
|
AR, AXL, CYP3A4, F3, FABP3, FABP4, HSD17B1, NR3C1, NR3C2, PGR, PPARA, RORC |
3.9883 |
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AR, AXL, DRD1, DRD2, F3, FLT3, IGF1R, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC |
3.66526 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.65775 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, SRC |
3.44302 |
[MF] GO:0016725 |
oxidoreductase activity, acting on CH or CH2 groups
|
CYP1A2, CYP3A4, XDH |
3.4193 |
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, CBR1, HSD17B1, HSD17B2, XDH |
3.32661 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, SRC |
3.29757 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, FLT3, IGF1R, KDR, MET |
3.24796 |
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, FLT3, IGF1R, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SRC |
3.24495 |
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AR, AXL, DRD1, DRD2, F3, FLT3, IGF1R, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC |
3.12733 |
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, HSD17B1, IGF1R, NR3C1 |
3.12332 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, TYR |
3.0533 |
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AR, AXL, DRD1, DRD2, F3, FLT3, IGF1R, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC |
2.98141 |
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, PGR, PPARA, RORC |
2.78959 |
[MF] GO:0004879 |
nuclear receptor activity
|
AR, PGR, PPARA, RORC |
2.78959 |
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, FLT3, IGF1R, KDR, MMP12, MMP9, PPARA, PTPN1, SRC |
2.76551 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, MET, SRC |
2.76384 |
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AR, AXL, DRD1, DRD2, F3, FLT3, IGF1R, KDR, MET, NR3C1, NR3C2, PGR, PPARA, RORC |
2.71367 |
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HSD17B1, HSD17B2 |
2.57231 |
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.55893 |
[MF] GO:0034875 |
caffeine oxidase activity
|
CYP1A2, CYP3A4 |
2.31697 |
[MF] GO:0033695 |
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
|
CYP1A2, CYP3A4 |
2.31697 |
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, HSD17B1, SRC, XDH |
2.22741 |
[MF] GO:0101020 |
estrogen 16-alpha-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.15268 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, FLT3, IGF1R, KDR, MET, PIM1, SRC |
2.11699 |
[MF] GO:0005158 |
None
|
IGF1R, PTPN1, SRC |
2.09935 |
[MF] GO:0051879 |
Hsp90 protein binding
|
CSNK2A1, KDR, NR3C1 |
2.06088 |
[MF] GO:0004064 |
arylesterase activity
|
CA1, CA2 |
2.01794 |
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP3A4 |
2.00585 |