GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
13.2881 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
12.6406 |
[BP] GO:0008152 |
metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
10.9981 |
[BP] GO:0065008 |
regulation of biological quality
|
ABCG2, ACHE, ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CA12, CA2, CA7, CDK6, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD3, EGFR, ESR1, F2, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, MET, PPARA, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
10.582 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA2, CA3, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, PPARA, SMAD3, SRC, TEK, TYR |
9.48158 |
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD3, EGFR, F2, F3, FLT3, GPR35, HCAR2, HSPA1A, INSR, KDR, MET, MMP12, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.21298 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA3, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD3, EGFR, ESR1, ESRRA, FABP3, HSD11B2, HSD17B2, IGF1R, INSR, PPARA, SRC, TEK, TYR |
9.21298 |
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD3, EGFR, F2, F3, FLT3, GPR35, HCAR2, HSPA1A, INSR, KDR, MET, MMP12, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.21251 |
[BP] GO:0044281 |
small molecule metabolic process
|
ABCG2, AKR1B1, AKR1B10, ALOX5, AOX1, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FUT7, GBA2, GLO1, HSPA1A, PIM1, PPARA, TYR, XDH |
8.85152 |
[BP] GO:0044237 |
cellular metabolic process
|
ABCG2, ACHE, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
8.85152 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, ESR1, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
8.02596 |
[BP] GO:0042221 |
response to chemical
|
ABCG2, AKR1B1, ALPL, APEX1, AXL, BCL2, CA2, CA3, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, PPARA, SMAD3, SRC, TEK, TYR |
7.90017 |
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, DRD3, EGFR, ESR1, ESRRA, F2, F3, FABP3, FLT3, HSPA1A, IGF1R, INSR, KDR, MMP12, NUAK1, PIM1, SMAD3, SRC, TEK, XDH |
7.80501 |
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD3, EGFR, ESR1, ESRRA, FLT3, HSD11B2, SRC, TEK, TYR |
7.79597 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, INSR, PPARA, SRC, TEK |
7.54029 |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, EGFR, ESR1, FABP3, FABP4, FUT7, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, PPARA |
7.36256 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DRD1, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, IGF1R, INSR, PPARA, SMAD3, SRC, TEK |
7.34883 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
7.10204 |
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HSPA1A, IGF1R, KDR, MET, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TOP2A, XDH |
7.09805 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FLT3, GPR35, HCAR2, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
7.04148 |
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HSPA1A, IGF1R, KDR, MET, PIM1, PTPN1, SMAD3, SRC, TEK, TOP2A, XDH |
7.04148 |
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, SRC, TYR |
7.0341 |
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CDK6, DRD1, DRD3, EGFR, F2, HCAR2, KDR, SRC, TNKS, TNKS2 |
6.81934 |
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, PPARA, SMAD3, SRC, TEK, TYR |
6.81093 |
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD3, FABP3, PPARA |
6.564 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, F2, F3, FLT3, GPR35, HCAR2, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
6.564 |
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HSPA1A, IGF1R, KDR, PIM1, PTPN1, SMAD3, SRC, TEK, TOP2A, XDH |
6.45666 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, F2, F3, FLT3, GPR35, HCAR2, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
6.44827 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, AXL, BCL2, CSNK2A1, CYP1B1, DRD3, EGFR, F2, F3, FLT3, GPR35, HSPA1A, INSR, KDR, MET, MMP12, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
6.42615 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, TYR |
6.36541 |
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, APEX1, AXL, BCL2, CA2, CA7, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD3, EGFR, F2, F3, GPR35, HCAR2, HSPA1A, IGF1R, INSR, KCNA3, KDR, MET, MMP12, PPARA, PTPN1, SMAD3, SRC, TEK |
6.1319 |
[BP] GO:0042493 |
response to drug
|
ABCG2, AKR1B1, APEX1, AXL, BCL2, CA3, CA9, CDK6, CYP1A1, CYP1B1, DRD1, DRD3, EGFR, FABP3, HSD11B2, KDR, SRC |
6.12008 |
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
5.94701 |
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.84179 |
[BP] GO:0042592 |
homeostatic process
|
ABCG2, ADORA1, AKR1B1, APEX1, AXL, BCL2, CA12, CA2, CA7, DRD1, DRD3, EGFR, ESR1, F2, FABP3, FABP4, FLT3, GPR35, INSR, MET, SMAD3, SRC |
5.83923 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, PIM1, SRC, TEK |
5.8274 |
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DUSP3, EGFR, ESR1, ESRRA, ESRRB, F2, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD17B2, INSR, KDR, MET, PIM1, PPARA, SMAD3, SRC, TEK, TNKS2, TOP2A, TYR |
5.81656 |
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD3, EGFR, F3, IGF1R, INSR, KDR, MET, SMAD3, SRC, TEK |
5.7696 |
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALPL, APEX1, AURKB, AXL, BCL2, CA3, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPN1, SRC, TEK, TNKS, XDH |
5.68573 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD3, DUSP3, EGFR, ESR1, F2, F3, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PTPN1, SRC, TEK, XDH |
5.66227 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, EGFR, ESR1, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.62305 |
[BP] GO:0050896 |
response to stimulus
|
ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA3, CA6, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD3, EGFR, ESR1, ESRRA, F2, F3, FABP3, FABP4, FLT3, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MMP12, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, TOP2A, TYR |
5.5476 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD17B1, HSD17B2 |
5.54658 |
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, SMAD3, SRC, TEK |
5.49918 |
[BP] GO:0006468 |
protein phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TNKS |
5.49376 |
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, IGF1R, KDR, MET, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK |
5.40176 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPR35, HSPA1A, IGF1R, KDR, MET, MMP12, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
5.35361 |
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALPL, APEX1, AURKB, AXL, BCL2, CA3, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPN1, SRC, TEK, TNKS, XDH |
5.35361 |
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, DRD1, DRD3, EGFR, F2, HCAR2, TNKS, TNKS2 |
5.35221 |
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD3, FABP3, PPARA |
5.3297 |
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ABCG2, ACHE, AKR1B1, ALPL, AOX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP3A4, DRD1, DRD3, DUSP3, EGFR, ESR1, F2, F3, FLT3, FUT7, GBA2, GLO1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
5.30876 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AXL, BCL2, CYP1B1, EGFR, F2, F3, FLT3, GPR35, HSPA1A, INSR, KDR, MET, PTPN1, SRC, TEK, XDH |
5.26966 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, IGF1R, KDR, MET, PIM1, PTPN1, SMAD3, SRC, TEK |
5.22163 |
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, TNKS, TOP2A |
5.1945 |
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, SMAD3, SRC, TEK |
5.14111 |
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, BCL2, CDC25B, CDK6, CSNK2A1, DRD3, EGFR, ESR1, F2, F3, FLT3, IGF1R, INSR, KDR, MMP12, PIM1, TEK |
5.13699 |
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, SMAD3, SRC, TEK |
5.08478 |
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA3, CYP1A1, CYP1B1, DRD1, DRD3, KDR, SRC |
5.02107 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
5.01791 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.96918 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, AXL, BCL2, CSNK2A1, CYP1B1, DRD3, EGFR, ESRRA, F2, F3, FABP4, FLT3, GPR35, HSPA1A, INSR, KDR, MET, MMP12, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
4.94305 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALPL, AXL, BCL2, CA2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DUSP3, EGFR, ESR1, ESRRA, ESRRB, F2, FLT3, GBA2, HSD11B1, HSD17B2, INSR, KDR, PIM1, PPARA, SMAD3, SRC, TEK, TYR |
4.92357 |
[BP] GO:0071704 |
organic substance metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
4.90236 |
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPR35, HCAR2, HSPA1A, IGF1R, KDR, MET, MMP12, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
4.82364 |
[BP] GO:0048878 |
chemical homeostasis
|
ABCG2, AKR1B1, BCL2, CA12, CA2, CA7, DRD1, DRD3, EGFR, ESR1, F2, FABP3, FABP4, GPR35, INSR, MET, SMAD3 |
4.80075 |
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
4.69323 |
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, BCL2, CDK6, CYP19A1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, F2, HSPA1A, IGF1R, MET, MMP12, PPARA, PTPN1, SMAD3, SRC, TEK, XDH |
4.69323 |
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, DRD1, DRD3, F2, KDR, SRC |
4.669 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, IGF1R, KDR, PIM1, PTPN1, SMAD3, SRC, TEK |
4.6331 |
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
4.6326 |
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD3, EGFR, F3, INSR, MET, SRC, TEK, XDH |
4.63024 |
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, F3, FABP4, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
4.59491 |
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, EGFR, F2, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK, TNKS, TOP2A |
4.49966 |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, APEX1, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, EGFR, FABP4, KDR, SRC |
4.47091 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2, TYR, XDH |
4.39817 |
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
4.38588 |
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, DRD3, EGFR, ESR1, F2, F3, FABP4, KDR, MET, MMP12, PPARA, SMAD3, TEK |
4.38588 |
[BP] GO:0016310 |
phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TNKS |
4.37026 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.36397 |
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
4.35102 |
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, BCL2, CDC25B, DRD1, DRD3, DUSP3, EGFR, ESRRB, F2, FABP3, FABP4, FLT3, IGF1R, INSR, KDR, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, XDH |
4.28881 |
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AXL, BCL2, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESRRB, F2, F3, FABP4, HSD11B2, HSD17B2, IGF1R, INSR, MET, MMP12, PIM1, PPARA, SMAD3, SRC, TEK, TNKS2, TYR |
4.28877 |
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD3, DUSP3, EGFR, ESR1, ESR2, F2, F3, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
4.2811 |
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, BCL2, CDC25B, DRD1, DRD3, DUSP3, EGFR, ESRRB, F2, FABP3, FABP4, FLT3, IGF1R, INSR, KDR, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, XDH |
4.24058 |
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
4.23336 |
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, CDK6, CYP19A1, DUSP3, EGFR, ESR1, F2, F3, FABP4, HSPA1A, IGF1R, MET, MMP12, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, XDH |
4.21957 |
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, BCL2, CYP1A1, EGFR, F2, PPARA, SMAD3 |
4.13829 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, SMAD3, SRC |
4.11909 |
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD3, GBA2, TYR |
4.10142 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, IGF1R, INSR, KDR, SMAD3, SRC |
4.07266 |
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, AURKB, BCL2, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, F2, F3, FABP4, FLT3, GPR35, HSPA1A, IGF1R, INSR, MET, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
4.05394 |
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.045 |
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD3, DUSP3, EGFR, ESR1, F2, F3, FABP4, FLT3, HSPA1A, IGF1R, INSR, NUAK1, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
4.01412 |
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, EGFR, HSPA1A |
3.9453 |
[BP] GO:0030335 |
positive regulation of cell migration
|
BCL2, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, SMAD3, SRC, TEK |
3.85285 |
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, GBA2 |
3.85285 |
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD3, EGFR, HSD11B2, HSPA1A, PPARA, SMAD3, SRC, TEK, TYR |
3.83687 |
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, DRD1, DRD3, EGFR, FABP3, FLT3, HSD11B2, IGF1R, INSR, PPARA, SRC, TEK, TYR |
3.83687 |
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.80366 |
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, BCL2, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, GPR35, HSPA1A, IGF1R, MET, MMP12, PTPN1, SMAD3, SRC, XDH |
3.77771 |
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, BCL2, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, GPR35, HSPA1A, IGF1R, MET, MMP12, PTPN1, SMAD3, SRC, XDH |
3.76164 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, DRD3, F2, FABP3, FLT3, HCAR2, PPARA, SRC, TEK |
3.74989 |
[BP] GO:2000147 |
positive regulation of cell motility
|
BCL2, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, SMAD3, SRC, TEK |
3.7319 |
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, KDR, SRC |
3.72995 |
[BP] GO:0050801 |
ion homeostasis
|
ABCG2, BCL2, CA12, CA2, CA7, DRD1, DRD3, EGFR, ESR1, F2, FABP3, GPR35, SMAD3 |
3.71391 |
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD3, EGFR, ESR1, PPARA, SRC, TOP2A |
3.71391 |
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, SRC, TNKS, TOP2A |
3.70668 |
[BP] GO:0051272 |
positive regulation of cellular component movement
|
BCL2, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, SMAD3, SRC, TEK |
3.64109 |
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F3, INSR, MET, SRC, TEK |
3.57981 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, NUAK1, PTPN1, SMAD3, SRC, TOP2A |
3.5569 |
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.5454 |
[BP] GO:0040017 |
positive regulation of locomotion
|
BCL2, DRD1, EGFR, F3, IGF1R, INSR, KDR, MET, SMAD3, SRC, TEK |
3.50991 |
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, DRD1, DRD3, EGFR, FABP3, FLT3, HSD11B2, IGF1R, INSR, PPARA, SRC, TEK, TYR |
3.50991 |
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
AURKB, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, IGF1R, INSR, KDR, MET, MMP12, PPARA, SMAD3, SRC, TNKS, TNKS2, TOP2A |
3.50776 |
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
3.48555 |
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, SMAD3, SRC, TEK |
3.4321 |
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, AXL, BCL2, CA2, CDK6, CYP1B1, DRD3, EGFR, ESR1, ESRRA, ESRRB, F2, F3, GPR35, HCAR2, HSPA1A, INSR, KDR, MET, MMP12, PIM1, SMAD3, SRC, TEK, TNKS2, XDH |
3.42703 |
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, AXL, BCL2, CA2, CYP19A1, DRD1, DRD3, EGFR, F2, HCAR2, INSR, MMP12, SMAD3, SRC |
3.42321 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, EGFR, FABP3, FABP4, FUT7, GBA2, MET, PPARA |
3.42055 |
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, BCL2, CDC25B, DRD1, EGFR, ESRRB, F2, FABP3, FLT3, INSR, KDR, PTPN1, SMAD3, SRC, TEK, XDH |
3.39743 |
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, BCL2, CDC25B, DRD1, EGFR, ESRRB, F2, FABP3, FLT3, INSR, KDR, PTPN1, SMAD3, SRC, TEK, XDH |
3.39743 |
[BP] GO:0010638 |
positive regulation of organelle organization
|
AURKB, BCL2, DRD3, HSPA1A, INSR, KDR, MET, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.36786 |
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP3A4, EGFR |
3.361 |
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, AXL, BCL2, CA2, CA7, CYP19A1, DRD1, DRD3, EGFR, F2, GPR35, HCAR2, HSPA1A, INSR, KCNA3, MMP12, PPARA, PTPN1, SMAD3, SRC |
3.35652 |
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, SRC |
3.34564 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, SRC |
3.34564 |
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, F2, INSR, SMAD3, XDH |
3.33331 |
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, HCAR2, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
3.32964 |
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, F2, MMP12, PPARA, SMAD3, TEK |
3.30479 |
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
AURKB, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, IGF1R, INSR, MET, MMP12, PPARA, PTPN1, SMAD3, SRC, TNKS, TNKS2, TOP2A |
3.28804 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, SRC |
3.2627 |
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PIM1, PPARA, SRC |
3.25396 |
[BP] GO:0098771 |
inorganic ion homeostasis
|
ABCG2, BCL2, CA12, CA2, CA7, DRD1, DRD3, EGFR, ESR1, F2, GPR35, SMAD3 |
3.21846 |
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CYP19A1, F2, PPARA, SMAD3, TEK |
3.21846 |
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, AXL, BCL2, CA3, CYP1B1, EGFR, HSPA1A, SRC |
3.15317 |
[BP] GO:0008283 |
cell proliferation
|
ACHE, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, MET, PIM1, SRC, TEK, TYR |
3.14509 |
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, AURKB, CSNK2A1, CYP1B1, DRD3, DUSP3, ESR1, FABP4, GPR35, IGF1R, MET, PIM1, PPARA, PTPN1, SRC, TNKS |
3.14246 |
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, HSD11B2, PPARA, SMAD3, SRC, TEK |
3.14112 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.13218 |
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, FABP3, HSD11B2, IGF1R, INSR, PPARA, SRC, TEK |
3.10706 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FLT3, SRC |
3.08946 |
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
F2, FLT3, SRC, TEK |
3.07886 |
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
3.07886 |
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
F2, FABP3, FLT3, PPARA, SRC, TEK |
3.07886 |
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, EGFR, ESR1, F2, FABP4, HSPA1A, MMP12, PPARA, PTPN1, SMAD3, SRC, TEK |
3.07828 |
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, INSR, KDR, MET, PPARA, PTPN1, SMAD3 |
3.07488 |
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, HSD11B2, PPARA, SMAD3, SRC, TEK |
3.06573 |
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP3A4, EGFR |
3.04783 |
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, SRC |
3.00584 |
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, BCL2, CDC25B, DRD1, DUSP3, EGFR, ESRRB, F2, FABP4, FLT3, IGF1R, INSR, KDR, PPARA, PTPN1, SRC, TEK, XDH |
2.9852 |
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
AURKB, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, IGF1R, INSR, KDR, MET, MMP12, PPARA, SMAD3, SRC, TNKS, TNKS2, TOP2A |
2.98268 |
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, SRC |
2.96359 |
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, DRD3, F2, PPARA, SMAD3, TEK |
2.94473 |
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, AURKB, CDC25B, CYP1A1, DRD3, DUSP3, EGFR, INSR, SRC |
2.93089 |
[BP] GO:0002009 |
morphogenesis of an epithelium
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.91542 |
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD1, DRD3, TYR |
2.90291 |
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
AXL, BCL2, CA2, CYP1B1, DRD3, EGFR, ESRRB, F2, F3, HCAR2, HSPA1A, KDR, MET, MMP12, PIM1, SMAD3, SRC, TEK |
2.88551 |
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, HCAR2, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
2.88211 |
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP4, FLT3, GLO1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
2.87054 |
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, HSD11B2, PPARA, SMAD3, SRC, TEK |
2.83173 |
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.83126 |
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.82341 |
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, SRC |
2.81699 |
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD3, EGFR, HSPA1A, INSR, TNKS |
2.81079 |
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CYP19A1, EGFR, ESR1, F2, FABP4, PPARA, SMAD3, TEK |
2.80934 |
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F2, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.80934 |
[BP] GO:0036211 |
protein modification process
|
ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F2, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.80934 |
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.79589 |
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, AURKB, BCL2, CDC25B, EGFR, ESR1, F2, F3, FLT3, HSPA1A, INSR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
2.76182 |
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, CDC25B, CYP1A1, DRD3, DUSP3, INSR |
2.76182 |
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, PTPN1, SRC, TEK |
2.76182 |
[BP] GO:0009987 |
cellular process
|
ABCG2, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, HCAR2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KCNA3, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
2.75288 |
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.74606 |
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, AURKB, BCL2, CDC25B, EGFR, ESR1, ESR2, F2, F3, FLT3, HSPA1A, INSR, MET, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
2.74482 |
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, EGFR, FLT3, HSD11B2, SRC |
2.73584 |
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, AURKB, BCL2, CSNK2A1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, HCAR2, HSPA1A, IGF1R, KDR, MET, MMP12, PPARA, PTPN1, SMAD3, SRC, TNKS, TNKS2, XDH |
2.73447 |
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, SRC, TEK |
2.69973 |
[BP] GO:0055080 |
cation homeostasis
|
ABCG2, BCL2, CA2, CA7, DRD1, DRD3, EGFR, ESR1, F2, GPR35, SMAD3 |
2.6687 |
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, F2, INSR, SMAD3, XDH |
2.66637 |
[BP] GO:0006811 |
None
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD3, FABP3, KCNA3, PPARA |
2.66267 |
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DUSP3, EGFR, F2, FABP4, FLT3, IGF1R, INSR, PTPN1, SRC, TEK, TNKS |
2.66199 |
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD3, DUSP3, ESR1, HSPA1A, IGF1R, MET, PTPN1, SRC, XDH |
2.65863 |
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
AURKB, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, MET, MMP12, PPARA, SMAD3, SRC, TNKS, TNKS2, TOP2A |
2.64851 |
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.64103 |
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, SRC |
2.61758 |
[BP] GO:0051130 |
positive regulation of cellular component organization
|
AURKB, AXL, BCL2, DRD3, ESR1, HSPA1A, IGF1R, INSR, KDR, MET, SMAD3, SRC, TEK, TNKS, TNKS2 |
2.60612 |
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.59879 |
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, AXL, BCL2, CA1, CA2, CDK6, CSNK2A1, CYP1B1, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2 |
2.56863 |
[BP] GO:0040008 |
regulation of growth
|
BCL2, CSNK2A1, DRD3, EGFR, ESR2, F2, HSPA1A, INSR, PIM1, SMAD3, TNKS2 |
2.53908 |
[BP] GO:0014066 |
regulation of phosphatidylinositol 3-kinase signaling
|
EGFR, F2, FLT3, KDR, TEK |
2.53448 |
[BP] GO:0043412 |
macromolecule modification
|
ALPL, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F2, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.53252 |
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, AXL, BCL2, CA1, CSNK2A1, EGFR, F2, F3, FLT3, GPR35, IGF1R, INSR, KDR, MET, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2 |
2.53086 |
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.52804 |
[BP] GO:0050678 |
None
|
CDK6, EGFR, F3, KDR, MMP12, SMAD3, TEK, XDH |
2.52677 |
[BP] GO:0048732 |
gland development
|
BCL2, CSNK2A1, CYP19A1, EGFR, INSR, SMAD3, TYR |
2.50752 |
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, FUT7, GBA2, HSPA1A, MMP12, SRC, XDH |
2.50097 |
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
2.50008 |
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, DRD1, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, INSR, SRC, TOP2A |
2.49067 |
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.47886 |
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.47886 |
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, MET, SRC |
2.47886 |
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, MET, SRC |
2.47886 |
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, SRC |
2.47886 |
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.47708 |
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, CSNK2A1, CYP19A1, CYP1A1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.47002 |
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.47002 |
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.47002 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.47002 |
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, IGF1R, INSR, PTPN1, SRC |
2.47002 |
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
2.46214 |
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, PTPN1, SMAD3, SRC, TEK |
2.46125 |
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, SRC |
2.45493 |
[BP] GO:0043550 |
regulation of lipid kinase activity
|
F2, FLT3, SRC, TEK |
2.45493 |
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ABCG2, ACHE, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, FUT7, GBA2, GLO1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
2.45345 |
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, BCL2, CDC25B, DRD1, DUSP3, EGFR, F2, FABP4, FLT3, IGF1R, INSR, KDR, PTPN1, SRC, TEK, XDH |
2.43527 |
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.4268 |
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.42599 |
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD3, EGFR, INSR, SMAD3 |
2.41086 |
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, EGFR, F2, FLT3, INSR, PTPN1, SRC, TEK, TNKS |
2.4103 |
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.40236 |
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.40236 |
[BP] GO:0030003 |
cellular cation homeostasis
|
ABCG2, BCL2, CA2, CA7, DRD1, DRD3, ESR1, F2, GPR35, SMAD3 |
2.40174 |
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AXL, BCL2, CA2, CA3, CA9, CYP1A1, CYP1A2, CYP1B1, DRD1, EGFR, F2, HSD11B2, HSPA1A, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, TOP2A |
2.38276 |
[BP] GO:0048729 |
tissue morphogenesis
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.36447 |
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, EGFR, HCAR2, MET, PPARA, SMAD3 |
2.34297 |
[BP] GO:0006873 |
cellular ion homeostasis
|
ABCG2, BCL2, CA2, CA7, DRD1, DRD3, ESR1, F2, GPR35, SMAD3 |
2.32529 |
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.32458 |
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DRD1, DRD3 |
2.31752 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.31504 |
[BP] GO:0050793 |
regulation of developmental process
|
AXL, BCL2, CA2, CDK6, CYP1B1, DRD3, EGFR, ESR1, ESRRA, ESRRB, F2, F3, INSR, KDR, NUAK1, PIM1, PPARA, SMAD3, SRC, TEK, TNKS2, XDH |
2.31493 |
[BP] GO:0048608 |
reproductive structure development
|
AXL, BCL2, CYP19A1, ESR1, HSD17B2, INSR, SRC |
2.28016 |
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TNKS, TNKS2 |
2.27433 |
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, CYP3A4 |
2.27433 |
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.26129 |
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, CDC25B, DUSP3, EGFR, F2, FABP4, FLT3, IGF1R, INSR, PTPN1, SRC, TEK |
2.25991 |
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, DUSP3, EGFR, FLT3, IGF1R, INSR, KDR, PTPN1, SRC, TEK, XDH |
2.25991 |
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
BCL2, CDK6, KDR, SMAD3, SRC, TEK |
2.2547 |
[BP] GO:1904356 |
regulation of telomere maintenance via telomere lengthening
|
AURKB, SRC, TNKS, TNKS2 |
2.2547 |
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, BCL2, CDC25B, EGFR, ESRRB, F2, FLT3, INSR, KDR, PTPN1, SRC, TEK, XDH |
2.2547 |
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, BCL2, CDC25B, DRD1, DUSP3, EGFR, F2, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, NUAK1, PTPN1, SRC, TEK, XDH |
2.24585 |
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F2, F3, FLT3, FUT7, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.23687 |
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1 |
2.23687 |
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.23687 |
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.23687 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.23687 |
[BP] GO:0043434 |
None
|
APEX1, FABP3, HSD11B2, INSR, PPARA, SRC, TEK |
2.2291 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.22563 |
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
EGFR, F2, F3, FABP4, KDR, MET, SMAD3 |
2.22209 |
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, F2, F3, FLT3, HSPA1A, INSR, KDR, PTPN1, SMAD3, SRC, TEK, XDH |
2.2143 |
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F2, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.21038 |
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR |
2.20974 |
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, CA2, CA7, DRD1, EGFR |
2.19403 |
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD3, EGFR, HCAR2, MMP12, SRC |
2.19368 |
[BP] GO:0016311 |
None
|
ALPL, APEX1, BCL2, CA3, CDC25B, DUSP3, PTPN1 |
2.18323 |
[BP] GO:0051128 |
regulation of cellular component organization
|
AURKB, AXL, BCL2, CSNK2A1, DRD3, EGFR, ESR1, ESR2, F2, HSPA1A, IGF1R, INSR, KDR, MET, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.18323 |
[BP] GO:0051894 |
None
|
KDR, SMAD3, TEK |
2.18227 |
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.18227 |
[BP] GO:2000573 |
positive regulation of DNA biosynthetic process
|
AURKB, SRC, TNKS, TNKS2 |
2.17714 |
[BP] GO:0050927 |
None
|
F3, KDR, SMAD3 |
2.13057 |
[BP] GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase signaling
|
F2, FLT3, KDR, TEK |
2.12752 |
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, ESR1, IGF1R, INSR, SRC |
2.11147 |
[BP] GO:0071702 |
None
|
ABCG2, ADORA1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD3, FABP3, MMP12, PPARA, TNKS |
2.09098 |
[BP] GO:0009968 |
negative regulation of signal transduction
|
BCL2, DRD3, DUSP3, EGFR, ESR1, ESR2, HSPA1A, IGF1R, MET, MMP12, PTPN1, SMAD3, SRC, XDH |
2.09055 |
[BP] GO:0006706 |
steroid catabolic process
|
CYP19A1, CYP1A2, CYP3A4 |
2.0889 |
[BP] GO:0050926 |
None
|
F3, KDR, SMAD3 |
2.0889 |
[BP] GO:1904353 |
regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.0889 |
[BP] GO:1903393 |
None
|
KDR, SMAD3, TEK |
2.0889 |
[BP] GO:0045913 |
None
|
ESRRB, INSR, PPARA, SRC |
2.08744 |
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, EGFR, FLT3, INSR, KDR, PTPN1, SRC, TEK, XDH |
2.08744 |
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1 |
2.06896 |
[BP] GO:0043696 |
None
|
CDK6, ESRRB |
2.06046 |
[BP] GO:0043697 |
None
|
CDK6, ESRRB |
2.06046 |
[BP] GO:0010641 |
None
|
F3, SRC |
2.06046 |
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, CA2, CA7, DRD1, DRD3, EGFR |
2.06025 |
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, CA2, CA7, DRD1, DRD3, EGFR |
2.06025 |
[BP] GO:1904357 |
None
|
SRC, TNKS, TNKS2 |
2.05779 |
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, AXL, BCL2, CA2, CDK6, CYP19A1, DUSP3, ESR1, ESRRA, F2, HCAR2, HSPA1A, MMP12, PTPN1, SMAD3, SRC |
2.01704 |
[BP] GO:0008209 |
androgen metabolic process
|
CYP19A1, CYP3A4, ESR1 |
2.0122 |
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, SRC, TEK |
2.012 |
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, BCL2, CDC25B, EGFR, ESR1, F2, F3, FLT3, HSPA1A, INSR, KDR, PTPN1, SMAD3, SRC, TEK, XDH |
2.01088 |
[BP] GO:0035239 |
tube morphogenesis
|
BCL2, EGFR, ESR1, MET, SMAD3, SRC |
2.00698 |
[BP] GO:0031099 |
regeneration
|
AXL, BCL2, CSNK2A1, EGFR, FLT3 |
2.00235 |
[CC] GO:0043227 |
membrane-bounded organelle
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSPA1A, IGF1R, INSR, KDR, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TNKS, TNKS2, TOP2A, TYR, XDH |
2.96801 |
[CC] GO:0044444 |
cytoplasmic part
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, AURKB, BCL2, CA1, CA2, CA3, CA4, CA5A, CA5B, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, F2, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, PIM1, PTPN1, SMAD3, SRC, TNKS, TNKS2, TOP2A, TYR, XDH |
2.77751 |
[CC] GO:0005886 |
plasma membrane
|
ABCG2, ACHE, ADORA1, ADORA3, ALPL, AXL, CA12, CA14, CA2, CA4, CA9, CSNK2A1, DRD1, DRD3, EGFR, ESR1, F2, F3, FLT3, GBA2, GLO1, GPR35, HCAR2, IGF1R, INSR, KCNA3, KDR, MET, PIM1, PTPN1, SMAD3, SRC, TEK |
2.56863 |
[CC] GO:0016020 |
membrane
|
ABCG2, ACHE, ADORA1, ADORA3, ALOX5, ALPL, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, EGFR, ESR1, F2, F3, FLT3, FUT7, GBA2, GLO1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B2, IGF1R, INSR, KCNA3, KDR, MET, PIM1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TYR |
2.50447 |
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, TEK |
2.27401 |
[CC] GO:0044432 |
endoplasmic reticulum part
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, EGFR, F2, FLT3, GBA2, HSD11B1, HSD11B2, HSD17B2, PTPN1 |
2.23687 |
[CC] GO:0043226 |
organelle
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSPA1A, IGF1R, INSR, KDR, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TNKS, TNKS2, TOP2A, TYR, XDH |
2.08586 |
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, EGFR, GBA2, HSD11B1, HSD11B2, HSD17B2 |
2.00912 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
19.5235 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, AOX1, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP12, PIM1, PPARA, PTPN1, SMAD3, TNKS, TYR, XDH |
14.3713 |
[MF] GO:0003824 |
catalytic activity
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DUSP3, EGFR, F2, F3, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PTPN1, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
13.2551 |
[MF] GO:0043167 |
ion binding
|
ABCG2, ACHE, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
12.6406 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
12.6406 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
12.535 |
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1 |
9.48158 |
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP12, PPARA, PTPN1, SMAD3, TNKS |
7.86218 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
7.17098 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, ALPL, AOX1, APEX1, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, ESR1, ESR2, ESRRA, ESRRB, F2, GLO1, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, TNKS, TNKS2, TOP2A, TYR, XDH |
6.93044 |
[MF] GO:0008144 |
drug binding
|
ABCG2, ACHE, AURKB, AXL, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PPARA, SRC, TEK, TOP2A |
6.70953 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.47053 |
[MF] GO:0046872 |
metal ion binding
|
ALOX5, ALPL, AOX1, APEX1, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F2, GLO1, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, TNKS, TNKS2, TOP2A, TYR, XDH |
5.54658 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2, TYR, XDH |
5.4168 |
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, PPARA, TEK |
5.17742 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4 |
5.17663 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
5.10282 |
[MF] GO:0005496 |
steroid binding
|
CYP3A4, ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1 |
5.00756 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4 |
4.94305 |
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
4.92357 |
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AXL, CDK6, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, PPARA, TEK |
4.8139 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
4.51384 |
[MF] GO:0005506 |
iron ion binding
|
ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, XDH |
4.44926 |
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, PPARA, TEK |
4.42567 |
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AXL, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, PPARA, SMAD3, TEK |
4.38588 |
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, PIM1, PPARA, PTPN1, SMAD3, SRC |
3.91372 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4 |
3.88235 |
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA |
3.7319 |
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA |
3.7319 |
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
3.71391 |
[MF] GO:0008289 |
lipid binding
|
AXL, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, HSD11B2, HSD17B1, PPARA |
3.6764 |
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, PPARA, PTPN1, SMAD3, SRC |
3.66505 |
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, TYR |
3.61402 |
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA |
3.39519 |
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.36786 |
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
3.33866 |
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.26665 |
[MF] GO:0016725 |
oxidoreductase activity, acting on CH or CH2 groups
|
CYP1A2, CYP3A4, XDH |
3.26107 |
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.26107 |
[MF] GO:0036094 |
small molecule binding
|
ABCG2, ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FABP3, FABP4, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP2A, XDH |
3.16039 |
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.14249 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, SRC |
2.99321 |
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, HSD11B2, HSD17B1, SRC, XDH |
2.8489 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, SRC |
2.83491 |
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.83126 |
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.83126 |
[MF] GO:0042562 |
hormone binding
|
ACHE, EGFR, HSD17B1, IGF1R, INSR |
2.76182 |
[MF] GO:0000166 |
nucleotide binding
|
ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP2A, XDH |
2.68873 |
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP2A, XDH |
2.6875 |
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK |
2.67158 |
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.6687 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, TYR |
2.61758 |
[MF] GO:0005524 |
ATP binding
|
ABCG2, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP2A |
2.60612 |
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, MET, PPARA, PTPN1, SMAD3 |
2.50447 |
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCG2, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP2A |
2.50097 |
[MF] GO:0019899 |
enzyme binding
|
AURKB, BCL2, CDC25B, CYP1A1, CYP1A2, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, HSPA1A, MET, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
2.48545 |
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCG2, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP2A |
2.47886 |
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.47002 |
[MF] GO:0043168 |
anion binding
|
ABCG2, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, F2, F3, FABP3, FABP4, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP2A, XDH |
2.39837 |
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, XDH |
2.37744 |
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD3, EGFR, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, TEK |
2.35875 |
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD3, EGFR, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, TEK |
2.35875 |
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.23687 |
[MF] GO:0034875 |
caffeine oxidase activity
|
CYP1A2, CYP3A4 |
2.23687 |
[MF] GO:0033695 |
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
|
CYP1A2, CYP3A4 |
2.23687 |
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCG2, ADORA1, AOX1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DRD1, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TOP2A, XDH |
2.08516 |
[MF] GO:0019838 |
growth factor binding
|
EGFR, IGF1R, INSR, KDR, TEK |
2.07321 |
[MF] GO:0101020 |
estrogen 16-alpha-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.06046 |
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2 |
2.06046 |
[MF] GO:0043559 |
insulin binding
|
IGF1R, INSR |
2.06046 |