GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, AKR1C3, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, FABP4, KDR, KIT, MMP9, PTGS2, SRC |
9.14198 |
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, AKR1C3, ALPL, APP, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, HSD17B2, IDO1, IGF1R, KDR, KIT, MMP2, MPO, PTGS2, RORC, SRC, TYR |
9.0473 |
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, AKR1C3, ALPL, APP, AXL, BCL2, CA9, CYP1A1, CYP1A2, CYP1B1, FABP3, HSD17B2, IDO1, IGF1R, MMP2, MMP9, MPO, PTGS2, RORC, SRC, TYR |
9.0102 |
[BP] GO:0033993 |
response to lipid
|
AKR1C3, ALPL, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, FABP3, FLT3, HSD17B2, IDO1, MPO, PTGS2, RORC, SRC, TYR |
9.00054 |
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, AKR1C3, BCL2, CYP1A1, CYP1A2, CYP1B1, TYR |
9.00054 |
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, AKR1C3, ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FUT7, IDO1, MPO, PIM1, PTGS2, TYR, XDH |
8.80184 |
[BP] GO:0042221 |
response to chemical
|
AKR1B1, AKR1C3, ALPL, APP, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, HSD17B2, IDO1, IGF1R, KDR, KIT, MMP2, MMP9, MPO, PTGS2, RORC, SRC, TYR |
8.25813 |
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.7184 |
[BP] GO:0043067 |
regulation of programmed cell death
|
AKR1B1, AKR1C3, AURKB, AXL, BCL2, CYP1B1, FLT3, HCAR2, IDO1, IGF1R, KDR, KIT, MET, MMP9, MPO, PIM1, PTGS2, PTPN1, SRC, XDH |
7.00523 |
[BP] GO:0010941 |
regulation of cell death
|
AKR1B1, AKR1C3, AURKB, AXL, BCL2, CYP1B1, FLT3, HCAR2, IDO1, IGF1R, KDR, KIT, MET, MMP9, MPO, PIM1, PTGS2, PTPN1, SRC, XDH |
6.50331 |
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA7, CA9 |
6.50331 |
[BP] GO:0010647 |
positive regulation of cell communication
|
AKR1B1, AKR1C3, APP, AXL, BCL2, CA2, CA7, CYP19A1, CYP1B1, FLT3, HCAR2, HTR6, KDR, KIT, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
6.50331 |
[BP] GO:0023056 |
positive regulation of signaling
|
AKR1B1, AKR1C3, APP, AXL, BCL2, CA2, CA7, CYP19A1, CYP1B1, FLT3, HCAR2, HTR6, KDR, KIT, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
6.49537 |
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, AKR1C3, ALPL, APP, AXL, BCL2, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, IGF1R, KDR, KIT, MMP2, MMP9, PTGS2, RORC, SRC |
6.39495 |
[BP] GO:0014070 |
response to organic cyclic compound
|
AKR1C3, ALPL, APP, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, FLT3, PTGS2, RORC, SRC, TYR |
6.1241 |
[BP] GO:0043069 |
negative regulation of programmed cell death
|
AKR1B1, AURKB, AXL, BCL2, IDO1, IGF1R, KDR, KIT, MET, MMP9, MPO, PIM1, PTGS2, PTPN1, SRC |
6.1241 |
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, AKR1B1, AKR1B10, AKR1C3, ALOX5, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, HSD17B2, KIT, MET, PTGS2 |
6.07219 |
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, AKR1C3, ALPL, APP, AXL, BCL2, CYP1A1, CYP1B1, FABP4, FLT3, IGF1R, KDR, KIT, MMP2, PTGS2, RORC, SRC |
6.03457 |
[BP] GO:0032502 |
developmental process
|
ACHE, AKR1B1, AKR1C3, ALPL, APP, AURKB, AXL, BCL2, CA2, CA9, CDC25B, CHRM2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, FUT7, HSD17B2, KDR, KIT, MET, MMP2, MMP9, MPO, PIM1, PTGS2, RORC, SRC, TYR |
5.9711 |
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, APP, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MPO, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
5.96043 |
[BP] GO:0060548 |
negative regulation of cell death
|
AKR1B1, AURKB, AXL, BCL2, IDO1, IGF1R, KDR, KIT, MET, MMP9, MPO, PIM1, PTGS2, PTPN1, SRC |
5.69839 |
[BP] GO:0010038 |
response to metal ion
|
AKR1C3, APP, BCL2, CA2, CYP1A1, CYP1A2, FABP4, KIT, MMP9, PTGS2 |
5.65411 |
[BP] GO:0042981 |
regulation of apoptotic process
|
AKR1B1, AKR1C3, AURKB, AXL, BCL2, CYP1B1, FLT3, HCAR2, IDO1, IGF1R, KDR, MMP9, MPO, PIM1, PTGS2, PTPN1, SRC, XDH |
5.6099 |
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
AKR1B1, AKR1C3, APP, AXL, BCL2, CYP1B1, FLT3, HTR6, KDR, KIT, MET, PTGS2, PTPN1, SRC, XDH |
5.59531 |
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, AKR1C3, ALPL, APP, AURKB, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, FABP4, FLT3, IGF1R, KDR, KIT, MMP2, MMP9, PTGS2, PTPN1, RORC, SRC |
5.59531 |
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, AKR1B1, AKR1C3, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CYP19A1, CYP1A1, CYP1B1, FABP3, FLT3, HCAR2, HTR6, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
5.59531 |
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, AKR1C3, ALPL, APP, BCL2, CA2, CA9, CYP1A2, FABP3, FLT3, IGF1R, KIT, MMP2, PTGS2, SRC |
5.58289 |
[BP] GO:0032501 |
multicellular organismal process
|
AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, APP, AXL, BCL2, CYP19A1, CYP1A2, CYP1B1, FABP4, HSD17B2, IDO1, IGF1R, KIT, MET, MMP1, MMP2, MMP9, MPO, PIM1, PTGS2, RORC, SRC, TYR |
5.55905 |
[BP] GO:0008152 |
metabolic process
|
ACHE, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, APP, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA7, CA9, CDC25B, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, MPO, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
5.50132 |
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, AKR1C3, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD17B2 |
5.49229 |
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, AKR1C3, APP, AXL, BCL2, CYP1B1, MMP9, MPO, PTGS2, SRC |
5.46327 |
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, AKR1C3, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD17B2, IDO1, MPO, PTGS2, TYR, XDH |
5.22024 |
[BP] GO:0042127 |
regulation of cell proliferation
|
AKR1B1, AKR1C3, APP, BCL2, CDC25B, CYP1B1, FABP3, FLT3, IDO1, IGF1R, KDR, KIT, MMP2, MMP9, PIM1, PTGS2, SRC, XDH |
5.18628 |
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, AKR1B1, AKR1C3, APP, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CYP19A1, CYP1A1, CYP1B1, FABP3, FABP4, FLT3, HCAR2, HTR6, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
5.08992 |
[BP] GO:0009725 |
response to hormone
|
AKR1B1, AKR1C3, ALPL, BCL2, CA2, CA9, CYP1A2, FABP3, FLT3, KIT, PTGS2, SRC |
4.83701 |
[BP] GO:0022414 |
reproductive process
|
AKR1B1, AKR1C3, ALPL, APP, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, HSD17B2, IDO1, KIT, MMP2, MMP9, PTGS2, SRC |
4.71015 |
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.65794 |
[BP] GO:0043066 |
negative regulation of apoptotic process
|
AKR1B1, AURKB, AXL, BCL2, IDO1, IGF1R, KDR, MMP9, MPO, PIM1, PTGS2, PTPN1, SRC |
4.58041 |
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
AKR1B1, AKR1C3, APP, AURKB, AXL, BCL2, CYP1B1, FLT3, HTR6, IGF1R, KDR, KIT, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
4.54149 |
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, AKR1B1, AKR1C3, APP, AURKB, AXL, BCL2, CA12, CA2, CA7, CYP19A1, CYP1A1, CYP1B1, FABP3, FABP4, FLT3, HCAR2, HSD17B2, KDR, KIT, MET, PTGS2, SRC, XDH |
4.5112 |
[BP] GO:0009056 |
catabolic process
|
ACHE, AKR1B10, AKR1C3, AURKB, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, IDO1, MMP1, MMP2, MMP9, MPO, SRC, XDH |
4.5112 |
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
4.37958 |
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
AKR1C3, ALPL, APP, CYP1A1, CYP1B1, FLT3, PTGS2, RORC, SRC |
4.35066 |
[BP] GO:0050896 |
response to stimulus
|
ACHE, AKR1B1, AKR1C3, ALPL, APP, AURKB, AXL, BCL2, CA2, CA9, CHRM2, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, HSD17B2, IDO1, IGF1R, KDR, KIT, MMP2, MMP9, MPO, PTGS2, PTPN1, RORC, SRC, TYR |
4.34385 |
[BP] GO:0019216 |
regulation of lipid metabolic process
|
AKR1C3, CYP1A1, FABP3, FLT3, HCAR2, KIT, PTGS2, RORC, SRC |
4.24158 |
[BP] GO:0006690 |
icosanoid metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
4.22818 |
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AKR1C3, AXL, BCL2, CYP1B1, MMP9, SRC |
4.22454 |
[BP] GO:0019369 |
arachidonic acid metabolic process
|
AKR1C3, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
4.21225 |
[BP] GO:0048584 |
positive regulation of response to stimulus
|
AKR1B1, AKR1C3, APP, AXL, BCL2, CYP1B1, FABP4, FLT3, HTR6, IDO1, KDR, KIT, MET, MMP2, MMP9, PTGS2, PTPN1, SRC, XDH |
4.20413 |
[BP] GO:0048856 |
anatomical structure development
|
ACHE, AKR1B1, AKR1C3, ALPL, APP, AXL, BCL2, CA2, CHRM2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, HSD17B2, KDR, KIT, MMP9, PIM1, PTGS2, RORC, SRC, TYR |
4.20413 |
[BP] GO:0009967 |
positive regulation of signal transduction
|
AKR1B1, AKR1C3, APP, AXL, BCL2, CYP1B1, FLT3, HTR6, KDR, KIT, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
4.17874 |
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, HSD17B2 |
4.1777 |
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AKR1C3, AXL, CYP1B1, MMP9, SRC |
4.1777 |
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, FLT3, IGF1R, KDR, KIT, MET, MMP2, MMP9, PTPN1, SRC |
4.17039 |
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, KIT, MET, PTGS2 |
4.12849 |
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, HSD17B2 |
4.1203 |
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CYP1A1, CYP1A2, IDO1, MPO, PTGS2, SRC |
4.11696 |
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
4.11599 |
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1, MPO |
4.08793 |
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
4.08015 |
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, FLT3, IGF1R, KDR, KIT, PIM1, SRC |
3.97875 |
[BP] GO:0048513 |
animal organ development
|
ACHE, AKR1C3, AXL, BCL2, CA2, CYP19A1, CYP1A1, CYP1A2, FLT3, HSD17B2, KDR, KIT, SRC, TYR |
3.97212 |
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CYP1A1, CYP1A2, IDO1, MPO, PTGS2, SRC |
3.93689 |
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, AKR1B1, AKR1C3, APP, AURKB, AXL, BCL2, CA2, CA7, CYP19A1, CYP1B1, FLT3, HCAR2, HTR6, IGF1R, KDR, KIT, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
3.91342 |
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, AKR1C3, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, TYR |
3.90713 |
[BP] GO:0023051 |
regulation of signaling
|
ACHE, AKR1B1, AKR1C3, APP, AURKB, AXL, BCL2, CA2, CA7, CYP19A1, CYP1B1, FLT3, HCAR2, HTR6, IGF1R, KDR, KIT, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
3.8272 |
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, AKR1C3, CYP19A1, IDO1 |
3.80826 |
[BP] GO:0009991 |
response to extracellular stimulus
|
AKR1C3, ALPL, AXL, BCL2, CYP1A1, MPO, PTGS2, SRC, TYR |
3.76999 |
[BP] GO:0044598 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.76999 |
[BP] GO:0044597 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.76999 |
[BP] GO:0030638 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.76999 |
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AKR1C3, BCL2, CDC25B, FLT3, IGF1R, KDR, KIT, MMP2, MMP9, PIM1, PTGS2 |
3.7466 |
[BP] GO:0048545 |
response to steroid hormone
|
AKR1C3, ALPL, BCL2, CA2, FLT3, PTGS2, SRC |
3.72033 |
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, AKR1C3, FABP3, HSD17B2, KDR, MMP2, PTGS2, SRC |
3.719 |
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, BCL2, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
3.719 |
[BP] GO:0030647 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.6181 |
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, BCL2, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
3.60004 |
[BP] GO:0003006 |
developmental process involved in reproduction
|
AKR1C3, ALPL, AXL, BCL2, CDC25B, CYP19A1, HSD17B2, KIT, PTGS2, SRC |
3.5909 |
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, AKR1C3, APP, AXL, CYP1B1, IGF1R, MMP2, MMP9, PTGS2, RORC, SRC |
3.5909 |
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALPL, APP, AURKB, AXL, BCL2, CDC25B, FLT3, IGF1R, KDR, KIT, MET, PIM1, PTGS2, PTPN1, SRC, XDH |
3.57436 |
[BP] GO:0071248 |
cellular response to metal ion
|
AKR1C3, CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
3.53827 |
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, FLT3, IGF1R, KDR, KIT, MET, PIM1, SRC |
3.53118 |
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, BCL2, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
3.52589 |
[BP] GO:0030334 |
regulation of cell migration
|
APP, BCL2, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
3.50709 |
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.50323 |
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, IDO1, KIT, PTGS2 |
3.49351 |
[BP] GO:0031960 |
response to corticosteroid
|
AKR1C3, ALPL, BCL2, FLT3, PTGS2, SRC |
3.45464 |
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
3.45464 |
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, BCL2, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
3.42787 |
[BP] GO:0002320 |
lymphoid progenitor cell differentiation
|
BCL2, FLT3, KIT |
3.39002 |
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALPL, APP, AURKB, AXL, BCL2, CDC25B, FLT3, IGF1R, KDR, KIT, MET, PIM1, PTGS2, PTPN1, SRC, XDH |
3.35072 |
[BP] GO:0008283 |
cell proliferation
|
ACHE, AURKB, BCL2, CYP1A1, FLT3, KIT, MET, PIM1, SRC, TYR |
3.31467 |
[BP] GO:0002521 |
leukocyte differentiation
|
AXL, BCL2, FLT3, FUT7, KIT, MMP9, RORC |
3.30943 |
[BP] GO:2000145 |
regulation of cell motility
|
APP, BCL2, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
3.28981 |
[BP] GO:0009628 |
response to abiotic stimulus
|
AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, KIT, MMP2, MPO, PTGS2, SRC, TYR |
3.28289 |
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, MMP9, PTGS2, PTPN1, SRC |
3.25336 |
[BP] GO:0071241 |
cellular response to inorganic substance
|
AKR1C3, CYP1A1, CYP1A2, FABP4, MMP9, PTGS2 |
3.23717 |
[BP] GO:0048608 |
reproductive structure development
|
AKR1C3, AXL, BCL2, CYP19A1, HSD17B2, KIT, SRC |
3.23717 |
[BP] GO:0016042 |
lipid catabolic process
|
AKR1B10, AKR1C3, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4 |
3.23717 |
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, KIT, SRC |
3.23717 |
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, FLT3, IGF1R, KDR, KIT, MET, MMP2, MMP9, PTPN1, SRC |
3.2312 |
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AKR1C3, CYP1A1, CYP1A2, CYP1B1, IDO1, MPO |
3.20708 |
[BP] GO:0048869 |
cellular developmental process
|
ACHE, AKR1C3, ALPL, APP, AXL, BCL2, CDC25B, CYP1A1, FABP4, FLT3, FUT7, KDR, KIT, MET, MMP2, MMP9, PTGS2, RORC, SRC |
3.2019 |
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
AKR1C3, CYP1A1, CYP1A2, CYP1B1, PTGS2 |
3.17771 |
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, AXL, BCL2, CYP1A1, CYP1B1, KDR, SRC |
3.14318 |
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, MPO |
3.14318 |
[BP] GO:0031667 |
response to nutrient levels
|
AKR1C3, ALPL, BCL2, CYP1A1, MPO, PTGS2, SRC, TYR |
3.12337 |
[BP] GO:0030098 |
lymphocyte differentiation
|
AXL, BCL2, FLT3, FUT7, KIT, RORC |
3.05776 |
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, AKR1C3, CYP1A1, CYP1A2, CYP1B1 |
3.05776 |
[BP] GO:0016488 |
None
|
AKR1B10, AKR1C3 |
3.05776 |
[BP] GO:0016487 |
None
|
AKR1B10, AKR1C3 |
3.05776 |
[BP] GO:0016107 |
None
|
AKR1B10, AKR1C3 |
3.05776 |
[BP] GO:0006714 |
None
|
AKR1B10, AKR1C3 |
3.05776 |
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, AXL, BCL2, CYP1B1, SRC |
3.05458 |
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3 |
3.05458 |
[BP] GO:0040012 |
regulation of locomotion
|
APP, BCL2, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
3.04765 |
[BP] GO:0006631 |
fatty acid metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, PTGS2 |
3.04432 |
[BP] GO:0051270 |
regulation of cellular component movement
|
APP, BCL2, CYP19A1, CYP1B1, IGF1R, KDR, KIT, MET, MMP9, PTGS2, SRC |
3.03984 |
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, AKR1C3, AXL, CYP1B1, MMP9, SRC |
3.02225 |
[BP] GO:0042493 |
response to drug
|
AKR1B1, AXL, BCL2, CA9, CYP1A1, CYP1B1, FABP3, KDR, PTGS2, SRC |
2.97122 |
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
APP, BCL2, CDC25B, FABP3, FLT3, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.96889 |
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
APP, BCL2, CDC25B, FABP3, FLT3, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.96889 |
[BP] GO:0044283 |
None
|
AKR1B1, AKR1C3, ALOX5, CYP19A1, CYP1A1, IDO1, MPO, PTGS2 |
2.92818 |
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
APP, AXL, BCL2, CA2, CYP1B1, HCAR2, IDO1, KDR, KIT, MET, MMP9, PIM1, PTGS2, SRC |
2.92818 |
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, SRC |
2.9027 |
[BP] GO:0046686 |
response to cadmium ion
|
AKR1C3, CYP1A2, KIT, MMP9 |
2.87166 |
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
2.84702 |
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AKR1C3, AXL, KIT, MET, SRC, XDH |
2.83973 |
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
APP, BCL2, CDC25B, FLT3, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.83808 |
[BP] GO:0043436 |
oxoacid metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, IDO1, MPO, PIM1, PTGS2, TYR |
2.83224 |
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, KIT, PTGS2, SRC |
2.83003 |
[BP] GO:0043065 |
positive regulation of apoptotic process
|
AKR1C3, BCL2, CYP1B1, HCAR2, IDO1, MMP9, PTGS2, SRC, XDH |
2.81743 |
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, AKR1C3, CYP1A1, CYP1A2, CYP1B1 |
2.8065 |
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC |
2.8065 |
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, FLT3, IGF1R, KDR, KIT, MET, PIM1, SRC |
2.8065 |
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, FLT3, FUT7, KIT, MMP9, MPO, RORC, SRC |
2.80151 |
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.80043 |
[BP] GO:0043068 |
positive regulation of programmed cell death
|
AKR1C3, BCL2, CYP1B1, HCAR2, IDO1, MMP9, PTGS2, SRC, XDH |
2.79946 |
[BP] GO:0006082 |
organic acid metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, IDO1, MPO, PIM1, PTGS2, TYR |
2.78405 |
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, AKR1C3, CYP19A1, HSD17B2 |
2.76092 |
[BP] GO:0001932 |
regulation of protein phosphorylation
|
APP, BCL2, CDC25B, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.76025 |
[BP] GO:0032844 |
regulation of homeostatic process
|
AURKB, BCL2, CA2, CA7, HCAR2, KDR, PTGS2, SRC |
2.72936 |
[BP] GO:0032787 |
None
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, IDO1, PTGS2 |
2.70564 |
[BP] GO:0009605 |
response to external stimulus
|
AKR1C3, ALPL, AXL, BCL2, CHRM2, CYP1A1, CYP1A2, IDO1, KIT, MPO, PTGS2, SRC, TYR |
2.6998 |
[BP] GO:0042327 |
positive regulation of phosphorylation
|
APP, BCL2, CDC25B, FLT3, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.6998 |
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.69184 |
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.69184 |
[BP] GO:0043207 |
response to external biotic stimulus
|
ALPL, AXL, BCL2, CHRM2, CYP1A1, CYP1A2, IDO1, MPO, PTGS2, SRC |
2.69184 |
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.69184 |
[BP] GO:0016095 |
None
|
AKR1B10, AKR1C3 |
2.69184 |
[BP] GO:0006950 |
response to stress
|
ACHE, AKR1B1, AKR1C3, APP, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, IDO1, KIT, MMP2, MMP9, MPO, PTGS2, PTPN1, SRC |
2.61894 |
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.58666 |
[BP] GO:0010942 |
positive regulation of cell death
|
AKR1C3, BCL2, CYP1B1, HCAR2, IDO1, MMP9, PTGS2, SRC, XDH |
2.58497 |
[BP] GO:0009607 |
response to biotic stimulus
|
ALPL, AXL, BCL2, CHRM2, CYP1A1, CYP1A2, IDO1, MPO, PTGS2, SRC |
2.55298 |
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, HCAR2, HSD17B2 |
2.55286 |
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B2 |
2.53884 |
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, KIT, SRC |
2.52357 |
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, IGF1R, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
2.51144 |
[BP] GO:0019752 |
carboxylic acid metabolic process
|
AKR1C3, ALOX5, CYP1A1, CYP1A2, CYP1B1, FABP3, IDO1, PIM1, PTGS2, TYR |
2.49484 |
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, AKR1C3, APP, FLT3, IGF1R, KIT, MMP2, PTGS2, SRC |
2.48952 |
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AKR1C3, AXL, KIT, MET, SRC |
2.46811 |
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, AKR1B1, AKR1C3, APP, AURKB, AXL, BCL2, CYP19A1, CYP1B1, FABP3, FABP4, IDO1, IGF1R, KDR, KIT, MET, MMP9, MPO, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
2.46027 |
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, MMP2, MMP9, PTGS2 |
2.44889 |
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.43447 |
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
APP, BCL2, CDC25B, FABP3, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.43447 |
[BP] GO:0046427 |
positive regulation of JAK-STAT cascade
|
AKR1B1, CYP1B1, FLT3, KIT |
2.43447 |
[BP] GO:0042325 |
regulation of phosphorylation
|
APP, BCL2, CDC25B, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.43447 |
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, APP, AURKB, AXL, BCL2, CDC25B, CYP1A1, CYP1A2, FLT3, FUT7, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, PIM1, PTGS2, PTPN1, SRC, TYR, XDH |
2.42896 |
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, MMP9, PTGS2, PTPN1, SRC |
2.41186 |
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
APP, BCL2, CDC25B, FABP3, FABP4, FLT3, IGF1R, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.4071 |
[BP] GO:1904894 |
positive regulation of STAT cascade
|
AKR1B1, CYP1B1, FLT3, KIT |
2.40216 |
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9, FABP3 |
2.38612 |
[BP] GO:0070542 |
None
|
AKR1C3, FABP3, PTGS2, SRC |
2.38487 |
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, APP, AURKB, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, MPO, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
2.37475 |
[BP] GO:0044238 |
primary metabolic process
|
ACHE, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, APP, AURKB, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, FUT7, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
2.37475 |
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, CYP19A1, CYP1A2, IDO1, XDH |
2.37475 |
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AKR1B10, AKR1C3, AURKB, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, IDO1, MPO, SRC, XDH |
2.36224 |
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HCAR2, IDO1 |
2.35513 |
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, PTGS2, TYR |
2.35513 |
[BP] GO:0033280 |
response to vitamin D
|
ALPL, PTGS2, TYR |
2.34477 |
[BP] GO:0048534 |
hematopoietic or lymphoid organ development
|
BCL2, FLT3, KDR, KIT, TYR |
2.32607 |
[BP] GO:1901575 |
None
|
ACHE, AKR1B10, AKR1C3, AURKB, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FUT7, IDO1, XDH |
2.32381 |
[BP] GO:1901661 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
2.31378 |
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC |
2.31378 |
[BP] GO:0042743 |
hydrogen peroxide metabolic process
|
CYP1A1, CYP1A2, MPO |
2.31378 |
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
AKR1C3, BCL2, CYP1B1, PTGS2, XDH |
2.31138 |
[BP] GO:0030154 |
cell differentiation
|
AKR1C3, ALPL, AXL, BCL2, CYP1A1, FABP4, FLT3, FUT7, KDR, KIT, MMP2, MMP9, PTGS2, RORC |
2.30273 |
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
AKR1C3, MMP1, MMP2, MMP9 |
2.29586 |
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, AXL, CYP1B1, KDR, PTGS2, SRC |
2.29083 |
[BP] GO:0071276 |
cellular response to cadmium ion
|
AKR1C3, CYP1A2, MMP9 |
2.28199 |
[BP] GO:0061370 |
testosterone biosynthetic process
|
AKR1C3, CYP19A1 |
2.27849 |
[BP] GO:0002318 |
myeloid progenitor cell differentiation
|
FLT3, KIT |
2.27849 |
[BP] GO:0044242 |
None
|
AKR1B10, AKR1C3, CYP1B1, FABP3, FABP4 |
2.27849 |
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, KIT, PTGS2, TYR |
2.27681 |
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, AKR1B1, AKR1C3, APP, AURKB, AXL, BCL2, CYP19A1, CYP1B1, FABP3, FABP4, HCAR2, IDO1, IGF1R, KDR, KIT, MET, MMP9, MPO, PIM1, PTGS2, PTPN1, RORC, SRC, XDH |
2.25464 |
[BP] GO:0042592 |
homeostatic process
|
AKR1B1, APP, AXL, BCL2, CA12, CA2, CA7, FABP3, FABP4, FLT3, MET, SRC |
2.25034 |
[BP] GO:0001523 |
None
|
AKR1B10, AKR1C3, CYP1A1, CYP1B1 |
2.23757 |
[BP] GO:0032879 |
regulation of localization
|
ACHE, APP, AXL, BCL2, CA2, CA7, CYP19A1, CYP1B1, HCAR2, IGF1R, KDR, KIT, MET, MMP9, PTGS2, PTPN1, SRC |
2.22321 |
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APP, FABP3, FLT3, IGF1R, MMP2, PTGS2, SRC, TYR |
2.21809 |
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC |
2.21809 |
[BP] GO:0048583 |
regulation of response to stimulus
|
AKR1B1, AKR1C3, APP, AURKB, AXL, BCL2, CYP19A1, CYP1B1, FABP4, FLT3, HTR6, IDO1, IGF1R, KDR, KIT, MET, MMP2, MMP9, PTGS2, PTPN1, SRC, XDH |
2.21665 |
[BP] GO:0044092 |
negative regulation of molecular function
|
APP, AURKB, CYP1B1, FABP4, IGF1R, MET, MMP9, PIM1, PTGS2, PTPN1, SRC |
2.18217 |
[BP] GO:0051130 |
positive regulation of cellular component organization
|
APP, AURKB, AXL, BCL2, IGF1R, KDR, KIT, MET, MMP1, MMP9, SRC |
2.16729 |
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, APP, CA2, CA7, KIT, PTGS2 |
2.16591 |
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, APP, CA2, CA7, KIT, PTGS2 |
2.16591 |
[BP] GO:0051902 |
negative regulation of mitochondrial depolarization
|
BCL2, SRC |
2.13694 |
[BP] GO:0016115 |
None
|
AKR1B10, AKR1C3 |
2.13694 |
[BP] GO:0016101 |
None
|
AKR1B10, AKR1C3, CYP1A1, CYP1B1 |
2.13694 |
[BP] GO:0030198 |
extracellular matrix organization
|
APP, CYP1B1, KDR, MMP1, MMP2, MMP9 |
2.1251 |
[BP] GO:0043062 |
extracellular structure organization
|
APP, CYP1B1, KDR, MMP1, MMP2, MMP9 |
2.11909 |
[BP] GO:0030217 |
None
|
BCL2, FUT7, KIT, RORC |
2.10841 |
[BP] GO:0034405 |
response to fluid shear stress
|
CA2, PTGS2, SRC |
2.09694 |
[BP] GO:0007584 |
response to nutrient
|
AKR1C3, ALPL, CYP1A1, PTGS2, TYR |
2.09694 |
[BP] GO:0031401 |
positive regulation of protein modification process
|
APP, BCL2, CDC25B, FLT3, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH |
2.07282 |
[BP] GO:0007566 |
embryo implantation
|
MMP2, MMP9, PTGS2 |
2.06608 |
[BP] GO:0046649 |
lymphocyte activation
|
AXL, BCL2, FLT3, FUT7, KIT, RORC |
2.04602 |
[BP] GO:1904180 |
negative regulation of membrane depolarization
|
BCL2, SRC |
2.01394 |
[BP] GO:0044236 |
multicellular organism metabolic process
|
AKR1C3, MMP1, MMP2, MMP9 |
2.01067 |
[BP] GO:0061515 |
None
|
APP, KIT, SRC |
2.01067 |
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APP, FABP3, FLT3, IGF1R, MMP2, PTGS2, SRC, TYR |
2.01009 |
[BP] GO:0051186 |
None
|
AKR1B1, AKR1B10, AKR1C3, CYP1A1, CYP1A2, MPO, PTGS2 |
2.00502 |
[CC] GO:0000323 |
lytic vacuole
|
AKR1B1, AKR1B10, KIT, MPO, SRC, TYR |
2.34251 |
[CC] GO:0005764 |
lysosome
|
AKR1B1, AKR1B10, KIT, MPO, SRC, TYR |
2.34251 |
[CC] GO:0097443 |
sorting endosome
|
KDR, PTPN1 |
2.13694 |
[CC] GO:0005773 |
None
|
AKR1B1, AKR1B10, KIT, MPO, SRC, TYR |
1.92645 |
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP |
1.92474 |
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
10.4296 |
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, APP, CA1, CA12, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, MMP1, MMP2, MMP9, PIM1, PTPN1, RORC, TYR, XDH |
9.14198 |
[MF] GO:0003824 |
catalytic activity
|
ACHE, AKR1B1, AKR1B10, AKR1C3, ALOX5, ALPL, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CDC25B, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, FUT7, HSD17B2, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, MPO, PIM1, PTGS2, PTPN1, SRC, TYR, XDH |
8.90275 |
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
7.04073 |
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX5, ALPL, APP, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FABP3, FABP4, FLT3, IDO1, IGF1R, KDR, KIT, MET, MMP1, MMP2, MMP9, MPO, PIM1, PTGS2, PTPN1, RORC, SRC, TYR, XDH |
6.74395 |
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
6.28758 |
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, MPO, PTGS2, SRC |
6.18506 |
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, AKR1C3, ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, HSD17B2, IDO1, MPO, PTGS2, TYR, XDH |
6.11977 |
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, MPO, PTGS2, SRC |
6.03332 |
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET |
5.4156 |
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, ALPL, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, KIT, MMP1, MMP2, MMP9, MPO, PIM1, PTGS2, PTPN1, RORC, TYR, XDH |
5.22024 |
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET |
4.83275 |
[MF] GO:0046872 |
metal ion binding
|
ALOX5, ALPL, APP, AURKB, CA1, CA12, CA14, CA2, CA4, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, KIT, MMP1, MMP2, MMP9, MPO, PIM1, PTGS2, PTPN1, RORC, TYR, XDH |
4.75223 |
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
AKR1C3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, PTGS2, TYR |
4.5112 |
[MF] GO:0004497 |
monooxygenase activity
|
AKR1C3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, TYR |
4.42611 |
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, FLT3, IGF1R, KDR, KIT, MET, SRC |
4.16065 |
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
4.13112 |
[MF] GO:0016829 |
lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA7, CA9 |
4.12849 |
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.96316 |
[MF] GO:0048037 |
cofactor binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, IDO1, MPO, PTGS2, SRC, XDH |
3.45464 |
[MF] GO:0005506 |
iron ion binding
|
ALOX5, CYP19A1, CYP1A1, CYP1A2, CYP1B1, XDH |
3.38633 |
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA7, CA9, MMP1, MMP2, MMP9, PTPN1, RORC |
3.33994 |
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AKR1C3, XDH |
3.20708 |
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1 |
3.17771 |
[MF] GO:0045550 |
None
|
AKR1B10, AKR1C3 |
3.05776 |
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, CYP19A1, CYP1A2, IDO1, XDH |
3.05458 |
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CHRM2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, FLT3, IGF1R, KDR, KIT, MET, PIM1, SRC |
3.02425 |
[MF] GO:0047718 |
None
|
AKR1B10, AKR1C3 |
2.69184 |
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AKR1C3, HSD17B2, XDH |
2.67259 |
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, FLT3, IGF1R, KDR, KIT, MET, PIM1, SRC |
2.6195 |
[MF] GO:0004033 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
2.44981 |
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX5, IDO1, PTGS2 |
2.44981 |
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX5, IDO1, PTGS2 |
2.41478 |
[MF] GO:0005158 |
None
|
IGF1R, PTPN1, SRC |
2.28199 |
[MF] GO:0004064 |
arylesterase activity
|
CA1, CA2 |
2.13694 |
[MF] GO:0047035 |
testosterone dehydrogenase (NAD+) activity
|
AKR1C3, HSD17B2 |
2.13694 |
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, FLT3, IGF1R, KDR, KIT, MET, PIM1, SRC |
2.13694 |
[MF] GO:0005021 |
vascular endothelial growth factor-activated receptor activity
|
FLT3, KDR |
2.01394 |
[MF] GO:0001758 |
None
|
AKR1B10, AKR1C3 |
2.01394 |
[MF] GO:0004032 |
None
|
AKR1B1, AKR1C3 |
2.01394 |