Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC13	TCMT23	Alkaline phosphatase, tissue-nonspecific isozyme	Homo sapiens	IC50: 407 (nM), Ref:
TCMC1956	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 1080 (nM), Ref: 21282059
TCMC1956	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 470 (nM), Ref: 21282059
TCMC1956	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 4450 (nM), Ref: 21282059
TCMC1956	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4090 (nM), Ref: 21282059
TCMC1956	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 4720 (nM), Ref: 21669522 Ki: 4720 (nM), Ref: 22687439
TCMC1956	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 2450 (nM), Ref: 22687439
TCMC1956	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 690 (nM), Ref: 22668600
TCMC1956	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 7870 (nM), Ref: 22668600
TCMC850	TCMT307	HERG	Homo sapiens	IC50: 4897.79 (nM), Ref: 21185626
TCMC850	TCMT707	Adenosine A2a receptor	Homo sapiens	Ki: 5011.87 (nM), Ref: 21661720 Ki: 9560 (nM), Ref: 23200243 Ki: 2480 (nM), Ref: 23200243
TCMC850	TCMT131	Acetylcholinesterase	Homo sapiens	IC50: 7250 (nM), Ref: 23791077
TCMC1115	TCMT860	Histone deacetylase 10	Homo sapiens	IC50: 8100 (nM), Ref: 24328302
TCMC1115	TCMT555	Histone deacetylase 6	Homo sapiens	IC50: 6500 (nM), Ref: 24328302
TCMC1115	TCMT691	Histone deacetylase 8	Homo sapiens	IC50: 2100 (nM), Ref: 24328302
TCMC1115	TCMT690	Histone deacetylase 3	Homo sapiens	IC50: 6900 (nM), Ref: 24328302
TCMC1115	TCMT556	Histone deacetylase 2	Homo sapiens	IC50: 9100 (nM), Ref: 24328302
TCMC1115	TCMT557	Histone deacetylase 1	Homo sapiens	IC50: 8800 (nM), Ref: 24328302
TCMC1115	TCMT370	Vascular endothelial growth factor receptor 2	Homo sapiens	IC50: 390 (nM), Ref: 24328302
TCMC1115	TCMT212	Tyrosine-protein kinase SRC	Homo sapiens	IC50: 490 (nM), Ref: 24328302
TCMC1115	TCMT791	Protein kinase N1	Homo sapiens	IC50: 9000 (nM), Ref: 24328302
TCMC1115	TCMT484	Serine/threonine-protein kinase PLK1	Homo sapiens	IC50: 6310 (nM), Ref: 24328302
TCMC1115	TCMT239	Serine/threonine-protein kinase PIM1	Homo sapiens	IC50: 4440 (nM), Ref: 24328302
TCMC1115	TCMT462	Serine/threonine-protein kinase NEK6	Homo sapiens	IC50: 1850 (nM), Ref: 24328302
TCMC1115	TCMT445	Serine/threonine-protein kinase NEK2	Homo sapiens	IC50: 3780 (nM), Ref: 24328302
TCMC1115	TCMT401	Hepatocyte growth factor receptor	Homo sapiens	IC50: 1120 (nM), Ref: 24328302
TCMC1115	TCMT369	Insulin-like growth factor I receptor	Homo sapiens	IC50: 150 (nM), Ref: 24328302
TCMC1115	TCMT441	Focal adhesion kinase 1	Homo sapiens	IC50: 800 (nM), Ref: 24328302
TCMC1115	TCMT388	Tyrosine-protein kinase receptor UFO	Homo sapiens	IC50: 220 (nM), Ref: 24328302
TCMC1115	TCMT374	Serine/threonine-protein kinase Aurora-B	Homo sapiens	IC50: 7290 (nM), Ref: 24328302
TCMC1115	TCMT436	NUAK family SNF1-like kinase 1	Homo sapiens	IC50: 3770 (nM), Ref: 24328302
TCMC1115	TCMT402	ALK tyrosine kinase receptor	Homo sapiens	IC50: 250 (nM), Ref: 24328302
TCMC1115	TCMT479	Serine/threonine-protein kinase AKT	Homo sapiens	IC50: 4070 (nM), Ref: 24328302
TCMC49	TCMT651	Dopamine D3 receptor	Homo sapiens	Ki: 500 (nM), Ref: 24559070
TCMC49	TCMT38	Dopamine D2 receptor	Homo sapiens	Ki: 5000 (nM), Ref: 24559070
TCMC897	TCMT223	Aldose reductase	Homo sapiens	IC50: 300 (nM), Ref: 22236472 IC50: 1800 (nM), Ref: 22261024
TCMC897	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 7900 (nM), Ref: 22236472

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC13	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 34.1 (ug/ml), Ref: 10425115
TCMC13	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 1.92 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC913	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 65.55 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC913	TCMT1189	Pseudomonas fluorescens	Pseudomonas fluorescens	MIC: 1.6 (ug/ml), Ref: 14995101
TCMC1936	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 14 (ug/ml), Ref: 10425115
TCMC2580	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 100 (ug/ml), Ref: 12398535
TCMC2580	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 17.2 (ug/ml), Ref: 10425115
TCMC2633	TCMT1286	Bacillus cereus	Bacillus cereus	MIC: 100 (ug/ml), Ref: 10425115
TCMC2633	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 5.8 (ug/ml), Ref: 10425115
TCMC1939	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 4.3 (ug/ml), Ref: 10425115
TCMC2675	TCMT1175	Human immunodeficiency virus	Human immunodeficiency virus	IC50: 8.3 (ug/ml), Ref: 10425115
TCMC897	TCMT1346	Helicobacter pylori	Helicobacter pylori	MIC: 6.25 (ug/ml), Ref: 12762812